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产品概述
名称 | COV434 (人卵巢颗粒肿瘤细胞) (STR鉴定正确) |
别称 | COV-434; COV 434 |
种属 | 人 |
生长特性 | 贴壁(有聚团) |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
年龄(性别) | 女性;26岁 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 卵巢癌细胞 |
保藏机构 | ECACC; 07071909 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 10,11 D2S1338 25 D3S1358 15,19 D5S818 10,11 D7S820 8 D8S1179 13,14 D13S317 8,12 D16S539 9,12 D18S51 10,15 D19S433 14,15 D21S11 28 FGA 24,25 PentaD 10,12 PentaE 12 TH01 9.3 TPOX 9,11 vWA 16,18 D6S1043 11 D12S391 22,23 D2S441 10,14 -
STR鉴定图
参考文献
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Advanced oxidation protein products attenuate the autophagy-lysosome pathway in ovarian granulosa cells by modulating the ROS-dependent mTOR-TFEB pathway (2024-02-21)
作者:Xing-Yu Zhou:1.Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, PR China. ; Yun-Hui Lai:1.Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, PR China. ; Jun Zhang:1.Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, PR China. ; Ying Li:1.Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, PR China. ; Xiao-Min Wu:1.Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, PR China. ; Yi-Zhen Yang:1.Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, PR China. ; Xiao-Fei Zhang:1.Center for Reproductive Med
期刊:Advanced oxidation protein products attenuate the autophagy-lysosome pathway in ovarian granulosa cells by modulating the ROS-dependent mTOR-TFEB pathway
DOI:10.1038/s41419-024-06540-w
影响因子 :9.0
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Resveratrol-βcd inhibited premature ovarian insufficiency progression by regulating granulosa cell autophagy (2024-01-15)
作者:Bingbing Hu:1.The Reproductive Medicine Center, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China. hbbanzi@163.com. ; Xiushuang Zheng:1.Department of Reproductive Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, China. ; Wei Zhang:1.Emergency and Disaster Medical Center, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China. ;
期刊:Resveratrol-βcd inhibited premature ovarian insufficiency progression by regulating granulosa cell autophagy
DOI:10.1186/s13048-024-01344-0
影响因子 :4.0
引用产品: COV434 细胞 , RAW 264.7 细胞
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Celastrol induces premature ovarian insufficiency by inducing apoptosis in granulosa cells (2023-11-11)
作者:Fan Wen:1.Department of Rehabilitation Medicine, Shunde Hospital of Southern Medical University, Foshan 528000, China; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. ; Dandan Liu:1.State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. ; Mingming Wang:1.Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China. ; Shujie Zhang:1.State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. ; Wenhua Kuang:1.Stat
期刊:Celastrol induces premature ovarian insufficiency by inducing apoptosis in granulosa cells
DOI:10.1016/j.biopha.2023.115815
影响因子 :7.5
引用产品: COV434 细胞
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Pterostilbene ameliorates oxidative damage and ferroptosis in human ovarian granulosa cells by regulating the Nrf2/HO-1 pathway (2023-03-09)
作者:Xin Chen:1.Reproductive Medical Center, Renmin Hospital of Wuhan University and Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development, Wuhan, Hubei, China. ; Qian Lin Song:1.Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China. ; Ze Hong Li:1.Reproductive Medical Center, Renmin Hospital of Wuhan University and Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development, Wuhan, Hubei, China. ; Rui Ji:1.Reproductive Medical Center, Renmin Hospital of Wuhan University and Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development, Wuhan, Hubei, China. ; Jia Yu Wang:1.Reproductive Medical Center, Renmin Hospital of Wuhan University and Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development, Wuhan, Hubei, China. ; Ming Liang Cao:1.Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan, China.
期刊:Pterostilbene ameliorates oxidative damage and ferroptosis in human ovarian granulosa cells by regulating the Nrf2/HO-1 pathway
影响因子 :3.9
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Follicular fluid derived exosomal miR-4449 regulates cell proliferation and oxidative stress by targeting KEAP1 in human granulosa cell lines KGN and COV434 (2023-07-29)
作者:Min Wang:1.Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. ; Yixuan Sun:1.Department of Gynecology and Obstetrics, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China. ; Dong Yuan:1.Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. ; Song Yue:1.Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. ; Zhu Yang:1.Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. Electronic address: yangzhu@hospital.cqmu.edu.cn. ;
期刊:Follicular fluid derived exosomal miR-4449 regulates cell proliferation and oxidative stress by targeting KEAP1 in human granulosa cell lines KGN and COV434
DOI:10.1016/j.yexcr.2023.113735
影响因子 :3.7
引用产品: KGN 细胞 , COV434 细胞 , 293T [HEK-293T] 细胞
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Toxicity of polystyrene nanoparticles for mouse ovary and cultured human granulosa cells (2022-12-09)
作者:Jin Huang:1.Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, People's Republic of China. ; Liping Zou:1.Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, People's Republic of China. ; Meng Bao:1.Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, People's Republic of China. ; Qiwen Feng:1.Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, People's Republic of China. ; Wei Xia:1.Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, People's Republic of China. Electronic address: tjxiawei@hust.edu.cn. ; Changhong Zhu:1.Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Techn
期刊:Toxicity of polystyrene nanoparticles for mouse ovary and cultured human granulosa cells
DOI:10.1016/j.ecoenv.2022.114371
影响因子 :7.1
引用产品: COV434 细胞
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Maternal exposure to PM2.5 decreases ovarian reserve in neonatal offspring mice through activating PI3K/AKT/FoxO3a pathway and ROS-dependent NF-κB pathway (2022-10-13)
作者:Yingying Chen:1.Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Yueyue Xi:1.Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Milu Li:1.Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Yaling Wu:1.Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Wei Yan:1.Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Laboratory of Environment and Health, College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China. ; Jun Dai:1.Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical Coll
期刊:Maternal exposure to PM2.5 decreases ovarian reserve in neonatal offspring mice through activating PI3K/AKT/FoxO3a pathway and ROS-dependent NF-κB pathway
影响因子 :4.6
引用产品: COV434 细胞
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CircRNA circ_0043533 facilitates cell growth in polycystic ovary syndrome by targeting miR-1179 (2003-02-20)
作者:Ai-Xue Chen:1.Department of Gynecology, Changxing People's Hospital of Chongming District, Shanghai, China. ; Rui-Ying Jin:1.Department of Gynecology, Jiaojiang Maternal and Child Health Hospital, Taizhou City, Zhejiang, China. ; Wei-Mei Zhou:1.Department of Ultrasound, Jiaojiang Maternal and Child Health Hospital, Taizhou City, Zhejiang, China. ; Yong-Ju Ye:1.Department of Gynaecology, Lishui Hospital of Traditional Chinese Medicine, Lishui, Zhejiang, China. ; Jia-Li Lu:1.Department of Gynecology, Huzhou Maternity & Child Health Care Hospital, Huzhou, Zhejiang, China. ; Yue-Fang Ren:1.Department of Gynecology, Huzhou Maternity & Child Health Care Hospital, Huzhou, Zhejiang, China. ; Fei-Lan Xuan:1.Department of Gynecology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. Electronic address: xuanfile@163.com. ;
期刊:CircRNA circ_0043533 facilitates cell growth in polycystic ovary syndrome by targeting miR-1179
DOI:10.1016/j.repbio.2022.100637
影响因子 :2.1
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MiRNA-99a can regulate proliferation and apoptosis of human granulosa cells via targeting IGF-1R in polycystic ovary syndrome (2010-08-20)
作者:Yudi Geng:1.Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. ; Cong Sui:1.Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. ; Yang Xun:1.Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. ; Qiaohong Lai:1.Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. lqh74@126.com. ; Lei Jin:1.Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. leijintj@163.com. ;
期刊:MiRNA-99a can regulate proliferation and apoptosis of human granulosa cells via targeting IGF-1R in polycystic ovary syndrome
影响因子 :3.1
引用产品: COV434 细胞
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