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产品概述
产品信息
| 别名 | BCGF, BCDF, B-cell Stimulating Factor (BSF-1) |
| 物种 | Mouse |
| 表达宿主 | E.coli |
| 序列信息 | MHIHGCDKNHLREIIGILNEVTGEGTPCTEMDVPNVLTATKNTTESELVCRASKVLRIFYLKHGKTPCLKKNSSVLMELQRLFRAFRCLDSSISCTMNESKSTSLKDFLESLKSIMQMDYS with polyhistidine tag at the C-terminus. |
| 检索号 | P07750.1 |
| 分子量 | 14.5 kDa |
| 表观分子量 | 14 kDa |
| 标签 | His-tag at the C-terminus |
| 生物活性 | Measure by its ability to induce HT-2 cells proliferation.The ED50 for this effect is <1 ng/mL.The specific activity of recombinant mouse IL-4 is approximately >1 x 10^6 IU/mg. |
产品特性
| 纯度 | >98% as determined by SDS-PAGE. Ni-NTA chromatography |
| 内毒素 | <0.1 EU per 1 μg of the protein by the LAL method. |
| 保存 | Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution, store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1% BSA,10%FBS,5%HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months. |
| 运输 | Ambient temperature or ice pack. |
| 制剂 | The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. |
| 复融 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL.Do Not Vortex! Vigorous shaking may impair the biological activity of the protein. |
背景介绍
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4 in a positive feedback loop. The cell that initially produces IL-4, thus inducing Th2 differentiation, has not been identified, but recent studies suggest that basophils may be the effector cell. It is closely related and has functions similar to Interleukin 13.
参考文献
文献列表
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Dual-Enzyme-Instructed Peptide Self-Assembly to Boost Immunogenic Cell Death by Coordinating Intracellular Calcium Overload and Chemotherapy (2025-01-04)
期刊：ACS Nano
影响因子 ：15.8
引用产品： GM-CSF/CSF2/MGI-I/MGI-IGM, Mouse, Recombinant , IL-4/BSF-1, Mouse, Recombinant
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