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产品概述
| 名称 | CAL-62 (人甲状腺癌细胞(未分化)) (STR鉴定正确) |
| 别称 | Cal-62; CAL 62; Cal 62; CAL62; Centre Antoine Lacassagne-62 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | Established from the thyroid gland (right lobe) of a 70-year-old woman with thyroid anaplastic carcinoma in 1988; described as being tumorigenic in heterotransplanted nude mice |
| 年龄（性别） | 女性；70岁 |
| 组织来源 | 甲状腺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 甲状腺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~24 hours (DSMZ) |
| 保藏机构 | DSMZ; ACC-448 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 9,12 D2S1338 19,23 D3S1358 16 D5S818 9,12 D7S820 10 D8S1179 13 D13S317 12 D16S539 12,13 D18S51 16 D19S433 14 D21S11 32.2 FGA 19 PentaD 13 PentaE 5,10 TH01 7,9 TPOX 8,9 vWA 16 D6S1043 12 D12S391 22 D2S441 11 -
STR鉴定图
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参考文献
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RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex(2023/02/21)
作者：Xu Debin, Yu Jichun, Yang Yuting, Du Yunyan, Lu Hongcheng, Zhang Shouhua, Feng Qian, Yu Yi, Hao Liang, Shao Jun, Chen Leifeng
期刊：Cell and Bioscience
DOI：10.1186/s13578-023-00987-8
影响因子 ：7.500
引用产品：CL-0575 CL-0617 CL-0618 CL-0624 CL-0643 CL-0648 CL-0649
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Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D(2024/01/10)
作者：Chuan Zhou, Zisheng Fan, Yuejiao Gu
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c01622
影响因子 ：7.300
引用产品：CL-0618
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Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers(2023/03/10)
作者：Zehui Zhou, Guizhen Zhou, Chuan Zhou
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c00075
影响因子 ：7.300
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Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer(2023/06/19)
作者：Qingling Yuan, Yuxia Fan, Zheng Liu
期刊：APOPTOSIS
DOI：10.1007/s10495-023-01861-1
影响因子 ：7.200
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Cytotoxic and Antibacterial Meroterpenoids Isolated from the Marine-Derived Fungus Talaromyces sp. M27416(2024/04/20)
作者：Lingzhi Tang, Jinmei Xia, Zhongwei Chen
期刊：Marine Drugs
影响因子 ：5.400
引用产品：CL-0618
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Anti-Anaplastic Thyroid Cancer (ATC) Effects and Mechanisms of PLX3397 (Pexidartinib), a Multi-Targeted Tyrosine Kinase Inhibitor (TKI)(2022/12/28)
作者：Jingtao Luo, Yun Wang, Lingkun Zhao
期刊：Cancers
影响因子 ：5.200
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Immunological characteristics of immunogenic cell death genes and malignant progression driving roles of TLR4 in anaplastic thyroid carcinoma(2023/11/21)
作者：Tong Xu, Chaozhuang Zhu, Feifeng Song
期刊：BMC CANCER
DOI：10.1186/s12885-023-11647-y
影响因子 ：3.800
引用产品：CL-0618
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Identification and Validation of Novel Genes in Anaplastic Thyroid Carcinoma via Bioinformatics Analysis(2023/01/30)
作者：Shengnan Wang, Jing Wu, Congcong Guo
期刊：Cancer Management and Research
影响因子 ：3.300
引用产品：CL-0618
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DNMT1/DNMT3a-mediated promoter hypermethylation and transcription activation of ICAM5 augments thyroid carcinoma progression(2024/01/17)
作者：Zanbin Li, Yong Ying, Xiangtai Zeng
期刊：FUNCTIONAL & INTEGRATIVE GENOMICS
DOI：10.1007/s10142-024-01293-3
影响因子 ：2.900
引用产品：CL-0618
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