产品中心Cell Resources
联系我们CONTACT US
- 400-999-210024小时服务热线
产品概述
名称 | CT26.WT (小鼠结肠癌细胞) (STR鉴定正确) |
别称 | CT26WT |
种属 | 小鼠 |
生长特性 | 贴壁细胞 |
细胞形态 | 成纤维细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | CT26细胞是以N-亚硝基-N-甲基氨基甲酸酯(NNMU)诱导形成的未分化结肠癌细胞株,它克隆形成的细胞株命名为CT26.WT。用包含编码典型肿瘤相关抗原(TAA)β-半乳糖苷酶(β-gal)的lacZ基因的逆转录病毒载体LXSN稳定转染CT26.WT细胞,得到致死的亚克隆CT26.CL25。即使CT26.CL25细胞表达了典型的TAA-β-半乳糖苷酶,在正常小鼠中CT26.CL25细胞和CT26.WT细胞的生长率与致死率也保持基本一致。CT26.WT细胞与CT26.CL25细胞一起可用作测试免疫治疗程序的模型,并用于研究宿主免疫反应。 |
年龄(性别) | 不详 |
组织来源 | 器官:结肠;品系:BALB/c;疾病:癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肠癌细胞 |
生物安全等级 | BSL-1 |
致瘤性 | Yes, in BALB/c mice. Mice inoculated, subcutaneously, developed lethal tumors at 80% frequency with 1×10^3 cells and at 100% with 1×10^4 cells. Pulmonary metastases developed when mice were inoculated, intravenously, with 1×10^4 cells. |
抗原表达情况 | H-2d |
保藏机构 | ATCC; CRL-2638 BCRC; 60447 |
STR鉴定
-
STR位点信息
18-3 19,20 6-7 12 5-5 14 X-1 25,26 1-2 17,18 7-1 25.2 8-1 13 1-1 14,15 19-2 13 15-3 21.3,22.3 12-1 16,17 6-4 18,20 4-2 21.3 3-2 14 2-1 16,17 13-1 16.2,17.2,18.2
11-2 17 17-2 15,16,17 -
STR鉴定图
参考文献
-
Oxyhaemoglobin saturation NIR-IIb imaging for assessing cancer metabolism and predicting the response to immunotherapy(2023/09/11)
作者:Zhiguo Fang, Chenlei Wang, Jingrun Yang
期刊:Nature Nanotechnology
DOI:10.1038/s41565-023-01501-4
影响因子 :38.300
引用产品:CL-0071
-
Generation of whole tumor cell vaccine for on-demand manipulation of immune responses against cancer under near-infrared laser irradiation(2023/07/26)
作者:Jiaqi Meng, Yanlin Lv, Weier Bao
期刊:Nature Communications
DOI:10.1038/s41467-023-40207-y
影响因子 :16.600
-
Microbubbles-assisted ultrasonication to promote tumor accumulation of therapeutics and modulation of tumor microenvironment for enhanced cancer treatments(2023/06/01)
作者:Ju Huang, Liang Zhang, Jun Zheng
期刊:BIOMATERIALS
DOI:10.1016/j.biomaterials.2023.122181
影响因子 :14.000
-
Nitroreductase-instructed supramolecular assemblies for microbiome regulation to enhance colorectal cancer treatments(2022/11/09)
作者:Jiali Chen, Pai Zhang, Yan Zhao, Jie Zhao, Xiaobo Wu, Ruijia Zhang, Ruitao Cha, Qingxin Yao, Yuan Gao
期刊:Science Advances
影响因子 :13.600
引用产品:CL-0071 CL-0096 CL-0101 CL-0118 PM150110 PM150210 PM150710
-
Drug-loaded microbubble delivery system to enhance PD-L1 blockade immunotherapy with remodeling immune microenvironment(2023/02/09)
作者:Jun Zheng, Ju Huang, Liang Zhang
期刊:Biomaterials Research
DOI:10.1186/s40824-023-00350-5
影响因子 :11.300
-
Original research: Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer(2023/08/18)
作者:Yibo Quan, Jie He, Qi Zou
期刊:Journal for ImmunoTherapy of Cancer
影响因子 :10.900
引用产品:CL-0071
-
Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner(2023/02/03)
作者:Yiru Long, Runqiu Chen, Xiaolu Yu
期刊:Cancer Immunology Research
DOI:10.1158/2326-6066.CIR-22-0439
影响因子 :10.100
引用产品:CL-0005 CL-0007 CL-0019 CL-0071 CL-0105 CL-0129 CL-0140 CL-0196 CL-0246 CL-0319
-
Targeted Clearance of Senescent Cells Via Engineered Extracellular Vesicles Reprograms Tumor Immunosuppressive Microenvironment(2024/05/24)
作者:Panpan Ji, Chen Wang, Yang Liu
期刊:Advanced Healthcare Materials
影响因子 :10.000
引用产品:CL-0071
-
Dynamic shielding of bacterial outer membrane vesicles for safe and efficient chemo-immunotherapy against tumors(2023/11/17)
作者:Shuping Li, Xin Li, Jiaqi Meng
期刊:Nano Research
影响因子 :9.900
引用产品:CL-0071
-
Aggregation-Induced Emission Photosensitizer/Bacteria Biohybrids Enhance Cerenkov Radiation-Induced Photodynamic Therapy by Activating Anti-Tumor Immunity for Synergistic Tumor Treatment(2023/06/15)
作者:Ziyang Zhu, Qingyao Liu, Ke Zhu
期刊:Acta Biomaterialia
DOI:10.1016/j.actbio.2023.06.009
影响因子 :9.700
引用产品:CL-0071
-
CXCL1/IGHG1 signaling enhances crosstalk between tumor cells and tumor-associated macrophages to promote MC-LR-induced colorectal cancer progression(2024/04/30)
作者:Lingqiao Wang, Weiyan Chen, Huidong Jin
期刊:ENVIRONMENTAL POLLUTION
DOI:10.1016/j.envpol.2024.124081
影响因子 :8.900
引用产品:CL-0071
-
Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis(2024/05/27)
作者:Zhixin Ma, Yu Sun, Yang Yu
期刊:Cell Communication and Signaling
DOI:10.1186/s12964-024-01669-9
影响因子 :8.400
引用产品:CL-0071
-
A hybrid of lactic acid bacteria and metal-organic frameworks potentiates photodynamic immunotherapy for hypoxia-targeted tumor eradication(2022/08/12)
作者:Tianzhong Li, Jinyong Wang, Tongkai Chen
期刊:Science China-Materials
影响因子 :8.100
-
Smart Nanosystem-Mediated Inhibition of Mitochondrial Respiration for Enhanced Phototherapy-Induced Antitumor Immunity(2023/06/25)
作者:Yifan Zhao, Bai Lv, Guanghe Xue
期刊:International Journal of Nanomedicine
影响因子 :8.000
-
Dual-inhibition of lactate metabolism and Prussian blue-mediated radicals generation for enhanced chemodynamic therapy and antimetastatic effect(2023/04/18)
作者:Wenting Li, Shikai Liu, Yangyang Zhang
期刊:Nanoscale
影响因子 :6.700
-
A tungsten nitride-based degradable nanoplatform for dual-modal image-guided combinatorial chemo-photothermal therapy of tumors(2018/12/27)
作者:Cheng Zhang,Shibo Wang,Zhaoxia Chen
期刊:Nanoscale
影响因子 :6.700
-
Bifunctional liposomes reduce the chemotherapy resistance of doxorubicin induced by reactive oxygen species(2019/08/15)
作者:Lei Xu, Zhicheng Zhang, Yawen Ding
期刊:Biomaterials Science
影响因子 :6.600
引用产品:CL-0071
-
Long noncoding RNA Gm31629 protects against mucosal damage in experimental colitis via YB-1/E2F pathway(2022/03/22)
作者:Xu Feng, Ye Xiao, Jian He
期刊:mBio
DOI:10.1172/jci.insight.150091
影响因子 :6.500
引用产品:CL-0071
-
Tumor-targeting engineered probiotic Escherichia coli Nissle 1917 inhibits colorectal tumorigenesis and modulates gut microbiota homeostasis in mice(2023/04/24)
作者:Haibo Tang, Tuoyu Zhou, Weilin Jin
期刊:Life Sciences
影响因子 :6.100
引用产品:CL-0071
-
CAR-T-Cell Therapy for Solid Tumors Positive for Fibronectin Extra Domain B(2022/09/14)
作者:Zhijie Zhang, Chang Liu, Zhe Yang
期刊:Cells
影响因子 :6.000
-
Ansofaxine hydrochloride inhibits tumor growth and enhances Anti-TNFR2 in murine colon cancer model(2023/12/14)
作者:Qianyu Jing, Quan Wan, Yujie Nie
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2023.1286061
影响因子 :5.600
引用产品:CL-0071
-
TP53TG1/STAT axis is involved in the development of colon cancer through affecting PD-L1 expression and immune escape mechanism of tumor cells(2023/11/15)
作者:Wenmin Ji, Wenyan Wang, Yanfang Wei
期刊:American Journal of Cancer Research
DOI:PMID:38058799
影响因子 :5.300
引用产品:CL-0071
-
Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer(2020/01/03)
作者:Man Hu, Zhaomin Yu, Peiyuan Mei
期刊:Aging-US
影响因子 :5.200
-
Gut Microbiome Influences the Efficacy of PD-1 Antibody Immunotherapy on MSS-Type Colorectal Cancer via Metabolic Pathway(2020/4/30)
作者:Xu Xinjian, Lv Ji, Guo Fang
期刊:Frontiers in Microbiology
影响因子 :5.200
引用产品:CL-0071
-
Excessive consumption of mucin by over-colonized Akkermansia muciniphila promotes intestinal barrier damage during malignant intestinal environment(2023/03/02)
作者:Shuang Qu, Yinghui Zheng, Yichun Huang
期刊:Frontiers in Microbiology
DOI:10.3389/fmicb.2023.1111911
影响因子 :5.200
引用产品:CL-0071
-
Self-Assembled Amphiphilic Camptothecin Nanoparticles with Glutathione-Responsive and Tumor-Targeting Ability for Enhanced Colorectal Cancer Therapy(2023/09/21)
作者:XiaoJie Song, Kangli Lan, Yifei Xue
期刊:Advanced Therapeutics
影响因子 :4.600
引用产品:CL-0071
-
Ferulic Acid Induces Autophagy and Apoptosis in Colon Cancer CT26 Cells via the MAPK Pathway(2023/08/11)
作者:Shanbin Chen, Dong Zhao, Chunguang Luan
期刊:MOLECULES
影响因子 :4.600
引用产品:CL-0071
-
The Impact of Atmospheric Cadmium Exposure on Colon Cancer and the Invasiveness of Intestinal Stents in the Cancerous Colon(2024/03/14)
作者:Shuai Zhang, Ruikang Li, Jing Xu
期刊:Toxics
影响因子 :4.600
引用产品:CL-0071
-
Arrangement of Indocyanine Green in a 1.5-Nanometer Channel to Achieve High-Efficiency Imaging of the Intestinal Lymphatic System(2022/12/08)
作者:Xiangyi Kong, Nan Gao, Jianshi Du
期刊:MOLECULES
影响因子 :4.600
-
Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway(2023/12/27)
作者:Fenglin Luo, Yimeng Tang, Lin Zheng
期刊:Pharmaceuticals
影响因子 :4.600
引用产品:CL-0071
-
Danggui Buxue Decoction in the Treatment of Metastatic Colon Cancer: Network Pharmacology Analysis and Experimental Validation(2022/09/30)
作者:Shihan Feng, Bin Zhao, Xue Zhan
期刊:Drug Design Development and Therapy
影响因子 :4.319
引用产品:CL-0071
-
Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression(2023/03/22)
作者:Yu Sun, Wenjun Xiao, Yang Yu
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2023.113565
影响因子 :3.700
引用产品:CL-0071
-
A serum metabolomics study based on LC-MS: Chemosensitization effects of Rauvolfia vomitoria Afzel. combined with 5- fluorouracil on colorectal cancer mice(2022/09/22)
作者:Zhifan Wang, Wenru Kong, Ning Wang
期刊:JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
DOI:10.1016/j.jpba.2022.115074
影响因子 :3.400
引用产品:CL-0071
-
Disulfiram-loaded hollow copper sulfide nanoparticles show anti-tumor effects in preclinical models of colorectal cancer(2022/10/07)
作者:Zeyidan Jiapaer, Lingying Zhang, Wanli Ma
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2022.10.027
影响因子 :3.100
引用产品:CL-0071
-
Astaxanthin Ameliorates Skeletal Muscle Atrophy in Mice With Cancer Cachexia(2024/04/03)
作者:Xinyue Yu, Pengfei Ren, Ruzhen Yang
期刊:NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
DOI:10.1080/01635581.2024.2335584
影响因子 :2.900
引用产品:CL-0071
-
MiR-26a-5p exerts its influence by targeting EP300, a molecule known for its role in activating the PI3K/AKT/mTOR signaling pathway in CD8+tumor-infiltrating lymphocytes of colorectal cancer(2023/11/30)
作者:Chao Wang, Haonan Lin, Wangqiang Zhao
期刊:CELLULAR AND MOLECULAR BIOLOGY
DOI:10.14715/cmb/2023.69.12.37
影响因子 :1.600
引用产品:CL-0071
-
GSH-Responsive Dnase-I-Loaded MnOx Nanoplatforms for Combined Protein-Chemodynamic Therapy(2022/12/29)
作者:Zhongsheng Xu, Liang Zhang, Tao Sun
期刊:Advanced NanoBiomed Research
影响因子 :0.000
引用产品:CL-0071
FAQs
Q:{{item.question}}
A:
产品资料
识别码示意图