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产品概述
产品信息
| 别名 | Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2 |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Ala21-Thr153 |
| 检索号 | P60568 |
| 分子量 | 16.4 kDa |
| 表观分子量 | 14-18 kDa |
| 标签 | C-6His |
| 生物活性 | Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells The specific activity of Recombinant Human IL-2 is ≥1×10^7 IU/mg. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | <1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 运输 | Ambient temperature or ice pack. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH 7.4. |
| 复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled waterPlease aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介绍
Interleukin-2 (IL-2) is an Interleukin, a type of Cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/ IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
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