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兔骨髓间充质干细胞
Rabbit Bone Marrow Mesenchymal Stem Cells
货号：CP-Rb007
规格：5×10⁵Cells/T25培养瓶
价格： ￥4380
培养基货号： CM-Rb007
产品概述
兔骨髓间充质干细胞
Cat NO.: CP-Rb007
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产品名称：兔骨髓间充质干细胞
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英文简称：BMSCs,MSCs
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组织来源：骨髓
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产品规格：5×10⁵Cells/T25培养瓶
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细胞简介：
兔骨髓间充质干细胞(BMSC)分离自骨髓；骨髓是机体的造血组织，位于身体的许多骨骼内。成年动物的骨髓分两种：红骨髓和黄骨髓。红骨髓能制造红细胞、血小板和各种白细胞。血小板有止血作用，白细胞能杀灭与抑制各种病原体，包括细菌、病毒等；某些淋巴细胞能制造抗体。因此，骨髓不但是造血器官，它还是重要的免疫器官。骨髓是存在于长骨(如肱骨、股骨)的骨髓腔和扁平骨(如髂骨)的稀松骨质间的网眼中，是一种海绵状的组织，能产生血细胞的骨髓略呈红色，称为红骨髓。出生时，红骨髓充满全身骨髓腔，随着年龄增大，脂肪细胞增多，相当部分红骨髓被黄骨髓取代，最后几乎只有扁平骨骨髓腔中有红骨髓。骨髓基质系统内存在的骨髓间充质干细胞是一种除造血干细胞以外的、具有高度自我更新能力和多向分化潜能的干细胞，可以向骨、软骨、肌组织、皮肤、脂肪、神经等多种组织分化，因此可以作为组织工程中的种子细胞。在骨髓中，BMSC占骨髓有核细胞总数的0.001%-0.1%，含量极低。骨髓间充质干细胞的体外培养条件要求较高，在培养过程中，受贴壁时间、种植密度、血清含量、培养温度和培养基pH值等条件的影响。
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方法简介：
普诺赛实验室分离的兔骨髓间充质干细胞采用冲洗骨髓、密度梯度离心、差速贴壁法结合培养基筛选制备而来，细胞总量约为5×10⁵cells/瓶。
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质量检测：
普诺赛实验室分离的兔骨髓间充质干细胞经CD90免疫荧光鉴定，纯度可达90%以上，且不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌等。
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培养信息：
包被条件 培养基 含FBS、生长添加剂、Penicillin、Streptomycin等 产品货号 CM-Rb007 换液频率 每2-3天换液一次 生长特性 贴壁 细胞形态 成纤维细胞样 传代特性 可传5代左右；3代以内状态最佳 消化液 0.25%胰蛋白酶 兔骨髓间充质干细胞体外培养周期有限；建议使用普诺赛配套的专用生长培养基及正确的操作方法来培养，以此保证该细胞的最佳培养状态。
参考文献
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3D-printed near-infrared-light-responsive on-demand drug-delivery scaffold for bone regeneration (2024-02-22)
作者：Dong Qinyuan:1.National Center for Stomatology, National Clinical Research Center for Oral Disease, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, NHC Key Laboratory of Digital Stomatology, Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, China. ; Wan Zhuqing:1.National Center for Stomatology, National Clinical Research Center for Oral Disease, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, NHC Key Laboratory of Digital Stomatology, Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, China. ; Li Qing:1.National Center for Stomatology, National Clinical Research Center for Oral Disease, National Engineering Research Center of Oral Biomate
期刊：3D-printed near-infrared-light-responsive on-demand drug-delivery scaffold for bone regeneration
DOI：10.1016/j.bioadv.2024.213804
影响因子 ：0.0
引用产品： 兔骨髓间充质干细胞
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A lubricant and adhesive hydrogel cross-linked from hyaluronic acid and chitosan for articular cartilage regeneration (2023-06-07)
作者：Haofeng Qiu:1.School of Materials Science and Engineering, Nanjing University of Science & Technology, Nanjing 210094, PR China; Cixi Institute of Biomedical Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315300, PR China. ; Junjie Deng:1.Cixi Institute of Biomedical Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315300, PR China; Cixi Biomedical Research Institute, Wenzhou Medical University, Zhejiang 325035, PR China. ; Rufang Wei:1.Cixi Institute of Biomedical Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315300, PR China; Cixi Biomedical Research Institute, Wenzhou Medical University, Zhejiang 325035, PR China. ; Xiang Wu:1.Cixi Institute of Biomedical Engineering, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315300, PR China; School of Medicine, Ningbo
期刊：A lubricant and adhesive hydrogel cross-linked from hyaluronic acid and chitosan for articular cartilage regeneration
DOI：10.1016/j.ijbiomac.2023.125249
影响因子 ：8.2
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Microporous Implants Modified by Bifunctional Hydrogel with Antibacterial and Osteogenic Properties Promote Bone Integration in Infected Bone Defects (2023-04-16)
作者：Yiping Pu:1.Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China. ; 2.National Clinical Research Center for Oral Diseases, Shanghai 200011, China. ; 3.Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai 200001, China. ; 4.Research Unit of Oral and Maxillofacial Regenerative Medicine, Chinese Academy of Medical Sciences, Shanghai 200001, China. ; Xuecai Lin:1.Hongqiao Community Health Service Center, Minhang District, Shanghai 201103, China. ; Qiang Zhi:1.National Clinical Research Center for Oral Diseases, Shanghai 200011, China. ; 2.Department of Implant Dentistry, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China. ; 3.Shanghai Key Laboratory of Stomatology, National Center for Stomatology, Shanghai 200011, China. ; Shichong Q
期刊：Microporous Implants Modified by Bifunctional Hydrogel with Antibacterial and Osteogenic Properties Promote Bone Integration in Infected Bone Defects
影响因子 ：4.8
引用产品： 兔骨髓间充质干细胞 , 兔骨髓间充质干细胞成骨诱导分化培养基
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Reactive Oxygen Species Scavenging Hydrogel Regulates Stem Cell Behavior and Promotes Bone Healing in Osteoporosis (2023-09-12)
作者：Yuanjian Ye:1.Department of Orthopaedic, Huizhou First Hospital, Guangdong Medical University, Huizhou, 516003, Guangdong, China. ; Haobo Zhong:1.Department of Orthopaedic, Huizhou First Hospital, Guangdong Medical University, Huizhou, 516003, Guangdong, China. ; Shoubin Huang:1.Department of Orthopaedic, Huizhou First Hospital, Guangdong Medical University, Huizhou, 516003, Guangdong, China. ; Weiqiang Lai:1.Department of Orthopaedic, Huizhou First Hospital, Guangdong Medical University, Huizhou, 516003, Guangdong, China. ; Yizhi Huang:1.Guangdong Medical University, DongGuan, 523000, Guangdong, China. ; Chunhan Sun:1.Department of Orthopaedic, Huizhou First Hospital, Guangdong Medical University, Huizhou, 516003, Guangdong, China. ; Yanling Zhang:1.Department of Emergency Medicine, Huizhou First Hospital, Guangdong Medical University, Huizhou, 516003, Guangdong, China. 13414688677@163.com. ; Shaowei Zheng:1.Department of Orthopaedic, Huizhou First Hospital, Guangdong Medical U
期刊：Reactive Oxygen Species Scavenging Hydrogel Regulates Stem Cell Behavior and Promotes Bone Healing in Osteoporosis
DOI：10.1007/s13770-023-00561-w
影响因子 ：3.6
引用产品： 兔骨髓间充质干细胞 , 兔骨髓间充质干细胞成骨诱导分化培养基
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Effect of bone marrow mesenchymal stem cell transplantation combined with lugua polypeptide injection on osteoarthritis in rabbit knee joint (2008-01-20)
作者：Huajun Huang:1.Department of Trauma and Joint Surgery, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Shunde, China. ; 2.Department of Foot and Ankle Surgery, Center for Orthopaedic Surgery, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China. ; Ping Zhang:1.Devision of Orthopaedics and Traumatology, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China. ; Chunling Xiang:1.Devision of Orthopaedics and Traumatology, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China. ; Canjun Zeng:1.Department of Foot and Ankle Surgery, Center for Orthopaedic Surgery, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China. ; Qingjun Du:1.Department of Trauma and Joint Surgery, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Shunde, China. ; Wenhua Huang:1.Department of Foot and Ankle Surgery, Ce
期刊：Effect of bone marrow mesenchymal stem cell transplantation combined with lugua polypeptide injection on osteoarthritis in rabbit knee joint
DOI：10.1080/03008207.2021.1962314
影响因子 ：2.9
引用产品： 兔骨髓间充质干细胞
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