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产品概述
名称 | A172 (人胶质母细胞瘤细胞) (STR鉴定正确) |
别称 | A172; A 172; A-172 MG; A-172MG |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 成纤维细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
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推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | A172细胞在半固体培养基中可形成克隆;A172细胞在免疫抑制小鼠中不成瘤。 |
年龄(性别) | 男性;53岁 |
组织来源 | 脑;胶质母细胞瘤 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胶质瘤细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~40 hours |
致瘤性 | No, the cells were not tumorigenic in immunosuppressed mice.Yes, form colonies in semisolid medium. |
保藏机构 | ATCC; CRL-1620 ATCC; CRL-7899ECACC; 88062428 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 9,12 D2S1338 20,21 D3S1358 14,18 D5S818 11,12 D7S820 11 D8S1179 13,14 D13S317 11 D16S539 12 D18S51 12,13 D19S433 12,15.2 D21S11 28,32.2 FGA 20,22 PentaD 9,13 PentaE 5,10 TH01 6,9.3 TPOX 8,11 vWA 20 D6S1043 13,18 D12S391 22 D2S441 10,11 -
STR鉴定图
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参考文献
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YTHDF1 promotes the viability and self‑renewal of glioma stem cells by enhancing LINC00900 stability (2024-03-28)
期刊:INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子 :5.2
引用产品: A172 细胞
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DNA Damage-Induced Apoptosis Suppressor Triggers Progression and Stemness of Glioma by Enhancing Lymphoid Enhancer-Binding Factor 1 Expression (2024-03-21)
期刊:World Journal of Oncology
影响因子 :5.2
引用产品: U251 细胞 , U-87 MG 细胞 , A172 细胞 , U-118 MG 细胞
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Bioinformatics Analysis and Experimental Validation for Exploring Key Molecular Markers for Glioblastoma (2024-03-06)
期刊:APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
DOI:10.1007/s12010-024-04894-7
影响因子 :3.0
引用产品: 人神经星形胶质细胞 , U251 细胞 , U-87 MG 细胞 , A172 细胞
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PSMC2 promotes glioma progression by regulating immune microenvironment and PI3K/AKT/mTOR pathway (2024-03-30)
期刊:IMMUNOBIOLOGY
DOI:10.1016/j.imbio.2024.152802
影响因子 :2.8
引用产品: 人神经少突胶质细胞 , U251 细胞 , U-87 MG 细胞 , A172 细胞
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Silibinin suppresses glioblastoma cell growth, invasion, stemness, and glutamine metabolism by YY1/SLC1A5 pathway (2024-02-24)
期刊:Translational Neuroscience
影响因子 :2.1
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Screening and anti-glioma activity of Chiloscyllium plagiosum anti-human IL-13Rα2 single-domain antibody (2023-05-15)
期刊:IMMUNOLOGY
影响因子 :6.4
引用产品: A172 细胞
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Nifuroxazide inhibits the growth of glioblastoma and promotes the infiltration of CD8 T cells to enhance antitumour immunity (2023-03-14)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.109987
影响因子 :5.6
引用产品: LN229 [LN-229; LNT-229] 细胞 , U251 细胞 , T98G 细胞 , A172 细胞 , 人脐静脉内皮细胞 , GL261 细胞 , BV2 细胞
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Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway (2023-06-02)
期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
DOI:10.1016/j.bbamcr.2023.119509
影响因子 :5.1
引用产品: A172 细胞 , U-87 MG 细胞 , U-118 MG 细胞 , U251 细胞 , T98G 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , MEM (含NEAA) 培养基
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GD2 CAR-T cells in combination with Nivolumab exhibit enhanced antitumor efficacy (2023-03-24)
期刊:Translational Oncology
DOI:10.1016/j.tranon.2023.101663
影响因子 :5.0
引用产品: T98G 细胞 , U-87 MG 细胞 , U251 细胞 , A172 细胞
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CKAP4-mediated activation of FOXM1 via phosphorylation pathways regulates malignant behavior of glioblastoma cells (2023-01-24)
期刊:Translational Oncology
DOI:10.1016/j.tranon.2023.101628
影响因子 :5.0
引用产品: A172 细胞
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β3GNT9 as a prognostic biomarker in glioblastoma and its association with glioblastoma immune infiltration, migration and invasion (2023-09-12)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: 人神经星形胶质细胞 , A172 细胞 , U-87 MG 细胞 , U251 细胞
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Circular RNA circ_0000741/miR-379-5p/TRIM14 signaling axis promotes HDAC inhibitor (SAHA) tolerance in glioblastoma (2023-03-11)
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-023-01184-9
影响因子 :3.6
引用产品: A172 细胞 , U251 细胞 , A172细胞专用培养基 , U251细胞专用培养基
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Targeting the LINC00324/miR-16-5p/SEPT2 Signaling Cascade is Effective to Reverse Malignant Phenotypes in Glioblastoma (2023-08-01)
期刊:Anti-Cancer Agents in Medicinal Chemistry
DOI:10.2174/1871520623666230228122519
影响因子 :2.8
引用产品: A172 细胞 , T98G 细胞 , 293T [HEK-293T] 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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Low Expression of GRM4 Is Associated with Poor Prognosis and Tumor Immune Infiltration in Glioma (2023-12-19)
期刊:INTERNATIONAL JOURNAL OF NEUROSCIENCE
DOI:10.1080/00207454.2023.2297646
影响因子 :2.2
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Sphingosine kinase 1 promotes growth of glioblastoma by increasing inflammation mediated by the NF-κB /IL-6/STAT3 and JNK/PTX3 pathways (2022-09-29)
期刊:Acta Pharmaceutica Sinica B
DOI:10.1016/j.apsb.2022.09.012
影响因子 :14.9
引用产品: A172 细胞 , U-87 MG 细胞 , T98G 细胞 , U251 细胞 , 特级胎牛血清
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Chitinase-3 like-protein-1 promotes glioma progression via the NF-κB signaling pathway and tumor microenvironment reprogramming (2022-10-03)
期刊:Theranostics
影响因子 :11.6
引用产品: U-87 MG 细胞 , U251 细胞 , U-118 MG 细胞 , A172 细胞
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RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12 (2022-11-15)
期刊:CNS Neuroscience & Therapeutics
影响因子 :7.0
引用产品: 人神经星形胶质细胞 , U251 细胞 , A172 细胞 , T98G 细胞 , LN229 [LN-229; LNT-229] 细胞 , U-118 MG 细胞 , THP-1 细胞
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EN1 Regulates Cell Growth and Proliferation in Human Glioma Cells via Hedgehog Signaling (2001-02-20)
期刊:International Journal Of Molecular Sciences
影响因子 :5.6
引用产品: U-118 MG 细胞 , U251 细胞 , A172 细胞 , U-87 MG 细胞 , T98G 细胞
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Prognostic Significance of mRNA Expression RBBP8 or Its Methylation in Gliomas (2002-02-20)
期刊:Cellular And Molecular Neurobiology
DOI:10.1007/s10571-022-01198-4
影响因子 :4.2
引用产品: A172 细胞
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Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway (2002-02-20)
期刊:Environmental Toxicology
影响因子 :4.1
引用产品: A172 细胞 , T98G 细胞 , U-87 MG 细胞 , U-118 MG 细胞
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CircRNA circ_POSTN promotes the malignancy of glioma by regulating the miR-433-3p/SPARC axis (2022-12-01)
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-022-01126-x
影响因子 :3.7
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Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma (2022-10-27)
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-022-01069-3
影响因子 :3.7
引用产品: A172 细胞 , U251 细胞 , 人神经星形胶质细胞 , 人神经星形胶质细胞完全培养基
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EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR (2001-02-20)
期刊: Metabolic Brain Disease
DOI:10.1007/s11011-021-00899-x
影响因子 :3.6
引用产品: U251 细胞 , U-87 MG 细胞 , T98G 细胞 , A172 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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Identification of pimavanserin tartrate as a potent Ca2+-calcineurin-NFAT pathway inhibitor for glioblastoma therapy (2008-01-20)
期刊:Acta Pharmacologica Sinica
DOI:10.1038/s41401-021-00724-2
影响因子 :8.2
引用产品: U-87 MG 细胞 , U-118 MG 细胞 , A172 细胞 , T98G 细胞 , LN229 [LN-229; LNT-229] 细胞 , MCF 10A 细胞
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E2F2 drives glioma progression via PI3K/AKT in a PFKFB4-dependent manner (2003-01-20)
期刊:Life Sciences
影响因子 :6.8
引用产品: SHG-44 细胞 , U251 细胞 , A172 细胞 , T98G 细胞 , DMEM高糖 培养基
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CircRFX3 contributes to glioma progression through the circRFX3-miR-1179/miR-1229-VASP axis (2011-01-20)
期刊:Cancer Cell International
DOI:10.1186/s12935-021-02293-0
影响因子 :5.8
引用产品: SHG-44 细胞 , A172 细胞 , U251 细胞 , PaTu 8988t 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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Overexpressed XRCC2 as an independent risk factor for poor prognosis in glioma patients (2005-01-20)
期刊:Molecular Medicine
DOI:10.1186/s10020-021-00316-0
影响因子 :5.7
引用产品: HA 细胞 , Marcus 细胞 细胞 , A172 细胞 , U251 细胞
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Overexpression of GINS4 is associated with poor prognosis and survival in glioma patients (2009-01-20)
期刊:Molecular Medicine
DOI:10.1186/s10020-021-00378-0
影响因子 :5.7
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ITGB3BP is a potential biomarker associated with poor prognosis of glioma (2021-12-24)
期刊:Journal of Cellular and Molecular Medicine
影响因子 :5.3
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Sevoflurane inhibits progression of glioma via regulating the HMMR antisense RNA 1/microRNA-7/cyclin dependent kinase 4 axis (2008-01-20)
期刊:Bioengineered
DOI:10.1080/21655979.2021.1976712
影响因子 :4.9
引用产品: LN229 [LN-229; LNT-229] 细胞 , T98G 细胞 , A172 细胞
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CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis (2010-01-20)
期刊:Bmc Cancer
DOI:10.1186/s12885-021-08803-7
影响因子 :3.8
引用产品: SHG-44 细胞 , U251 细胞 , LN229 [LN-229; LNT-229] 细胞 , A172 细胞 , T98G 细胞
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Circular RNA circ_0001588 sponges miR-211-5p to facilitate the progression of glioblastoma via up-regulating YY1 expression (2007-01-20)
期刊:Journal Of Gene Medicine
DOI:10.1002/jgm.3371
影响因子 :3.5
引用产品: SHG-44 细胞 , A172 细胞 , U251 细胞 , U-87 MG 细胞 , 人神经星形胶质细胞
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CircFOXM1 promotes the proliferation, migration, invasion, and glutaminolysis of glioblastoma by regulating the miR-577/E2F5 axis (2006-01-20)
期刊:Bosnian Journal of Basic Medical Sciences
影响因子 :3.4
引用产品: 青霉素-链霉素溶液 (双抗),100× , U251 细胞 , LN229 [LN-229; LNT-229] 细胞 , A172 细胞 , 人神经星形胶质细胞
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Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway (2007-01-20)
期刊:3 BIOTECH
DOI:10.1007/s13205-021-02922-5
影响因子 :2.8
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