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产品概述
| 名称 | HTR-8-Svneo (人绒毛膜滋养层细胞) (STR鉴定正确) |
| 别称 | HTR-8/SV neo; HTR-8/SV-neo; HTR8/SVneo; HTR8svn |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:3 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | The HTR-8-Svneo cell line was derived by transfecting the cells that grew out of chorinic villi explants of human first-trimester placenta with the gene encoding for simian virus 40 large T antigen. |
| 年龄（性别） | 女性；6-12周龄胚胎 |
| 组织来源 | 胎盘 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | No (tested in soft agar and nude mice). |
| 抗原表达情况 | cytokeratin-7+; insulin-like growth factor (IGF)-II+; NDOG-5 (placental alkaline phosphatase (PLAP) antibody) +; proliferating cell nuclear antigen (PCNA)+; human leukocyte antigen framework antigen (W6/32)+; integrin subunits alpha 1, alpha 3, alpha |
| 保藏机构 | ATCC; CRL-3271 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 23,24 D3S1358 16 D5S818 12 D7S820 12 D8S1179 12,15 D13S317 9,12 D16S539 11,13 D18S51 13 D19S433 14,15 D21S11 29,30 FGA 21,23 PentaD 9,12 PentaE 7,17 TH01 6,9.3 TPOX 8 vWA 13,18 D6S1043 14,19 D12S391 19 D2S441 11 -
STR鉴定图
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参考文献
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Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway(2024/01/04)
作者：Jing Yang, Longfei Li, Linlin Wang
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04831-y
影响因子 ：7.400
引用产品：CL-0765
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Calcium/calmodulin dependent protein kinase IV in trophoblast cells under insulin resistance: functional and metabolomic analyses(2023/06/29)
作者：Ling Li, Li Li, Ying Shao
期刊：MOLECULAR MEDICINE
DOI：10.1186/s10020-023-00669-8
影响因子 ：5.700
引用产品：CL-0765
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NANOG regulate the JAK/STAT3 pathway to promote trophoblast cell migration and epithelial-mesenchymal transition (EMT) in hypertensive disorders of pregnancy (HDP) through protein interaction with CDK1(2024/05/26)
作者：Jing Ma, Mingchang Liu, Zhuo Chen
期刊：AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影响因子 ：3.600
引用产品：CL-0765
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AQP9 causes recurrent spontaneous abortion by inhibiting trophoblast cell EMT and invasion through the PI3K/AKT pathway(2023/08/21)
作者：Nana Ma, Bo Liu, Yufu Jin
期刊：BIOLOGY OF REPRODUCTION
影响因子 ：3.600
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Inhibition of the endoplasmic reticulum stress-associated IRE-1 pathway alleviates preterm birth(2024/03/26)
作者：Liyin Qiu, Hui Liu, Shali Chen
期刊：AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影响因子 ：3.600
引用产品：CL-0765
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HNRNPC mediated m6A methylation of 5-Methyltetrahydrofolate-homocysteine methyltransferase and involved in the occurrence of recurrent spontaneous abortion(2023/10/04)
作者：Mengting Zhang, Nana Huang, Yue Gao
期刊：JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影响因子 ：3.400
引用产品：CL-0765
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Establishment of a placental lncRNA-mRNA expression network for early-onset preeclampsia(2024/04/27)
作者：Ya Chen, Ying Zhang, Siyu Xie
期刊：BMC Pregnancy and Childbirth
DOI：10.1186/s12884-024-06481-4
影响因子 ：3.100
引用产品：CL-0765
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Mechanisms of YAP1-mediated trophoblast ferroptosis in recurrent pregnancy loss(2024/03/25)
作者：Liping Chen, Fangfang Dai, Yanjie Huang
期刊：JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
DOI：10.1007/s10815-024-03096-8
影响因子 ：3.100
引用产品：CL-0765
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MiR-135a-5p regulates window of implantation by suppressing pinopodes development and decidualization of endometrial stromal cells(2024/03/21)
作者：Yunan He, Ying Ju, Hui Lei
期刊：JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
DOI：10.1007/s10815-024-03088-8
影响因子 ：3.100
引用产品：CL-0765
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Circ_FOXP1 promotes the growth and survival of high glucose-treated human trophoblast cells through the regulation of miR-508-3p/SMAD family member 2 pathway(2022/09/28)
作者：Mingqun Li, Yuqin Huang, Hongli Xi
期刊：ENDOCRINE JOURNAL
影响因子 ：2.860
引用产品：CL-0765
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MicroRNA-206 Contributes to the Progression of Preeclampsia by Suppressing the Viability and Mobility of Trophocytes via the Inhibition of AGTR1(2023/10/31)
作者：WeiWei Mo, Jiaxi Jin, Xuexin Wang
期刊：PHYSIOLOGICAL RESEARCH
DOI：10.33549/physiolres.935131
影响因子 ：2.100
引用产品：CL-0765
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Knockdown of TXNIP alleviates gestational diabetes mellitus by activating autophagy to regulate cell proliferation and apoptosis in high glucose-treated trophoblasts(2023/12/19)
作者：Ying Gu, Minkai Cao, Yu Chen
期刊：Reproductive Biology
DOI：10.1016/j.repbio.2023.100841
影响因子 ：2.100
引用产品：CL-0765
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Protective Effects of Paeoniflorin Against Inflammation and Oxidative Stress in Rats with Gestational Diabetes Mellitus via Inhibiting the RhoA/ROCK Signaling Pathway(2024/01/02)
作者：Chengkun Yuan, Yan Gao, Jinglu Yu
期刊：Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy
DOI：10.1007/s43450-023-00505-4
影响因子 ：1.600
引用产品：CL-0765
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COLEC12 expression participates in trophoblast insulin resistance, and reverses celecoxib-mediated inhibition of COX2-PGE2 axis in gestational diabetes(2023/06/05)
作者：Beibei Jin, Mi Hu, Jie Chen
期刊：TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
影响因子 ：0.600
引用产品：CL-0765
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产品资料
识别码示意图
![CCRF-CEM [CCRF CEM] (人急性淋巴细胞白血病T淋巴细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0058-1.jpg)
