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产品概述
名称 | JEG-3 (人绒毛膜癌细胞) (STR鉴定正确) |
别称 | Jeg-3; JEG3; Jeg3; jeg3 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | JEG-3细胞是一株超三倍体人类细胞株。JEG-3细胞的典型染色体数为71,发生率为34%,多倍体率为2.6%。t(4;11)(p15;q13),i(13q),t(10p15q),del(18)(q21)和6个其他标记在大多数细胞中常见,另有两个标记在一些细胞中可见,在一个N14和两个N22中可见大卫星。N2、N5和N9有4个拷贝,而N7、N13、N18、N21和X为单拷贝,Q-带检测法可以检测到单个Y染色体。 |
年龄(性别) | 男性;胎儿 |
组织来源 | 胎盘病变;绒毛膜癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 其它肿瘤细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~24-36 hours |
致瘤性 | Yes, in nude mice; forms malignant tumor consistent with choriocarcinoma. |
基因表达情况 | human chorionic gonadotropin (hCG), human chorionic somatomammotropin (placental lactogen); progesterone |
保藏机构 | ATCC; HTB-36 BCRC; 60428 BCRJ; 0123 DSMZ; ACC-463 ECACC; 92120308 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 11,12 D2S1338 24 D3S1358 15,16 D5S818 10,11 D7S820 10,12 D8S1179 12 D13S317 9,11 D16S539 13,14 D18S51 14 D19S433 13,15 D21S11 30 FGA 23,24 PentaD 9,12 PentaE 8,12 TH01 9,9.3 TPOX 8 vWA 16 D6S1043 11 D12S391 17,24 D2S441 14,15 -
STR鉴定图
参考文献
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Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway(2024/01/04)
作者:Jing Yang, Longfei Li, Linlin Wang
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04831-y
影响因子 :7.400
引用产品:CL-0127
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Talin1 regulates endometrial adhesive capacity through the Ras signaling pathway(2021/03/09)
作者:Saiqiong Chen , Bo Liu , Jingjing Li
期刊:Life Sciences
影响因子 :6.780
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Hsa_circ_0001326 inhibited the proliferation, migration, and invasion of trophoblast cells via miR-145-5p/TGFB2 axis(2023/01/20)
作者:Meiyu Song, Peng Xu, Li Wang
期刊:AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影响因子 :3.600
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IGF2BP3 participates in the pathogenesis of recurrent spontaneous abortion by regulating ferroptosis(2024/05/30)
作者:Fangfang Dai, Yuwei Zhang, Jie Zhang
期刊:JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影响因子 :3.400
引用产品:CL-0127
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Evaluation of transport mechanisms of methotrexate in human choriocarcinoma cell lines by LC-MS/MS(2024/05/29)
作者:Mengru Bai, Qian Shen, Yong Wu
期刊:JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
DOI:10.1016/j.jpba.2024.116268
影响因子 :3.400
引用产品:CL-0127
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IL‑1β‑induced pentraxin 3 inhibits the proliferation, invasion and cell cycle of trophoblasts in preeclampsia and is suppressed by IL‑1β antagonists(2022/02/07)
作者:Xiaoxi Wang, Jing Zhang, Jing Ji
期刊:Molecular Medicine Reports
影响因子 :3.400
引用产品:CL-0127
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The Possible Involvement of miR-371a-5p Regulating XIAP in the Pathogenesis of Recurrent Pregnancy Loss:(2019/2/28)
作者:Erqiu Du, Yuming Cao, Chun Feng
期刊:Reproductive Sciences
影响因子 :2.900
引用产品:CL-0127
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Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia(2023/06/05)
作者:Ruijing Chang, Yuan Su, Hongfang Kong
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-023-00774-3
影响因子 :2.600
引用产品:CL-0127
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miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway(2020/2/26)
作者:Fengyan Gong, Wei Chai, Junwei Wang
期刊:Acta Histochemica
DOI:10.1016/j.acthis.2020.151527
影响因子 :2.500
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