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产品概述
| 名称 | 8305C (人甲状腺癌细胞(未分化)) (STR鉴定正确) |
| 别称 | 8305c; 8305-C; 8305C_1 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:5 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | Established from the primary tumor of a 67-year-old woman with primary thyroid carcinoma (undifferentiated carcinoma, composed of spindle, polygonal and giant cells) |
| 年龄（性别） | 女性；67岁 |
| 组织来源 | 甲状腺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 甲状腺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~54 hours (DSMZ); 43 hours (ECACC); ~43 hours (ICLC) |
| 保藏机构 | DSMZ; ACC-133 ECACC; 94090183 JCRB; JCRB0824 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 9,12 D2S1338 17,25 D3S1358 15 D5S818 10,13 D7S820 8,10 D8S1179 11,14 D13S317 9 D16S539 10,11 D18S51 13,24 D19S433 14 D21S11 30,32.2 FGA 21,22 PentaD 10 PentaE 15,17 TH01 6,7 TPOX 8 vWA 14,16 D6S1043 13 D12S391 19,25 D2S441 11,12 -
STR鉴定图
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参考文献
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DNMT1/DNMT3a-mediated promoter hypermethylation and transcription activation of ICAM5 augments thyroid carcinoma progression (2024-01-17)
作者：Zanbin Li:1.Department of Thyroid and Hernia Surgery, First Affiliated Hospital of Gannan Medical College, No. 128, Jinling West Road, Ganzhou, 341000, Jiangxi, People's Republic of China. ; Yong Ying:1.Department of Thyroid and Hernia Surgery, First Affiliated Hospital of Gannan Medical College, No. 128, Jinling West Road, Ganzhou, 341000, Jiangxi, People's Republic of China. ; Xiangtai Zeng:1.Department of Thyroid and Hernia Surgery, First Affiliated Hospital of Gannan Medical College, No. 128, Jinling West Road, Ganzhou, 341000, Jiangxi, People's Republic of China. ; Jiafeng Liu:1.Department of Thyroid and Hernia Surgery, First Affiliated Hospital of Gannan Medical College, No. 128, Jinling West Road, Ganzhou, 341000, Jiangxi, People's Republic of China. ; Yang Xie:1.Department of Thyroid and Hernia Surgery, First Affiliated Hospital of Gannan Medical College, No. 128, Jinling West Road, Ganzhou, 341000, Jiangxi, People's Republic of China. ; Zefu Deng:1.Department of Thyroid a
期刊：DNMT1/DNMT3a-mediated promoter hypermethylation and transcription activation of ICAM5 augments thyroid carcinoma progression
DOI：10.1007/s10142-024-01293-3
影响因子 ：2.9
引用产品： B-CPAP [BC-PAP; BCPAP] 细胞 , 8305C 细胞 , BHT101 细胞 , CAL-62 细胞
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RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex (2023-02-21)
作者：Debin Xu:1.Department of Thyroid Surgery, Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330008, China. ; Jichun Yu:1.Department of Thyroid Surgery, Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330008, China. ; Yuting Yang:1.Department of Intensive Care Unit, First Affiliated Hospital of Nanchang University, No. 17, Yongwai Main Street, Nanchang, 330006, China. ; Yunyan Du:1.School of Pharmacy, Nanchang University, No. 471, Bayi Road, Nanchang, 330006, China. ; Hongcheng Lu:1.Department of General Surgery, Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330008, China. ; Shouhua Zhang:1.Department of General Surgery, Affiliated Children's Hospital of Nanchang University, No. 122, Yangming Road, Nanchang, 330006, China. ; Qian Feng:1.Department of General Surgery, Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330008, China. ; Yi Yu:1.Department of Urolo
期刊：RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex
DOI：10.1186/s13578-023-00987-8
影响因子 ：7.5
引用产品： TPC-1 细胞 , B-CPAP [BC-PAP; BCPAP] 细胞 , KTC-1 细胞 , C643 细胞 , CAL-62 细胞 , 8305C 细胞 , KMH-2 细胞 , KHM-5M 细胞 , BHT101 细胞
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Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer (2023-06-19)
作者：Qingling Yuan:1.Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, 1# Jianshe East Road, Zhengzhou, Henan, China. yuanqingling113@163.com. ; Yuxia Fan:1.Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, 1# Jianshe East Road, Zhengzhou, Henan, China. ; Zheng Liu:1.Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, 1# Jianshe East Road, Zhengzhou, Henan, China. ; Xiaoming Wang:1.Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, 1# Jianshe East Road, Zhengzhou, Henan, China. ; Meng Jia:1.Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, 1# Jianshe East Road, Zhengzhou, Henan, China. ; Yongqiang Dong:1.Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, 1# Jianshe East Road, Zhengzhou, Henan, China. ; Zushi Geng:1.Department of Thyroid Surgery, The First Affiliated Hospital o
期刊：Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer
DOI：10.1007/s10495-023-01861-1
影响因子 ：7.2
引用产品： TPC-1 细胞 , 8305C 细胞 , BHT101 细胞 , CAL-62 细胞 , HTh-7 细胞
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Redox/pH-responsive hollow manganese dioxide nanoparticles for thyroid cancer treatment (2023-09-15)
作者：Jinren Liu:1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China. ; Changzhi Guo:1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China. ; Chunxiang Li:1.Department of Molecular Imaging, The First Affiliated Hospital of Qiqihar Medical University, Qiqihar, China. ; Qiushi Jia:1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China. ; Zhengrong Xie:1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China. ; 2.Department of Molecular Imaging, The First Affiliated Hospital of Qiqihar Medical University, Qiqihar, China. ; Ziyue Wang:1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China. ; Hongda Tian:1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China. ; Zhongyuan Li:1
期刊：Redox/pH-responsive hollow manganese dioxide nanoparticles for thyroid cancer treatment
DOI：10.3389/fchem.2023.1249472
影响因子 ：5.5
引用产品： 8305C 细胞
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pH-responsive MTX-BSA@MnO2-Cy5.5 for NIRF/MR imaging guided chemotherapy of anaplastic thyroid carcinoma (2023-09-17)
作者：Zhengrong Xie: 1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China; Qiushi Jia: 1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China; Shuang Wu: 1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China; Liguo Hao: 1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China; Jinren Liu: 1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China; Changzhi Guo: 1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China; Hongda Tian: 1.Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, China; Chunxiang Li: 1.Department of Molecular Imaging, The First Affiliated Hospital of Qiqihar Medical University, Qiqihar, China; Zhongyuan Li: 1.Departm
期刊：pH-responsive MTX-BSA@MnO2-Cy5.5 for NIRF/MR imaging guided chemotherapy of anaplastic thyroid carcinoma
DOI：10.1016/j.jddst.2023.104960
影响因子 ：5.0
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Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) Plays an Oncogenic Role in Thyroid Carcinoma by Activating the AKT and ERK1/2 Signaling Pathway (2023-07-01)
作者：Chen Peng:1.Otolaryngology Head and Neck Surgery Research Institute, Shanxi Medical University, Taiyuan, 030001, China. ; 2.Department of Head and Neck Surgery, Shanxi Province Cancer Hospital, Taiyuan, 030001, China. ; 3.Department of Head and Neck Surgery, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Taiyuan, 030001, China. ; 4.Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, 030001, China. ; Chunming Zhang:1.Otolaryngology Head and Neck Surgery Research Institute, Shanxi Medical University, Taiyuan, 030001, China. ; 2.Department of Otolaryngology Head and Neck Surgery, First Hospital of Shanxi Medical University, Taiyuan, 030001, China. ; 3.Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China. ; Wenjie Yu:1.Otolaryngology Head and Neck Surgery Research Institute, Shanxi Medical University, Taiyuan, 030001, China. ; 2.Department of Otolaryngology
期刊：Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) Plays an Oncogenic Role in Thyroid Carcinoma by Activating the AKT and ERK1/2 Signaling Pathway
DOI：10.2174/1568009623666230118111745
影响因子 ：3.0
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Tripartite motif containing 63, regulated by E26 transformation specific variant 4, facilitates the thyroid carcinoma progression and the AKT, p38, and ERK signaling pathways (2004-02-20)
作者：Jingni He:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110022, PR China. ; Ying Zhang:1.Department of Clinical Oncology, Shengjing Hospital of China Medical University, Shenyang, 110022, PR China. ; Baiyu Yao:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110022, PR China. ; Lidong Wang:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110022, PR China. ; Zhong Tian:1.Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110022, PR China. Electronic address: tianzhong@sj-hospital.org. ;
期刊：Tripartite motif containing 63, regulated by E26 transformation specific variant 4, facilitates the thyroid carcinoma progression and the AKT, p38, and ERK signaling pathways
影响因子 ：4.1
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