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产品概述
名称 | SV-HUC-1 (人输尿管上皮永生化细胞) (STR鉴定正确) |
别称 | HUC-1; SV-HUC; SVHUC |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
注意事项 | 该细胞较难消化,注意延长消化时间,消化到细胞收缩变圆,轻拍培养瓶侧边,细胞可以滑落方可终止消化。 |
背景描述 | SV-HUC-1细胞是正常输尿管组织用SV40病毒转染建株的。反复用非洲绿猴肾细胞平板测试检测传染性SV40的生成,结果都呈阴性;SV-HUC-1细胞在胁迫(如曝露于化学试剂)下可能激活病毒。 |
年龄(性别) | 男性;11岁 |
组织来源 | 输尿管,输尿管上皮 |
细胞类型 | 转化细胞系 |
生物安全等级 | BSL-2 |
致瘤性 | No, nude mice. |
基因表达情况 | uroepithelial keratins; SV40 T antigen |
保藏机构 | ATCC; CRL-9520 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,11 D2S1338 17 D3S1358 14,17 D5S818 12,14 D7S820 10,11 D8S1179 14,16 D13S317 12,13 D16S539 11 D18S51 15,16 D19S433 14 D21S11 29,30 FGA 21,22 PentaD 13 PentaE 10,20 TH01 9,9.3 TPOX 8,10 vWA 14 D6S1043 11,13 D12S391 18 D2S441 10,13 -
STR鉴定图
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参考文献
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Methyltransferase-like 7B participates in bladder cancer via ACSL3 m6A modification in a ferroptosis manner (2025-01-20)
期刊:Biology Direct
DOI:10.1186/s13062-025-00597-z
影响因子 :5.7
引用产品: SV-HUC-1 细胞 , McCoy's 5A 培养基
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Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning (2025-01-23)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2025.1511529
影响因子 :5.7
引用产品: SV-HUC-1 细胞
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S100A8 promotes the proliferation, migration and invasion in bladder cancer cells (2025-01-01)
期刊:Journal of Cancer
影响因子 :3.3
引用产品: SV-HUC-1 细胞 , Ham's F-12 培养基
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Exploring the therapeutic potential of PACAP in Hunner-type Interstitial Cystitis (2025-01-04)
期刊:WORLD JOURNAL OF UROLOGY
DOI:10.1007/s00345-024-05429-9
影响因子 :2.8
引用产品: SV-HUC-1 细胞
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Programmable Microfluidic-Assisted Highly Conductive Hydrogel Patches for Customizable Soft Electronics (2024-07-09)
期刊:ADVANCED FUNCTIONAL MATERIALS
影响因子 :18.5
引用产品: SV-HUC-1 细胞
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Subcellular Nanobionic Liposome with High Zeta Potential Enhances Intravesical Adhesion and Drug Delivery (2024-01-22)
期刊:ACS Nano
影响因子 :17.1
引用产品: SV-HUC-1 细胞 , RAW 264.7 细胞
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Harnessing Natural Pollen as Sustained-Release, Mucoadhesive, and Biosafe Drug Microcapsules for Intravesical Instillation in Bladder Cancer Treatment (2024-12-09)
期刊:Small
影响因子 :13.0
引用产品: T24 [T-24] 细胞 , MB49 细胞 , SV-HUC-1 细胞
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Mechanistic insights into SIRT7 and EZH2 regulation of cisplatin resistance in bladder cancer cells (2024-12-24)
期刊:Cell Death & Disease
DOI:10.1038/s41419-024-07321-1
影响因子 :8.1
引用产品: SV-HUC-1 细胞 , T24 [T-24] 细胞 , UM-UC-3 细胞 , J82 细胞 , TCCSUP 细胞 , SW 780 [SW-780, SW780] 细胞 , RT-112 细胞 , 特级胎牛血清 , 青霉素-链霉素溶液(双抗),100× , Ham's F-12K 培养基 , McCoy's 5A 培养基 , MEM(含NEAA) 培养基 , Leibovitz's L-15 培养基 , RPMI-1640 培养基
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Nuclear translocation of ISG15 regulated by PPP2R2B inhibits cisplatin resistance of bladder cancer (2024-07-08)
期刊:CELLULAR AND MOLECULAR LIFE SCIENCES
DOI:10.1007/s00018-024-05320-1
影响因子 :6.2
引用产品: J82 细胞 , 5637 细胞 , T24 [T-24] 细胞 , UM-UC-3 细胞 , SV-HUC-1 细胞
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RNF19A inhibits bladder cancer progression by regulating ILK ubiquitination and inactivating the AKT/mTOR signalling pathway (2024-11-06)
期刊:Biology Direct
DOI:10.1186/s13062-024-00562-2
影响因子 :5.7
引用产品: SV-HUC-1 细胞
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ARNTL2 facilitates bladder cancer progression through potentiating ENO1-mediated glycolysis in a SLC31A1-independent and -dependent manner (2024-08-13)
期刊:LIFE SCIENCES
影响因子 :5.2
引用产品: HT-1376 细胞 , SV-HUC-1 细胞 , 5637 细胞 , 青霉素-链霉素溶液(双抗),100× , MEM(含NEAA) 培养基
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Preparation and characterization of PLGA nano-drug delivery system co-loaded with tranilast/gallium phytate for stent coating (2024-05-23)
期刊:JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI:10.1016/j.jddst.2024.105812
影响因子 :5.0
引用产品: SV-HUC-1 细胞
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Transcriptomic profiling and risk assessment in bladder cancer: Insights from copper death-related genes (2024-05-27)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2024.111237
影响因子 :4.8
引用产品: T24 [T-24] 细胞 , SV-HUC-1 细胞 , J82 细胞 , 5637 细胞 , 293T [HEK-293T] 细胞
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A novel anoikis-related gene signature identifies LYPD1 as a novel therapy target for bladder cancer (2024-02-08)
期刊:Scientific Reports
DOI:10.1038/s41598-024-53272-0
影响因子 :4.6
引用产品: 5637 细胞 , T24 [T-24] 细胞 , UM-UC-3 细胞 , SV-HUC-1 细胞
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Identification and preliminary analysis of hub genes associated with bladder cancer progression by comprehensive bioinformatics analysis (2024-02-02)
期刊:Scientific Reports
DOI:10.1038/s41598-024-53265-z
影响因子 :4.6
引用产品: SV-HUC-1 细胞 , 5637 细胞 , T24 [T-24] 细胞 , UM-UC-3 细胞 , SW 780 [SW-780, SW780] 细胞
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Integrated analysis of bulk and single-cell RNA-seq data reveals cell differentiation-related subtypes and a scoring system in bladder cancer (2024-10-14)
期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 :4.3
引用产品: T24 [T-24] 细胞 , SV-HUC-1 细胞 , 5637 细胞 , UM-UC-3 细胞 , J82 细胞
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BHLHE41 inhibits bladder cancer progression via regulation of PYCR1 stability and thus inactivating PI3K/AKT signaling pathway (2024-05-29)
期刊:EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI:10.1186/s40001-024-01889-2
影响因子 :4.2
引用产品: SV-HUC-1 细胞
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Activation of Piezo1 channels enhances spontaneous contractions of isolated human bladder strips via acetylcholine release from the mucosa (2024-09-03)
期刊:EUROPEAN JOURNAL OF PHARMACOLOGY
DOI:10.1016/j.ejphar.2024.176954
影响因子 :4.2
引用产品: SV-HUC-1 细胞
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CENPW knockdown inhibits progression of bladder cancer through inducing cell cycle arrest and apoptosis (2024-01-01)
期刊:Journal of Cancer
影响因子 :3.9
引用产品: 5637 细胞 , T24 [T-24] 细胞 , RT4 细胞 , J82 细胞 , UM-UC-3 细胞 , SV-HUC-1 细胞
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Revealing the mechanisms of RAC3 in tumor aggressiveness, the immunotherapy response, and drug resistance in bladder cancer (2024-09-16)
期刊:Frontiers in Oncology
影响因子 :3.5
引用产品: 5637 细胞 , T24 [T-24] 细胞 , SV-HUC-1 细胞
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PC4 promotes bladder cancer progression and stemness by directly interacting with Sp1 to transcriptionally activate the Wnt5a/β-catenin pathway (2024-05-26)
期刊:PATHOLOGY RESEARCH AND PRACTICE
影响因子 :2.8
引用产品: UM-UC-3 细胞 , J82 细胞 , SV-HUC-1 细胞 , T24 [T-24] 细胞
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CircRNA ATF6 suppresses bladder cancer cell proliferation and migration via miR-146a-5p/FLNA axis (2024-07-31)
期刊:MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
DOI:10.1016/j.mrfmmm.2024.111876
影响因子 :2.3
引用产品: RT4 细胞 , SV-HUC-1 细胞 , 青霉素-链霉素溶液(双抗),100× , 293T [HEK-293T] 细胞 , MEM(含NEAA) 培养基 , DMEM高糖 培养基 , J82 细胞 , Ham's F-12K 培养基 , T24 [T-24] 细胞 , McCoy's 5A 培养基 , 5637 细胞 , RPMI-1640 培养基 , 特级胎牛血清
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The mechanism of PFK-1 in the occurrence and development of bladder cancer by regulating ZEB1 lactylation (2024-03-13)
期刊:BMC Urology
DOI:10.1186/s12894-024-01444-5
影响因子 :2.0
引用产品: SV-HUC-1 细胞 , UM-UC-1 细胞 , UM-UC-3 细胞 , RT4 细胞 , RT-112 细胞 , T24 [T-24] 细胞
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Methyltransferase like 13 promotes malignant behaviors of bladder cancer cells through targeting PI3K/ATK signaling pathway (2024-12-18)
期刊:Open Life Sciences
影响因子 :1.7
引用产品: SV-HUC-1 细胞 , J82 细胞 , T24 [T-24] 细胞
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m6A reader IGF2BP2 promotes M2 macrophage polarization and malignant biological behavior of bladder cancer by stabilizing NRP1 mRNA expression (2024-07-16)
期刊:BMC Urology
DOI:10.1186/s12894-024-01534-4
影响因子 :1.7
引用产品: THP-1 细胞 , SV-HUC-1 细胞 , T24 [T-24] 细胞 , 青霉素-链霉素溶液(双抗),100× , 5637 细胞
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STAT1 as a potential therapeutic target to treat bladder cancer (2024-09-15)
期刊:International Journal of Clinical and Experimental Pathology
影响因子 :1.1
引用产品: SV-HUC-1 细胞 , 5637 细胞 , T24 [T-24] 细胞
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The alternation of halobenzoquinone disinfection byproduct on toxicogenomics of DNA damage and repair in uroepithelial cells (2023-12-22)
期刊:ENVIRONMENT INTERNATIONAL
DOI:10.1016/j.envint.2023.108407
影响因子 :11.8
引用产品: SV-HUC-1 细胞 , Ham's F-12 培养基
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WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity (2023-01-07)
期刊:CANCER LETTERS
DOI:10.1016/j.canlet.2023.216058
影响因子 :9.7
引用产品: SV-HUC-1 细胞 , UM-UC-3 细胞 , J82 细胞 , 5637 细胞 , SW 780 [SW-780, SW780] 细胞 , T24 [T-24] 细胞 , TCCSUP 细胞 , Ham's F-12K 培养基 , MEM (含NEAA) 培养基 , Leibovitz's L-15 培养基 , McCoy's 5A 培养基
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Pan-cancer analysis of PLAU indicates its potential prognostic value and correlation with neutrophil infiltration in BLCA (2023-11-22)
期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI:10.1016/j.bbadis.2023.166965
影响因子 :6.2
引用产品: MCF7 [MCF-7] 细胞 , Caco-2 细胞 , SW480 [SW-480] 细胞 , CAL 27 细胞 , KHM-5M 细胞 , SV-HUC-1 细胞 , 5637 细胞 , UM-UC-3 细胞 , EJ-1 细胞 , T24 [T-24] 细胞 , TCCSUP 细胞
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circCD2AP promotes epithelial mesenchymal transition and stemness in bladder cancer by regulating FOXQ1/USP21 axis (2023-11-14)
期刊:iScience
DOI:10.1016/j.isci.2023.108447
影响因子 :5.8
引用产品: SV-HUC-1 细胞
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An innovative model based on N7-methylguanosine-related lncRNAs for forecasting prognosis and tumor immune landscape in bladder cancer (2023-05-08)
期刊:Cancer Cell International
DOI:10.1186/s12935-023-02933-7
影响因子 :5.8
引用产品: T24 [T-24] 细胞 , UM-UC-3 细胞 , SV-HUC-1 细胞
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Inhibition of the NF-κB Signaling Pathway Alleviates Pyroptosis in Bladder Epithelial Cells and Neurogenic Bladder Fibrosis (2023-07-06)
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :5.6
引用产品: SV-HUC-1 细胞
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Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells (2023-01-17)
期刊:Frontiers in Chemistry
DOI:10.3389/fchem.2023.1121724
影响因子 :5.5
引用产品: T24 [T-24] 细胞 , SV-HUC-1 细胞 , RPMI-1640 培养基 , MEM (含NEAA) 培养基 , 青霉素-链霉素溶液 (双抗),100×
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Immunogenic Cell Death Associated Molecular Patterns and the Dual Role of IL17RA in Interstitial Cystitis/Bladder Pain Syndrome (2023-02-23)
期刊:Biomolecules
影响因子 :5.5
引用产品: SV-HUC-1 细胞 , RAW 264.7 细胞
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Unveiling clinical significance and tumor immune landscape of CXCL12 in bladder cancer: Insights from multiple omics analysis (2023-12-12)
期刊:Chinese Journal of Cancer Research
DOI:10.21147/j.issn.1000-9604.2023.06.12
影响因子 :5.1
引用产品: UM-UC-3 细胞 , T24 [T-24] 细胞 , SV-HUC-1 细胞
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POLR3G promotes EMT via PI3K/AKT signaling pathway in bladder cancer (2023-11-07)
期刊:FASEB JOURNAL
影响因子 :4.8
引用产品: T24 [T-24] 细胞 , 5637 细胞 , RT4 细胞 , J82 细胞 , SV-HUC-1 细胞
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Label-free LC-MS/MS proteomics analyses reveal CLIC1 as a predictive biomarker for bladder cancer staging and prognosis (2023-01-16)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞 , J82 细胞 , RT-112 细胞 , EJ-1 细胞 , TCCSUP 细胞 , UM-UC-3 细胞
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A pan-cancer analysis of DDR1 in prognostic signature and tumor immunity, drug resistance (2023-04-08)
期刊:Scientific Reports
DOI:10.1038/s41598-023-27975-9
影响因子 :4.6
引用产品: HK-2 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞 , SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞 , RWPE-1 细胞 , PC-3 细胞 , DU 145 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , Ham's F-12K 培养基 , 人前列腺上皮细胞完全培养基
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HEATR3 involved in the cell proliferation, metastasis and cell cycle development of bladder cancer acts as a tumor suppressor (2023-07-31)
期刊:MOLECULAR GENETICS AND GENOMICS
DOI:10.1007/s00438-023-02046-w
影响因子 :3.1
引用产品: 5637 细胞 , SW 780 [SW-780, SW780] 细胞 , TCCSUP 细胞 , SV-HUC-1 细胞
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Ligustilide induces apoptosis and reduces proliferation in human bladder cancer cells by NFκB1 and mitochondria pathway (2023-02-08)
期刊:Chemical Biology & Drug Design
影响因子 :3.0
引用产品: T24 [T-24] 细胞 , EJ-1 细胞 , SV-HUC-1 细胞
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Hsa_circ_0008035 Knockdown Inhibits Bladder Cancer Progression through miR-1184/RAP2B Axis (2023-06-13)
期刊:UROLOGIA INTERNATIONALIS
影响因子 :1.6
引用产品: SV-HUC-1 细胞 , 5637 细胞 , T24 [T-24] 细胞 , 人脐静脉内皮细胞
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A modified biodegradable mesh ureteral stent for treating ureteral stricture disease (2022-11-17)
期刊:Acta Biomaterialia
DOI:10.1016/j.actbio.2022.11.022
影响因子 :10.6
引用产品: SV-HUC-1 细胞 , SV-HUC-1细胞专用培养基
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Hypoxia-Induced HIF-1α Expression Promotes Neurogenic Bladder Fibrosis via EMT and Pyroptosis (2022-11-29)
期刊:Cells
影响因子 :7.7
引用产品: SV-HUC-1 细胞
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Ferroptosis-Related Long Noncoding RNAs Have Excellent Predictive Ability for Multiomic Characteristics of Bladder Cancer (2022-08-29)
期刊:Oxidative Medicine and Cellular Longevity
影响因子 :7.3
引用产品: SV-HUC-1 细胞 , BIU-87 细胞 , HT-1376 细胞 , T24 [T-24] 细胞 , RT4 细胞 , RT-112 细胞 , 5637 细胞 , UM-UC-3 细胞
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Ferroptosis Mediation Patterns Reveal Novel Tool to Implicate Immunotherapy and Multi-Omics Characteristics in Bladder Cancer (2022-01-25)
期刊:Frontiers in Cell and Developmental Biology
影响因子 :6.1
引用产品: SV-HUC-1 细胞 , HT-1376 细胞 , BIU-87 细胞 , T24 [T-24] 细胞 , RT4 细胞 , 5637 细胞
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Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis. (2022-09-21)
期刊:Frontiers in Pharmacology
影响因子 :6.0
引用产品: SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞 , HK-2 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞 , RWPE-1 细胞 , PC-3 细胞 , DU 145 细胞 , Ham's F-12K 培养基 , DMEM高糖 培养基 , 人前列腺上皮细胞完全培养基 , RPMI-1640 培养基
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Identification of immuno-infiltrating MAP1A as a prognosis-related biomarker for bladder cancer and its ceRNA network construction (2022-11-02)
期刊:Frontiers in Oncology
影响因子 :5.7
引用产品: 5637 细胞 , SW 780 [SW-780, SW780] 细胞 , SV-HUC-1 细胞
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The oncogenic role of TFAP2A in bladder urothelial carcinoma via a novel long noncoding RNA TPRG1-AS1/DNMT3A/CRTAC1 axis (2022-11-21)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2022.110527
影响因子 :4.9
引用产品: RT4 细胞 , T24 [T-24] 细胞 , J82 细胞 , 5637 细胞 , SV-HUC-1 细胞 , 人脐静脉内皮细胞 , 293T [HEK-293T] 细胞
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Immunogenic cell death mediation patterns reveal novel paradigm for characterizing the immune microenvironment and immunotherapeutic responses in bladder cancer. (2022-10-25)
期刊:Frontiers in Genetics
DOI:10.3389/fgene.2022.1035484
影响因子 :4.8
引用产品: SV-HUC-1 细胞 , T24 [T-24] 细胞
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NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway (2022-01-02)
期刊:Cell Cycle
DOI:10.1080/15384101.2021.2021050
影响因子 :4.3
引用产品: SV-HUC-1 细胞 , UM-UC-3 细胞 , 5637 细胞 , SW 780 [SW-780, SW780] 细胞
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circCEP128 Knockdown Suppresses Bladder Cancer Progression via Regulating microRNA-515-5p/SDC1 Axis (2022-12-21)
期刊:Cancer Management and Research
影响因子 :3.6
引用产品: RPMI-1640 培养基 , T24 [T-24] 细胞 , SV-HUC-1 细胞 , 5637 细胞 , 青霉素-链霉素溶液(双抗),100×
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Long Noncoding RNA HAND2-AS1 Suppresses Cell Proliferation, Migration, and Invasion of Bladder Cancer via miR-17-5p/KLF9 Axis (2022-01-10)
期刊:DNA and Cell Biology
影响因子 :3.1
引用产品: T24 [T-24] 细胞 , 5637 细胞 , UM-UC-3 细胞 , SW 780 [SW-780, SW780] 细胞 , TCCSUP 细胞 , SV-HUC-1 细胞
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A novel signature constructed by ferroptosis-associated genes (FAGs) for the prediction of prognosis in bladder urothelial carcinoma (BLCA) and associated with immune infiltration (2021-08-06)
期刊:Cancer Cell International
DOI:10.1186/s12935-021-02096-3
影响因子 :5.8
引用产品: SV-HUC-1 细胞
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circ_100984‐miR‐432‐3p axis regulated c‐Jun/YBX‐1/β‐catenin feedback loop promotes bladder cancer progression (2021-02-10)
期刊:Cancer Science
影响因子 :5.7
引用产品: SV-HUC-1 细胞
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CRTAC1 (Cartilage acidic protein 1) inhibits cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) process in bladder cancer by downregulating Yin Yang 1 (YY1) to inactivate the TGF-β pathway (2021-11-24)
期刊:Bioengineered
DOI:10.1080/21655979.2021.1974645
影响因子 :4.9
引用产品: SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞
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RETRACTED: Baicalein inhibits proliferation and migration of bladder cancer cell line T24 by down-regulation of microRNA-106 (2018-11-01)
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2018.08.107
影响因子 :7.5
引用产品: SV-HUC-1 细胞
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