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产品概述
产品信息
| 别名 | Interleukin-9; IL-9; Cytokine P40; T-Cell Growth Factor P40; IL9 |
| 物种 | Mouse |
| 表达宿主 | Human Cells |
| 序列信息 | Gln19-Pro144 |
| 检索号 | P15247 |
| 分子量 | 15.2 kDa |
| 表观分子量 | 28-42 kDa |
| 标签 | C-6His |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | <1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 运输 | Ambient temperature or ice pack. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
| 复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介绍
Interleukin-9 (IL-9) is a secreted Protein that belongs to the IL-7/ IL-9 family.Mature mouse IL-9 shares 57% and 74% amino acid sequence identity with human and rat IL-9, respectively. IL-9 supports IL-2 independent and IL-4 independent growth of helper T-cells. IL-9 stimulates cell proliferation and prevents apoptosis. It functions through the IL-9 Receptor (IL-9R), which activates different signal transducer and activator (STAT) Proteins and thus connects this Cytokine to various biological processes. IL-9 has been identified as a candidate gene for asthma. IL-9 is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
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