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产品概述
| 名称 | bEnd.3 [BEND3] (小鼠脑微血管内皮细胞) (STR鉴定正确) |
| 别称 | bEND.3; b.End3; Bend.3; bEnd3; brain-derived Endothelial cells.3 |
| 种属 | 小鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 1.该细胞在低密度下形态不规则，细胞数量少，铺展面积大，高密度后形态会趋于一致，胞体密集；2.细胞增殖偏慢，初次传代建议1:2，细胞稳定后建议传代比例也不超过1:4；3.注意观察培养基颜色，颜色偏紫会导致细胞漂浮增加；4.消化时间会随着细胞生长时间和细胞密度而有所不同，需要结合消化时细胞状态来判断，消化到细胞可以滑落方可终止。 |
| 背景描述 | The cells were transformed by infection with the NTKmT retrovirus vector that expresses polyomavirus middle T antigen |
| 年龄（性别） | 6周龄 |
| 组织来源 | 大脑皮层 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-1 |
| 抗原表达情况 | ICAM-1 +; VCAM-1 +; MAdCAM-1 + |
| 基因表达情况 | von Willebrand factor,ICAM-1 +; VCAM-1 +; MAdCAM-1 +,The endothelial nature of these cells was confirmed by the observed expression of von Willebrand factor and uptake of fluorescently labeled low density lipoprotein (LDL).,The expression of Peyer's Patch high endothelial receptor for lymphocytes, the mucosal vascular addressin (MAdCAM-1) and E-selectin can be induced on bEnd |
| 保藏机构 | ATCC; CRL-2299 BCRC; 60515 ECACC; 96091929 |
STR鉴定
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STR位点信息
18-3 18 6-7 11,12 5-5 14 X-1 26 1-2 13 7-1 29 8-1 16 1-1 10 19-2 13 15-3 19.3,20.3 12-1 17 6-4 17 4-2 18.3 3-2 14 2-1 9 13-1 16.2
11-2 14 17-2 12 -
STR鉴定图
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参考文献
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Engineered Extracellular Vesicles Modified by Angiopep-2 Peptide Promote Targeted Repair of Spinal Cord Injury and Brain Inflammation (2025-01-24)
期刊：ACS Nano
影响因子 ：15.8
引用产品： bEnd.3 [BEND3] 细胞 , C8-D1A 细胞
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Traditional Chinese Medicine Borneol-Based Polymeric Micelles Intracerebral Drug Delivery System for Precisely Pathogenesis-Adaptive Treatment of Ischemic Stroke (2025-01-13)
期刊：Advanced Science
影响因子 ：14.3
引用产品： SH-SY5Y [SHSY-5Y] 细胞 , bEnd.3 [BEND3] 细胞 , BV2 细胞
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Heat acclimation mediates cellular protection via HSP70 stabilization of HIF-1α protein in extreme environments (2025-01-01)
期刊：International Journal of Biological Sciences
影响因子 ：8.2
引用产品： bEnd.3 [BEND3] 细胞
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A novel supramolecular nanodrugs for improving the cognitive function of schizophrenia by protecting active lactone of arecoline (2025-01-17)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2025.117845
影响因子 ：6.9
引用产品： PC-12 (Low differentiation) 细胞 , bEnd.3 [BEND3] 细胞 , Neuro-2a [N2a; Neuro-2a] 细胞
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GYY4137 ameliorates blood brain barrier damage by inhibiting autophagy mediated occludin degradation in cardiac arrest and resuscitation (2025-01-06)
期刊：Scientific Reports
DOI：10.1038/s41598-024-84948-2
影响因子 ：3.8
引用产品： bEnd.3 [BEND3] 细胞
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A Peptide-Drug Conjugate-Based Nanoplatform for Immunometabolic Activation and In Situ Nerve Regeneration in Advanced-Stage Alzheimer's Disease (2024-09-26)
期刊：ADVANCED MATERIALS
影响因子 ：27.4
引用产品： BV2 细胞 , bEnd.3 [BEND3] 细胞
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Apoptotic Bodies Derived from Fibroblast-Like Cells in Subcutaneous Connective Tissue Inhibit Ferroptosis in Ischaemic Flaps via the miR-339-5p/KEAP1/Nrf2 Axis (2024-04-19)
期刊：Advanced Science
影响因子 ：15.1
引用产品： L Wnt-3A 细胞 , bEnd.3 [BEND3] 细胞 , DMEM高糖 培养基 , RAW 264.7 细胞 , 磷酸盐缓冲液（PBS） 1×
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ROS-mediated lysosomal membrane permeabilization and autophagy inhibition regulate bleomycin-induced cellular senescence (2024-05-18)
期刊：Autophagy
DOI：10.1080/15548627.2024.2353548
影响因子 ：14.6
引用产品： HT22 细胞 , bEnd.3 [BEND3] 细胞
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Near-Infrared II ratiometric photoacoustic imaging of copper ions in Alzheimer’s disease mice by using biomineralized nanoprobes (2024-12-26)
期刊：CHEMICAL ENGINEERING JOURNAL
影响因子 ：13.3
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Kdm6a-CNN1 axis orchestrates epigenetic control of trauma-induced spinal cord microvascular endothelial cell senescence to balance neuroinflammation for improved neurological repair (2024-03-25)
期刊：Bone Research
DOI：10.1038/s41413-024-00323-x
影响因子 ：12.7
引用产品： bEnd.3 [BEND3] 细胞
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MCT1-mediated endothelial cell lactate shuttle as a target for promoting axon regeneration after spinal cord injury (2024-09-03)
期刊：Theranostics
影响因子 ：12.4
引用产品： bEnd.3 [BEND3] 细胞 , 青霉素-链霉素溶液（双抗），100× , CATH.a细胞专用培养基
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Intranasal delivery of small extracellular vesicles from specific subpopulation of mesenchymal stem cells mitigates traumatic spinal cord injury (2024-04-03)
期刊：JOURNAL OF CONTROLLED RELEASE
DOI：10.1016/j.jconrel.2024.03.037
影响因子 ：10.8
引用产品： bEnd.3 [BEND3] 细胞
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Biomimetic astrocyte cell membrane-fused nanovesicles for protecting neurovascular units in hypoxic ischemic encephalopathy (2024-12-19)
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-024-03053-8
影响因子 ：10.6
引用产品： C8-D1A 细胞 , bEnd.3 [BEND3] 细胞
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Neutrophil membrane-derived nanoparticles protect traumatic brain injury via inhibiting calcium overload and scavenging ROS (2024-08-12)
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-024-02753-5
影响因子 ：10.6
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Enhancing Neuroprotection in Mouse Model of Parkinson’s Disease through Protein Nanosystem Conjugation with ApoE Peptide for miR-124 Delivery (2024-02-12)
期刊：ACS Applied Materials & Interfaces
影响因子 ：9.5
引用产品： bEnd.3 [BEND3] 细胞
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A biomimetic targeted nanosystem delivering synergistic inhibitors for glioblastoma immune microenvironment reprogramming and treatment (2024-09-01)
期刊：Materials Today Bio
DOI：10.1016/j.mtbio.2024.101222
影响因子 ：8.7
引用产品： bEnd.3 [BEND3] 细胞 , U-87 MG 细胞
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The Syvn1 inhibits neuronal cell ferroptosis by activating Stat3/Gpx4 axis in rat with spinal cord injury (2024-05-27)
期刊：CELL PROLIFERATION
影响因子 ：8.5
引用产品： 293T [HEK-293T] 细胞 , BV2 (DMEM) 细胞 , bEnd.3 [BEND3] 细胞
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Hypoxia-Responsive Biomimetic Nanobubbles for Oxygen Delivery Promote Synergistic Ischemic Stroke Protection (2024-09-24)
期刊：ACS Applied Materials & Interfaces
影响因子 ：8.3
引用产品： bEnd.3 [BEND3] 细胞
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Protein corona potentiates recovery of nanoparticle-induced disrupted tight junctions in endothelial cells (2024-11-08)
期刊：Nanoscale Horizons
影响因子 ：8.0
引用产品： bEnd.3 [BEND3] 细胞
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The Dual Angiogenesis Effects via Nrf2/HO-1 Signaling Pathway of Melatonin Nanocomposite Scaffold on Promoting Diabetic Bone Defect Repair (2024-03-15)
期刊：International Journal of Nanomedicine
影响因子 ：8.0
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Buyang Huanwu Decoction Promotes Angiogenesis after Cerebral Ischemia through Modulating Caveolin-1-Mediated Exosome MALAT1/YAP1/HIF-1α axis (2024-04-08)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155609
影响因子 ：7.9
引用产品： bEnd.3 [BEND3] 细胞
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Thiols-rich peptide from water buffalo horn keratin alleviates oxidative stress and inflammation through co-regulating Nrf2/Hmox-1 and NF-κB signaling pathway (2024-07-29)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.07.023
影响因子 ：7.1
引用产品： bEnd.3 [BEND3] 细胞 , RAW 264.7 细胞
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Ginsenoside Rg2 alleviates astrocyte inflammation and ameliorates the permeability of the Alzheimer's disease related blood-brain barrier (2024-09-16)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.156063
影响因子 ：6.7
引用产品： bEnd.3 [BEND3] 细胞
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Key Lipoprotein Receptor Targeted Echinacoside-Liposomes Effective Against Parkinson’s Disease in Mice Model (2024-08-20)
期刊：International Journal of Nanomedicine
影响因子 ：6.6
引用产品： bEnd.3 [BEND3] 细胞
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Neuroinflammation-targeted magnetic resonance imaging nanoprobes for the early diagnosis of Alzheimer's disease (2024-12-05)
期刊：Journal of Materials Chemistry B
影响因子 ：6.1
引用产品： BV2 细胞 , bEnd.3 [BEND3] 细胞
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Cerium Oxide-Modified Pd Nanosheets Encapsulated by Red Blood Cell Membranes with High-Efficiency RONS Scavenging for Depression Treatment (2024-10-14)
期刊：Nanoscale
影响因子 ：5.8
引用产品： PC-12 (High differentiation) 细胞 , NCTC clone 929 [L cell, L-929] 细胞 , bEnd.3 [BEND3] 细胞
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Exosome-mediated delivery platform of biomacromolecules into the brain: Cetuximab in combination with doxorubicin for glioblastoma therapy (2024-05-28)
期刊：INTERNATIONAL JOURNAL OF PHARMACEUTICS
DOI：10.1016/j.ijpharm.2024.124262
影响因子 ：5.8
引用产品： bEnd.3 [BEND3] 细胞 , C6 细胞
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Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury (2024-04-09)
期刊：Neuroscience Bulletin
DOI：10.1007/s12264-024-01199-x
影响因子 ：5.6
引用产品： bEnd.3 [BEND3] 细胞
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Minimally invasive vagus nerve stimulation modulates mast cell degranulation via the microbiota-gut-brain axis to ameliorate blood-brain barrier and intestinal barrier damage following ischemic stroke (2024-04-10)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112030
影响因子 ：5.6
引用产品： P815 细胞 , bEnd.3 [BEND3] 细胞
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Erjingpill bionic cerebrospinal fluid alleviates LPS-induced inflammatory response in BV2 cells by inhibiting glycolysis via mTOR (2024-05-31)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
引用产品： bEnd.3 [BEND3] 细胞
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Canagliflozin protects against hyperglycemia-induced cerebrovascular injury by preventing blood-brain barrier (BBB) disruption via AMPK/Sp1/adenosine A2A receptor (2024-02-09)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2024.176381
影响因子 ：5.0
引用产品： bEnd.3 [BEND3] 细胞
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Preparation and Pharmacokinetics of Brain-Targeted Nanoliposome Loaded with Rutin (2024-10-23)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：4.9
引用产品： bEnd.3 [BEND3] 细胞
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A novel study of brain microvascular endothelial cells induced by astrocyte conditioned medium for constructing blood brain barrier model in vitro: A promising tool for meningitis of teleost (2024-01-23)
期刊：FISH & SHELLFISH IMMUNOLOGY
影响因子 ：4.7
引用产品： bEnd.3 [BEND3] 细胞
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Trifluoperazine regulates blood-brain barrier permeability via the MLCK/p-MLC pathway to promote ischemic stroke recovery (2024-02-13)
期刊：iScience
DOI：10.1016/j.isci.2024.109156
影响因子 ：4.6
引用产品： bEnd.3 [BEND3] 细胞
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The Tumor-Derived Exosomes Enhanced Bevacizumab across the Blood–Brain Barrier for Antiangiogenesis Therapy against Glioblastoma (2024-12-30)
期刊：MOLECULAR PHARMACEUTICS
DOI：10.1021/acs.molpharmaceut.4c01227
影响因子 ：4.5
引用产品： bEnd.3 [BEND3] 细胞
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Microfluidic Preparation and Evaluation of Multivesicular Liposomes Containing Gastrodin for Oral Delivery across the Blood–Brain Barrier (2024-10-05)
期刊：MOLECULAR PHARMACEUTICS
DOI：10.1021/acs.molpharmaceut.4c00582
影响因子 ：4.5
引用产品： Hank's平衡盐溶液（HBSS），含钙、镁，不含酚红 , C8-D1A 细胞 , DMEM高糖 培养基 , bEnd.3 [BEND3] 细胞 , 特级胎牛血清 , 磷酸盐缓冲液（PBS） 1×
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GSK3β Substrate-competitive Inhibitors Regulate the gut Homeostasis and Barrier Function to Inhibit Neuroinflammation in Scopolamine-induced Alzheimer’s Disease Model Mice (2024-08-24)
期刊：INFLAMMATION
DOI：10.1007/s10753-024-02133-z
影响因子 ：4.5
引用产品： bEnd.3 [BEND3] 细胞
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Butylated hydroxyanisole induces vascular endothelial injury via TFEB-mediated degradation of GPX4 and FTH1 (2024-04-22)
期刊：FOOD AND CHEMICAL TOXICOLOGY
影响因子 ：4.3
引用产品： HUV-EC-C [HUVEC]细胞专用培养基 , bEnd.3 [BEND3] 细胞 , 人脐静脉内皮细胞 , DMEM高糖 培养基 , 青霉素-链霉素溶液（双抗），100×
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Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption (2024-02-22)
期刊：NEUROCHEMISTRY INTERNATIONAL
DOI：10.1016/j.neuint.2024.105702
影响因子 ：4.2
引用产品： bEnd.3 [BEND3] 细胞
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Neferine inhibits BMECs pyroptosis and maintains blood–brain barrier integrity in ischemic stroke by triggering a cascade reaction of PGC-1α (2024-06-23)
期刊：Scientific Reports
DOI：10.1038/s41598-024-64815-w
影响因子 ：3.8
引用产品： DMEM无糖 培养基 , bEnd.3 [BEND3] 细胞 , bEnd.3 [BEND3]细胞专用培养基
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Propofol Protects the Blood-Brain Barrier After Traumatic Brain Injury by Stabilizing the Extracellular Matrix via Prrx1: From Neuroglioma to Neurotrauma (2024-07-01)
期刊：NEUROCHEMICAL RESEARCH
DOI：10.1007/s11064-024-04202-z
影响因子 ：3.7
引用产品： C8-D1A 细胞 , bEnd.3 [BEND3] 细胞
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Long noncoding RNA KCNQ1OT1 aggravates cerebral infarction by regulating PTBT1/SIRT1 via miR-16-5p (2024-02-07)
期刊：JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
影响因子 ：3.2
引用产品： bEnd.3 [BEND3] 细胞
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Preparation and brain targeting effects study of recombinant human ferritin nanoparticles (2024-04-15)
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2024.149939
影响因子 ：3.1
引用产品： bEnd.3 [BEND3] 细胞
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M1-type microglia-derived exosomes contribute to blood–brain barrier damage (2024-04-06)
期刊：BRAIN RESEARCH
DOI：10.1016/j.brainres.2024.148919
影响因子 ：2.9
引用产品： bEnd.3 [BEND3] 细胞 , BV2 (DMEM) 细胞
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Heat acclimation alleviates the heat stress-induced impairment of vascular endothelial cells (2024-08-09)
期刊：TISSUE & CELL
DOI：10.1016/j.tice.2024.102520
影响因子 ：2.7
引用产品： bEnd.3 [BEND3] 细胞 , 人脐静脉内皮细胞 , 人主动脉内皮细胞
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Lentivirus-Mediated Missense Mutation in HtrA1 Leads to Activation of the TGF-β/Smads Pathway and Increased Apoptosis of Mouse Brain Microvascular Endothelial Cells via the Oxidative Stress Pathway (2024-10-31)
期刊：Journal of Integrative Neuroscience
影响因子 ：2.5
引用产品： bEnd.3 [BEND3] 细胞
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Targeting TXNIP for neuroprotection: A novel approach to reducing inflammation and promoting recovery in ischemic stroke (2024-12-13)
期刊：Biomolecules and Biomedicine
影响因子 ：0.0
引用产品： bEnd.3 [BEND3] 细胞
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Catechin-functionalized Cationic Lipopolymer Based Multicomponent Nanomicelles for Lung-Targeting Delivery (2023-08-09)
期刊：ADVANCED MATERIALS
影响因子 ：29.4
引用产品： bEnd.3 [BEND3] 细胞 , A549 [A-549] 细胞
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Targeted Delivery of RGD-CD146+CD271+ Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Promotes Blood–Spinal Cord Barrier Repair after Spinal Cord Injury (2023-09-11)
期刊：ACS Nano
影响因子 ：17.1
引用产品： bEnd.3 [BEND3] 细胞
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C3N nanodots inhibits Aβ peptides aggregation pathogenic path in Alzheimer’s disease (2023-09-15)
期刊：Nature Communications
DOI：10.1038/s41467-023-41489-y
影响因子 ：16.6
引用产品： bEnd.3 [BEND3] 细胞 , BV2 细胞
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Neuroinflammation catching nanobubbles for microglia-neuron unit modulation against epilepsy (2023-08-30)
期刊：BIOMATERIALS
DOI：10.1016/j.biomaterials.2023.122302
影响因子 ：14.0
引用产品： bEnd.3 [BEND3] 细胞 , BV2 细胞 , HT22 细胞
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VEGF-A in serum protects against memory impairment in APP/PS1 transgenic mice by blocking neutrophil infiltration (2023-06-06)
期刊：MOLECULAR PSYCHIATRY
DOI：10.1038/s41380-023-02097-w
影响因子 ：11.0
引用产品： bEnd.3 [BEND3] 细胞
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Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p (2023-09-29)
期刊：Cell Death & Disease
DOI：10.1038/s41419-023-06173-5
影响因子 ：9.0
引用产品： BV2 细胞 , bEnd.3 [BEND3] 细胞
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Protection of a novel velvet antler polypeptide PNP1 against cerebral ischemia-reperfusion injury (2023-07-13)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2023.125815
影响因子 ：8.2
引用产品： bEnd.3 [BEND3] 细胞 , BV2 细胞
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A Dual Receptor Targeting- and BBB Penetrating- Peptide Functionalized Polyethyleneimine Nanocomplex for Secretory Endostatin Gene Delivery to Malignant Glioma (2023-01-05)
期刊：International Journal of Nanomedicine
影响因子 ：8.0
引用产品： bEnd.3 [BEND3] 细胞
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Active fraction of Polyrhachis vicina (Roger) alleviated cerebral ischemia/reperfusion injury by targeting SIRT3-mediated mitophagy and angiogenesis (2023-09-18)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2023.155104
影响因子 ：7.9
引用产品： bEnd.3 [BEND3] 细胞
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Elabela-APJ axis mediates angiogenesis via YAP/TAZ pathway in cerebral ischemia/reperfusion injury (2023-02-21)
期刊：Translational Research
DOI：10.1016/j.trsl.2023.02.002
影响因子 ：7.8
引用产品： bEnd.3 [BEND3] 细胞
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A Novel Blood–Brain Barrier-Penetrating and Vascular-Targeting Chimeric Peptide Inhibits Glioma Angiogenesis (2023-05-15)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.6
引用产品： bEnd.3 [BEND3] 细胞
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Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke (2023-11-18)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.111183
影响因子 ：5.6
引用产品： bEnd.3 [BEND3] 细胞
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MCC950 alleviates seizure severity and angiogenesis by inhibiting NLRP3/ IL-1β signaling pathway-mediated pyroptosis in mouse model of epilepsy (2023-11-30)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.111236
影响因子 ：5.6
引用产品： BV2 细胞 , bEnd.3 [BEND3] 细胞
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Mechanism of neocryptotanshinone in protecting against cerebral ischemic injury: By suppressing M1 polarization of microglial cells and promoting cerebral angiogenesis (2023-02-09)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.109815
影响因子 ：5.6
引用产品： BV2 细胞 , bEnd.3 [BEND3] 细胞
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USP14 inhibition promotes recovery by protecting BBB integrity and attenuating neuroinflammation in MCAO mice (2023-06-02)
期刊：CNS Neuroscience & Therapeutics
影响因子 ：5.5
引用产品： bEnd.3 [BEND3] 细胞
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Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury (2023-08-29)
期刊：CNS Neuroscience & Therapeutics
影响因子 ：5.5
引用产品： bEnd.3 [BEND3] 细胞 , RAW 264.7 细胞
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Advanced Glycation End-Products (AGEs) Promote Endothelial Cell Pyroptosis Under Cerebral Ischemia and Hypoxia via HIF-1α-RAGE-NLRP3 (2023-01-18)
期刊：MOLECULAR NEUROBIOLOGY
DOI：10.1007/s12035-023-03228-8
影响因子 ：5.1
引用产品： 小鼠脑微血管内皮细胞 , bEnd.3 [BEND3] 细胞
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Interfering TRIB3 protects the blood brain barrier through PI3K/Akt pathway to alleviate cerebral ischemia-reperfusion injury in diabetes mellitus mice (2023-11-18)
期刊：CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 ：5.1
引用产品： bEnd.3 [BEND3] 细胞
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Nuclear Factor Erythroid 2-Related Factor 2 is Essential for Low-Normobaric Oxygen Treatment-Mediated Blood-Brain Barrier Protection Following Ischemic Stroke (2023-11-11)
期刊：MOLECULAR NEUROBIOLOGY
DOI：10.1007/s12035-023-03767-0
影响因子 ：5.1
引用产品： bEnd.3 [BEND3] 细胞
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Conditional Knockout of IL-1R1 in Endothelial Cells Attenuates Seizures and Neurodegeneration via Inhibiting Neuroinflammation Mediated by Nrf2/HO-1/NLRP3 Signaling in Status Epilepticus Model (2023-12-12)
期刊：MOLECULAR NEUROBIOLOGY
DOI：10.1007/s12035-023-03842-6
影响因子 ：5.1
引用产品： bEnd.3 [BEND3] 细胞 , BV2 细胞
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GPR124 induces NLRP3 inflammasome-mediated pyroptosis in endothelial cells during ischemic injury (2023-12-01)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2023.176228
影响因子 ：5.0
引用产品： bEnd.3 [BEND3] 细胞
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Overexpression of ACE2 ameliorates Aβ-induced blood–brain barrier damage and angiogenesis by inhibiting NF-κB/VEGF/VEGFR2 pathway (2023-05-14)
期刊：Animal Models and Experimental Medicine
影响因子 ：3.7
引用产品： bEnd.3 [BEND3] 细胞
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Vascular endothelial cell-derived exosomal miR-1246 facilitates posterior capsule opacification development by targeting GSK-3β in diabetes mellitus (2023-04-10)
期刊：EXPERIMENTAL EYE RESEARCH
DOI：10.1016/j.exer.2023.109463
影响因子 ：3.4
引用产品： bEnd.3 [BEND3] 细胞
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Construction and optimization of a coculture system of mouse brain microvascular endothelial cells and myelin debris (2023-06-10)
期刊：NEUROSCIENCE LETTERS
DOI：10.1016/j.neulet.2023.137345
影响因子 ：2.5
引用产品： bEnd.3 [BEND3] 细胞
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Curcumin in Vitro Neuroprotective Effects Are Mediated by p62/keap-1/Nrf2 and PI3K/AKT Signaling Pathway and Autophagy Inhibition (2023-08-31)
期刊：PHYSIOLOGICAL RESEARCH
DOI：10.33549/physiolres.935054
影响因子 ：2.1
引用产品： bEnd.3 [BEND3] 细胞 , HT22 细胞
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Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides (2022-08-06)
期刊：Journal of Extracellular Vesicles
影响因子 ：17.3
引用产品： bEnd.3 [BEND3] 细胞 , U-87 MG 细胞 , 293T [HEK-293T] 细胞 , A549 [A-549] 细胞 , SH-SY5Y [SHSY-5Y] 细胞 , Hep G2 细胞
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ROS-reactive PMS/PC drug delivery system improves new bone formation under diabetic conditions by promoting angiogenesis-osteogenesis coupling via down-regulating NOX2-ROS signalling axis (2022-11-07)
期刊：BIOMATERIALS
DOI：10.1016/j.biomaterials.2022.121900
影响因子 ：15.3
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Gold nanocluster & indocyanine green based triple-effective therapy for MRSA infected central nervous system (2022-04-04)
期刊：Applied Materials Today
DOI：10.1016/j.apmt.2022.101453
影响因子 ：8.3
引用产品： NCTC clone 929 [L 细胞, L-929] 细胞 , BV2 细胞 , bEnd.3 [BEND3] 细胞 , PUMC-HUVEC-T1
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Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression (2022-10-28)
期刊：Cell Death Discovery
DOI：10.1038/s41420-022-01222-y
影响因子 ：7.1
引用产品： bEnd.3 [BEND3] 细胞 , 人视网膜微血管内皮细胞 , bEnd.3 [BEND3]细胞专用培养基 , 人视网膜微血管内皮细胞完全培养基
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Biosynthetic Gas Vesicles Combined with Focused Ultrasound for Blood–Brain Barrier Opening (2022-12-28)
期刊：International Journal of Nanomedicine
影响因子 ：7.0
引用产品： bEnd.3 [BEND3] 细胞
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Podoplanin neutralization reduces thrombo-inflammation in experimental ischemic stroke by inhibiting interferon/caspase-1/GSDMD in microglia (2022-09-01)
期刊：Annals of Translational Medicine
影响因子 ：3.6
引用产品： bEnd.3 [BEND3] 细胞 , BV2 (DMEM) 细胞
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A bone-targeted engineered exosome platform delivering siRNA to treat osteoporosis (2021-09-17)
期刊：Bioactive Materials
DOI：10.1016/j.bioactmat.2021.09.015
影响因子 ：18.9
引用产品： MC3T3-E1 Subclone 14 细胞 , bEnd.3 [BEND3] 细胞 , RAW 264.7 细胞
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Design and screening of a novel neuropilin-1 targeted penetrating peptide for anti-angiogenic therapy in glioma (2021-01-27)
期刊：Life Sciences
影响因子 ：6.1
引用产品： bEnd.3 [BEND3] 细胞
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Nicotinamide mononucleotide (NMN) protects bEnd.3 cells against H2O2‐induced damage via NAMPT and the NF‐κB p65 signalling pathway (2021-02-09)
期刊：FEBS Open Bio
影响因子 ：2.6
引用产品： bEnd.3 [BEND3] 细胞
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The functional curcumin liposomes induce apoptosis in C6 glioblastoma cells and C6 glioblastoma stem cells in vitro and in animals (2017-02-17)
期刊：International Journal of Nanomedicine
影响因子 ：8.0
引用产品： bEnd.3 [BEND3] 细胞
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