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产品概述
产品简介
白细胞介素-2 （IL-2）是一种α螺旋状细胞因子，它的分子量为15kDa，是具有强大的免疫调节的淋巴因子，由 T 细胞响应抗原性或促有丝分裂刺激而产生。该淋巴因子可促进活化T细胞和相关细胞类型的长期生长。IL-2在NK细胞的激活和增殖中发挥作用、诱导γ-干扰素和B细胞生长因子的分泌，并调节IL-2受体的表达。此产品专用于NK-92完全培养基（CM-0530）。
产品信息
形态 | 液体 |
规格 | 250uLⅹ4 |
溶剂 | 0.9%生理盐水 |
浓度 | 1ⅹ105U/mL |
储存条件 | -5~-20℃，避光 |
运输条件 | 低温 |
有效期 | 3个月 |
产品使用方法
1、白介素 2（IL-2）溶解后进行短暂离心，将附着在盖子上的液体离下来。
2、按照 1:500 的比例，将 250ul 的白介素 2（IL-2）添加到 125ml 的 NK-92 细胞专用培养基中，配制成完全培养基。
3、配好的完全培养基放入2-8℃冰箱避光保存，一周内用完。
注意事项
1、本产品经0.22μm过滤除菌。
2、使用本产品时应注意无菌操作，避免污染。
3、白介素 2（IL-2）在−5~-20 °C下稳定，避免反复冻融。
4、白介素 2（IL-2）易降解，配好的完全培养基，应在一周内用完。
5、本产品仅用于科研或进一步研究使用，不用于诊断和治疗。
参考文献
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NK92 cells and peripheral blood NK cells respond oppositely upon dasatinib treatment (2024-02-15)
作者：Fengqi Li:1.School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China. ; 2.Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, Tianjin University, Tianjin, China. ; Zhongyi Wang:1.School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China. ; 2.Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, Tianjin University, Tianjin, China. ; Dongpeng Zheng:1.School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China. ; 2.Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, Tianjin University, Tianjin, China. ; Zhaojun Pang:1.School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China. ; 2.Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug
期刊：NK92 cells and peripheral blood NK cells respond oppositely upon dasatinib treatment
影响因子 ：6.4
引用产品： 青霉素-链霉素溶液 (双抗)，100× , NK-92 细胞 , MEMα (不含核苷) 培养基 , IL-2 (重组人白细胞介素-2、白细胞介素-2) (250μL×4) , 马血清 , 特级胎牛血清
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The immunomodulatory effects of DNA-conjugated collagen scaffolds on bone healing (2023-08-26)
作者：Jing-han Song: 1.State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Centre for Oral Diseases & Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, China; Jun-ting Gu: 1.State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Centre for Oral Diseases & Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, China;2.National Translational Science Center for Molecular Medicine, Department of Cell Biology, State Key Laboratory of Cancer Biology, The Fourth Military Medical University, Xi’an, China; Gao-peng Dang: 1.State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Centre for Oral Diseases & Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School
期刊：The immunomodulatory effects of DNA-conjugated collagen scaffolds on bone healing
影响因子 ：15.1
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Study on the Effect of EZH2 Inhibitor Combined with TIGIT Monoclonal Antibody against Multiple Myeloma Cells (2023-05-11)
作者：Zhaoyun Liu:1.Department of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin 300052, China. ; Yue Jia:1.Department of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin 300052, China. ; Chun Yang:1.Department of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin 300052, China. ; Hui Liu:1.Department of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin 300052, China. ; Hongli Shen:1.Department of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin 300052, China. ; Hao Wang:1.Department of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin 300052, China. ; Rong Fu:1.Department of Hematology, Tianjin Medical University General Hospital, 154 Anshan Street, Heping District, Tianjin 300052
期刊：Study on the Effect of EZH2 Inhibitor Combined with TIGIT Monoclonal Antibody against Multiple Myeloma Cells
影响因子 ：5.6
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Epithelial Galectin-3 Induced the Mitochondrial Complex Inhibition and Cell Cycle Arrest of CD8+ T Cells in Severe/Critical COVID-19 (2023-08-14)
作者：Yudie Wang:1.Department of Biology and Genetics, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan 430065, China. ; Cheng Yang:1.Department of Biology and Genetics, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan 430065, China. ; Zhongyi Wang:1.Department of Biology and Genetics, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan 430065, China. ; Yi Wang:1.Department of Biology and Genetics, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan 430065, China. ; Qing Yan:1.Department of Biology and Genetics, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan 430065, China. ; Ying Feng:1.Department of Biology and Genetics, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan 430065, China. ; Yanping Liu:1.Department of Biology and Genetics, College of Life Sciences and H
期刊：Epithelial Galectin-3 Induced the Mitochondrial Complex Inhibition and Cell Cycle Arrest of CD8+ T Cells in Severe/Critical COVID-19
影响因子 ：5.6
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Circ_0000745 regulates NOTCH1-mediated cell proliferation and apoptosis in pediatric T-cell acute lymphoblastic leukemia through adsorbing miR-193b-3p (2011-01-20)
作者：Huanhuan Feng:1.Department of Neonatology, Xi'an Gaoxi Hospital, Xi'an, People's Republic of China. ; Fei Li:1.Department of Neonatology, Xi'an Gaoxi Hospital, Xi'an, People's Republic of China. ; Ping Tang:1.Department of Neonatology, Xi'an Gaoxi Hospital, Xi'an, People's Republic of China. ;
期刊：Circ_0000745 regulates NOTCH1-mediated cell proliferation and apoptosis in pediatric T-cell acute lymphoblastic leukemia through adsorbing miR-193b-3p
DOI：10.1080/16078454.2021.1997197
影响因子 ：1.9
引用产品： 人外周血单个核细胞 , CCRF-CEM [CCRF CEM] 细胞 , Jurkat, Clone E6-1 细胞 , RPMI-1640 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100× , IL-2 (重组人白细胞介素-2、白细胞介素-2) (250μL×4)
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