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产品概述
名称 | BHT101 (人甲状腺癌细胞(未分化)) (STR鉴定正确) |
别称 | BHT-101 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:6 |
推荐换液频率 | 2-3次/周 |
背景描述 | Established from the lymph node metastasis of a 63-year-old woman with anaplastic papillary thyroid carinoma; cells were described in the literature to not produce hormones, but to be partly positive for thyroglobulin- and thyroxine (T4) |
年龄(性别) | 女性;63岁 |
组织来源 | 甲状腺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 甲状腺癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | 24 hours (PubMed=8099464); ~2-3 days (DSMZ) |
保藏机构 | DSMZ; ACC-279 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12,13 D2S1338 20,23 D3S1358 16,17 D5S818 10,11 D7S820 10,11 D8S1179 13,15 D13S317 12 D16S539 9,11 D18S51 12,15 D19S433 13,14,15 D21S11 29,32.2 FGA 18,24 PentaD 9 PentaE 10,17 TH01 9,9.3 TPOX 8 vWA 19 D6S1043 12,14 D12S391 17,22 D2S441 10,11.3 -
STR鉴定图
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参考文献
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The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy (2024-04-28)
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2024.155670
影响因子 :7.9
引用产品: DMEM高糖 培养基 , MEM(含NEAA) 培养基 , OCUT-2C 细胞 , 8305C 细胞 , RPMI-1640 培养基 , BHT101 细胞 , C643 细胞
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YTHDF2 promotes anaplastic thyroid cancer progression by activating the DDIT4/AKT/mTOR signaling pathway (2024-11-26)
期刊:Biology Direct
DOI:10.1186/s13062-024-00566-y
影响因子 :5.7
引用产品: KHM-5M 细胞 , 特级胎牛血清 , KMH-2 细胞 , BHT101 细胞 , FTC-133 细胞
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DNMT1/DNMT3a-mediated promoter hypermethylation and transcription activation of ICAM5 augments thyroid carcinoma progression (2024-01-17)
期刊:FUNCTIONAL & INTEGRATIVE GENOMICS
DOI:10.1007/s10142-024-01293-3
影响因子 :2.9
引用产品: B-CPAP [BC-PAP; BCPAP] 细胞 , 8305C 细胞 , BHT101 细胞 , CAL-62 细胞
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RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex (2023-02-21)
期刊:Cell and Bioscience
DOI:10.1186/s13578-023-00987-8
影响因子 :7.5
引用产品: TPC-1 细胞 , B-CPAP [BC-PAP; BCPAP] 细胞 , KTC-1 细胞 , C643 细胞 , CAL-62 细胞 , 8305C 细胞 , KMH-2 细胞 , KHM-5M 细胞 , BHT101 细胞
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Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) Plays an Oncogenic Role in Thyroid Carcinoma by Activating the AKT and ERK1/2 Signaling Pathway (2023-07-01)
期刊:CURRENT CANCER DRUG TARGETS
DOI:10.2174/1568009623666230118111745
影响因子 :3.0
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FOXA2 suppresses PKM2 transcription and affects the Wnt/β-catenin activity to block aerobic glycolysis in thyroid carcinoma (2023-03-22)
期刊:CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
影响因子 :2.9
引用产品: B-CPAP [BC-PAP; BCPAP] 细胞 , BHT101 细胞 , 293T [HEK-293T] 细胞
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Anti-Anaplastic Thyroid Cancer (ATC) Effects and Mechanisms of PLX3397 (Pexidartinib), a Multi-Targeted Tyrosine Kinase Inhibitor (TKI) (2022-12-28)
期刊:Cancers
影响因子 :6.6
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Tripartite motif containing 63, regulated by E26 transformation specific variant 4, facilitates the thyroid carcinoma progression and the AKT, p38, and ERK signaling pathways (2022-04-04)
期刊:MOLECULAR AND CELLULAR ENDOCRINOLOGY
影响因子 :4.1
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