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人脐静脉内皮细胞
Human Umbilical Vein Endothelial Cells
货号:CP-H082
规格:5×10⁵Cells/T25培养瓶
价格: ¥6380
培养基货号: CM-H082
产品概述
人脐静脉内皮细胞
Cat NO.: CP-H082
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产品名称:人脐静脉内皮细胞
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英文简称:UVECs
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组织来源:脐带组织
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产品规格:5×105cells/T25细胞培养瓶
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细胞简介:
人脐静脉内皮细胞分离自脐带组织;它是脐静脉的重要结构组成细胞之一,在机体的正常生理过程中发挥着重要作用。脐带是哺乳类的连接胎儿和胎盘的管状结构,脐带中通过尿膜的血管即脐动脉和脐静脉,卵黄囊的血管即脐肠系膜动脉及脐肠系膜静脉。在子宫中,子宫动脉在胎盘的母体部分出的毛细血管,与胎盘的子体部胎儿毛细血管靠近,在此处母体和胎儿的血液间进行CO2和O2,代谢产物即代谢废物和营养物质的交换。脐动脉将胎儿产生的废物运送至胎盘,脐静脉将O2和营养物质从胎盘运送给胎儿。
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方法简介:
普诺赛实验室分离的人脐静脉内皮细胞采用胰蛋白酶-胶原酶联合消化法结合差速贴壁法、并通过内皮细胞专用培养基培养筛选制备而来,细胞总量约为5×10⁵cells/瓶。
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质量检测:
普诺赛实验室分离的人脐静脉内皮细胞经CD31免疫荧光鉴定,纯度可达90%以上,且不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌等。
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培养信息:
包被条件 PLL(0.1mg/ml),明胶(0.1%) 培养基 含FBS、生长添加剂、Penicillin、Streptomycin等 产品货号 CM-H082 换液频率 每2-3天换液一次 生长特性 贴壁 细胞形态 内皮细胞样 传代特性 可传3-5代左右;3代以内状态最佳 消化液 0.25%胰蛋白酶 培养条件 气相:空气,95%;CO2,5% 人脐静脉内皮细胞体外培养周期有限;建议使用普诺赛配套的专用生长培养基及正确的操作方法来培养,以此保证该细胞的最佳培养状态。
产品手册
参考文献
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DOI:10.3389/fbioe.2023.1098172
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DOI:10.3389/fbioe.2023.1168750
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Transendothelial electrical resistance measurement by a microfluidic device for functional study of endothelial barriers in inflammatory bowel disease(2023/07/14)
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期刊:Frontiers in Bioengineering and Biotechnology
DOI:10.3389/fbioe.2023.1236610
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Hydrogen sulfide regulates macrophage polarization and necroptosis to accelerate diabetic skin wound healing(2024/04/03)
作者:Ziying He, Yue Zhu, Haojie Ma
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2024.111990
影响因子 :5.600
引用产品:CP-H082
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iNOS inhibitor S-methylisothiourea alleviates smoke inhalation-induced acute lung injury by suppressing inflammation and macrophage infiltration(2023/11/20)
作者:Yinghan Shi, Yan Cao, Xinjie Han
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.111097
影响因子 :5.600
引用产品:CP-H082
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TRPC6 Deletion Enhances eNOS Expression and Reduces LPS—Induced Acute Lung Injury(2023/11/25)
作者:Mengyuan Wang, Xingfang Zhang, Juan Guo
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :5.600
引用产品:CP-H082
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Sialic acids promote macrophage M1 polarization and atherosclerosis by upregulating ROS and autophagy blockage(2023/06/03)
作者:Xuemei Hu, Yueyue Li, Qingyang Chen
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.110410
影响因子 :5.600
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LncRNA SNHG15 relieves hyperglycemia-induced endothelial dysfunction via increased ubiquitination of thioredoxin-interacting protein(2021/06/08)
作者:Qianqian Zhu, Mingchun Lai, Tianchi Chen
期刊:Laboratory Investigation
DOI:10.1038/s41374-021-00614-5
影响因子 :5.502
引用产品:CP-H082
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Functionalized Periodic Mesoporous Silica Nanoparticles for Inhibiting the Progression of Atherosclerosis by Targeting Low-Density Lipoprotein Cholesterol(2024/01/04)
作者:Hao Jin, Wenbin Lu, Yahao Zhang
期刊:Pharmaceutics
DOI:10.3390/pharmaceutics16010074
影响因子 :5.400
引用产品:CP-H082
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Epidermal Growth Factor‐Like Repeats and Discoidin I‐Like Domains 3 Deficiency Attenuates Dilated Cardiomyopathy by Inhibiting Ubiquitin Specific Peptidase 10 Dependent Smad4 Deubiquitination(2024/03/08)
作者:Mengmeng Zhao, Zihui Zheng, Shanshan Peng
期刊:Journal of the American Heart Association
影响因子 :5.400
引用产品:CP-H082
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Non-Invasive and Label-Free On-Chip Impedance Monitoring of Heatstroke(2023/06/27)
作者:Yueli Zhao, Weihua Fan, Anwei Liu
期刊:Biosensors-Basel
影响因子 :5.400
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Macrophage-derived exosomal miR-4532 promotes endothelial cells injury by targeting SP1 and NF-κB P65 signalling activation(2022/09/07)
作者:Peng Liu, Shuya Wang, Guangxin Wang
期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 :5.300
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Asiaticoside Attenuates Blood–Spinal Cord Barrier Disruption by Inhibiting Endoplasmic Reticulum Stress in Pericytes After Spinal Cord Injury(2023/09/01)
作者:Zhenxin Hu, Tingting Wu, Ziheng Zhou
期刊:MOLECULAR NEUROBIOLOGY
DOI:10.1007/s12035-023-03605-3
影响因子 :5.100
引用产品:CP-H082
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Silencing of long chain noncoding RNA paternally expressed gene (PEG10) inhibits the progression of neuroblastoma by regulating microRNA-449a (miR-449a)/ribosomal protein S2 (RPS2) axis(2022/02/25)
作者:Jian Zhang, Wei Liu, Ping Ji
期刊:Bioengineered
DOI:10.1080/21655979.2022.2042999
影响因子 :4.900
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Nano−/micro-scaled hydroxyapatite ceramic construction and the regulation of immune-associated osteogenic differentiation(2023/09/08)
作者:Shijia Fu, Huishan Li, Yue Wu
期刊:JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
影响因子 :4.900
引用产品:CP-H082
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MicroRNA-140-3p represses the proliferation, migration, invasion and angiogenesis of lung adenocarcinoma cells via targeting TYMS (thymidylate synthetase)(2021/12/16)
作者:Shanzhi Wan, Zhimin Liu, Yang Chen
期刊:Bioengineered
DOI:10.1080/21655979.2021.2009422
影响因子 :4.900
引用产品:CP-H082
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Endothelial CYP2J2 overexpression restores the BRB via METTL3-mediated ANXA1 upregulation(2022/10/21)
作者:Bowen Zhao, Jingqiu Huang, Xiaotong Lou
期刊:FASEB JOURNAL
影响因子 :4.800
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An Autophagy-Associated MITF–GAS5–miR-23 Loop Attenuates Vascular Oxidative and Inflammatory Damage in Sepsis(2023/06/24)
作者:Junning Cheng, Chang Ding, Huying Tang
期刊:Biomedicines
DOI:10.3390/biomedicines11071811
影响因子 :4.700
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Composite Hydrogel Containting Collagen-Modified Polylactic Acid-hydroxylactic acid Copolymer Microspheres Loaded with Tetramethylpyrazine Promotes Articular Cartilage Repair(2024/04/10)
作者:Yalan Pan, Bin Li, Xiaoxian Sun
期刊:MACROMOLECULAR BIOSCIENCE
影响因子 :4.600
引用产品:CP-H082
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Microfluidics-Based Fabrication of Cell-Laden Hydrogel Microfibers for Potential Applications in Tissue Engineering(2019/04/25)
作者:Gen Wang, Luanluan Jia, Fengxuan Han
期刊:Molecules
影响因子 :4.600
引用产品:CP-H082
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Butylated hydroxyanisole induces vascular endothelial injury via TFEB-mediated degradation of GPX4 and FTH1(2024/04/22)
作者:Yufei Zhan, Yazhuo Zhang
期刊:FOOD AND CHEMICAL TOXICOLOGY
影响因子 :4.300
引用产品:CP-H082
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LncRNA FGF7-5 and lncRNA GLRX3 together inhibits the formation of carotid plaque via regulating the miR-2681-5p/ERCC4 axis in atherosclerosis(2022/09/07)
作者:Jianjin Wu, Jie Jin, Yonghua Li
期刊:CELL CYCLE
DOI:10.1080/15384101.2022.2110446
影响因子 :4.300
引用产品:CP-H082
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MicroRNA-9 rescues hyperglycemia-induced endothelial cell dysfunction and promotes arteriogenesis through downregulating Notch1 signaling(2021/3/15)
作者:Huang Chen, Zhihai Feng, Lieyou Li
期刊:Molecular And Cellular Biochemistry
DOI:10.1007/s11010-021-04075-8
影响因子 :4.300
引用产品:CP-H082
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Polyethylenimine Triggers Dll4 Degradation to Regulate Angiogenesis In Vitro(2024/02/07)
作者:Binghua Cheng, Yanyan Li, Yabin Ji
期刊:ACS Omega
影响因子 :4.100
引用产品:CP-H082
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ADAR1 is targeted by miR-143 to regulate IL-1β-induced endothelial activation through the NFκB pathway(2017/5/17)
作者:Yuanzhuo Chen, Hu Peng, Shuqin Zhou
期刊:International Journal Of Biochemistry & Cell Biology
DOI:10.1016/j.biocel.2017.05.021
影响因子 :4.000
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Exosome-derived miR-23a-5p inhibits HCC proliferation and angiogenesis by regulating PRDX2 expression: MiR-23a-5p/PRDX2 axis in HCC progression.(2023/12/02)
作者:Yang Zhao, Jun Liu, Zhengping Xiong
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e23168
影响因子 :4.000
引用产品:CP-H082
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M2 macrophage-derived exosomes induce angiogenesis and increase skin flap survival through HIF1AN/HIF-1α/VEGFA control(2023/11/27)
作者:Gaojie Luo, Zekun Zhou, Zheming Cao
期刊:ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影响因子 :3.900
引用产品:CP-H082
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Interfering with Dusp2 alleviates high glucose-induced vascular endothelial cell dysfunction by promoting p38 MAPK pathway activation(2023/07/20)
作者:Xinmiao Jiang, Qiong Yan, Jiaqi He
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2023.113720
影响因子 :3.700
引用产品:CP-H082
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DNMT3A-mediated epigenetic silencing of SOX17 contributes to endothelial cell migration and fibroblast activation in wound healing(2023/10/19)
作者:Xiaoping Yu, Xiaoting Ma, Junli Zhou
期刊:PLoS One
DOI:10.1371/journal.pone.0292684
影响因子 :3.700
引用产品:CP-H082
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PCSK9 inhibitor inclisiran for treating atherosclerosis via regulation of endothelial cell pyroptosis(2022/11/01)
作者:Ni Kong, Qin Xu, Wei Cui
期刊:Annals of Translational Medicine
影响因子 :3.616
引用产品:CP-H082
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Curcumin suppresses the malignant phenotype of laryngeal squamous cell carcinoma through downregulating E2F1 to inhibit FLNA(2024/04/09)
作者:Yuanchun Xie, Jingjing Qi, Ju Liu
期刊:NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI:10.1007/s00210-024-03059-x
影响因子 :3.600
引用产品:CP-H082
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Reduction of renal interstitial fibrosis by targeting Tie2 in vascular endothelial cells(2023/11/27)
作者:Lu Jiang, Xiaohan Hu, Yajun Feng
期刊:PEDIATRIC RESEARCH
DOI:10.1038/s41390-023-02893-8
影响因子 :3.600
引用产品:CP-H082
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Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway(2024/01/12)
作者:Dong Yuan, Zhipeng Zheng, Cheng Shen
期刊:MOLECULAR IMMUNOLOGY
DOI:10.1016/j.molimm.2024.01.002
影响因子 :3.600
引用产品:CP-H082
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Synergistic anti-tumour activity of ginsenoside Rg3 and doxorubicin on proliferation, metastasis and angiogenesis in osteosarcoma by modulating mTOR/HIF-1α/VEGF and EMT signalling pathways(2023/07/27)
作者:Xiangfeng Zeng, Shengyao Liu, Hua Yang
期刊:JOURNAL OF PHARMACY AND PHARMACOLOGY
影响因子 :3.300
引用产品:CP-H082
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Regulation of Atherosclerosis by Toll-Like Receptor 4 Induced by Serum Amyloid 1: A Systematic In Vitro Study.(2022/09/15)
作者:Jinhui Chen, Gang Liu, Yan Hong
期刊:Biomed Research International
影响因子 :3.246
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Melatonin inhibits the formation of intraplaque neovessels in ApoE−/− mice via PPARγ- RhoA-ROCK pathway(2023/12/28)
作者:YuFan Jiang, Wei Tong, Yueyang Li
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.149391
影响因子 :3.100
引用产品:CP-H082
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Bioactive self-healing umbilical cord blood exosomes hydrogel for promoting chronic diabetic wound healing(2023/11/11)
作者:Kexin Liu, Benxin Gong, Tao Li
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.149241
影响因子 :3.100
引用产品:CP-H082
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Dulaglutide restores endothelial progenitor cell levels in diabetic mice and mitigates high glucose-induced endothelial injury through SIRT1-mediated mitochondrial fission(2024/04/25)
作者:Xi Mei, Yao Li, Jinlin Wu
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2024.150002
影响因子 :3.100
引用产品:CP-H082
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Quercetin alleviates hyperoxia-induced bronchopulmonary dysplasia by inhibiting ferroptosis through the MAPK/PTGS2 pathway: Insights from network pharmacology, molecular docking, and experimental evaluations(2024/04/03)
作者:Xianhui Deng, Dan Chen, Anni Xie
期刊:Chemical Biology & Drug Design
影响因子 :3.000
引用产品:CP-H082
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Flavonoid Compounds in Hippophae rhamnoides L. Protect Endothelial Cells from Oxidative Damage Through the PI3K/AKT-eNOS Pathway(2024/03/02)
作者:Mengyuan Wang, Xingfang Zhang, Zonghao Zhang
期刊:CHEMISTRY & BIODIVERSITY
影响因子 :2.900
引用产品:CP-H082
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Interleukin‑6 released by oral lichen planus myofibroblasts promotes angiogenesis(2021/01/27)
作者:Xiaoheng Xu, Yang Liu, Lu Feng
期刊:Experimental and Therapeutic Medicine
影响因子 :2.700
引用产品:CP-H082
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DNTTIP2 Expression is Associated with Macrophage Infiltration and Malignant Characteristics in Low-Grade Glioma(2022/11/19)
作者:Yuanjie Liu, Shuhong Zeng, Weihua Qian
期刊:Pharmacogenomics & Personalized Medicine
影响因子 :2.606
引用产品:CP-H082
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Gastrodin Suppresses the Progression of Atherosclerosis and Vascular Inflammation by Regulating TLR4/NF‐κB Pathway(2024/01/25)
作者:Bing Dai, Cunfa Liu, Song Zhang
期刊:CELL BIOCHEMISTRY AND BIOPHYSICS
DOI:10.1007/s12013-024-01218-8
影响因子 :2.600
引用产品:CP-H082
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Exploring the application of sildenafil for high-fat diet-induced erectile dysfunction based on interleukin-18-mediated NLRP3/Caspase-1 signaling pathway(2023/08/25)
作者:Bingbing Zhu, Yangjiu Niu, Lipan Niu
期刊:Sexual Medicine
影响因子 :2.600
引用产品:CP-H082
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Circular RNA (circ)_0053277 Contributes to Colorectal Cancer Cell Growth, Angiogenesis, Metastasis and Glycolysis(2023/11/02)
作者:Jianbin Zhuang, Weiliang Song, Minghao Li
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-023-00936-3
影响因子 :2.600
引用产品:CP-H082
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Curcumin Inhibits the Progression of Non-small Cell Lung Cancer by Regulating DMRT3/SLC7A11 Axis(2024/05/14)
作者:Bin Xu, Li Zhou, Qian Zhang
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-024-01166-x
影响因子 :2.600
引用产品:CP-H082
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NREP is a Diagnostic and Prognostic Biomarker, and Promotes Gastric Cancer Cell Proliferation and Angiogenesis(2022/09/12)
作者:Qian Li, Lei Fu, Daoyuan Wu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10276-7
影响因子 :2.400
-
Circular RNA circCHSY1 silencing inhibits the malignant progression of esophageal squamous cell carcinoma(2024/03/21)
作者:Haiquan He, Ying Chen, Hanping Liang
期刊:Discover Oncology
DOI:10.1007/s12672-024-00935-z
影响因子 :2.200
引用产品:CP-H082
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Hsa_circ_0048674 facilitates hepatocellular carcinoma progression and natural killer cell exhaustion depending on the regulation of miR-223-3p/PDL1(2022/12/01)
作者:Suihui Li, Zhuangzhong Chen, Ruisheng Zhou
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.130
引用产品:CP-H082
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Knockdown of circ_0004585 enhances the chemosensitivity of colorectal cancer cells to 5-fluorouracil via the miR-874-3p/CCND1 axis(2023/01/01)
作者:Shijie Wang, Juan Cao, Lijuan Pei
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.000
引用产品:CP-H082
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Kelp Fucoidans Facilitate Vascular Recanalization via Inhibiting Excessive Activation of Platelet in Deep Venous Thrombosis Model of Mouse(2024/04/01)
作者:Taohua Sun, Jie Liu, Taishan Yan
期刊:Journal of Ocean University of China
影响因子 :1.600
引用产品:CP-H082
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The effects of propranolol on the biology and Notch signaling pathway of human umbilical vein endothelial cells(2023/08/11)
作者:Shuming Chen, Xuekai Zhao, Junjie Huang
期刊:MEDICINE
DOI:10.1097/MD.0000000000034672
影响因子 :1.600
引用产品:CP-H082
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Comparative Analysis of the Anti-Inflammatory Effects of Liraglutide and Dulaglutide(2024/05/15)
作者:Yi Hou, Yini Fan, Yuan Cheng
期刊:International Heart Journal
影响因子 :1.500
引用产品:CP-H082
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Fabrication of co-polymeric nanoformulation loaded with antibiotic ofloxacin and immunosuppressant tacrolimus for pediatric sepsis-induced acute lung injury(2023/07/01)
作者:Shuang Yuan, Dai Qian, Wanyun Su
期刊:Materials Express
影响因子 :0.700
引用产品:CP-H082
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