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| 名称 | RT4 (人膀胱移行细胞乳头瘤细胞) (STR鉴定正确) |
| 别称 | RT4; RT4P |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 年龄（性别） | 男性；63岁 |
| 组织来源 | 器官：膀胱；疾病：移行细胞乳头瘤 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 膀胱癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~38-80 hours |
| 致瘤性 | Yes, in cheek pouch of steroid-treated hamsters. |
| 抗原表达情况 | HLA A25(10), A3, B12, Cw3; Blood Type O |
| 保藏机构 | ATCC; HTB-2 DSMZ; ACC-412 ECACC; 91091914 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,12 D2S1338 18,19 D3S1358 15 D5S818 11,12 D7S820 9,12 D8S1179 13,15 D13S317 8 D16S539 9 D18S51 15,17 D19S433 13 D21S11 30,32.2 FGA 22,24 PentaD 12,13 PentaE 7,10 TH01 9,9.3 TPOX 8,11 vWA 14,17 D6S1043 13,19 D12S391 20,22 D2S441 10,13 -
STR鉴定图
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参考文献
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Ubiquitin-specific protease 5 promotes bladder cancer progression through stabilizing Twist1 (2024-01-13)
作者：Hai Cai:1.Department of Urology, Urology Research Institute, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China. ; 2.Department of Urology, National Region Medical center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China. ; Zhi-Bin Ke:1.Department of Urology, Urology Research Institute, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China. ; 2.Department of Urology, National Region Medical center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China. ; Jia-Yin Chen:1.Department of Urology, Urology Research Institute, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China. ; 2.Department of Urology, National Region Medical center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China. ; Xiao-Dong Li:1.Department of Urology, Urology Research Institute, the First Affiliated
期刊：Ubiquitin-specific protease 5 promotes bladder cancer progression through stabilizing Twist1
DOI：10.1038/s41388-023-02936-8
影响因子 ：8.0
引用产品： RT4 细胞
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CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis (2024-01-01)
作者：Peng Zhang:1.Guizhou Medical University, Guiyang, China. ; 2.Department of Urology, Guizhou Provincial People's Hospital, Guiyang, China. ; Qian Yang:1.Department of Gastroenterology, Guizhou Provincial People's Hospital, Guiyang, China. ; Xulong Chen:1.Guizhou Medical University, Guiyang, China. ; Xiaolong Chen:1.Department of Urology, Guizhou Provincial People's Hospital, Guiyang, China. ; Qing Wang:1.Department of Urology, Guizhou Provincial People's Hospital, Guiyang, China. ; Kun Chen:1.Department of Medical Genetics, Guizhou Provincial People's Hospital, Guiyang, China. ; Yu An:1.NHC Key Laboratory of Pulmonary Immune-Related Diseases, Guizhou Provincial People's Hospital, Guiyang, China. ; Kehua Jiang:1.Department of Urology, Guizhou Provincial People's Hospital, Guiyang, China. ; Fa Sun:1.Guizhou Medical University, Guiyang, China. ; 2.Department of Urology, Guizhou Provincial People's Hospital, Guiyang, China. ;
期刊：CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis
影响因子 ：3.9
引用产品： 5637 细胞 , T24 [T-24] 细胞 , RT4 细胞 , J82 细胞 , UM-UC-3 细胞 , SV-HUC-1 细胞
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Validation of hyperthermia as an enhancer of chemotherapeutic efficacy: insights from a bladder cancer organoid model (2024-02-12)
作者：Ying Xu:1.Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China. ; Guoliang Sun:1.Department of Urology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, China. ; Tiantian Yang:1.College of Pharmacy, Hubei University of Science and Technology, Hubei, China. ; Huaibiao Li:1.Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China. ; Poyi Hu:1.Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China. ; Wanru Luo:1.College of Pharmacy, Hubei University of Science and Technology, Hubei, China. ; Tingke Zhang:1.Wuhan Britain-China School, Hubei, China. ; Haoran Liu:1.Bio-X, Stanford University School of Medicine, Stanford, CA, USA. ; Guoyi Chen:1.Department of Urology, Jianyang First Hospital, Fujian, China. ; Zhangqun Ye:1.Department of Urology,
期刊：Validation of hyperthermia as an enhancer of chemotherapeutic efficacy: insights from a bladder cancer organoid model
DOI：10.1080/02656736.2024.2316085
影响因子 ：3.1
引用产品： RT4 细胞 , RT4细胞专用培养基
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The mechanism of PFK-1 in the occurrence and development of bladder cancer by regulating ZEB1 lactylation (2024-03-13)
作者：Rong Wang:1.Department of Urology, Hangzhou Linping TCM Hospital, No.101 Yuncheng Street, Tangxi Town, Linping District, Hangzhou City, 311106, China. drwangr@163.com. ; Fei Xu:1.Department of Urology, Hangzhou Linping TCM Hospital, No.101 Yuncheng Street, Tangxi Town, Linping District, Hangzhou City, 311106, China. ; Zhengjia Yang:1.Department of Urology, Hangzhou Linping TCM Hospital, No.101 Yuncheng Street, Tangxi Town, Linping District, Hangzhou City, 311106, China. ; Jian Cao:1.Department of Urology, Hangzhou Linping TCM Hospital, No.101 Yuncheng Street, Tangxi Town, Linping District, Hangzhou City, 311106, China. ; Liqi Hu:1.Department of Urology, Hangzhou Linping TCM Hospital, No.101 Yuncheng Street, Tangxi Town, Linping District, Hangzhou City, 311106, China. ; Yangyang She:1.Department of Urology, Hangzhou Linping TCM Hospital, No.101 Yuncheng Street, Tangxi Town, Linping District, Hangzhou City, 311106, China. ;
期刊：The mechanism of PFK-1 in the occurrence and development of bladder cancer by regulating ZEB1 lactylation
DOI：10.1186/s12894-024-01444-5
影响因子 ：2.0
引用产品： SV-HUC-1 细胞 , UM-UC-1 细胞 , UM-UC-3 细胞 , RT4 细胞 , RT-112 细胞 , T24 [T-24] 细胞
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POLR3G promotes EMT via PI3K/AKT signaling pathway in bladder cancer (2023-11-07)
作者：Hualin Chen:1.Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ; Lin Ma:1.Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ; Wenjie Yang:1.Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ; Yingjie Li:1.Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ; Zhigang Ji:1.Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ;
期刊：POLR3G promotes EMT via PI3K/AKT signaling pathway in bladder cancer
影响因子 ：4.8
引用产品： T24 [T-24] 细胞 , 5637 细胞 , RT4 细胞 , J82 细胞 , SV-HUC-1 细胞
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The oncogenic role of TFAP2A in bladder urothelial carcinoma via a novel long noncoding RNA TPRG1-AS1/DNMT3A/CRTAC1 axis (2022-11-21)
作者：Jiani He:1.Department of Surgical Oncology and Breast Surgery, The First Hospital of China Medical University, Shenyang 110001, Liaoning, PR China. ; Changming Dong:1.Department of Urology, The First Hospital of China Medical University, Shenyang 110001, Liaoning, PR China; Institute of Urology, China Medical University, Shenyang 110001, Liaoning, PR China. ; Hao Zhang:1.Department of Urology, The First Hospital of China Medical University, Shenyang 110001, Liaoning, PR China; Institute of Urology, China Medical University, Shenyang 110001, Liaoning, PR China. ; Yuanjun Jiang:1.Department of Urology, The First Hospital of China Medical University, Shenyang 110001, Liaoning, PR China; Institute of Urology, China Medical University, Shenyang 110001, Liaoning, PR China. ; Tao Liu:1.Department of Urology, The First Hospital of China Medical University, Shenyang 110001, Liaoning, PR China; Institute of Urology, China Medical University, Shenyang 110001, Liaoning, PR China. ; Xiaojun Ma
期刊：The oncogenic role of TFAP2A in bladder urothelial carcinoma via a novel long noncoding RNA TPRG1-AS1/DNMT3A/CRTAC1 axis
DOI：10.1016/j.cellsig.2022.110527
影响因子 ：4.9
引用产品： RT4 细胞 , T24 [T-24] 细胞 , J82 细胞 , 5637 细胞 , SV-HUC-1 细胞 , 人脐静脉内皮细胞 , 293T [HEK-293T] 细胞
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Long-Lasting Proteinaceous Nanoformulation for Tumor Imaging and Therapy (2022-08-24)
作者：Lai Zhao:1.Department of Urology, China-Japan Union Hospital of Jilin University, Changchun 130033, China. ; 2.State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. ; Xinquan Gu:1.Department of Urology, China-Japan Union Hospital of Jilin University, Changchun 130033, China. ; Fuquan Jiang:1.Department of Urology, China-Japan Union Hospital of Jilin University, Changchun 130033, China. ; Bo Li:1.State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. ; 2.Department of Chemistry, Tsinghua University, Beijing 100084, China. ; Shuang Lu:1.State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. ; Fan Wang:1.State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Che
期刊：Long-Lasting Proteinaceous Nanoformulation for Tumor Imaging and Therapy
影响因子 ：4.1
引用产品： RT4 细胞 , McCoy's 5A 培养基
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Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway (2010-00-20)
作者：Junjiang Liu:1.Department of Urology, Hebei General Hospital, Shijiazhuang, Hebei, P.R. China. ; Yunxia Zhang:1.Department of Obstetrics and Gynecology, Hebei General Hospital, Shijiazhuang, Hebei, P.R. China. ; Chunhong Yu:1.Physical Examination Center, Hebei General Hospital, Shijiazhuang, Hebei, P.R. China. ; Panying Zhang:1.Department of Urology, Hebei General Hospital, Shijiazhuang, Hebei, P.R. China. ; Shouyi Gu:1.Department of Urology, Hebei General Hospital, Shijiazhuang, Hebei, P.R. China. ; Gang Wang:1.Department of Urology, Hebei General Hospital, Shijiazhuang, Hebei, P.R. China. ; Helong Xiao:1.Department of Urology, Hebei General Hospital, Shijiazhuang, Hebei, P.R. China. ; Shoubin Li:1.Department of Urology, Hebei General Hospital, Shijiazhuang, Hebei, P.R. China. ;
期刊：Bergenin inhibits bladder cancer progression via activating the PPARγ/PTEN/Akt signal pathway
影响因子 ：3.8
引用产品： RT4 细胞 , RT4细胞专用培养基 , TCCSUP 细胞 , TCCSUP细胞专用培养基
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β‑elemene enhances cisplatin‑induced apoptosis in bladder cancer cells through the ROS‑AMPK signaling pathway (2011-09-20)
作者：Daoju Gan:1.Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China. ; 2.Central Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China. ; Weiyang He:1.Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China. ; Hubin Yin:1.Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China. ; 2.Chongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China. ; Xin Gou:1.Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China. ;
期刊：β‑elemene enhances cisplatin‑induced apoptosis in bladder cancer cells through the ROS‑AMPK signaling pathway
影响因子 ：2.9
引用产品： RT4 细胞
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Loss of DUSP2 predicts a poor prognosis in patients with bladder cancer (2011-08-20)
作者：Hubin Yin:1.Department of Urology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China; Chongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. ; Weiyang He:1.Department of Urology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. ; Yunhai Li:1.Chongqing Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. ; Ning Xu:1.Departments of Urology, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China. ; Xin Zhu:1.Department of Urology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. ; Yong Lin:1.Molecular Biology and Lung Cancer Program, Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA. ; Xin Gou:1.Department of Urology, the First Affiliated Hospital
期刊：Loss of DUSP2 predicts a poor prognosis in patients with bladder cancer
DOI：10.1016/j.humpath.2018.11.007
影响因子 ：3.3
引用产品： RT4 细胞
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