产品中心Cell Resources
联系我们CONTACT US
400-999-210024小时服务热线
产品概述
| 名称 | HMC3 (人小胶质细胞) (STR鉴定正确) |
| 别称 | Human Microglia Clone 3 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:8 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | The HMC3 cell line was established through SV40-dependent immortalization of a human fetal brain-derived primary microglia culture. |
| 年龄（性别） | 胚胎 |
| 组织来源 | 脑组织 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-2 |
| 保藏机构 | ATCC; CRL-3304 |
STR鉴定
-
STR位点信息
Amelogenin X CSF1PO 10,11 D2S1338 17,25 D3S1358 16,18 D5S818 11,12 D7S820 9,11 D8S1179 13,14 D13S317 11 D16S539 12,13 D18S51 18 D19S433 15,15.2 D21S11 30,31.2 FGA 21,25 PentaD 10,14 PentaE 7,13 TH01 6 TPOX 8,9 vWA 17,19 D6S1043 11 D12S391 16,21 D2S441 11,11.3 -
STR鉴定图
-
参考文献
-
Super-enhancer-driven LIF promotes the mesenchymal transition in glioblastoma by activating ITGB2 signaling feedback in microglia (2024-03-30)
期刊：NEURO-ONCOLOGY
影响因子 ：15.9
引用产品： LN229 [LN-229; LNT-229] 细胞 , SF126 细胞 , U-87 MG 细胞 , HMC3 细胞 , BV2 细胞
-
Microglia-endothelial cross-talk regulates diabetes-induced retinal vascular dysfunction through remodeling inflammatory microenvironment (2024-02-06)
期刊：iScience
DOI：10.1016/j.isci.2024.109145
影响因子 ：5.8
引用产品： HMC3 细胞
-
A New Modulator of Neuroinflammation in Diabetic Retinopathy: USP25 (2024-03-04)
期刊：INFLAMMATION
DOI：10.1007/s10753-024-01991-x
影响因子 ：5.1
-
Blood–brain barrier injury and neuroinflammation induced by SARS-CoV-2 in a lung–brain microphysiological system (2023-06-22)
期刊：Nature Biomedical Engineering
DOI：10.1038/s41551-023-01054-w
影响因子 ：28.1
引用产品： HULEC-5a 细胞 , HULEC-5a细胞专用培养基 , HMC3 细胞 , MEM (含NEAA) 培养基
-
Nanoplastic Stimulates the Amyloidogenesis of Parkinson's Alpha-Synuclein NACore (2023-11-21)
期刊：Small
影响因子 ：13.3
引用产品： HMC3 细胞 , HMC3细胞专用培养基
-
Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination (2023-03-25)
期刊：Journal of Neuroinflammation
DOI：10.1186/s12974-023-02764-3
影响因子 ：9.3
引用产品： HMC3 细胞 , MEM完全培养基 (含10%FBS）
-
α-Synuclein Induces Neuroinflammation Injury through the IL6ST-AS/STAT3/HIF-1α Axis (2023-01-11)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.6
引用产品： HMC3 细胞 , SH-SY5Y [SHSY-5Y] 细胞
-
Parthenolide alleviates microglia‐mediated neuroinflammation via MAPK/TRIM31/NLRP3 signaling to ameliorate cognitive disorder (2023-05-12)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110287
影响因子 ：5.6
-
BAFF deficiency aggravated optic nerve crush-induced retinal ganglion cells damage by regulating apoptosis and neuroinflammation via NF-κB-IκBα signaling (2023-12-04)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.111287
影响因子 ：5.6
引用产品： HMC3 细胞
-
Htr2b Promotes M1 Microglia Polarization and Neuroinflammation after Spinal Cord Injury via Inhibition of Neuregulin-1/ErbB Signaling (2023-09-25)
期刊：MOLECULAR NEUROBIOLOGY
DOI：10.1007/s12035-023-03656-6
影响因子 ：5.1
-
Daphnetin Improves Neuropathic Pain by Inhibiting the Expression of Chemokines and Inflammatory Factors in the Spinal Cord and Interfering with Glial Cell Polarization (2023-02-06)
期刊：Pharmaceuticals
影响因子 ：4.6
-
Exploring the Therapeutic Effects of Multifunctional N-Salicylic Acid Tryptamine Derivative against Parkinson’s Disease (2023-07-28)
期刊：ACS Omega
影响因子 ：4.1
引用产品： SH-SY5Y [SHSY-5Y] 细胞 , HMC3 细胞
-
Elevated LILRB1 expression predicts poor prognosis and is associated with tumor immune infiltration in patients with glioma (2023-05-04)
期刊：BMC CANCER
DOI：10.1186/s12885-023-10906-2
影响因子 ：3.8
引用产品： HMC3 细胞
-
Triptolide improves Alzheimer's disease by regulating the NF‑κB signaling pathway through the lncRNA NEAT1/microRNA 361‑3p/TRAF2 axis (2023-08-01)
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.7
引用产品： HMC3 细胞
-
Microglia increase CEMIP expression and promote brain metastasis in breast cancer through the JAK2/STAT3 signaling pathway (2023-11-21)
期刊：Oncologie
DOI：10.1515/oncologie-2023-0312
影响因子 ：0.9
引用产品： HMC3 细胞
-
Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line (2022-09-23)
期刊：ENVIRONMENTAL POLLUTION
DOI：10.1016/j.envpol.2022.120217
影响因子 ：10.0
引用产品： HMC3 细胞 , HMC3细胞专用培养基
-
lncRNA SND1-IT1 delivered via intracerebral hemorrhage-derived exosomes affect the growth of human microglia by regulating the miR-124-3p/MTF1 axis (2022-12-22)
期刊：JOURNAL OF CELLULAR PHYSIOLOGY
影响因子 ：6.5
引用产品： HMC3 细胞
-
TMEM16F may be a new therapeutic target for Alzheimer’s disease (2022-08-02)
期刊：Neural Regeneration Research
影响因子 ：6.1
引用产品： HMC3 细胞 , MEM (含NEAA) 培养基 , 特级胎牛血清 , DMEM低糖 (不含酚红) 培养基
-
Iron oxide nanoparticles loaded with paclitaxel inhibits glioblastoma by enhancing autophagy-dependent ferroptosis pathway (2003-02-20)
期刊：European Journal Of Pharmacology
DOI：10.1016/j.ejphar.2022.174860
影响因子 ：5.0
引用产品： HMC3 细胞
-
LINC01088 promotes the growth and invasion of glioma cells through regulating small nuclear ribonucleoprotein polypeptide A transcription (2004-02-20)
期刊：Bioengineered.
DOI：10.1080/21655979.2022.2051786
影响因子 ：4.9
-
lncRNA MSC-AS1 Aggravates Diabetic Nephropathy by Regulating the miR-325/CCNG1 Axis (2001-02-20)
期刊：Journal of Healthcare Engineering
影响因子 ：0.0
引用产品： 人肾小球系膜细胞完全培养基 , HMC3 细胞
-
Circ-FBXW12 aggravates the development of diabetic nephropathy by binding to miR-31-5p to induce LIN28B (2012-01-20)
期刊：Diabetology & Metabolic Syndrome
DOI：10.1186/s13098-021-00757-x
影响因子 ：4.8
引用产品： HMC细胞专用培养基 , HMC3 细胞
-
Amorfrutins Relieve Neuropathic Pain through the PPARγ/CCL2 Axis in CCI Rats (2001-01-20)
期刊：PPAR Research
影响因子 ：2.9
引用产品： HMC3 细胞
FAQs
Q：{{item.question}}
A：
产品资料
识别码示意图
