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![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0140-1.jpg)
![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0140-2.jpg)
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![LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0140-4.jpg)
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产品概述
| 名称 | LLC [LL/2; LLC1] (小鼠肺癌细胞) (STR鉴定正确) |
| 别称 | LL/2 (LLc1); LL/2(LLc1); LL/2; LL2; LLC1; LLC; Lewis lung carcinoma line 1; Lewis lung carcinoma; Lewis-Lung; Lewis Lung |
| 种属 | 小鼠 |
| 生长特性 | 半贴半悬 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | LLC细胞是小鼠Lewis肺癌细胞。 |
| 年龄（性别） | 不详 |
| 组织来源 | 肺 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肺癌细胞 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | Yes, in C57BL mice. |
| 抗原表达情况 | H-2b |
| 保藏机构 | ATCC; CRL-1642 BCRC; 60050 BCRJ; 0145 ECACC; 90020104 |
STR鉴定
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STR位点信息
18-3 15,16 6-7 15 5-5 16,17 X-1 25,26 1-2 18,19 7-1 27.2 8-1 16,17 1-1 15,16,17,18 19-2 13 15-3 24.3,25.3,26.3 12-1 17 6-4 18 4-2 21.3,23.3 3-2 13,14 2-1 16 13-1 18.1
11-2 13.3,14.3,15.3 17-2 14,15 -
STR鉴定图
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参考文献
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A method for predicting drugs that can boost the efficacy of immune checkpoint blockade (2024-03-18)
期刊：NATURE IMMUNOLOGY
DOI：10.1038/s41590-024-01789-x
影响因子 ：30.5
引用产品： LLC [LL/2; LLC1] 细胞
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UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment (2024-02-08)
期刊：Nature Communications
DOI：10.1038/s41467-024-45340-w
影响因子 ：16.6
引用产品： HCC827 细胞 , LLC [LL/2; LLC1] 细胞 , HFL1 细胞 , THP-1 细胞 , Ham's F-12K 培养基 , HFL1细胞完全培养基
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Nerve Growth Factor/Tyrosine Kinase A Receptor Pathway Enhances Analgesia in an Experimental Mouse Model of Bone Cancer Pain by Increasing Membrane Levels of δ-Opioid Receptors (2024-03-08)
期刊：ANESTHESIOLOGY
DOI：10.1097/ALN.0000000000004880
影响因子 ：8.8
引用产品： LLC [LL/2; LLC1] 细胞
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Bifunctional molecular probe targeting tumor PD-L1 enhances anti-tumor efficacy by promoting ferroptosis in lung cancer mouse model (2024-03-04)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.111781
影响因子 ：5.6
引用产品： LLC [LL/2; LLC1] 细胞 , 特级胎牛血清
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Dynamic Changes of the Gut Microbiota and Its Functional Metagenomic Potential during the Development of Non-Small Cell Lung Cancer (2024-03-28)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.6
引用产品： LLC [LL/2; LLC1] 细胞 , DMEM/F12 培养基
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Combinational delivery of TLR4 and TLR7/8 agonist enhanced the therapeutic efficacy of immune checkpoint inhibitors to colon tumor (2024-03-20)
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-024-04966-6
影响因子 ：4.3
引用产品： 4T1 细胞 , LLC [LL/2; LLC1] 细胞
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Liquid Metal Nanoplatform Based Autologous Cancer Vaccines (2023-05-30)
期刊：ACS Nano
影响因子 ：17.1
引用产品： LLC [LL/2; LLC1] 细胞
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Generation of whole tumor cell vaccine for on-demand manipulation of immune responses against cancer under near-infrared laser irradiation (2023-07-26)
期刊：Nature Communications
DOI：10.1038/s41467-023-40207-y
影响因子 ：16.6
引用产品： 4T1 细胞 , CT26.WT 细胞 , LLC [LL/2; LLC1] 细胞
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Cholesterol removal improves performance of a model biomimetic system to co-deliver a photothermal agent and a STING agonist for cancer immunotherapy (2023-08-22)
期刊：Nature Communications
DOI：10.1038/s41467-023-40814-9
影响因子 ：16.6
引用产品： CTLL-2 细胞 , A-375 细胞 , LLC [LL/2; LLC1] 细胞 , RAW 264.7 细胞
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Autologous-cancer-cryoablation-mediated nanovaccine augments systematic immunotherapy (2023-02-21)
期刊：Materials Horizons
影响因子 ：13.3
引用产品： LLC [LL/2; LLC1] 细胞
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Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner (2023-02-03)
期刊：Cancer Immunology Research
DOI：10.1158/2326-6066.CIR-22-0439
影响因子 ：10.1
引用产品： Jurkat, Clone E6-1 细胞 , RKO 细胞 , CT26.WT 细胞 , B16-F10 细胞 , MC38 细胞 , 4T1 细胞 , LLC [LL/2; LLC1] 细胞 , Hepa 1-6 细胞 , YAC-1 细胞 , 293T [HEK-293T] 细胞 , AAV-293 细胞 , STR鉴定
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Metal-Phenolic network pH-Sensitive Nanoparticle-Enabled Chemo/Chemodynamic therapy for lung cancer (2023-06-08)
期刊：MATERIALS & DESIGN
DOI：10.1016/j.matdes.2023.112072
影响因子 ：8.4
引用产品： LLC [LL/2; LLC1] 细胞 , A549 [A-549] 细胞
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Hypoxia-induced AFAP1L1 regulates pathological neovascularization via the YAP-DLL4-NOTCH axis (2023-09-22)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04503-x
影响因子 ：7.4
引用产品： A549 [A-549] 细胞 , LLC [LL/2; LLC1] 细胞
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Radiation-Induced Bystander Effect on the Genome of Bone Marrow Mesenchymal Stem Cells in Lung Cancer (2023-04-10)
期刊：ANTIOXIDANTS & REDOX SIGNALING
影响因子 ：6.6
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H446 [H446] 细胞 , LLC [LL/2; LLC1] 细胞
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E74‑like ETS transcription factor 5 facilitates cell proliferation through regulating the expression of adenomatous polyposis coli 2 in non‑small cell lung cancer (2023-07-11)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
影响因子 ：5.4
引用产品： LLC [LL/2; LLC1] 细胞
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Study the inhibitory effect and mechanism of the ethanol extract of deziyangxin on LLC cells (2023-07-27)
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e18712
影响因子 ：4.0
引用产品： LLC [LL/2; LLC1] 细胞 , GES-1 细胞
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Sambucus adnata Polysaccharide SPS-1 Inhibits Growth of Transplanted Lung Cancer via Polarizing Tumor Associated Macrophage From M2 into M1 (2023-07-10)
期刊：Natural Product Communications
影响因子 ：1.8
引用产品： LLC [LL/2; LLC1] 细胞
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Intelligent triggering of nanomicelles based on a ROS-activated anticancer prodrug and photodynamic therapy (PDT)-synergistic therapy for lung cancers (2022-08-03)
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2022.114622
影响因子 ：7.1
引用产品： MCF7 [MCF-7] 细胞 , LLC [LL/2; LLC1] 细胞
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Reassembling of albumin-bound paclitaxel mitigates myelosuppression and improves its antitumoral efficacy via neutrophil-mediated targeting drug delivery (2002-02-20)
期刊：Drug Delivery
DOI：10.1080/10717544.2022.2046892
影响因子 ：6.0
引用产品： LLC [LL/2; LLC1] 细胞
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Nanomicelle-Microsphere Composite as a Drug Carrier to Improve Lung-Targeting Specificity for Lung Cancer (2002-02-20)
期刊：Pharmaceutics
DOI：10.3390/pharmaceutics14030510
影响因子 ：5.4
引用产品： A549 [A-549] 细胞 , LLC [LL/2; LLC1] 细胞
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Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway (2022-09-17)
期刊：NEUROPHARMACOLOGY
DOI：10.1016/j.neuropharm.2022.109254
影响因子 ：5.3
引用产品： LLC [LL/2; LLC1] 细胞
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Shashen-Maidong Decoction inhibited cancer growth under intermittent hypoxia conditions by suppressing oxidative stress and inflammation (2022-09-02)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.2
引用产品： LLC [LL/2; LLC1] 细胞
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Black phosphorus nanoparticles for dual therapy of non-small cell lung cancer (2002-02-20)
期刊：Journal Of Drug Targeting
DOI：10.1080/1061186X.2022.2032093
影响因子 ：5.0
引用产品： LLC [LL/2; LLC1] 细胞 , NCI-H1299 细胞
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Alterations of lung microbiota in patients with non-small cell lung cancer (2003-02-20)
期刊：Bioengineered
DOI：10.1080/21655979.2022.2045843
影响因子 ：4.9
引用产品： LLC [LL/2; LLC1] 细胞
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Transplantation of feces from mice with Alzheimers disease promoted lung cancer growth (2001-02-20)
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2022.01.078
影响因子 ：3.1
引用产品： LLC [LL/2; LLC1] 细胞
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Luteolin Relieves Lung Cancer-Induced Bone Pain by Inhibiting NLRP3 Inflammasomes and Glial Activation in the Spinal Dorsal Horn in Mice (2021-12-25)
期刊：Phytomedicine
DOI：10.1016/j.phymed.2021.153910
影响因子 ：7.9
引用产品： LLC [LL/2; LLC1] 细胞
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Erianin inhibits human lung cancer cell growth via PI3K/Akt/mTOR pathway in vitro and in vivo (2003-01-20)
期刊：Phytotherapy Research
DOI：10.1002/ptr.7154
影响因子 ：7.2
引用产品： NCI-H1975 细胞 , LLC [LL/2; LLC1] 细胞 , A549 [A-549] 细胞 , 293A 细胞
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DHA/EPA-Enriched Phosphatidylcholine Suppresses Tumor Growth and Metastasis via Activating Peroxisome Proliferator-Activated Receptor γ in Lewis Lung Cancer Mice (2001-01-20)
期刊：Journal Of Agricultural And Food Chemistry
影响因子 ：6.1
引用产品： LLC [LL/2; LLC1] 细胞
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Jolkinolide B inhibits proliferation or migration and promotes apoptosis of MCF-7 or BT-474 breast cancer cells by downregulating the PI3K-Akt pathway (2008-01-20)
期刊：Journal Of Ethnopharmacology
影响因子 ：5.4
引用产品： MCF7 [MCF-7] 细胞 , LLC [LL/2; LLC1] 细胞
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Depression promotes lung carcinoma progression by regulating the tumor microenvironment in tumor-bearing models of C57BL/6J mice (2005-01-20)
期刊：Neuroscience Letters
DOI：10.1016/j.neulet.2021.135851
影响因子 ：2.5
引用产品： LLC [LL/2; LLC1] 细胞
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