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产品概述
| 名称 | CTLL-2 (小鼠T细胞) (STR鉴定正确) |
| 别称 | CTLL2; CTLL(2) |
| 种属 | 小鼠 |
| 生长特性 | 悬浮细胞 |
| 细胞形态 | 淋巴母细胞样 |
| 冻存条件 | 冻存液：90%FBS+10%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:2-1:3 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 1.该细胞为IL-2依赖型细胞，实验室可以常备 IL-2，发现细胞状态不好，散在细胞变多，细胞不生长等情况，以 100U/mL 的浓度添加 IL-2，培养 2-3 天后状态会有改善；2.该细胞冻存后再复苏需要2周左右时间来调整状态，调整过程中细胞碎片较多，具体操作请咨询技术支持，在技术支持的指导下进行，且该细胞冻存条件为90%FBS+10%DMSO。 |
| 背景描述 | CTLL-2细胞是一株具有细胞毒作用的IL-2依赖型的T-细胞株。 |
| 组织来源 | T细胞 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-1 |
| 受体表达情况 | interleukin 2 (IL-2), expressed |
| 保藏机构 | ATCC; TIB-214 DSMZ; ACC-27ECACC; 93042610 |
STR鉴定
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STR位点信息
18-3 16 6-7 17,20 5-5 17,18 X-1 28,29 1-2 19,20 7-1 26.2 8-1 16 1-1 17 19-2 13,14 15-3 22.3,23.3 12-1 17 6-4 18,19 4-2 19.3,20.3 3-2 14 2-1 15,16 13-1 16.1
11-2 16 17-2 14,15 -
STR鉴定图
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参考文献
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Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy (2024-03-18)
作者：Yuhao Jiang:1.School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China. ; Yanhao Zhang:1.School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China. ; Chao Liu:1.School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China. ; Jinyu Liu:1.School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China. ; Wenliang Xue:1.School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China. ; Zihao Wang:1.School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China. ; Xinsong Li:1.School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China. Electronic address: lixs@seu.edu.cn. ;
期刊：Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy
DOI：10.1016/j.jconrel.2024.03.016
影响因子 ：10.8
引用产品： CTLL-2 细胞
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Cholesterol removal improves performance of a model biomimetic system to co-deliver a photothermal agent and a STING agonist for cancer immunotherapy (2023-08-22)
作者：Lin Li:1.Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, China. ; Mengxing Zhang:1.Med-X center for Materials, College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China. ; Jing Li:1.Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, China. ; Tiantian Liu:1.Med-X center for Materials, College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China. ; Qixue Bao:1.Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, China. ; Xi Li:1.Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, China. ; Jiaying Long:1.Key Laboratory of Drug Targeting and Drug Delivery Systems of Ministry of Educat
期刊：Cholesterol removal improves performance of a model biomimetic system to co-deliver a photothermal agent and a STING agonist for cancer immunotherapy
DOI：10.1038/s41467-023-40814-9
影响因子 ：16.6
引用产品： CTLL-2 细胞 , A-375 细胞 , LLC [LL/2; LLC1] 细胞 , RAW 264.7 细胞
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Cuproptosis-immunotherapy using PD-1 overexpressing T cell membrane-coated nanosheets efficiently treats tumor (2023-09-09)
作者：Tiantian Liu:1.Med-X Center for Materials, College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China. ; Zehang Zhou:1.State Key Laboratory of Polymer Materials Engineering Polymer Research Institute of Sichuan University, College of Polymer Science and Engineering, Chengdu 610065, China. ; Mengxing Zhang:1.Med-X Center for Materials, College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China. ; Puxin Lang:1.Med-X Center for Materials, College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China. ; Jing Li:1.Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China. ; Zhenmi Liu:1.Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China. ; Zhirong Zhang:1.Key Laboratory of Drug Targeting and Drug Delivery Systems of Ministry of Educ
期刊：Cuproptosis-immunotherapy using PD-1 overexpressing T cell membrane-coated nanosheets efficiently treats tumor
DOI：10.1016/j.jconrel.2023.08.055
影响因子 ：10.8
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Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia (2022-12-15)
作者：Xue Zheng:1.State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, College of Life Sciences, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, Nankai University, Tongyan Road, Haihe Education Park, Tianjin 300350, China. ; Ke Sun:1.State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, College of Life Sciences, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, Nankai University, Tongyan Road, Haihe Education Park, Tianjin 300350, China. ; Yonghui Liu:1.State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, College of Life Sciences, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, Nankai University, Tongyan Road, Haihe Education Park, Tianjin 300350, China. ; Xiaona Yin:1.State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, College of Life Sciences, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, Nankai University, Tongyan Road, Haihe Education
期刊：Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia
DOI：10.1016/j.jconrel.2022.12.026
影响因子 ：11.5
引用产品： RAW 264.7 细胞 , DC2.4 细胞 , CTLL-2 细胞 , CTLL-2细胞专用培养基 , BV2 细胞 , U-87 MG 细胞
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