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产品概述
| 名称 | BRL 3A (大鼠肝细胞) (种属鉴定正确) |
| 别称 | BRL3A; BRL 3A; Buffalo Rat Liver-3A |
| 种属 | 大鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 成纤维细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | BRL 3A细胞的无血清条件培养基是MSA的一个来源，MSA多肽家族能够部分满足鸡胚成纤维细胞对血清的需求。 |
| 组织来源 | 肝 |
| 细胞类型 | 自发永生化细胞 |
| 生物安全等级 | BSL-1 |
| 基因表达情况 | Somatomedin like multiplication stimulating activity (MSA) |
| 保藏机构 | ATCC; CRL-1442 BCRC; 60218 ECACC; 85111503 |
种属鉴定
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种属鉴定图
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参考文献
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Effects of pesticide dichlorvos on liver injury in rats and related toxicity mechanisms (2025-01-16)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2025.117747
影响因子 ：6.2
引用产品： BRL 3A 细胞
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Rutaecarpine alleviates hepatic ischemia‒reperfusion injury in liver transplantation by inhibiting inflammatory response and oxidative stress (2025-02-03)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2025.1539744
影响因子 ：4.4
引用产品： BRL 3A 细胞
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Bioreactor-based stem cell therapy for liver fibrosis (2024-03-05)
期刊：Biofabrication
影响因子 ：9.0
引用产品： BRL 3A 细胞
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Theaflavins mitigate diabetic symptoms in GK rats by modulating the INSR/PI3K-Akt/GSK-3 pathway and intestinal microbiota (2024-07-31)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.134331
影响因子 ：7.7
引用产品： BRL 3A 细胞
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Investigating the inhibition of xanthine oxidase by five catechins: Kinetic studies, spectroscopy, molecular docking, and dynamics simulations (2024-10-03)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.136231
影响因子 ：7.7
引用产品： BRL 3A 细胞
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Berberine alleviates fructose-induced hepatic injury via ADK/AMPK/Nrf2 pathway: A novel insight (2024-09-08)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.117361
影响因子 ：6.9
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Enhancing Chemotherapy Efficacy via an Autologous Erythrocyte-Anchoring Strategy with a Closed-System Drug-Transfer Device (2024-12-18)
期刊：ACS Biomaterials Science & Engineering
DOI：10.1021/acsbiomaterials.4c02128
影响因子 ：5.4
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Poria cocos polysaccharides improve alcoholic liver disease by interfering with ferroptosis through NRF2 regulation (2024-03-20)
期刊：Aging-US
影响因子 ：3.9
引用产品： BRL 3A 细胞
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17β-Estradiol protects female rats from bilateral oophorectomy-induced nonalcoholic fatty liver disease induced by improving linoleic acid metabolism alteration and gut microbiota disturbance (2024-04-03)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e29013
影响因子 ：3.4
引用产品： BRL 3A 细胞
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Protective effect of quercetin against macrophage-mediated hepatocyte injury via anti-inflammation, anti-apoptosis and inhibition of ferroptosis (2024-05-09)
期刊：AUTOIMMUNITY
DOI：10.1080/08916934.2024.2350202
影响因子 ：3.3
引用产品： J774A.1 细胞 , BRL 3A 细胞
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Data mining-guided alleviation of hyperuricemia by Paeonia veitchii Lynch through inhibition of xanthine oxidase and regulation of renal urate transporters (2023-12-19)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2023.155305
影响因子 ：7.9
引用产品： BRL 3A 细胞
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17β-Estradiol (E2) Upregulates the ERα/SIRT1/PGC-1α Signaling Pathway and Protects Mitochondrial Function to Prevent Bilateral Oophorectomy (OVX)-Induced Nonalcoholic Fatty Liver Disease (NAFLD) (2023-12-12)
期刊：Antioxidants
影响因子 ：7.0
引用产品： BRL 3A 细胞
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Zanthoxylum armatum DC fruit ethyl acetate extract site induced hepatotoxicity by activating endoplasmic reticulum stress and inhibiting autophagy in BRL-3A models (2023-10-05)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
引用产品： BRL 3A 细胞 , BRL 3A细胞专用培养基
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Hepatoprotective Effect of Tea Composite Solid Beverage on Alcohol-Caused Rat Liver Injury (2023-11-14)
期刊：Foods
影响因子 ：5.2
引用产品： BRL 3A 细胞
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Hypothermic machine perfusion reduces donation after circulatory death liver ischemia–reperfusion injury through the SERPINA3-mediated PI3Kδ/Akt pathway (2023-12-22)
期刊：Human Cell
DOI：10.1007/s13577-023-01012-3
影响因子 ：4.3
引用产品： BRL 3A 细胞
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Transcriptomic analysis of hepatocytes reveals the association between ubiquitin-specific peptidase 1 and yes-associated protein 1 during liver regeneration (2023-07-21)
期刊：Regenerative Therapy
DOI：10.1016/j.reth.2023.07.004
影响因子 ：4.3
引用产品： BRL 3A 细胞
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Enhanced US/CT/MR imaging of integrin αvβ3 for liver fibrosis staging in rat (2022-10-03)
期刊：Frontiers in Chemistry
影响因子 ：5.6
引用产品： BRL 3A 细胞
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Ginseng polysaccharide attenuates red blood cells oxidative stress injury by regulating red blood cells glycolysis and liver gluconeogenesis (2022-09-16)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.2
引用产品： BRL 3A 细胞
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Zanthoxylum armatum DC. extract induces liver injury via autophagy suppression and oxidative damage by activation of mTOR/ULK1 pathway (2022-08-14)
期刊：TOXICON
DOI：10.1016/j.toxicon.2022.08.008
影响因子 ：3.0
引用产品： BRL 3A 细胞 , BRL细胞专用培养基
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Tissue-Specific Hydrogels Ameliorate Hepatic Ischemia/Reperfusion Injury in Rats by Regulating Macrophage Polarization via TLR4/NF-κB Signaling (2021-03-08)
期刊：ACS Biomaterials Science & Engineering
DOI：10.1021/acsbiomaterials.0c01610
影响因子 ：5.8
引用产品： BRL 3A 细胞
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Activation of ATM/Chk2 by Zanthoxylum armatum DC extract induces DNA damage and G1/S phase arrest in BRL 3A cells. (2021-11-12)
期刊：Journal Of Ethnopharmacology
影响因子 ：5.4
引用产品： BRL 3A 细胞
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Hydrolyzed camel whey protein alleviated heat stress-induced hepatocyte damage by activated Nrf2/HO-1 signaling pathway and inhibited NF-κB/NLRP3 axis (2021-01-06)
期刊：Cell Stress & Chaperones
DOI：10.1007/s12192-020-01184-z
影响因子 ：3.8
引用产品： BRL 3A 细胞
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Comparison of bone marrow?vs. adipose tissue?derived mesenchymal stem cells for attenuating liver fibrosis (2017-10-18)
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.7
引用产品： BRL 3A 细胞
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Ultrasound molecular imaging with cRGD-PLGA-PFOB nanoparticles for liver fibrosis staging in a rat model (2017-09-28)
期刊：Oncotarget
影响因子 ：0.0
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