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  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)

SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)

货号:CL-0208

规格:1×10⁶cells/T25培养瓶

价格: ¥1600

生长培养基:SH-SY5Y [SHSY-5Y] 细胞专用培养基

数量: - +

  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)

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SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确) ¥1600

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产品概述
产品信息
名称 SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
别称 SHSY5Y; SHSY-5Y; SH-Sy5y; SK-SH-SY5Y; SY5Y
种属
生长特性 贴壁细胞,极少量悬浮
细胞形态 上皮细胞样
冻存条件 冻存液:90%FBS+10%DMSO 温度:液氮
培养方案A(默认)
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
推荐传代比例 1:3-1:4
推荐换液频率 2-3次/周
注意事项 1.该细胞容易聚团,传代第二天轻微聚团甚至漂浮为正常现象,无需换液继续培养2~3天后细胞可正常贴壁;2.细胞聚团严重影响细胞生长后,可用胰酶消化细胞使之重新分散,传代后少动少换液,聚团会有改善。
参考资料(来源文献)
背景描述 SH-SY5Y细胞是于1970年建自骨瘤转移灶的神经母细胞瘤SK-N-SH细胞系经3次克隆后的亚系(SK-N-SH→SH-SY→SH-SY5→SH-SY5Y)。SH-SY5Y细胞显示中等水平的多巴胺-β-羟基酶活性,SH-SY5Y细胞的饱和密度大于1×10^6/cm^2。
年龄(性别) 女性;4岁
组织来源 脑神经母细胞瘤,转移部位骨髓
细胞类型 肿瘤细胞
肿瘤类型 神经母细胞瘤细胞
生物安全等级 BSL-1
倍增时间 ~48-72 hours
抗原表达情况 Blood Type A; Rh+
保藏机构 ATCC; CRL-2266 DSMZ; ACC-209 ECACC; 94030304
STR鉴定
  • STR位点信息
    Amelogenin X
    CSF1PO 11
    D2S1338 17,19
    D3S1358 15,16
    D5S818 12
    D7S820 7,10
    D8S1179 15
    D13S317 11
    D16S539 8,13
    D18S51 13,16
    D19S433 13,14
    D21S11 31,31.2
    FGA 23.2,24
    PentaD 10,12
    PentaE 7,11
    TH01 7,10
    TPOX 8,11
    vWA 14,18
    D6S1043 12,18
    D12S391 18,22
    D2S441 11,11.3
  • STR鉴定图
参考文献
文献列表
  • Exosome Heterogeneity Affects the Distal “Barrier-Crossing” Trafficking of Exosome Encapsulated Quantum Dots(2024/02/23)

    作者:Di Wu, Hang Sun, Bingwei Yang

    期刊:ACS Nano

    DOI:10.1021/acsnano.3c09378

    影响因子 :17.100

    引用产品:CL-0208

  • An artificial protein modulator reprogramming neuronal protein functions(2024/03/06)

    作者:Peihua Lin, Bo Zhang, Hongli Yang

    期刊:Nature Communications

    DOI:10.1038/s41467-024-46308-6

    影响因子 :16.600

    引用产品:CL-0208

  • A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease(2024/01/24)

    作者:Jiefei Wang, Shangguan Ping, Xiaoyu Chen

    期刊:Nature Communications

    DOI:10.1038/s41467-024-44737-x

    影响因子 :16.600

    引用产品:CL-0208

  • Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides(2022/08/06)

    作者:Zhanchi Zhu, Yuanxin Zhai, Ying Hao

    期刊:Journal of Extracellular Vesicles

    DOI:10.1002/jev2.12255

    影响因子 :16.000

    引用产品:CL-0005 CL-0016 CL-0103 CL-0208 CL-0238 CL-0598

  • SSK1-Loaded Neurotransmitter-Derived Nanoparticles for Alzheimers Disease Therapy via Clearance of Senescent Cells(2024/03/01)

    作者:Wenbo Ji, Honglei Zhou, Wendanqi Liang

    期刊:Small

    DOI:10.1002/smll.202308574

    影响因子 :13.300

    引用产品:CL-0208

  • Thioredoxin-1 inhibits the activation of IRE1 by targeting Hsp90/p-Cdc37 chaperone complex in Parkinson disease(2023/07/10)

    作者:Xiansi Zeng, Wenshuo Geng, Yu Zhang

    期刊:AGEING RESEARCH REVIEWS

    DOI:10.1016/j.arr.2023.102000

    影响因子 :13.100

    引用产品:CL-0208

  • Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimers disease by enhancing autophagy(2021/01/01)

    作者:Menglu Chen, Chungu Hong, Tao Yue

    期刊:Theranostics

    DOI:10.7150/thno.47408

    影响因子 :12.400

    引用产品:CL-0208

  • Bone marrow mesenchymal stem cells loaded into hydrogel/nanofiber composite scaffolds ameliorate ischemic brain injury(2023/01/28)

    作者:Yanhong Pei, Lifei Huang, Tong Wang

    期刊:Materials Today Advances

    DOI:10.1016/j.mtadv.2023.100349

    影响因子 :10.000

    引用产品:CL-0208 CM-0208 CM-0675

  • A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression(2024/02/27)

    作者:Yongrui Hai, Renming Fan, Ting Zhao

    期刊:PHARMACOLOGICAL RESEARCH

    DOI:10.1016/j.phrs.2024.107115

    影响因子 :9.300

    引用产品:CL-0208

  • MAPKAPK2, a potential dynamic network biomarker of α-synuclein prior to its aggregation in PD patients(2023/03/16)

    作者:Zhenggang Zhong, Jiabao Li, Jiayuan Zhong

    期刊:npj Parkinsons Disease

    DOI:10.1038/s41531-023-00479-z

    影响因子 :8.700

    引用产品:CL-0208

  • Controllable mitochondrial aggregation and fusion by a programmable DNA binder(2023/07/06)

    作者:Longyi Zhu, Yiting Shen, Shengyuan Deng

    期刊:Chemical Science

    DOI:10.1039/D2SC07095B

    影响因子 :8.400

    引用产品:CL-0007 CL-0208

  • Modified acid polysaccharide derived from Salvia przewalskii with excellent wound healing and enhanced bioactivity(2024/01/30)

    作者:Kui Zhao, Cheng Qian, Luming Qi

    期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

    DOI:10.1016/j.ijbiomac.2024.129803

    影响因子 :8.200

    引用产品:CL-0208

  • Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury(2024/04/26)

    作者:Shikang Zhou, Ziqi Wang, Ting Wang

    期刊:PHYTOMEDICINE

    DOI:10.1016/j.phymed.2024.155622

    影响因子 :7.900

    引用产品:CL-0208

  • NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells(2023/11/18)

    作者:Caixia Zhang, Bo Jiao, Xueqin Cao

    期刊:BIOMEDICINE & PHARMACOTHERAPY

    DOI:10.1016/j.biopha.2023.115889

    影响因子 :7.500

    引用产品:CL-0208

  • NIR-II light-activated two-photon squaric acid dye with Type I photodynamics for antitumor therapy(2022/10/24)

    作者:Kexin Wang, Yunjian Xu, Zhenjiang Chen

    期刊:Nanophotonics

    DOI:10.1515/nanoph-2022-0482

    影响因子 :7.500

    引用产品:CL-0208 PM150210

  • Nanosensor-Driven Detection of Neuron-Derived Exosomal Aβ42 with Graphene Electrolyte-Gated Transistor for Alzheimer’s Disease Diagnosis(2023/03/21)

    作者:Jiahao Li, Wei Ni, Dan Jin

    期刊:Analytical Chemistry

    DOI:10.1021/acs.analchem.2c05751

    影响因子 :7.400

    引用产品:CL-0208 CM-0208

  • Combined exposure to manganese and iron decreases oxidative stress-induced nerve damage by increasing Nrf2/HO-1/NQO1 expression(2023/12/20)

    作者:Yuanyuan Fang, Mengjun Teng, Jianchao Peng

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2023.115853

    影响因子 :6.800

    引用产品:CL-0208

  • Cyfluthrin exposure during pregnancy causes neurotoxicity in offspring—Ca2+ overload via IP3R-GRP75-VDAC1 pathway(2024/03/15)

    作者:Haoxuan Gao, Mi Tian, Xiaozhe Geng

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2024.116218

    影响因子 :6.800

    引用产品:CL-0208

  • Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells(2022/12/09)

    作者:CanCan Guo, Yi Lyu, ShuangShuang Xia

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2022.114350

    影响因子 :6.800

    引用产品:164210 164210-50 CL-0208 PM151220

  • LncRNA TUG1 compromised neuronal mitophagy in cerebral ischemia/reperfusion injury by targeting sirtuin 1(2022/03/28)

    作者:LongXing Xue, SongFeng Chen, Shi-Xing Xue

    期刊:Cell Biology And Toxicology

    DOI:10.1007/s10565-022-09700-w

    影响因子 :6.100

    引用产品:CL-0208

  • Exendin-4 and linagliptin attenuate neuroinflammation in a mouse model of Parkinson’s disease(2022/11/09)

    作者:Haiyang Yu, Tong Sun, Zhen Wang

    期刊:Neural Regeneration Research

    DOI:10.4103/1673-5374.360242

    影响因子 :6.058

    引用产品:CL-0208

  • Chebulic Acid Prevents Hypoxia Insult via Nrf2/ARE Pathway in Ischemic Stroke(2022/12/19)

    作者:Rong Zhou, Kuan Lin, Changlong Leng

    期刊:Nutrients

    DOI:10.3390/nu14245390

    影响因子 :5.900

    引用产品:CL-0208

  • Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop(2022/04/04)

    作者:Hengfang Tang, Zhiming Zheng, Han Wang

    期刊:Nutrients

    DOI:10.3390/nu14071504

    影响因子 :5.900

    引用产品:CL-0208

  • RVG29 Peptide-Modified Exosomes Loaded with Mir-133b Mediate the RhoA-ROCK Pathway to Improve Motor and Neurological Symptoms in Parkinson’s Disease(2024/04/05)

    作者:Peng Jiang, Yu Xiao, Xinmei Hu

    期刊:ACS Biomaterials Science & Engineering

    DOI:10.1021/acsbiomaterials.3c01622

    影响因子 :5.800

    引用产品:CL-0208

  • bub1 as a potential oncogene and a prognostic biomarker for neuroblastoma(2022/09/27)

    作者:Jingjing Song, Chao Ni, Xubin Dong

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2022.988415

    影响因子 :5.738

    引用产品:CL-0208

  • Chemical Hypoxia Induces Pyroptosis in Neuronal Cells by Caspase-Dependent Gasdermin Activation(2024/02/11)

    作者:Chan Ho Park, Jun Young Park, Won Gil Cho

    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

    DOI:10.3390/ijms25042185

    影响因子 :5.600

    引用产品:CL-0208

  • The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model(2023/02/13)

    作者:Ruru Jia, Yanling Liu, Ke Shuai

    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

    DOI:10.3390/ijms24043709

    影响因子 :5.600

    引用产品:CL-0208

  • α-Synuclein Induces Neuroinflammation Injury through the IL6ST-AS/STAT3/HIF-1α Axis(2023/01/11)

    作者:Danyu Lin, Han Zhang, Jieli Zhang

    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

    DOI:10.3390/ijms24021436

    影响因子 :5.600

    引用产品:CL-0208 CL-0620

  • Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer’s Disease Models(2024/03/17)

    作者:Ruonan Wang, Shijia Kang, Zirui Zhao

    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

    DOI:10.3390/ijms25063408

    影响因子 :5.600

    引用产品:CL-0208

  • Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development(2024/03/01)

    作者:Shuaiguang Li, Huarong Shao, Peixue Ling

    期刊:Frontiers in Pharmacology

    DOI:10.3389/fphar.2024.1366683

    影响因子 :5.600

    引用产品:CL-0208

  • HMGB3 is Associated With an Unfavorable Prognosis of Neuroblastoma and Promotes Tumor Progression by Mediating TPX2(2021/12/20)

    作者:Xiaodan Zhong, Songling Zhang

    期刊:Frontiers in Cell and Developmental Biology

    DOI:10.3389/fcell.2021.769547

    影响因子 :5.500

    引用产品:CL-0208 CL-0214 CL-0441

  • Huannao Yicong decoction ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by interfering with neurotoxic interaction of Aβ-tau(2023/08/01)

    作者:Huiqin Zhang, Wenxuan Chen, Zehui Li

    期刊:JOURNAL OF ETHNOPHARMACOLOGY

    DOI:10.1016/j.jep.2023.116985

    影响因子 :5.400

    引用产品:CL-0208

  • Fabrication of P and N Co-Doped Carbon Dots for Fe3+ Detection in Serum and Lysosomal Tracking in Living Cells(2023/02/05)

    作者:Yanzhi Xing, Mei Yang, Xuwei Chen

    期刊:Biosensors-Basel

    DOI:10.3390/bios13020230

    影响因子 :5.400

    引用产品:CL-0101 CL-0208

  • Neurotoxicity study of ethyl acetate extract of Zanthoxylum armatum DC. on SH-SY5Y based on ROS mediated mitochondrial apoptosis pathway(2023/10/20)

    作者:Jiafu Guo, Nannan Yang, Jian Zhang

    期刊:JOURNAL OF ETHNOPHARMACOLOGY

    DOI:10.1016/j.jep.2023.117321

    影响因子 :5.400

    引用产品:CL-0208

  • Cholestane-3β,5α,6β-triol Induces Multiple Cell Death in A549 Cells via ER Stress and Autophagy Activation(2024/04/13)

    作者:Jiaxi Chen, Jieping Zhang, Lijuan Cai

    期刊:Marine Drugs

    DOI:10.3390/md22040174

    影响因子 :5.400

    引用产品:CL-0208

  • Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells(2022/08/17)

    作者:Haiqun Dong, Shijing Liang, Yuling Xu

    期刊:International Journal of Oncology

    DOI:10.3892/ijo.2022.5409

    影响因子 :5.200

    引用产品:CL-0130 CL-0208

  • Novel flavonoid 1,3,4-oxadiazole derivatives ameliorate MPTP-induced Parkinsons disease via Nrf2/NF-κB signaling pathway(2023/06/03)

    作者:Huawen Meng, Zhenbao Shen, Xianshe Meng

    期刊:BIOORGANIC CHEMISTRY

    DOI:10.1016/j.bioorg.2023.106654

    影响因子 :5.100

    引用产品:CL-0208

  • Neuroprotective effect of chlorogenic acid on Parkinsons disease like symptoms through boosting the autophagy in zebrafish(2023/08/05)

    作者:Xin Gao, Baoyue Zhang, Yuanteng Zheng

    期刊:EUROPEAN JOURNAL OF PHARMACOLOGY

    DOI:10.1016/j.ejphar.2023.175950

    影响因子 :5.000

    引用产品:CL-0208

  • Novel Deoxyvasicinone–Donepezil Hybrids as Potential Multitarget Drug Candidates for Alzheimer’s Disease(2019/02/05)

    作者:Hongtao Du, Xinlian Liu, Jusen Xie

    期刊:ACS Chemical Neuroscience

    DOI:10.1021/acschemneuro.8b00699

    影响因子 :5.000

    引用产品:CL-0103 CL-0208

  • Silencing of long chain noncoding RNA paternally expressed gene (PEG10) inhibits the progression of neuroblastoma by regulating microRNA-449a (miR-449a)/ribosomal protein S2 (RPS2) axis(2022/02/25)

    作者:Jian Zhang, Wei Liu, Ping Ji

    期刊:Bioengineered

    DOI:10.1080/21655979.2022.2042999

    影响因子 :4.900

    引用产品:CL-0208 CL-0214 CL-0441 CL-0621 CP-H082

  • Effects of miRNAs in exosomes derived from α-synuclein overexpressing SH-SY5Y cells on autophagy and inflammation of microglia(2021/10/27)

    作者:Tianen Zhou, Meng Zhang, Yingyu Xie

    期刊:Cellular Signalling

    DOI:10.1016/j.cellsig.2021.110179

    影响因子 :4.800

    引用产品:CL-0208

  • CDC27-ODC1 Axis Promotes Metastasis, Accelerates Ferroptosis and Predicts Poor Prognosis in Neuroblastoma(2022/02/15)

    作者:Lin Qiu, Rui Zhou, Ziyan Luo

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2022.774458

    影响因子 :4.700

    引用产品:CL-0208 CL-0214

  • Libertellenone C attenuates oxidative stress and neuroinflammation with the capacity of NLRP3 inhibition(2024/02/26)

    作者:Jie Cao, Lanqin Li, Runge Zhang

    期刊:Natural Products and Bioprospecting

    DOI:10.1007/s13659-024-00438-y

    影响因子 :4.700

    引用产品:CL-0208

  • Identifying the potential genes in alpha synuclein driving ferroptosis of Parkinson’s disease(2023/10/06)

    作者:Min Wang, Taole Li, Rong Gao

    期刊:Scientific Reports

    DOI:10.1038/s41598-023-44124-4

    影响因子 :4.600

    引用产品:CL-0208

  • VCAM-1+ hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis(2023/06/19)

    作者:Xiao Zhang, Xiaoyu Sang, Yanting Chen

    期刊:NEUROCHEMICAL RESEARCH

    DOI:10.1007/s11064-023-03968-y

    影响因子 :4.400

    引用产品:CL-0208 PM151220

  • The protective effects of Agomelatine against Aβ1-42 oligomers-induced cellular senescence mediated by SIRT6 and Agomelatine’s potential in AD treatment(2021/09/17)

    作者:Jian Wang, Bo Zheng, Shu Yang

    期刊:Human Cell

    DOI:10.1007/s13577-021-00611-2

    影响因子 :4.374

    引用产品:CL-0208

  • Potential Cause-and-Effect Relationship between Gut Microbiota and Childhood Neuroblastoma: A Mendelian Randomization Analysis(2024/03/27)

    作者:Jing Chu

    期刊:INDIAN JOURNAL OF PEDIATRICS

    DOI:10.1007/s12098-024-05065-6

    影响因子 :4.300

    引用产品:CL-0208

  • STAT4 targets KISS1 to inhibit the oxidative damage, inflammation and neuronal apoptosis in experimental PD models by inactivating the MAPK pathway(2024/02/08)

    作者:XiaoLei Zhang, Yu Wang, Jia Lv

    期刊:NEUROCHEMISTRY INTERNATIONAL

    DOI:10.1016/j.neuint.2024.105683

    影响因子 :4.200

    引用产品:CL-0208

  • Exploring the Therapeutic Effects of Multifunctional N-Salicylic Acid Tryptamine Derivative against Parkinson’s Disease(2023/07/28)

    作者:Xuelin Li, Shuzhi Wang, Shan Duan

    期刊:ACS Omega

    DOI:10.1021/acsomega.3c04277

    影响因子 :4.100

    引用产品:CL-0208 CL-0620

  • EIF5A2 specifically regulates the transcription of aging-related genes in human neuroblastoma cells(2023/02/07)

    作者:Yuwei Liu, Li Peng, Jing Chen

    期刊:BMC Geriatrics

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