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产品概述
名称 | OCI-Ly3 (人弥漫大 B 细胞淋巴瘤细胞) (STR鉴定正确) |
别称 | OCI-LY3; OCI-ly3; OCI-LY-3; Oci-Ly-3; OCI-Ly 3; OCILY-3; OCI-Ly03; OCI Ly3; OCILY3; Ly3; LY3 |
种属 | 人 |
生长特性 | 悬浮细胞 |
细胞形态 | 圆形细胞,聚团生长 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
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推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3天/次 |
背景描述 | established in 1983 from the bone marrow sample of a 52-year-old man with B-cell non-Hodgkin lymphoma (B-NHL, diffuse large B-cell lymphoma, DLBCL, stage 4B) at relapse; cells were described in the literature to be EBV-negative and lacking a classical t(8;14) translocation. Exome and RNA sequence data are available (see Ref 18187 and Exome sequence and RNA-Seq) |
年龄(性别) | 男性;52岁 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 淋巴瘤细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~24 hours (DSMZ) |
保藏机构 | DSMZ; ACC-761 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,12 D2S1338 24 D3S1358 14 D5S818 12 D7S820 11,12 D8S1179 13 D13S317 11 D16S539 11,12 D18S51 17 D19S433 13,15 D21S11 28 FGA 21,23 PentaD 9,10 PentaE 7,11 TH01 7,9.3 TPOX 8,12 vWA 17 D6S1043 14 D12S391 18,18.3 D2S441 11 -
STR鉴定图
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参考文献
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Diffuse large B-cell lymphoma cell-derived exosomal NSUN2 stabilizes PDL1 to promote tumor immune escape and M2 macrophage polarization in a YBX1-dependent manner (2025-01-24)
期刊:ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影响因子 :3.8
引用产品: THP-1 细胞 , OCI-LY-10 细胞 , OCI-Ly3 细胞 , U-2932 细胞
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Inhibition of CDGSH iron?sulfur domain 2 exhibits tumor-suppressing effects on diffuse large B-cell lymphoma (DLBCL) by inducing ferroptosis through the regulation of the NRF2/SLC7A11/GPX4 pathway (2024-11-08)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2024.117148
影响因子 :3.3
引用产品: OCI-Ly3 细胞 , SU-DHL-4 细胞 , HMy2.CIR 细胞 , WSU-DLCL2 细胞 , U-2932 细胞
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