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人脉络膜血管内皮细胞
Human Choroidal Vascular Endothelial Cells
货号：CP-H092
规格：5×10⁵Cells/T25培养瓶
价格： ￥询价
培养基货号： CM-H092
产品概述
人脉络膜血管内皮细胞
Cat NO.: CP-H092
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产品名称：人脉络膜血管内皮细胞
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英文简称：CVECs
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组织来源：脉络膜组织
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产品规格：5×10⁵Cells/T25培养瓶
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细胞简介：
人脉络膜血管内皮细胞分离自眼球脉络膜组织；脉络膜在视网膜和巩膜之间，含有丰富血管和色素细胞，对外力冲击的耐受性较视网膜差，当眼球受到从前面来的外力的冲击作用通过玻璃体传到后极部时，坚硬的巩膜在其外面又有抵抗作用，使脉络膜在内外两种作用夹攻下而发生破裂和出血。脉络膜呈暗褐色，围绕视神经乳头部有照膜，为青绿色带金属光泽的三角形区。脉络膜是眼球中膜的后2/3处的薄膜，由纤维组织、小血管和毛细血管组成，软而薄，棕红色，在巩膜和视网膜之间，续连于睫状体后方。脉络膜的血循环营养视网膜外层，其含有的丰富色素起遮光暗房作用。主要功能是营养视网膜外层及玻璃体，并有遮光作用，使反射的物象清楚。同时对视觉系统起保护作用，对整个视觉神经有调节作用。续连于睫状体后方，含丰富的血管和色素细胞，有营养和遮光作用。
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方法简介：
普诺赛实验室分离的人脉络膜血管内皮细胞采用胶原酶-中性蛋白酶混合消化法并通过内皮细胞专用培养基培养筛选制备而来，细胞总量约为5×10⁵cells/瓶。
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质量检测：
普诺赛实验室分离的人脉络膜血管内皮细胞经CD31免疫荧光鉴定，纯度可达90%以上，且不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌等。
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培养信息：
包被条件 PLL（0.1mg/ml）或明胶（0.1%） 培养基 含FBS、生长添加剂、Penicillin、Streptomycin等 产品货号 CM-H092 换液频率 每2-3天换液一次 生长特性 贴壁 细胞形态 内皮细胞样 传代特性 可传2-3代 消化液 0.25%胰蛋白酶 人脉络膜血管内皮细胞体外培养周期有限；建议使用普诺赛配套的专用生长培养基及正确的操作方法来培养，以此保证该细胞的最佳培养状态。
参考文献
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Neutrophil extracellular traps boost laser-induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF-1α pathway (2023-08-08)
作者：Jia Zeng:1.Department of Pathogen Biology, Medical College, Nantong University, China. ; Ying Wang:1.Department of Ophthalmology, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, China. ; Manhui Zhu:1.Department of Pathology, Lixiang Eye Hospital of Soochow University, Suzhou, China. ; Min Wu:1.Department of Pathogen Biology, Medical College, Nantong University, China. ; Yamei Zhou:1.Department of Pathogen Biology, Medical College, Nantong University, China. ; Qiaoyun Wang:1.Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China. ; Yiqian Xu:1.Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China. ; Fei Lin:1.Medical College, Nantong University, China. ; Jiaqi Wang:1.Medical College, Nantong University, China. ; Yuxuan Li:1.Medical College, Nantong University, China. ; Shuang Liang:1.Medical College, Nantong University, China. ; Ziyu Wang:1.Medical Col
期刊：Neutrophil extracellular traps boost laser-induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF-1α pathway
影响因子 ：5.4
引用产品： 人脉络膜血管内皮细胞
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Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization (2023-04-17)
作者：Lele Li:1.Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China. ; Xin Cao:1.Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China. ; Lili Huang:1.Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China. ; Xiaobo Huang:1.Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China. ; Jiayi Gu:1.Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China. ; Xiaoli Yu:1.Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China. ; Yan Zhu:1.Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China. ; Yue Zhou:1.Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China. ; Yu Song:1.Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001,
期刊：Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization
影响因子 ：5.3
引用产品： 人脉络膜血管内皮细胞
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CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization (2003-01-20)
作者：Yamei Zhou:1.Department of Pathogen Biology, Medical College, Nantong University, Nantong, Jiangsu, China. ; Jia Zeng:1.Department of Pathogen Biology, Medical College, Nantong University, Nantong, Jiangsu, China. ; Yuanyuan Tu:1.Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou, Jiangsu, China. ; Lele Li:1.Department of Ophthalmology, the Second Affiliated Hospital of Nantong University, Nantong, Jiangsu, China. ; Shu Du:1.Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou, Jiangsu, China. ; Linling Zhu:1.Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou, Jiangsu, China. ; Xiaomin Cang:1.Department of Endocrinology, the Second Affiliated Hospital of Nantong University, Nantong, Jiangsu, China. ; Jiajie Lu:1.Medical College, Nantong University, Nantong, Jiangsu, China. ; Manhui Zhu:1.Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou, Jiangsu, China. ; Xiaojuan
期刊：CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization
影响因子 ：4.9
引用产品： 人脉络膜血管内皮细胞
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Geniposide alleviates choroidal neovascularization by downregulating HB-EGF release from RPE cells by downregulating the miR-145-5p/NF-κB axis (2005-01-20)
作者：Jiayi Gu:1.Department of Ophthalmology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China. ; Zhaoxian Qiu:1.Department of Ophthalmology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China. ; Lele Li:1.Department of Ophthalmology, Second Affiliated Hospital of Nantong University, Nantong, 226001, Jiangsu, China. ; Bai Qin:1.Department of Ophthalmology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China. ; Yamei Zhou:1.Department of Pathogen Biology, Medical College, Nantong University, Nantong, China. ; Yu Liu:1.Department of Ophthalmology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China. ; Xiaojuan Liu:1.Department of Pathogen Biology, Medical College, Nantong University, Nantong, China. Electronic address: lxj@ntu.edu.cn. ; Manhui Zhu:1.Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou, Jiangsu, China. Electronic address: zhumanhuieye@126.com. ; Aimin Sang:1.Department of Ophthalm
期刊：Geniposide alleviates choroidal neovascularization by downregulating HB-EGF release from RPE cells by downregulating the miR-145-5p/NF-κB axis
DOI：10.1016/j.exer.2021.108624
影响因子 ：3.4
引用产品： 人脉络膜血管内皮细胞
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MLN4924 inhibits hedgehog signaling pathway and activates autophagy to alleviate mouse laser-induced choroidal neovascularization lesion (2009-00-20)
作者：Laiqing Xie:1.Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. ; Xiaoyan Ji:1.Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. ; Yuanyuan Tu:1.Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou, Jiangsu, China. ; Kun Wang:1.Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou, Jiangsu, China. ; Linling Zhu:1.Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou, Jiangsu, China. ; Xinwei Zeng:1.Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. ; Xue Wang:1.Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. ; Ji Zhang:1.Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. Electronic address: jizhang0068@sina.com. ; Manhui
期刊：MLN4924 inhibits hedgehog signaling pathway and activates autophagy to alleviate mouse laser-induced choroidal neovascularization lesion
DOI：10.1016/j.biopha.2020.110654
影响因子 ：7.5
引用产品： 人脉络膜血管内皮细胞
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Antagonistic effects of exogenous Slit2 on VEGF‑induced choroidal endothelial cell migration and tube formation (2004-09-20)
作者：Yanling Tang:1.Department of Ophthalmology, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, P.R. China. ; Xiyuan Zhou:1.Department of Ophthalmology, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, P.R. China. ;
期刊：Antagonistic effects of exogenous Slit2 on VEGF‑induced choroidal endothelial cell migration and tube formation
影响因子 ：2.7
引用产品： 人脉络膜血管内皮细胞
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