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产品概述
名称 | SV40 MES 13 (小鼠肾小球系膜细胞) (种属鉴定正确) |
别称 | SV40-MES13; MES-13; MES 13; MES13 |
种属 | 小鼠 |
生长特性 | 贴壁细胞 |
细胞形态 | 成纤维细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:8 |
推荐换液频率 | 2-3次/周 |
背景描述 | SV40 MES 13细胞的细胞骨架染色突出呈现肌动蛋白,在细胞质中有丰富的平行微丝。有报道称,在1uM血管紧张素Ⅱ存在下,SV40 MES 13细胞会收缩。SV40 MES 13细胞在软琼脂中形成克隆;SV40大T抗原阳性。 |
年龄(性别) | 7-10周龄 |
组织来源 | 肾小球系膜细胞 |
细胞类型 | 转化细胞系 |
生物安全等级 | BSL-2 |
倍增时间 | ~26 hours |
保藏机构 | ATCC; CRL-1927 |
STR鉴定
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STR位点信息
18-3 16 6-7 12 5-5 14,17 X-1 28 1-2 13,19 7-1 25.2 8-1 16 1-1 17 19-2 13 15-3 22.3 12-1 17 6-4 15.1 4-2 20.3 3-2 14 2-1 9,16 13-1 16.2,17.1
11-2 16 17-2 15 -
STR鉴定图
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参考文献
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tRF3-IleAAT reduced extracellular matrix synthesis in diabetic kidney disease mice by targeting ZNF281 and inhibiting ferroptosis (2024-01-29)
期刊:ACTA PHARMACOLOGICA SINICA
DOI:10.1038/s41401-024-01228-5
影响因子 :8.2
引用产品: SV40 MES 13 细胞
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Diminished nuclear-localized β-adrenoceptor signalling activates YAP to promote kidney fibrosis in diabetic nephropathy (2024-10-02)
期刊:BRITISH JOURNAL OF PHARMACOLOGY
影响因子 :6.8
引用产品: SV40 MES 13 细胞
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Integrative transcriptome analysis reveals Serpine2 promotes glomerular mesangial cell proliferation and extracellular matrix accumulation via activating ERK1/2 signalling pathway in diabetic nephropathy (2024-11-18)
期刊:DIABETES OBESITY & METABOLISM
影响因子 :5.4
引用产品: SV40 MES 13 细胞
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Puerarin alleviates the high glucose-induced oxidative stress via the RAGE/PKC/NOX4 axis in renal mesangial cells (2024-11-01)
期刊:JOURNAL OF TOXICOLOGICAL SCIENCES
影响因子 :1.8
引用产品: SV40 MES 13 细胞
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Huanglian Decoction treats Henoch-Schonlein purpura nephritis by inhibiting NF-κB/NLRP3 signaling pathway and reducing renal IgA deposition (2024-04-08)
期刊:ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
DOI:10.1590/0001-3765202420220970
影响因子 :1.3
引用产品: SV40 MES 13 细胞
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Circ-0000953 deficiency exacerbates podocyte injury and autophagy disorder by targeting Mir665-3p-Atg4b in diabetic nephropathy (2023-12-03)
期刊:Autophagy
DOI:10.1080/15548627.2023.2286128
影响因子 :13.3
引用产品: 小鼠肾小管上皮细胞 , SV40 MES 13 细胞 , 小鼠肾动脉内皮细胞
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ASH2L-mediated H3K4me3 drives diabetic nephropathy through HIPK2 and Notch1 pathway (2023-10-23)
期刊:Translational Research
DOI:10.1016/j.trsl.2023.10.002
影响因子 :7.8
引用产品: SV40 MES 13 细胞
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Seven new triterpenoid saponins from Astragalus membranaceus var. mongholicus and the inhibition of high-glucose induced SV40 MES 13 cells (2023-04-07)
期刊:NEW JOURNAL OF CHEMISTRY
影响因子 :3.3
引用产品: SV40 MES 13 细胞
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Cornuside inhibits glucose-induced proliferation and inflammatory response of mesangial cells (2023-11-01)
期刊:KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
DOI:10.4196/kjpp.2023.27.6.513
影响因子 :2.0
引用产品: SV40 MES 13 细胞
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ASH2L Aggravates Fibrosis and Inflammation through HIPK2 in High Glucose-Induced Glomerular Mesangial Cells (2022-11-29)
期刊:Genes
影响因子 :4.1
引用产品: SV40 MES 13 细胞
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LncRNA Dlx6os1 Accelerates Diabetic Nephropathy Progression by Epigenetically Repressing SOX6 via Recruiting EZH2 (2022-01-17)
期刊:Kidney Blood Press Res
影响因子 :2.8
引用产品: SV40 MES 13 细胞
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METTL3 enhances NSD2 mRNA stability to reduce renal impairment and interstitial fibrosis in mice with diabetic nephropathy (2022-03-30)
期刊:BMC Nephrology
DOI:10.1186/s12882-022-02753-3
影响因子 :2.3
引用产品: SV40 MES 13 细胞
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Targeting Mechanosensitive Piezo1 Alleviated Renal Fibrosis Through p38MAPK-YAP Pathway. (2021-11-05)
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.5
引用产品: SV40 MES 13 细胞
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CircSMAD4 alleviates high glucose-induced inflammation, extracellular matrix deposition and apoptosis in mouse glomerulus mesangial cells by relieving miR-377-3p-mediated BMP7 inhibition (2021-11-20)
期刊:Diabetology & Metabolic Syndrome
DOI:10.1186/s13098-021-00753-1
影响因子 :4.8
引用产品: SV40 MES 13 细胞
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Rosiglitazone attenuates high glucose-induced proliferation, inflammation, oxidative stress and extracellular matrix accumulation in mouse mesangial cells through the Gm26917/miR-185-5p pathway (2021-03-30)
期刊:Endocrine Journal
影响因子 :2.9
引用产品: SV40 MES 13 细胞 , DMEM高糖 培养基 , Ham's F-12 培养基 , 特级胎牛血清
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miR-1968-5p is involved in the pathogenesis of lupus nephritis of NZBWF1 mice by targeting csf1 (2021-07-06)
期刊:Clinical and Experimental Nephrology
DOI:10.1007/s10157-021-02091-y
影响因子 :2.3
引用产品: SV40 MES 13 细胞
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