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TGF-β1, Human, Recombinant
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货号：PCK091

价格：¥11803480628014680

规格：

10µg

10µg
50µg
100µg
500µg

数量： - +

说明书

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产品概述

产品信息

别名	Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB
物种	Human
表达宿主	CHO Stable Cells
序列信息	Ala279-Ser390
检索号	P01137
分子量	12.8 kDa
表观分子量	13 kDa
生物活性	Measured by its ability to inhibit the IL-4-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is 4-40 pg/ml.

产品特性

纯度	>95% as determined by reducing SDS-PAGE.
内毒素	<1.0 EU per µg as determined by LAL test.
保存	Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输	Ambient temperature or ice pack.
制剂	Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mMNacl, pH2.5.
复融	Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

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FAQs

Q：收到细胞因子产品用什么溶剂复融？

A：1、细胞因子产品大部分为冻干形式发货，少部分液体形式发货； 2、液体形式因子产品不需要复溶，具体浓度详见产品标签，按照实验需要用含载体蛋白(如0.1% BSA，10%FBS，5%HSA 或 5% 海藻糖)的溶液进一步稀释后分装冷冻保存即可； 3、冻干粉状态的因子产品需指定溶剂复溶，请参考产品说明书【复融】方法，按照要求使用对应溶剂溶解，部分需要无菌水以外的特殊溶剂溶解的产品则随货会赠送相应的复融试剂；冻干粉溶解后如您需要进一步稀释分装，需使用含载体蛋白(如0.1% BSA，10%FBS，5%HSA 或 5% 海藻糖)的溶液进一步稀释后分装冷冻保存。