产品中心Cell Resources
联系我们CONTACT US
- 400-999-210024小时服务热线
产品概述
名称 | DC2.4 (小鼠骨髓来源树突状细胞) (STR鉴定正确) |
别称 | DC 2.4 |
种属 | 小鼠 |
生长特性 | 贴壁细胞,少量悬浮 |
细胞形态 | 圆形;梭形,胞突呈分枝状 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3天/次 |
注意事项 | 圆形贴壁,少量贴壁细胞伸展开,少量悬浮。密度低时漂浮较少,密度高时,漂浮比例增大,漂浮部分也可以培养。 |
背景描述 | DC2.4是通过用表达小鼠粒细胞-巨噬细胞-CSF(GM-CSF)和myc和raf致癌基因的逆转录病毒载体转导C57BL/6小鼠的骨髓分离物而产生的永生化小鼠树突状细胞。DC2.4表现出树突细胞的特征,包括细胞形态和树突细胞特异性标记物的表达,以及吞噬MHC I类和II类分子并在其上呈递外源性抗原的能力。 |
细胞类型 | 转化细胞系 |
生物安全等级 | BSL-1 |
STR鉴定
-
STR位点信息
18-3 15,16 6-7 17 5-5 17,18 X-1 28 1-2 19 7-1 26.2,27.2 8-1 16 1-1 17 19-2 13 15-3 22.3,23.3 12-1 17 6-4 18 4-2 20.3,21.3 3-2 14 2-1 16 13-1 17.1
11-2 16,17 17-2 16 -
STR鉴定图
参考文献
-
Nanoadjuvant-triggered STING activation evokes systemic immunotherapy for repetitive implant-related infections (2024-01-24)
作者:Dongdong Xu:1.Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, PR China. ; Jun Hu:1.Department of Laboratory Medicine, Long Hua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, PR China. ; Jiawei Mei:1.Department of Orthopedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, PR China. ; Jun Zhou:1.Department of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, PR China. ; Zhengxi Wang:1.Department of Orthopedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, PR China. ; Xudong Zhang:1.Department of Orthopedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Sci
期刊:Nanoadjuvant-triggered STING activation evokes systemic immunotherapy for repetitive implant-related infections
DOI:10.1016/j.bioactmat.2024.01.020
影响因子 :18.9
引用产品: DC2.4 细胞 , 小鼠骨髓树突状细胞 (未成熟DC细胞)
-
Tailoring therapeutics via a systematic beneficial elements comparison between photosynthetic bacteria-derived OMVs and extruded nanovesicles (2024-02-26)
作者:Tingshan Xiao:1.College of Pharmaceutical Science, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, 071002, China. ; 2.State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding, 071002, China. ; Yichuan Ma:1.State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding, 071002, China. ; 2.College of Chemistry & Materials Science, Hebei University, Baoding, 071002, China. ; Ziyang Zhang:1.College of Pharmaceutical Science, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, 071002, China. ; 2.State Key Laboratory of New Pharmaceutical Preparations an
期刊:Tailoring therapeutics via a systematic beneficial elements comparison between photosynthetic bacteria-derived OMVs and extruded nanovesicles
DOI:10.1016/j.bioactmat.2024.02.025
影响因子 :18.9
引用产品: DC2.4 细胞
-
Cancer cell membrane proteins-encapsulated nanovaccine enhances cancer immunotherapy and prevention by provoking antigen-specific cellular immunity via the dendritic cell-targeted delivery (2024-01-06)
作者:Xingyu Luo: 1.Key Laboratory of Food Nutrition and Functional Food of Hainan Province, School of Food Science and Engineering, Hainan University, Haikou 570228, China; Xiaolu Chen: 1.Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Science, Haikou 570100, China; Rongying Ma: 1.Key Laboratory of Food Nutrition and Functional Food of Hainan Province, School of Food Science and Engineering, Hainan University, Haikou 570228, China; Zhaoming Fu: 1.Key Laboratory of Food Nutrition and Functional Food of Hainan Province, School of Food Science and Engineering, Hainan University, Haikou 570228, China; Zuwei Liu: 1.Key Laboratory of Food Nutrition and Functional Food of Hainan Province, School of Food Science and Engineering, Hainan University, Haikou 570228, China; Qianhong Su: 1.Key Laboratory of Food Nutrition and Functional Food of Hainan Province, School of Food Science and Engineering, Hainan University, Haikou 570228, China; Huiling Fu: 1.Key Laborator
期刊:Cancer cell membrane proteins-encapsulated nanovaccine enhances cancer immunotherapy and prevention by provoking antigen-specific cellular immunity via the dendritic cell-targeted delivery
影响因子 :15.1
-
Pre-Induced ICD Membrane-Coated Carrier-Free Nanoparticles for the Personalized Lung Cancer Immunotherapy (2023-03-18)
作者:Shilin Li:1.CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, P. R. China. ; 2.University of Chinese Academy of Sciences, Beijing, 100049, P. R. China. ; Shasha Jiang:1.Department of Thoracic Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing, 100853, P. R. China. ; 2.Postgraduate School, Medical school of Chinese PLA, Beijing, 100853, P. R. China. ; Muhammad Saif Ur Rahman:1.Institute for Advanced Study, Shenzhen University, Shenzhen, 518060, P. R. China. ; Jie Mei:1.CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing, 100190, P. R. China. ; 2.University of Chinese Academy of Sciences, Beijing, 100049, P. R. China. ; Xinlian Wang:1.CAS Key Laboratory for Biomedical Effects of Nanomater
期刊:Pre-Induced ICD Membrane-Coated Carrier-Free Nanoparticles for the Personalized Lung Cancer Immunotherapy
影响因子 :12.4
引用产品: DC2.4 细胞
-
Endogenous/Exogenous Nanovaccines Synergistically Enhance Dendritic Cell-Mediated Tumor Immunotherapy (2023-02-18)
作者:Yu Zhang:1.Nanjing Stomatological Hospital, Medical School of Nanjing University, 30 Zhongyang Road, Nanjing, Jiangsu, 210008, P. R. China. ; Qiang Li:1.Nanjing Stomatological Hospital, Medical School of Nanjing University, 30 Zhongyang Road, Nanjing, Jiangsu, 210008, P. R. China. ; Meng Ding:1.Nanjing Stomatological Hospital, Medical School of Nanjing University, 30 Zhongyang Road, Nanjing, Jiangsu, 210008, P. R. China. ; Weijun Xiu:1.Key Laboratory for Organic Electronics and Information Displays, Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials, Jiangsu National Synergetic Innovation Centre for Advanced Materials, Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, Nanjing, Jiangsu, 210023, P. R. China. ; Jingyang Shan:1.Department of Neurology, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518000, P. R. China. ; Lihui Yuwen:1.Key Laboratory f
期刊:Endogenous/Exogenous Nanovaccines Synergistically Enhance Dendritic Cell-Mediated Tumor Immunotherapy
影响因子 :10.0
-
Delivery of Mrna Vaccine with 1, 2-diesters-derived Lipids Elicits Fast Liver Clearance for Safe and Effective Cancer Immunotherapy. (2023-11-21)
作者:Yuandong Xu:1.Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital Sun Yat-sen University, No. 628, Zhenyuan Road, Guangming District, Shenzhen, Guangdong, CN518107, China. ; Yuexiao Hu:1.Key Laboratory for Green Chemical Process of Ministry of Education, Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, Hubei, CN430205, China. ; Heng Xia:1.Scientific Research Center, The Seventh Affiliated Hospital Sun Yat-sen University, No. 628, Zhenyuan Road, Guangming District, Shenzhen, Guangdong, CN518107, China. ; Shiqiang Zhang:1.Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders Center, The Seventh Affiliated Hospital Sun Yat-sen University, No. 628, Zhenyuan Road, Guangming District, Shenzhen, Guangdong, CN518107, China. ; Hanqi Lei:1.Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders
期刊:Delivery of Mrna Vaccine with 1, 2-diesters-derived Lipids Elicits Fast Liver Clearance for Safe and Effective Cancer Immunotherapy.
影响因子 :10.0
引用产品: B16 细胞 , RM-1 细胞 , DC2.4 细胞 , 293 [HEK-293] 细胞
-
PTT/ PDT-induced microbial apoptosis and wound healing depend on immune activation and macrophage phenotype transformation (2023-06-25)
作者:Haoyu Chen:1.College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, 700 Changcheng Road, Qingdao, 266109, China. ; Lijuan Wu:1.Innovation Platform of Marine Drug Screening & Evaluation, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266100, China. ; Tianyi Wang:1.College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, 700 Changcheng Road, Qingdao, 266109, China. ; Fenglan Zhang:1.College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, 700 Changcheng Road, Qingdao, 266109, China. ; Junyao Song:1.University of Health and Rehabilitation Sciences, Qingdao 266113, Shandong, China. ; Jun Fu:1.Bassars college of future agricultural science and technology, Qingdao Agricultural University, 700 Changcheng Road, Qingdao, 266109, China. Electronic address: fujun8@mail.sysu.edu.cn. ; Xiaoying Kong:1.College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, 700 Ch
期刊:PTT/ PDT-induced microbial apoptosis and wound healing depend on immune activation and macrophage phenotype transformation
DOI:10.1016/j.actbio.2023.06.025
影响因子 :9.7
-
Extracellular vesicles hybrid plasmid-loaded lipid nanovesicles for synergistic cancer immunotherapy (2023-10-27)
作者:Qing Tong:1.National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; 2.Department of Gynecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Kexin Li:1.National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; 2.Department of Gynecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Fanwei Huang:1.National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical Col
期刊:Extracellular vesicles hybrid plasmid-loaded lipid nanovesicles for synergistic cancer immunotherapy
DOI:10.1016/j.mtbio.2023.100845
影响因子 :8.2
引用产品: DC2.4 细胞
-
Doxorubicin-Loaded Platelet Decoys for Enhanced Chemoimmunotherapy Against Triple-Negative Breast Cancer in Mice Model (2023-06-30)
作者:Hang Dong:1.Department of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China. ; Meng Gao:1.Department of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China. ; Lu Lu:1.Department of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China. ; Rong Gui:1.Department of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China. ; Yunfeng Fu:1.Department of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China. ;
期刊:Doxorubicin-Loaded Platelet Decoys for Enhanced Chemoimmunotherapy Against Triple-Negative Breast Cancer in Mice Model
影响因子 :8.0
引用产品: 特级胎牛血清 , RPMI-1640 培养基 , DC2.4 细胞 , MDA-MB-231 细胞
-
Cascade catalysis-coordinated nanorobot toward synergistic cancer chemoimmunotherapy (2023-08-30)
作者:Ruirui Guo:1.Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China. yuanlu@tsinghua.edu.cn. ; Bin Wang:1.Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China. yuanlu@tsinghua.edu.cn. ; Dong Liu:1.Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China. yuanlu@tsinghua.edu.cn. ; Yanjie Huang:1.Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China. yuanlu@tsinghua.edu.cn. ; Yuan Lu:1.Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China. yuanlu@tsinghua.edu.cn. ;
期刊:Cascade catalysis-coordinated nanorobot toward synergistic cancer chemoimmunotherapy
影响因子 :7.0
-
Interferon-γ regulates immunosuppression in septic mice by promoting the Warburg effect through the PI3K/AKT/mTOR pathway (2023-07-11)
作者:Xu-Zhe Fu:1.Department of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, China. ; Yu Wang:1.Department of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, China. wangy8@sj-hospital.org. ;
期刊:Interferon-γ regulates immunosuppression in septic mice by promoting the Warburg effect through the PI3K/AKT/mTOR pathway
DOI:10.1186/s10020-023-00690-x
影响因子 :5.7
引用产品: DC2.4 细胞 , L-谷氨酰胺溶液 (200mM),100× , 青霉素-链霉素溶液 (双抗),100× , MEM非必需氨基酸溶液 (NEAA),100× , β-巯基乙醇 (55mM),1000× , 特级胎牛血清
-
Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia (2022-12-15)
作者:Xue Zheng:1.State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, College of Life Sciences, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, Nankai University, Tongyan Road, Haihe Education Park, Tianjin 300350, China. ; Ke Sun:1.State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, College of Life Sciences, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, Nankai University, Tongyan Road, Haihe Education Park, Tianjin 300350, China. ; Yonghui Liu:1.State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, College of Life Sciences, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, Nankai University, Tongyan Road, Haihe Education Park, Tianjin 300350, China. ; Xiaona Yin:1.State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, College of Life Sciences, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, Nankai University, Tongyan Road, Haihe Education
期刊:Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia
DOI:10.1016/j.jconrel.2022.12.026
影响因子 :11.5
引用产品: RAW 264.7 细胞 , DC2.4 细胞 , CTLL-2 细胞 , CTLL-2细胞专用培养基 , BV2 细胞 , U-87 MG 细胞
-
Dendritic cells originating exosomal miR-193b-3p induces regulatory T cells to alleviate liver transplant rejection (2022-12-21)
作者:Bin Cui:1.Liver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 101100, China; Department of Neurosurgery, Aviation General Hospital, Beijing 100012, China. ; Xiao-Jie Chen:1.Liver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 101100, China; Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing 101100, China; National Clinical Research Center for Digestive Diseases, Beijing 101100, China. ; Jie Sun:1.Liver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 101100, China; Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing 101100, China; National Clinical Research Center for Digestive Diseases, Beijing 101100, China. ; Shi-Peng Li:1.Liver Transplantation Center, Beijing Friendship Hospital, Capital Medical University, Beijing 101100, China; Clinical Center for Pediatric Liver Transplantation,
期刊:Dendritic cells originating exosomal miR-193b-3p induces regulatory T cells to alleviate liver transplant rejection
DOI:10.1016/j.intimp.2022.109541
影响因子 :5.7
引用产品: DC2.4 细胞
-
Transcriptomic analysis reveal the responses of dendritic cells to VDBP (2003-02-20)
作者:Biwei Cao:1.Department of Tuina and Rehabilitation Medicine, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China. ; 2.Department of Tuina and Rehabilitation Medicine, Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, 430061, China. ; 3.Department of Tuina and Rehabilitation Medicine, Hubei Province Academy of Traditional Chinese Medicine, Wuhan, 430074, China. ; Tao Wen:1.Department of Tuina and Rehabilitation Medicine, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China. ; 2.Department of Tuina and Rehabilitation Medicine, Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, 430061, China. ; 3.Department of Tuina and Rehabilitation Medicine, Hubei Province Academy of Traditional Chinese Medicine, Wuhan, 430074, China. ; Meng Wei:1.Department of Tuina and Rehabilitation Medicine, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China. ; 2.Department of Tuina and Rehabilit
期刊:Transcriptomic analysis reveal the responses of dendritic cells to VDBP
DOI:10.1007/s13258-022-01234-z
影响因子 :2.1
引用产品: DC2.4 细胞
FAQs
Q:{{item.question}}
A:
产品资料
识别码示意图