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产品概述
| 名称 | C6 (大鼠胶质瘤细胞) (种属鉴定正确) |
| 别称 | C-6; C 6; RGC-6; RGC6; RGc6 |
| 种属 | 大鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 成纤维细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | 胶质细胞株C6是由Benda等用N-亚硝基甲脲诱导的大鼠胶质瘤克隆，并经过一系列的体外培养和动物传代交替后建成的。C6细胞表达S-100；产生生长激素；糖皮质激素作用下可以产生磷酸甘油脱氢酶。当C6细胞从低密度生长到满瓶时，S-100产量增加10倍。 |
| 组织来源 | 胶质瘤，脑，胶质细胞 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胶质瘤细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~25-30 hours |
| 受体表达情况 | glucocorticoid receptor |
| 基因表达情况 | S-100 protein; produce glyceryl phosphate dehydrogenase in response to glucocorticoids; somatotrophin |
| 保藏机构 | ATCC; CCL-107 BCRC; 60046 BCRJ; 0057 DSMZ; ACC-550 ECACC; 92090409 |
种属鉴定
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种属鉴定图
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参考文献
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Elucidating the mechanisms underlying astrocyte-microglia crosstalk in hippocampal neuroinflammation induced by acute diquat exposure (2024-02-02)
作者：Changcun Qi:1.Department of Occupational Health and Environmental Health, School of Public Health, Hebei Medical University, Shijiazhuang, 050000, Hebei, China. ; 2.Hebei Key Laboratory of Environment and Human Health, Shijiazhuang, 050000, Hebei, China. ; Yuandong Yan:1.Department of Occupational Health and Environmental Health, School of Public Health, Hebei Medical University, Shijiazhuang, 050000, Hebei, China. ; 2.Hebei Key Laboratory of Environment and Human Health, Shijiazhuang, 050000, Hebei, China. ; Qi Cao:1.Department of Occupational Health and Environmental Health, School of Public Health, Hebei Medical University, Shijiazhuang, 050000, Hebei, China. ; 2.Hebei Key Laboratory of Environment and Human Health, Shijiazhuang, 050000, Hebei, China. ; Lingyun Zou:1.Department of Occupational Health and Environmental Health, School of Public Health, Hebei Medical University, Shijiazhuang, 050000, Hebei, China. ; 2.Hebei Key Laboratory of Environment and Human Health, Shijiazhuan
期刊：Elucidating the mechanisms underlying astrocyte-microglia crosstalk in hippocampal neuroinflammation induced by acute diquat exposure
DOI：10.1007/s11356-024-31905-1
影响因子 ：5.8
引用产品： C6 细胞
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Effect of doramectin on programmed cell death pathway in glioma cells (2023-04-21)
作者：Songlin Du:1.Department of Biochemistry and Molecular Biology, College of Life Sciences, Northeast Agricultural University, Harbin, 150030, China. ; Hongsheng Liang:1.Department of Neurosurgery, First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China. ; Lu Zhou:1.Department of Biochemistry and Molecular Biology, College of Life Sciences, Northeast Agricultural University, Harbin, 150030, China. ; Chen Chen:1.Department of Biochemistry and Molecular Biology, College of Life Sciences, Northeast Agricultural University, Harbin, 150030, China. ; Ruimeng Sun:1.Department of Biochemistry and Molecular Biology, College of Life Sciences, Northeast Agricultural University, Harbin, 150030, China. ; Jie Zhang:1.Department of Neurosurgery, First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China. ; Xiangyi Meng:1.Department of Neurosurgery, First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China. ; Aili Gao:1.Department of Bio
期刊：Effect of doramectin on programmed cell death pathway in glioma cells
DOI：10.1007/s12094-023-03147-z
影响因子 ：3.4
引用产品： C6 细胞 , STR鉴定
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Reversible Deformation of Artificial Cell Colony Triggered by Actin Polymerization for Muscle Behavior Mimicry (2007-02-20)
作者：Chao Li:1.State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, 150001, China. ; Xiangxiang Zhang:1.State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, 150001, China. ; Boyu Yang:1.State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, 150001, China. ; Feng Wei:1.State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, 150001, China. ; Yongshuo Ren:1.State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, 150001
期刊：Reversible Deformation of Artificial Cell Colony Triggered by Actin Polymerization for Muscle Behavior Mimicry
影响因子 ：29.4
引用产品： C6 细胞
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Neuropeptide Y in the amygdala contributes to neuropathic pain-like behaviors in rats via the neuropeptide Y receptor type 2/mitogen-activated protein kinase axis (2003-02-20)
作者：Wenhui Yan:1.Department of Laboratory Medicine Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, P.R. China. ; 2.Department of Laboratory Medicine, Tinghu People's Hospital, Yancheng, P.R. China. ; Wuchao Liu:1.Department of Neurorehabilitation, Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, P.R. China. ; Junlu Wu:1.Department of Laboratory Medicine, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, P.R. China. ; Lipei Wu:1.Department of Laboratory Medicine, Dongtai People's Hospital & Dongtai Hospital of Nantong University, Yancheng, P.R. China. ; Shihai Xuan:1.Department of Laboratory Medicine, Dongtai People's Hospital & Dongtai Hospital of Nantong University, Yancheng, P.R. China. ; Weiwei Wang:1.Department of Pathology, Tinghu People's Hospital, Yancheng, P.R. China. ; Anquan Shang:1.Department of Laborat
期刊：Neuropeptide Y in the amygdala contributes to neuropathic pain-like behaviors in rats via the neuropeptide Y receptor type 2/mitogen-activated protein kinase axis
DOI：10.1080/21655979.2022.2051783
影响因子 ：4.9
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Transferrin/Folate Dual-Targeting Pluronic F127/Poly(lactic acid) Polymersomes for Effective Anticancer Drug Delivery (2002-02-20)
作者：Qing Xiao Wang:1.School of Life Science, Jiangxi Science and Technology Normal University, Nanchang, PR China. ; Xiang Chen:1.School of Life Science, Jiangxi Science and Technology Normal University, Nanchang, PR China. ; Zi Ling Li:1.School of Life Science, Jiangxi Science and Technology Normal University, Nanchang, PR China. ; Yan Chun Gong:1.School of Life Science, Jiangxi Science and Technology Normal University, Nanchang, PR China. ; Xiang Yuan Xiong:1.School of Life Science, Jiangxi Science and Technology Normal University, Nanchang, PR China. ;
期刊：Transferrin/Folate Dual-Targeting Pluronic F127/Poly(lactic acid) Polymersomes for Effective Anticancer Drug Delivery
DOI：10.1080/09205063.2022.2044434
影响因子 ：3.6
引用产品： C6 细胞
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Novel piperazine based benzamide derivatives as potential anti-glioblastoma agents inhibiting cell proliferation and cell cycle progression (2010-01-20)
作者：Yingmei Lu:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Yiyue Feng:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Zhao Li:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Junfang Li:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Honghua Zhang:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Xiaoling Hu:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Weifan Jiang:1.School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China. ; Tao Shi:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Zhen Wang:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China; School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China; State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou Univer
期刊：Novel piperazine based benzamide derivatives as potential anti-glioblastoma agents inhibiting cell proliferation and cell cycle progression
DOI：10.1016/j.ejmech.2021.113908
影响因子 ：7.1
引用产品： U-87 MG 细胞 , U251 细胞 , C6 细胞
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N-2-(phenylamino) benzamide derivatives as novel anti-glioblastoma agents: Synthesis and biological evaluation (2009-01-20)
作者：Junfang Li:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Xiaoling Hu:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Tian Luo:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Yingmei Lu:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Yiyue Feng:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Honghua Zhang:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Dan Liu:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Xiaohong Fan:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Yuqing Wang:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Liming Jiang:1.School of Pharmacy, Lanzhou University, Lanzhou, 730000, China. ; Yuying Wang:1.State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, China. ; Xiangyong Hao:1.Department of General
期刊：N-2-(phenylamino) benzamide derivatives as novel anti-glioblastoma agents: Synthesis and biological evaluation
DOI：10.1016/j.ejmech.2021.113817
影响因子 ：6.7
引用产品： U-87 MG 细胞 , U251 细胞 , C6 细胞 , MEM非必需氨基酸溶液 (NEAA)，100×
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