产品中心Cell Resources
联系我们CONTACT US
400-999-210024小时服务热线
产品概述
| 名称 | ME-180 (人子宫颈表皮癌细胞) (STR鉴定正确) |
| 别称 | Me-180; ME 180; ME180 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:8 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | ME-180细胞来源于一个细胞集落不规则没有显著角质化的侵染性鳞状细胞癌。单层培养的ME-180细胞间可以观察到带状连接，也注意到有细胞质张力丝。1970年，发现支原体污染并去除。TNF-α抑制ME-180细胞的生长；ME-180细胞含有人乳头瘤病毒DNA，与HPV-39的同源性高于HPV-18。 |
| 年龄（性别） | 女性；66岁 |
| 组织来源 | 宫颈表皮样癌网膜转移灶 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 宫颈癌细胞 |
| 生物安全等级 | BSL-2 |
| 倍增时间 | ~36 hours |
| 致瘤性 | Yes, in nude mice; forms well differentiated epidermoid carcinoma (grade I). |
| 抗原表达情况 | Blood Type A; Rh+; HLA A1, A11, B5(+/-), B40 |
| 基因表达情况 | Oncogenes: p53+; pRB+ |
| 保藏机构 | ATCC; HTB-33 |
STR鉴定
-
STR位点信息
Amelogenin X CSF1PO 11 D2S1338 18 D3S1358 16 D5S818 12 D7S820 9,10 D8S1179 14 D13S317 11,13 D16S539 12,13 D18S51 12 D19S433 13,15.2 D21S11 30,31 FGA 23 PentaD 9,14 PentaE 12,14 TH01 8,9.3 TPOX 8,10 vWA 15,17 D6S1043 11 D12S391 18,20 D2S441 11,12 -
STR鉴定图
-
参考文献
-
Significance of Immunogenic Cell Death-Related Prognostic Gene Signature in Cervical Cancer Prognosis and Anti-Tumor Immunity (2023-05-21)
作者：Shan Jiang:1.Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, People's Republic of China. ; 2.College of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, People's Republic of China. ; Zhaolei Cui:1.Laboratory of Biochemistry and Molecular Biology Research, Department of Clinical Laboratory, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, People's Republic of China. ; Jianfeng Zheng:1.Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, People's Republic of China. ; Qiaoling Wu:1.Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, People's Republic of China. ; Haijuan Yu:1.Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014,
期刊：Significance of Immunogenic Cell Death-Related Prognostic Gene Signature in Cervical Cancer Prognosis and Anti-Tumor Immunity
影响因子 ：4.5
-
LINC00460 knockdown sensitizes cervical cancer to cisplatin by downregulating TGFBI (2023-12-28)
作者：Ping Tian:1.Xinyang Vocational and Technical College, Xinyang, China. ; Yuanyuan Feng:1.Department of Gynaecology and Obstetrics, Xinyang Central Hospital, Xinyang, China. ; Ling Tao:1.Xinyang Vocational and Technical College, Xinyang, China. ;
期刊：LINC00460 knockdown sensitizes cervical cancer to cisplatin by downregulating TGFBI
影响因子 ：3.0
-
OTX1 promotes tumorigenesis and progression of cervical cancer by regulating the Wnt signaling pathway (2022-09-29)
作者：Limin Zhou:1.Department of Gynecology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Hongshan, Wuhan, Hubei 430070, P.R. China. ; Hongying Li:1.Department of Gynecology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Hongshan, Wuhan, Hubei 430070, P.R. China. ; Dunlan Zhang:1.Department of Gynecology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Hongshan, Wuhan, Hubei 430070, P.R. China. ; Lu Chen:1.Department of Gynecology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Hongshan, Wuhan, Hubei 430070, P.R. China. ; Hong Dong:1.Department of Gynecology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technolog
期刊：OTX1 promotes tumorigenesis and progression of cervical cancer by regulating the Wnt signaling pathway
影响因子 ：4.1
-
LncRNA Opa interacting protein 5-antisense RNA 1 (OIP5-AS1) promotes the migration, invasion and epithelial-mesenchymal transition (EMT) through targeting miR-147a/insulin-like growth factor 1 receptor (IGF1R) pathway in cervical cancer tissues and c (2003-02-20)
作者：Limei Zhang:1.Department of Obstetrics and Gynecology, Affiliated Hospital of Beihua University, Jilin City, China. ; Yufei Cai:1.Department of Obstetrics and Gynecology, Affiliated Hospital of Beihua University, Jilin City, China. ; Chenchen Tian:1.Department of Obstetrics and Gynecology, Affiliated Hospital of Beihua University, Jilin City, China. ; Yanru Li:1.Department of Obstetrics and Gynecology, Affiliated Hospital of Beihua University, Jilin City, China. ; Kuili Ma:1.Department of Obstetrics and Gynecology, Affiliated Hospital of Beihua University, Jilin City, China. ; Xiaolei Gao:1.Department of Obstetrics and Gynecology, Affiliated Hospital of Beihua University, Jilin City, China. ; Lili Liu:1.Department of Obstetrics and Gynecology, Affiliated Hospital of Beihua University, Jilin City, China. ; Yan Jiang:1.Department of Obstetrics and Gynecology, Affiliated Hospital of Beihua University, Jilin City, China. ; Wanting Wen:1.Department of Obstetrics and Gynecology, Affi
期刊：LncRNA Opa interacting protein 5-antisense RNA 1 (OIP5-AS1) promotes the migration, invasion and epithelial-mesenchymal transition (EMT) through targeting miR-147a/insulin-like growth factor 1 receptor (IGF1R) pathway in cervical cancer tissues and c
影响因子 ：1.6
-
Human bone marrow mesenchymal stem cell-derived extracellular vesicles impede the progression of cervical cancer via the miR-144-3p/CEP55 pathway (2006-01-20)
作者：Qin Meng:1.Department of Obstetrics and Gynecology, Shandong Medical College, Linyi, P. R. China. ; Baofang Zhang:1.Department of Physical Examination, The Third People's Hospital of Linyi, Linyi, P. R. China. ; Yingming Zhang:1.Department of Obstetrics and Gynecology, Linyi People's Hospital, Linyi, P. R. China. ; Shuyan Wang:1.Department of Obstetrics and Gynecology, Linyi People's Hospital, Linyi, P. R. China. ; Xiaohui Zhu:1.Department of Obstetrics and Gynecology, Linyi People's Hospital, Linyi, P. R. China. ;
期刊：Human bone marrow mesenchymal stem cell-derived extracellular vesicles impede the progression of cervical cancer via the miR-144-3p/CEP55 pathway
影响因子 ：5.3
-
USP21 regulates Hippo signaling to promote radioresistance by deubiquitinating FOXM1 in cervical cancer (2011-01-20)
作者：Zhengliang Li:1.Department of Radiotherapy, Yantaishan Hospital, No. 10087 Science and Technology Avenue, Laishan District, Yantai, Shandong, China. ; Xiaojing Liu:1.Department of Traditional Chinese Medicine, Yantai Center for Food and Drug Control, Yantai, Shandong, China. ; Haizhou Yu:1.Department of Pharmacology and Toxicology, Yantai Center for Food and Drug Control, Yantai, Shandong, China. ; Shaoping Wang:1.School of Pharmacy, Binzhou Medical University, Yantai, Shandong, China. ; Shuliang Zhao:1.Department of Radiotherapy, Yantaishan Hospital, No. 10087 Science and Technology Avenue, Laishan District, Yantai, Shandong, China. ; Guoxiang Jiang:1.Department of Radiotherapy, Yantaishan Hospital, No. 10087 Science and Technology Avenue, Laishan District, Yantai, Shandong, China. xiangdane8384@126.com. ;
期刊：USP21 regulates Hippo signaling to promote radioresistance by deubiquitinating FOXM1 in cervical cancer
DOI：10.1007/s13577-021-00650-9
影响因子 ：4.3
FAQs
Q：{{item.question}}
A：
产品资料
识别码示意图
