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产品概述
名称 | BRL 3A (大鼠肝细胞) (种属鉴定正确) |
别称 | BRL3A; BRL 3A; Buffalo Rat Liver-3A |
种属 | 大鼠 |
生长特性 | 贴壁细胞 |
细胞形态 | 成纤维细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
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推荐传代比例 | 1:3-1:6 |
推荐换液频率 | 2-3次/周 |
背景描述 | BRL 3A细胞的无血清条件培养基是MSA的一个来源,MSA多肽家族能够部分满足鸡胚成纤维细胞对血清的需求。 |
组织来源 | 肝 |
细胞类型 | 自发永生化细胞 |
生物安全等级 | BSL-1 |
基因表达情况 | Somatomedin like multiplication stimulating activity (MSA) |
保藏机构 | ATCC; CRL-1442 BCRC; 60218 ECACC; 85111503 |
种属鉴定
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种属鉴定图
参考文献
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Bioreactor-based stem cell therapy for liver fibrosis (2024-03-05)
作者:Mengchao Yan:1.Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, People's Republic of China. ; 2.The Medical School, Lanzhou University, Lanzhou 730000, People's Republic of China. ; Jia Yao:1.The Medical School, Lanzhou University, Lanzhou 730000, People's Republic of China. ; 2.Key Laboratory of Biotherapy and Regenerative Medicine of Gansu Province, Lanzhou 730000, People's Republic of China. ; Ye Xie:1.The Medical School, Lanzhou University, Lanzhou 730000, People's Republic of China. ; Pan Jiang:1.State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, People's Republic of China. ; Jun Yan:1.Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, People's Republic of China. ; 2.The Medical School, Lanzhou University, Lanzhou 730000, People's Republic of China. ; 3.Key Laboratory of Biotherapy and Regenerative Medicine of Gansu Province,
期刊:Bioreactor-based stem cell therapy for liver fibrosis
影响因子 :9.0
引用产品: BRL 3A 细胞
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17β-Estradiol (E2) Upregulates the ERα/SIRT1/PGC-1α Signaling Pathway and Protects Mitochondrial Function to Prevent Bilateral Oophorectomy (OVX)-Induced Nonalcoholic Fatty Liver Disease (NAFLD) (2023-12-12)
作者:Ying Tian:1.Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College Hospital (Dongdan Campus), No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing 100730, China. ; Xinyu Hong:1.Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College Hospital (Dongdan Campus), No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing 100730, China. ; Yuan Xie:1.Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College Hospital (Dongd
期刊:17β-Estradiol (E2) Upregulates the ERα/SIRT1/PGC-1α Signaling Pathway and Protects Mitochondrial Function to Prevent Bilateral Oophorectomy (OVX)-Induced Nonalcoholic Fatty Liver Disease (NAFLD)
影响因子 :7.0
引用产品: BRL 3A 细胞
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Hepatoprotective Effect of Tea Composite Solid Beverage on Alcohol-Caused Rat Liver Injury (2023-11-14)
作者:Zheng Tang:1.National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha 410128, China. ; 2.Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, China. ; 3.Collaborative Innovation Centre of Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha 410128, China. ; Li Zhan:1.National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha 410128, China. ; 2.Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, China. ; 3.Collaborative Innovation Centre of Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha 410128, China. ; Ranran He:1.National Research Center of Engineering Technology for Utilization of Functional Ingredients from Bot
期刊:Hepatoprotective Effect of Tea Composite Solid Beverage on Alcohol-Caused Rat Liver Injury
影响因子 :5.2
引用产品: BRL 3A 细胞
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Hypothermic machine perfusion reduces donation after circulatory death liver ischemia–reperfusion injury through the SERPINA3-mediated PI3Kδ/Akt pathway (2023-12-22)
作者:Sheng Peng:1.Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, National Quality Control Center for Donated Organ Procurement, Hubei Key Laboratory of Medical Technology on Transplantation, Hubei Clinical Research Center for Natural Polymer Biological Liver, Hubei Engineering Center of Natural Polymer-Based Medical Materials, Zhongnan Hospital of Wuhan University, Wuhan, 430071, Hubei, China. ; 2.Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. ; Wenjin Liang:1.Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, National Quality Control Center for Donated Organ Procurement, Hubei Key Laboratory of Medical Technology on Transplantation, Hubei Clinical Research Center for Natural Polymer Biological Liver, Hubei Engineering Center of Natural Polymer-Based Medical Materials, Zhongnan Hospital of Wuhan University, Wuhan, 430071, Hubei, China. ; Zhongzh
期刊:Hypothermic machine perfusion reduces donation after circulatory death liver ischemia–reperfusion injury through the SERPINA3-mediated PI3Kδ/Akt pathway
DOI:10.1007/s13577-023-01012-3
影响因子 :4.3
引用产品: BRL 3A 细胞
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Transcriptomic analysis of hepatocytes reveals the association between ubiquitin-specific peptidase 1 and yes-associated protein 1 during liver regeneration (2023-07-21)
作者:Yalei Zhao:1.Department of Infectious Diseases, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; 2.State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. ; Fen Zhang:1.State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. ; Xiaoli Zhang:1.Department of Infectious Diseases, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. ; Zuhong Li:1.State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Cente
期刊:Transcriptomic analysis of hepatocytes reveals the association between ubiquitin-specific peptidase 1 and yes-associated protein 1 during liver regeneration
DOI:10.1016/j.reth.2023.07.004
影响因子 :4.3
引用产品: BRL 3A 细胞
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Enhanced US/CT/MR imaging of integrin αvβ3 for liver fibrosis staging in rat (2022-10-03)
作者:Xueyao Tang:1.Department of Ultrasound, The Affiliated Hospital of Southwest Medical University, Luzhou, China. ; 2.Department of Ultrasound, The Third People's Hospital of Chengdu, Clinical College of Southwest Jiao Tong University, The Second Affiliated Chengdu Hospital of Chongqing Medical University, Chengdu, China. ; Xuan Li:1.Department of Ultrasound, The Affiliated Hospital of Southwest Medical University, Luzhou, China. ; 2.Department of Ultrasound, Sichuan Provincial People's Hospital, Chengdu, China. ; Mingxing Li:1.Department of Ultrasound, The Affiliated Hospital of Southwest Medical University, Luzhou, China. ; Xiaoling Zhong:1.Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, China. ; Wenguang Fu:1.Academician (Expert) Workstation of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, China. ; 2.Department of Hepatobiliary Surgery, The Affiliated Hospital of Southwest Medical University, Luz
期刊:Enhanced US/CT/MR imaging of integrin αvβ3 for liver fibrosis staging in rat
影响因子 :5.5
引用产品: BRL 3A 细胞
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Ginseng polysaccharide attenuates red blood cells oxidative stress injury by regulating red blood cells glycolysis and liver gluconeogenesis (2022-09-16)
作者:Siming Wang:1.Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China. Electronic address: lwsm126030@126.com. ; Yuchu Zhao:1.Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China. Electronic address: 739912973@qq.com. ; Junjie Yang:1.Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China. Electronic address: abc_592940227@qq.com. ; Shichao Liu:1.Academic Affairs Office, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China. Electronic address: aralekyra@163.com. ; Weifeng Ni:1.Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China. Electronic address: 1277393729@qq.c
期刊:Ginseng polysaccharide attenuates red blood cells oxidative stress injury by regulating red blood cells glycolysis and liver gluconeogenesis
影响因子 :5.2
引用产品: BRL 3A 细胞
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Zanthoxylum armatum DC. extract induces liver injury via autophagy suppression and oxidative damage by activation of mTOR/ULK1 pathway (2022-08-14)
作者:Yan Huang:1.School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Jialuo Jiang:1.Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Wenlin Wang:1.Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Jiafu Guo:1.School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Nannan Yang:1.School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Jian Zhang:1.School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Qiuyan Liu:1.School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Yan Chen:1.School of Public Health, Chengdu Univ
期刊:Zanthoxylum armatum DC. extract induces liver injury via autophagy suppression and oxidative damage by activation of mTOR/ULK1 pathway
DOI:10.1016/j.toxicon.2022.08.008
影响因子 :3.0
引用产品: BRL 3A 细胞 , BRL细胞专用培养基
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Tissue-Specific Hydrogels Ameliorate Hepatic Ischemia/Reperfusion Injury in Rats by Regulating Macrophage Polarization via TLR4/NF-κB Signaling (2003-01-20)
作者:Shuai Li:1.Laboratory of Basic Medicine, The General Hospital of Western Theater Command, Chengdu 610083, China. ; 2.Department of General Surgery & Pancreatic Injury and Repair Key Laboratory of Sichuan Province, The General Hospital of Western Theater Command, Chengdu 610083, China. ; 3.College of Medicine, Southwest Jiaotong University, Chengdu 610083, China. ; Chengxiao Liang:1.Department of General Surgery & Pancreatic Injury and Repair Key Laboratory of Sichuan Province, The General Hospital of Western Theater Command, Chengdu 610083, China. ; Wen Jiang:1.Laboratory of Basic Medicine, The General Hospital of Western Theater Command, Chengdu 610083, China. ; 2.Department of General Surgery & Pancreatic Injury and Repair Key Laboratory of Sichuan Province, The General Hospital of Western Theater Command, Chengdu 610083, China. ; 3.College of Medicine, Southwest Jiaotong University, Chengdu 610083, China. ; Jie Deng:1.College of Medicine, Southwest Jiaotong University, Chengdu 61
期刊:Tissue-Specific Hydrogels Ameliorate Hepatic Ischemia/Reperfusion Injury in Rats by Regulating Macrophage Polarization via TLR4/NF-κB Signaling
DOI:10.1021/acsbiomaterials.0c01610
影响因子 :5.8
引用产品: BRL 3A 细胞
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Activation of ATM/Chk2 by Zanthoxylum armatum DC extract induces DNA damage and G1/S phase arrest in BRL 3A cells. (2011-01-20)
作者:Jialuo Jiang:1.School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China; Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Yan Huang:1.Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China; School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Wenlin Wang:1.School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China; Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. ; Chen Sun:1.School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China; Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of T
期刊:Activation of ATM/Chk2 by Zanthoxylum armatum DC extract induces DNA damage and G1/S phase arrest in BRL 3A cells.
影响因子 :5.4
引用产品: BRL 3A 细胞
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Hydrolyzed camel whey protein alleviated heat stress-induced hepatocyte damage by activated Nrf2/HO-1 signaling pathway and inhibited NF-κB/NLRP3 axis (2001-01-20)
作者:Donghua Du:1.Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, 010018, China. ; 2.Department of Veterinary Medicine, College of Animal Science and Technology, Hebei North University, Zhangjiakou, 075131, Hebei, China. ; Wenting Lv:1.Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, 010018, China. ; 2.Department of Veterinary Medicine, College of Animal Science and Technology, Hebei North University, Zhangjiakou, 075131, Hebei, China. ; Rina Su:1.Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture, College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, 010018, China. ; Chunwei Yu:1.Key Laboratory of Clinical Diagnosis and Treatment Technolo
期刊:Hydrolyzed camel whey protein alleviated heat stress-induced hepatocyte damage by activated Nrf2/HO-1 signaling pathway and inhibited NF-κB/NLRP3 axis
DOI:10.1007/s12192-020-01184-z
影响因子 :3.8
引用产品: BRL 3A 细胞
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Comparison of bone marrow‑vs. adipose tissue‑derived mesenchymal stem cells for attenuating liver fibrosis (2010-07-20)
作者:Tianpao Hao:1.Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China. ; Jingfeng Chen:1.Department of Anorectal Surgery, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 325000, P.R. China. ; Shaoce Zhi:1.Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China. ; Qiyu Zhang:1.Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China. ; Gang Chen:1.Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China. ; Fuxiang Yu:1.Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China. ;
期刊:Comparison of bone marrow‑vs. adipose tissue‑derived mesenchymal stem cells for attenuating liver fibrosis
影响因子 :2.7
引用产品: BRL 3A 细胞
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Ultrasound molecular imaging with cRGD-PLGA-PFOB nanoparticles for liver fibrosis staging in a rat model (2009-07-20)
作者:Jiqing Xuan:1.Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University & Chongqing Key Laboratory of Ultrasound Molecular Imaging, Chongqing 400010, China. ; 2.Department of Ultrasound, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China. ; Yuli Chen:1.Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University & Chongqing Key Laboratory of Ultrasound Molecular Imaging, Chongqing 400010, China. ; Leilei Zhu:1.Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University & Chongqing Key Laboratory of Ultrasound Molecular Imaging, Chongqing 400010, China. ; Yuan Guo:1.Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University & Chongqing Key Laboratory of Ultrasound Molecular Imaging, Chongqing 400010, China. ; Liming Deng:1.Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University & Chongqing Key Laboratory of
期刊:Ultrasound molecular imaging with cRGD-PLGA-PFOB nanoparticles for liver fibrosis staging in a rat model
影响因子 :0.0
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