产品中心Cell Resources
联系我们CONTACT US
- 400-999-210024小时服务热线
产品概述
名称 | SU-DHL-4 (人B淋巴瘤细胞) (STR鉴定正确) |
别称 | SUDHL4; Sudhl4; SUDHL-4; Sudhl-4; SuDHL 4; SUD-4; SUD4; SU4; Stanford University-Diffuse Histiocytic Lymphoma-4; DHL-4; DHL4 |
种属 | 人类 |
生长特性 | 悬浮细胞 |
细胞形态 | 淋巴母细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 5×10^5-1×10^6cells/mL |
推荐换液频率 | 2-3次/周 |
注意事项 | 该细胞为悬浮细胞,请注意离心收集细胞悬液;请勿直接倒掉细胞培养液。 |
背景描述 | Established from the peritoneal effusion of a 38-year-old man with B-NHL (diffuse large cell, cleaved cell type; originally described as "diffuse histiocytic lymphoma") in 1975; cell line carries EZH2 Y641S mutation; assigned to GCB-like lymphoma subtype (germinal center B-cell). Exome and RNA sequence data are available (see Ref 18187 and Exome sequence and RNA-Seq) |
年龄(性别) | 男性;38岁 |
组织来源 | 腹腔积液 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 淋巴瘤细胞 |
倍增时间 | ~40 hours |
基因表达情况 | IgG+; Kappa+; IgM-; IgA-; IgD-; Lambda-; This cell line has relatively high expression levels of Bax; Bak; AIF; high caspase-9 activity. |
保藏机构 | ATCC; CRL-2957 DSMZ; ACC-495 |
STR鉴定
-
STR位点信息
Amelogenin X,Y CSF1PO 12 D2S1338 17,19 D3S1358 15,16 D5S818 11,12 D7S820 8,11 D8S1179 13 D13S317 12 D16S539 11,13 D18S51 14,16 D19S433 14,15.2 D21S11 29,31 FGA 19,21 PentaD 9,14 PentaE 7,12 TH01 6,9.3 TPOX 9,11 vWA 18,19 D6S1043 11 D12S391 18,20 D2S441 11,14 -
STR鉴定图
参考文献
-
Anti-CD79b/CD3 bispecific antibody combined with CAR19-T cells for B-cell lymphoma treatment(2023/09/14)
作者:Weiwei Zheng, Hang Zhou, Ping Li
期刊:CANCER IMMUNOLOGY IMMUNOTHERAPY
DOI:10.1007/s00262-023-03526-z
影响因子 :5.800
-
Chidamide and orelabrutinib synergistically induce cell cycle arrest and apoptosis in diffuse large B-cell lymphoma by regulating the PI3K/AKT/mTOR pathway(2024/02/21)
作者:Chunyan Wu, Shilv Chen, Zhimin Wu
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-024-05615-7
影响因子 :3.600
引用产品:CL-0692
FAQs
Q:{{item.question}}
A:
产品资料
识别码示意图