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产品概述
| 名称 | NRK-52E (大鼠肾细胞) (种属鉴定正确) |
| 别称 | NRK 52E; NRK52E; NRK clone 52E; Normal Rat Kidney-52E; NRK-E52 |
| 种属 | 大鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 组织来源 | 正常肾 |
| 细胞类型 | 自发永生化细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~45 hours |
| 受体表达情况 | epidermal growth factor (EGF); multiplication stimulating activity (MSA) |
| 保藏机构 | ATCC; CRL-1571 DSMZ; ACC-199 ECACC; 87012902 |
种属鉴定
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种属鉴定图
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参考文献
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Butyrolactone I blocks the transition of acute kidney injury to chronic kidney disease in mice by targeting JAK1 (2025-01-21)
期刊：MedComm
影响因子 ：10.7
引用产品： HK-2 细胞 , NRK-52E 细胞
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Calycosin extracted from Astragali Radix reduces NETs formation to improve renal fibrosis via TLR4/NF-κB pathway (2025-01-22)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：4.8
引用产品： NRK-52E 细胞
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Silibinin Attenuates Ferroptosis in Acute Kidney Injury by Targeting FTH1 (2024-09-20)
期刊：Redox Biology
DOI：10.1016/j.redox.2024.103360
影响因子 ：10.7
引用产品： HK-2 细胞 , NRK-52E 细胞 , 小鼠肾小管上皮细胞
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Anti-Cancer Potency of Copper-Doped Carbon Quantum Dots Against Breast Cancer Progression (2024-02-26)
期刊：International Journal of Nanomedicine
影响因子 ：8.0
引用产品： NRK-52E 细胞 , TM3 细胞 , MA-782细胞专用培养基 , TM3细胞专用培养基 , DMEM高糖完全培养基 (含10%FBS）
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Investigation of the molecular mechanisms underlying the anti-inflammatory and antitumour effects of isorhapontigenin: Insights from in vitro and in vivo studies (2024-09-25)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.117479
影响因子 ：6.9
引用产品： NRK-52E 细胞
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Isolation and target identification of anti-renal fibrosis compounds from Cordyceps militaris (2024-02-03)
期刊：BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2024.107169
影响因子 ：5.1
引用产品： NRK-52E 细胞
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Qi-dan-dihuang decoction ameliorates renal fibrosis in diabetic rats via p38MAPK/AKT/mTOR signaling pathway (2024-03-08)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.5
引用产品： HK-2 细胞 , NRK-52E 细胞
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Calcium sensing receptor regulate claudin-14 via PKA-STAT3 pathway in rat model of nephrolithiasis (2024-12-04)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2024.1477122
影响因子 ：4.4
引用产品： NRK-52E 细胞
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LncRNA HMOX1 alleviates renal ischemia-reperfusion-induced ferroptotic injury via the miR-3587/HMOX1 axis (2024-04-06)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2024.111165
影响因子 ：4.4
引用产品： NRK-52E 细胞
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HAO2 protects from proximal tubular cells injured in rats with chronic kidney disease by promoting fatty acid metabolic processes (2024-07-14)
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI：10.1016/j.bbadis.2024.167342
影响因子 ：4.2
引用产品： NRK-52E 细胞
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Usp9x contributes to the development of sepsis-induced acute kidney injury by promoting inflammation and apoptosis in renal tubular epithelial cells via activation of the TLR4/nf-κb pathway (2024-06-14)
期刊：RENAL FAILURE
DOI：10.1080/0886022X.2024.2361089
影响因子 ：3.0
引用产品： NRK-52E 细胞
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Four new guaiane sesquiterpenes from Agarwood of Aquilaria sinensis and their biological activity toward renal fibrosis (2024-07-23)
期刊：FITOTERAPIA
DOI：10.1016/j.fitote.2024.106143
影响因子 ：2.5
引用产品： NRK-52E 细胞
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MiR-125b-1-3p-mediated UQCRB inhibition facilitates mitochondrial metabolism disorders in a rat cellular senescencemodel (2024-08-14)
期刊：MOLECULAR AND CELLULAR PROBES
影响因子 ：2.3
引用产品： DMEM高糖 培养基 , NRK-52E 细胞 , 青霉素-链霉素溶液（双抗），100× , 293T [HEK-293T] 细胞
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Photoactivatable senolysis with single-cell resolution delays aging (2023-02-02)
期刊：Nature Aging
DOI：10.1038/s43587-023-00360-x
影响因子 ：16.6
引用产品： NRK-52E 细胞
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Jiedu Tongluo Baoshen formula enhances renal tubular epithelial cell autophagy to prevent renal fibrosis by activating SIRT1/LKB1/AMPK pathway (2023-02-03)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2023.114340
影响因子 ：7.5
引用产品： NRK-52E 细胞 , HK-2 细胞
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Renoprotective Glycoside Derivatives from Zingiber officinale (Ginger) Peels (2023-10-09)
期刊：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 ：6.1
引用产品： NRK-52E 细胞
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Gasdermin D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway (2023-11-14)
期刊：iScience
DOI：10.1016/j.isci.2023.108463
影响因子 ：5.8
引用产品： NRK-52E 细胞 , HK-2 细胞
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Blocking GSDMD Alleviates Hyperuricemia-Induced Renal Tubular Injury by Inhibiting RIG-I/Caspase-1-Mediated Pyroptosis (2023-03-03)
期刊：iScience
影响因子 ：5.8
引用产品： NRK-52E 细胞
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Renoprotective effects of ferulic acid mediated by AMPKα1 against lipopolysaccharide-induced damage (2023-01-25)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.109703
影响因子 ：5.6
引用产品： NRK-52E 细胞
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Analysis of microRNA expression in rat kidneys after VEGF inhibitor-treatment under different degrees of hypoxia (2023-08-29)
期刊：PHYSIOLOGICAL GENOMICS
DOI：10.1152/physiolgenomics.00023.2023
影响因子 ：4.6
引用产品： NRK-52E 细胞
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Unusual acetylated flavonol glucuronides, oxyphyllvonides A−H with renoprotective activities from the fruits of Alpinae oxyphylla (2023-09-09)
期刊：PHYTOCHEMISTRY
DOI：10.1016/j.phytochem.2023.113849
影响因子 ：3.8
引用产品： NRK-52E 细胞
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Retro-dihydrochalcones from the resin of Daemonorops draco and their inhibitory activities against renal fibrosis (2023-04-23)
期刊：FITOTERAPIA
DOI：10.1016/j.fitote.2023.105515
影响因子 ：3.4
引用产品： NRK-52E 细胞
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Role of Nox4 in high calcium-induced renal oxidative stress damage and crystal deposition (2022-01-17)
期刊：Antioxidants & Redox Signaling
影响因子 ：7.5
引用产品： NRK-52E 细胞
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Protective Effects of PPARγ on Renal Ischemia-Reperfusion Injury by Regulating miR-21 (2022-08-30)
期刊：Oxidative Medicine and Cellular Longevity
影响因子 ：7.3
引用产品： NRK-52E 细胞
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Estradiol Ameliorates Acute Kidney Ischemia-Reperfusion Injury by Inhibiting the TGF-βRI-SMAD Pathway. (2022-02-24)
期刊：Frontiers in Immunology
影响因子 ：7.3
引用产品： NRK-52E 细胞
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miR-3587 Inhibitor Attenuates Ferroptosis Following Renal Ischemia-Reperfusion Through HO-1 (2022-01-03)
期刊：Frontiers in Molecular Biosciences
影响因子 ：6.1
引用产品： NRK-52E 细胞
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Exercise serum regulates uric acid transporters in normal rat kidney cells (2022-10-27)
期刊：Scientific Reports
DOI：10.1038/s41598-022-22570-w
影响因子 ：5.0
引用产品： NRK-52E 细胞
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Ferulic acid protects renal tubular epithelial cells against anoxia/reoxygenation injury mediated by AMPKα1 (2022-04-05)
期刊：FREE RADICAL RESEARCH
DOI：10.1080/10715762.2022.2062339
影响因子 ：3.3
引用产品： NRK-52E 细胞
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Upregulation of lncRNA NONRATG019935.2 suppresses the p53-mediated apoptosis of renal tubular epithelial cells in septic acute kidney injury (2021-11-01)
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-03953-9
影响因子 ：9.0
引用产品： NRK-52E 细胞
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Isorhynchophylline ameliorates paraquat-induced acute kidney injury by attenuating oxidative stress and mitochondrial damage via regulating toll-interacting expression (2021-04-08)
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2021.115521
影响因子 ：3.8
引用产品： NRK-52E 细胞
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Metadherin silencing results in the inhibition of pyroptosis in lipopolysaccharide/adenosine triphosphate ? stimulated renal tubular epithelial cells (2021-12-27)
期刊：Tissue & Cell
DOI：10.1016/j.tice.2021.101722
影响因子 ：2.6
引用产品： NRK-52E 细胞 , DMEM高糖 培养基
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Contribution of TFEB-mediated autophagy to tubulointerstitial fibrosis in mice with adenine-induced chronic kidney disease (2020-11-20)
期刊：Biomedicine & Pharmacotherapy
DOI：10.1016/j.biopha.2020.110949
影响因子 ：7.5
引用产品： NRK-52E 细胞
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Renoprotective ganodermaones A and B with rearranged meroterpenoid carbon skelotons from Ganoderma fungi (2020-05-14)
期刊：Bioorganic Chemistry
DOI：10.1016/j.bioorg.2020.103930
影响因子 ：5.1
引用产品： NRK-52E 细胞
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Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction (2019-02-19)
期刊：Molecular Medicine Reports
影响因子 ：3.4
引用产品： NRK-52E 细胞
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