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产品概述
名称 | T98G (人脑胶质瘤细胞) (STR鉴定正确) |
别称 | T 98 G; T-98G; T98 G; T98-G |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 成纤维细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:5 |
推荐换液频率 | 2-3次/周 |
背景描述 | When deprived of serum or when crowded, the cells enter a viable G1 arrested state. The cells are anchorage independent. |
年龄(性别) | 男性;61岁 |
组织来源 | 脑组织 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胶质瘤细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~28-40 hours |
保藏机构 | ATCC; CRL-1690 ECACC; 92090213 JCRB; IFO50303 JCRB; JCRB9041 KCLB; 21690 RCB; RCB1954 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,12 D2S1338 19,24 D3S1358 16 D5S818 10,12 D7S820 9,10 D8S1179 13,14 D13S317 13 D16S539 13 D18S51 13,16 D19S433 12 D21S11 28,32.2 FGA 21,22 PentaD 10,11 PentaE 16 TH01 7,9.3 TPOX 8 vWA 17,20 D6S1043 14 D12S391 17,18 D2S441 11 -
STR鉴定图
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参考文献
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Doxorubicin-loaded PEGylated liposome modified with ANGPT2-specific peptide for integrative glioma-targeted imaging and therapy (2025-01-04)
期刊:Materials Today Bio
DOI:10.1016/j.mtbio.2025.101455
影响因子 :8.7
引用产品: T98G 细胞 , T98G细胞专用培养基 , U251 细胞 , U-87 MG 细胞
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Hypoxia-driven M2-polarized macrophages facilitate the epithelial-mesenchymal transition of glioblastoma via extracellular vesicles (2024-10-07)
期刊:Theranostics
影响因子 :12.4
引用产品: LN229 [LN-229; LNT-229] 细胞 , U-118 MG 细胞 , U251 细胞 , T98G 细胞 , A172 细胞 , THP-1 细胞
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PEGylated Nanoliposomal Doxorubicin Conjugated with Specific TREM2 Peptides for Glioma-Targeting Therapy (2024-12-23)
期刊:Advanced Healthcare Materials
影响因子 :10.0
引用产品: T98G 细胞 , T98G细胞专用培养基 , U251 细胞 , U-87 MG 细胞
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Hsa_circ_0021205 enhances lipolysis via regulating miR-195-5p/HSL axis and drives malignant progression of glioblastoma (2024-02-10)
期刊:Cell Death Discovery
DOI:10.1038/s41420-024-01841-7
影响因子 :7.0
引用产品: SNB-19 细胞 , LN229 [LN-229; LNT-229] 细胞 , U251 细胞 , T98G 细胞 , U-87 MG 细胞
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Molecular mechanisms and diagnostic model of glioma-related epilepsy (2024-10-03)
期刊:npj Precision Oncology
DOI:10.1038/s41698-024-00721-8
影响因子 :6.8
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Prognosis and therapeutic significance of IGF-1R-related signaling pathway gene signature in glioma (2024-04-11)
期刊:Frontiers in Cell and Developmental Biology
DOI:10.3389/fcell.2024.1375030
影响因子 :5.5
引用产品: LN229 [LN-229; LNT-229] 细胞 , U251 细胞 , T98G 细胞
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The Liquid-Fermentation Formulation of Sanghuangporus sanghuang Optimized by Response Surface Methodology and Evaluation of Biological Activity of Extracellular Polysaccharides (2024-04-13)
期刊:Foods
影响因子 :5.2
引用产品: T98G 细胞 , U251 细胞 , HCT 116 细胞
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Cordycepin inhibits glioma growth by downregulating PD-L1 expression via the NOD-like receptor/NFKB1/STAT1 axis (2024-07-30)
期刊:CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 :4.7
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Machine learning unveils immune-related signature in multicenter glioma studies (2024-02-23)
期刊:iScience
DOI:10.1016/j.isci.2024.109317
影响因子 :4.6
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TBX15 facilitates malignant progression of glioma by transcriptional activation of TXDNC5 (2024-01-18)
期刊:iScience
DOI:10.1016/j.isci.2024.108950
影响因子 :4.6
引用产品: 人神经星形胶质细胞 , U-118 MG 细胞 , A172 细胞 , T98G 细胞 , LN229 [LN-229; LNT-229] 细胞 , U251 细胞 , THP-1 细胞
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TIFA enhances glycolysis through E2F1 and promotes the progression of glioma (2024-10-29)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2024.111498
影响因子 :4.4
引用产品: A172 细胞 , T98G 细胞 , LN229 [LN-229; LNT-229] 细胞 , U251 细胞
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C1GALT1 high expression enhances the progression of glioblastoma through the EGFR-AKT/ERK cascade (2024-11-17)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2024.111513
影响因子 :4.4
引用产品: U251 细胞 , U-87 MG 细胞 , T98G 细胞 , LN-18 细胞 , A172 细胞
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CBX2 enhances the progression and TMZ chemoresistance of glioma via EZH2-mediated epigenetic silencing of PTEN expression (2024-07-24)
期刊:Frontiers in Pharmacology
DOI:10.3389/fphar.2024.1430891
影响因子 :4.4
引用产品: T98G 细胞 , 青霉素-链霉素溶液(双抗),100× , A172 细胞 , DMEM高糖 培养基 , LN229 [LN-229; LNT-229] 细胞
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Pan-cancer analysis revealed prognosis value and immunological relevance of RAMPs (2024-01-18)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e24849
影响因子 :4.0
引用产品: T98G 细胞
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Phospholipid scramblase 1 acts through the IL-6/JAK/STAT3 pathway to promote the malignant progression of glioma (2024-04-16)
期刊:ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影响因子 :3.9
引用产品: A172 细胞 , T98G 细胞 , U251 细胞 , LN229 [LN-229; LNT-229] 细胞 , U-87 MG 细胞
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MiR-760 exerts a critical regulatory role in glioma proliferation, migration, and invasion by modulating MMP2 expression. (2024-04-08)
期刊:Journal of Cancer
影响因子 :3.9
引用产品: U-118 MG 细胞 , U-87 MG 细胞 , U251 细胞 , T98G 细胞
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Comprehensive pan-cancer analysis of ACSS3 as a biomarker for prognosis and immunotherapy response (2024-07-27)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e35231
影响因子 :3.4
引用产品: 人神经星形胶质细胞 , U251 细胞 , T98G 细胞 , LN229 [LN-229; LNT-229] 细胞 , U-87 MG 细胞
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EP300 regulates the SLC16A1-AS1-AS1/TCF3 axis to promote lung cancer malignancies through the Wnt signaling pathway (2024-03-07)
期刊:Heliyon
DOI:10.1016/j.heliyon.2024.e27727
影响因子 :3.4
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Optimization of Fermentation Culture Medium for Sanghuangporus alpinus Using Response-Surface Methodology (2024-05-06)
期刊:Horticulturae
DOI:10.3390/horticulturae10050474
影响因子 :3.1
引用产品: U251 细胞 , T98G 细胞 , HCT 116 细胞
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CENPA facilitates glioma stem cell stemness and suppress ferroptosis to accelerate glioblastoma multiforme by promoting GBP2 transcription (2024-06-28)
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.9
引用产品: U-87 MG 细胞 , T98G 细胞
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ZNF384 transcriptionally activated MGST1 to confer TMZ resistance of glioma cells by negatively regulating ferroptosis (2024-06-01)
期刊:CANCER CHEMOTHERAPY AND PHARMACOLOGY
DOI:10.1007/s00280-024-04681-5
影响因子 :2.7
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Regulation of a novel circATP8B4/miR-31-5p/nestin ceRNA crosstalk in proliferation, motility, invasion and radiosensitivity of human glioma cells (2024-09-17)
期刊:JOURNAL OF RADIATION RESEARCH
影响因子 :1.9
引用产品: T98G 细胞 , HMC3 细胞 , U251 细胞 , A172 细胞 , LN229 [LN-229; LNT-229] 细胞
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Arsenic Trioxide Induces Retinoic Acid-Related Orphan Receptor Beta and Blocks the WNT Pathway to Inhibit Stemness in Glioblastoma (2024-09-18)
期刊:TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
影响因子 :1.7
引用产品: T98G 细胞
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Oncolytic viruses engineered to enforce cholesterol efflux restore tumor-associated macrophage phagocytosis and anti-tumor immunity in glioblastoma (2023-07-20)
期刊:Nature Communications
DOI:10.1038/s41467-023-39683-z
影响因子 :16.6
引用产品: T98G 细胞
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Amifostine-Loaded Nanocarrier Traverses the Blood–Brain Barrier and Prevents Radiation-Induced Brain Injury (2023-03-14)
期刊:ACS Applied Materials & Interfaces
影响因子 :9.5
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Nifuroxazide inhibits the growth of glioblastoma and promotes the infiltration of CD8 T cells to enhance antitumour immunity (2023-03-14)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.109987
影响因子 :5.6
引用产品: LN229 [LN-229; LNT-229] 细胞 , U251 细胞 , T98G 细胞 , A172 细胞 , 人脐静脉内皮细胞 , GL261 细胞 , BV2 细胞
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A TGF-β signaling-related lncRNA signature for prediction of glioma prognosis, immune microenvironment, and immunotherapy response (2023-10-18)
期刊:CNS Neuroscience & Therapeutics
影响因子 :5.5
引用产品: T98G 细胞 , U251 细胞 , LN229 [LN-229; LNT-229] 细胞
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The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma. (2023-10-17)
期刊:Aging-US
影响因子 :5.2
引用产品: U-118 MG 细胞 , U251 细胞 , U-87 MG 细胞 , T98G 细胞 , LN229 [LN-229; LNT-229] 细胞 , SVG 细胞 , 293T [HEK-293T] 细胞
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Tumor-suppressive function and mechanism of miR-873-5p in glioblastoma: evidence based on bioinformatics analysis and experimental validation (2023-06-28)
期刊:Aging-US
影响因子 :5.2
引用产品: 293T [HEK-293T] 细胞 , T98G 细胞 , U251 细胞 , LN229 [LN-229; LNT-229] 细胞 , A172 细胞
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Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway (2023-06-02)
期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
DOI:10.1016/j.bbamcr.2023.119509
影响因子 :5.1
引用产品: A172 细胞 , U-87 MG 细胞 , U-118 MG 细胞 , U251 细胞 , T98G 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , MEM (含NEAA) 培养基
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Shikimate-Derived Meroterpenoids from the Ascidian-Derived Fungus Amphichorda felina SYSU-MS7908 and Their Anti-Glioma Activity (2023-11-15)
期刊:JOURNAL OF NATURAL PRODUCTS
DOI:10.1021/acs.jnatprod.3c00664
影响因子 :5.1
引用产品: T98G 细胞 , U-87 MG 细胞 , U251 细胞
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GD2 CAR-T cells in combination with Nivolumab exhibit enhanced antitumor efficacy (2023-03-24)
期刊:Translational Oncology
DOI:10.1016/j.tranon.2023.101663
影响因子 :5.0
引用产品: T98G 细胞 , U-87 MG 细胞 , U251 细胞 , A172 细胞
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Novel tumor necrosis factor-related long non-coding RNAs signature for risk stratification and prognosis in glioblastoma (2023-04-20)
期刊:Frontiers in Neurology
DOI:10.3389/fneur.2023.1054686
影响因子 :3.4
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miRNA-130a-3p/CPEB4 Axis Modulates Glioblastoma Growth and Progression (2023-12-21)
期刊:TECHNOLOGY IN CANCER RESEARCH & TREATMENT
影响因子 :2.8
引用产品: HA1800 细胞 , T98G 细胞 , U-87 MG 细胞
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Targeting the LINC00324/miR-16-5p/SEPT2 Signaling Cascade is Effective to Reverse Malignant Phenotypes in Glioblastoma (2023-08-01)
期刊:Anti-Cancer Agents in Medicinal Chemistry
DOI:10.2174/1871520623666230228122519
影响因子 :2.8
引用产品: A172 细胞 , T98G 细胞 , 293T [HEK-293T] 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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An association between ATP7B expression and human cancer prognosis and immunotherapy: a pan-cancer perspective (2023-11-30)
期刊:BMC Medical Genomics
DOI:10.1186/s12920-023-01714-5
影响因子 :2.7
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ADAMTS8 inhibits glioma development in vitro and in vivo (2023-07-14)
期刊:FOLIA NEUROPATHOLOGICA
影响因子 :2.0
引用产品: T98G 细胞 , U251 细胞 , U-87 MG 细胞
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Sphingosine kinase 1 promotes growth of glioblastoma by increasing inflammation mediated by the NF-κB /IL-6/STAT3 and JNK/PTX3 pathways (2022-09-29)
期刊:Acta Pharmaceutica Sinica B
DOI:10.1016/j.apsb.2022.09.012
影响因子 :14.9
引用产品: A172 细胞 , U-87 MG 细胞 , T98G 细胞 , U251 细胞 , 特级胎牛血清
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Profiling demethylase activity using epigenetically inactivated DNAzyme (2022-03-18)
期刊:Biosensors & Bioelectronics
DOI:10.1016/j.bios.2022.114186
影响因子 :12.6
引用产品: T98G 细胞 , U-87 MG 细胞 , 293T [HEK-293T] 细胞
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SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma (2022-12-24)
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-05526-w
影响因子 :9.7
引用产品: U-87 MG 细胞 , T98G 细胞 , LN229 [LN-229; LNT-229] 细胞 , U373 细胞 , HA1800 细胞 , THP-1 细胞
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The miR-145–MMP1 axis is a critical regulator for imiquimod-induced cancer stemness and chemoresistance (2022-03-28)
期刊:Pharmacological Research
DOI:10.1016/j.phrs.2022.106196
影响因子 :9.3
引用产品: U-87 MG 细胞 , T98G 细胞 , HCT 116 细胞
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RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12 (2022-11-15)
期刊:CNS Neuroscience & Therapeutics
影响因子 :7.0
引用产品: 人神经星形胶质细胞 , U251 细胞 , A172 细胞 , T98G 细胞 , LN229 [LN-229; LNT-229] 细胞 , U-118 MG 细胞 , THP-1 细胞
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CASP6 predicts poor prognosis in glioma and correlates with tumor immune microenvironment (2022-09-02)
期刊:Frontiers in Oncology
影响因子 :5.7
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EN1 Regulates Cell Growth and Proliferation in Human Glioma Cells via Hedgehog Signaling (2022-01-20)
期刊:International Journal Of Molecular Sciences
影响因子 :5.6
引用产品: U-118 MG 细胞 , U251 细胞 , A172 细胞 , U-87 MG 细胞 , T98G 细胞
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LINC01088 promotes the growth and invasion of glioma cells through regulating small nuclear ribonucleoprotein polypeptide A transcription (2022-04-07)
期刊:Bioengineered.
DOI:10.1080/21655979.2022.2051786
影响因子 :4.9
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A novel hypoxia-driven gene signature that can predict the prognosis and drug resistance of gliomas. (2022-09-02)
期刊:Frontiers in Genetics
影响因子 :4.8
引用产品: A172 细胞 , T98G 细胞 , U-87 MG 细胞
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Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway (2022-02-12)
期刊:Environmental Toxicology
影响因子 :4.1
引用产品: A172 细胞 , T98G 细胞 , U-87 MG 细胞 , U-118 MG 细胞
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CircRNA circ_POSTN promotes the malignancy of glioma by regulating the miR-433-3p/SPARC axis (2022-12-01)
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-022-01126-x
影响因子 :3.7
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EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR (2022-01-17)
期刊:Metabolic Brain Disease
DOI:10.1007/s11011-021-00899-x
影响因子 :3.6
引用产品: U251 细胞 , U-87 MG 细胞 , T98G 细胞 , A172 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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Identification of pimavanserin tartrate as a potent Ca2+-calcineurin-NFAT pathway inhibitor for glioblastoma therapy (2021-08-06)
期刊:Acta Pharmacologica Sinica
DOI:10.1038/s41401-021-00724-2
影响因子 :8.2
引用产品: U-87 MG 细胞 , U-118 MG 细胞 , A172 细胞 , T98G 细胞 , LN229 [LN-229; LNT-229] 细胞 , MCF 10A 细胞
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E2F2 drives glioma progression via PI3K/AKT in a PFKFB4-dependent manner (2021-03-24)
期刊:Life Sciences
影响因子 :6.8
引用产品: SHG-44 细胞 , U251 细胞 , A172 细胞 , T98G 细胞 , DMEM高糖 培养基
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ITGB3BP is a potential biomarker associated with poor prognosis of glioma (2021-12-24)
期刊:Journal of Cellular and Molecular Medicine
影响因子 :5.3
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Sevoflurane inhibits progression of glioma via regulating the HMMR antisense RNA 1/microRNA-7/cyclin dependent kinase 4 axis (2021-08-31)
期刊:Bioengineered
DOI:10.1080/21655979.2021.1976712
影响因子 :4.9
引用产品: LN229 [LN-229; LNT-229] 细胞 , T98G 细胞 , A172 细胞
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The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells (2021-11-18)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: U-87 MG 细胞 , LN229 [LN-229; LNT-229] 细胞 , U251 细胞 , T98G 细胞
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Enzyme-instructed supramolecular assemblies promote intracellular boron accumulation for boron neutron capture therapy (2021-08-04)
期刊:Nanotechnology
影响因子 :4.0
引用产品: T98G 细胞
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CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis (2021-10-09)
期刊:Bmc Cancer
DOI:10.1186/s12885-021-08803-7
影响因子 :3.8
引用产品: SHG-44 细胞 , U251 细胞 , LN229 [LN-229; LNT-229] 细胞 , A172 细胞 , T98G 细胞
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CKAP2L, as an Independent Risk Factor, Closely Related to the Prognosis of Glioma (2021-09-28)
期刊:Biomed Research International
影响因子 :3.4
引用产品: 人神经星形胶质细胞 , LN229 [LN-229; LNT-229] 细胞 , T98G 细胞 , U251 细胞 , A172 细胞
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Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway (2021-07-23)
期刊:3 BIOTECH
DOI:10.1007/s13205-021-02922-5
影响因子 :2.8
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CircTTBK2 Contributes to the Progression of Glioma Through Regulating miR-145-5p/CPEB4 Axis (2020-09-08)
期刊:Cancer Management and Research
影响因子 :3.3
引用产品: T98G 细胞 , LN229 [LN-229; LNT-229] 细胞
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