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产品概述
| 名称 | SW-13 (人肾上腺皮质小细胞癌细胞) (STR鉴定正确) |
| 种属 | 人类 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，100%, 温度：37℃
|
| 培养方案B（可选） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 1.该细胞推荐使用Leibovitz's L-15培养基进行培养，Leibovitz's L-15不可以通入二氧化碳，会产生细胞毒性；2.如您没有无二氧化碳的培养箱，可使用DMEM替代Leibovitz's L-15，使用DMEM培养基时即可正常通入5%二氧化碳；3.配套专用培养基默认Leibovitz's L-15配置，如需DMEM配方，请联系销售下单备注更改。 |
| 背景描述 | SW-13细胞是于1971年8月从55岁的患有肾上腺皮质癌的白人女性患者中分离建立的。该患者的病理诊断为Ⅳ级肾上腺皮质原发性小细胞癌。电镜显示，SW-13细胞有许多球形缝隙连接(BGJ)。 |
| 年龄（性别） | 女性；55岁 |
| 组织来源 | 器官：肾上腺；组织：皮质；肿瘤阶段：Ⅳ级；疾病：原发性小细胞癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肾癌细胞 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 19,20 D3S1358 16 D5S818 11,12 D7S820 8,10 D8S1179 10 D13S317 9 D16S539 12 D18S51 17 D19S433 14,15 D21S11 31,32.2 FGA 20 PentaD 10,13 PentaE 7,15 TH01 7,8 TPOX 8 vWA 17,19 D6S1043 12,15 D12S391 20,22 D2S441 14 -
STR鉴定图
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参考文献
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N7-methylguanosine regulatory genes well represented by METTL1 define vastly different prognostic, immune and therapy landscapes in adrenocortical carcinoma (2023-02-15)
作者：Fangshi Xu:1.Department of Urology, Second Affiliated Hospital of Xi'an Jiaotong University No. 157, West Five Road, Xi'an 710004, Shaanxi, China. ; 2.Department of Urology, Shaanxi Provincial People's Hospital No. 256, Friendship West Road, Xi'an 710068, Shaanxi, China. ; Danrui Cai:1.Department of Ophthalmology, Second Affiliated Hospital of Xi'an Jiaotong University No. 157, West Five Road, Xi'an 710004, Shaanxi, China. ; Shanshan Liu:1.Department of Rheumatology and Immunology, Second Affiliated Hospital of Xi'an Jiaotong University Xi'an, Shaanxi, China. ; Kaini He:1.Department of Gastroenterology, Second Affiliated Hospital of Xi'an Jiaotong University Xi'an, Shaanxi, China. ; Jing Chen:1.Department of Rheumatology and Immunology, Second Affiliated Hospital of Xi'an Jiaotong University Xi'an, Shaanxi, China. ; Li Qu:1.Department of Rheumatology and Immunology, Second Affiliated Hospital of Xi'an Jiaotong University Xi'an, Shaanxi, China. ; Tie Chong:1.Department of Urology,
期刊：N7-methylguanosine regulatory genes well represented by METTL1 define vastly different prognostic, immune and therapy landscapes in adrenocortical carcinoma
DOI：PMID:36895966
影响因子 ：5.3
引用产品： NCI-H295R 细胞 , SW-13 细胞
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CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis (2022-10-02)
作者：Liwen Ren:1.The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. ; 2.Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. ; Yihui Yang:1.The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. ; 2.Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. ; Wan Li:1.The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. ; 2.Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. ; Xiangjin Zheng:1.The State Key Laboratory of Bioactive Substance and Function of Natural M
期刊：CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
DOI：10.1186/s12967-022-03641-y
影响因子 ：8.4
引用产品： NCI-H295R 细胞 , SW-13 细胞 , SW-13细胞专用培养基 (L15) , NCI-H295R细胞专用培养基
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Identification of Seven Aberrantly Methylated and Expressed Genes in Adrenocortical Carcinoma (2007-09-20)
作者：He Xiao:1.Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. ; Weixiang He:1.Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. ; Ping Chen:1.Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. ; Deqiang Xu:1.Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. ; Guang Zeng:1.Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. ; Zhuo Li:1.Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. ; 2.Department of Urology, Shenzhen Sixth People's Hospital, Shenzhen, China. ; 3.The Sixth Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China. ; 4.Affiliated Shenzhen Sixth Hospital of Guangdong Medical University, Shenzhen, China. ; 5.Shenzhen Key Laboratory for Endogenous Infection, Shenzhen, China. ; Mingliu Huang:1.Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. ; Xinghuan Wang:1.Departme
期刊：Identification of Seven Aberrantly Methylated and Expressed Genes in Adrenocortical Carcinoma
影响因子 ：5.2
引用产品： SW-13 细胞 , NCI-H295R 细胞
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