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产品概述
名称 | HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确) |
别称 | Hk-2; HK2; Human Kidney-2 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | HK-2细胞属源于正常肾的近曲小管细胞,通过导入HPV-16 E6/E7基因而获得永生化。将含有HPV-16 E6/E7基因的重组的逆转录病毒载体pLXSN 16 E6/E7转染外生包装细胞Psi-2;Psi-2细胞产生的病毒再去感染兼嗜性包装细胞系PA317,最后将PA317细胞产生的病毒颗粒导入正常的肾皮质近曲小管细胞。尽管pLXSN 16 E6/E7中含有新霉素抗性,但未用G418筛选转导克隆。Southern和FISH分析显示,HK-2细胞来源于单克隆。PCR检测证实,HK-2细胞基因组中含有E6/E7基因。 |
年龄(性别) | 男性;成人 |
组织来源 | 肾,皮质/近端小管 |
细胞类型 | 转化细胞系 |
生物安全等级 | BSL-2 |
受体表达情况 | epidermal growth factor (EGF), expressed |
基因表达情况 | alkaline phosphatase; gamma glutamyltranspeptidase; leucine aminopeptidase; acid phosphatase; cytokeratin; alpha 3, beta 1 integrin; fibronectin |
保藏机构 | ATCC; CRL-2190 BCRC; 60097 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 13 D2S1338 17,25 D3S1358 16 D5S818 12 D7S820 10,11 D8S1179 10,14 D13S317 9 D16S539 12 D18S51 12 D19S433 15,15.2 D21S11 28,30 FGA 20 PentaD 9,12 PentaE 10,11 TH01 9 TPOX 8,9 vWA 17,18 D6S1043 12,13 D12S391 17.3,22 D2S441 11,12 -
STR鉴定图
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参考文献
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New Sight of Renal Toxicity Caused by UV-Aged Polystyrene Nanoplastics: Induced Ferroptosis via Adsorption of Transferrin (2024-01-04)
期刊:Small
影响因子 :13.3
引用产品: HK-2 细胞
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Artesunate-Nanoliposome-TPP, a Novel Drug Delivery System That Targets the Mitochondria, Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Stress and Inflammatory Effects (2024-02-11)
期刊:International Journal of Nanomedicine
影响因子 :8.0
引用产品: HK-2 细胞
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2-Dodecyl-6-Methoxycyclohexa-2, 5-Diene-1, 4-Dione isolated from Averrhoa carambola L. root inhibits high glucose-induced EMT in HK-2 cells through targeting the regulation of miR-21–5p/Smad7 signaling pathway (2024-02-17)
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2024.116280
影响因子 :7.5
引用产品: HK-2 细胞
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High CD133 expression in proximal tubular cells in diabetic kidney disease: good or bad? (2024-02-16)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-024-04950-0
影响因子 :7.4
引用产品: HK-2 细胞 , NRK-53E 细胞
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The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury (2024-01-02)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04793-1
影响因子 :7.4
引用产品: HK-2 细胞
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Urinary miR-185-5p is a biomarker of renal tubulointerstitial fibrosis in IgA nephropathy (2024-02-15)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2024.1326026
影响因子 :7.3
引用产品: HK-2 细胞
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Deubiquitinating enzyme OTUD4 stabilizes RBM47 to induce ATF3 transcription: a novel mechanism underlying the restrained malignant properties of ccRCC cells (2024-03-30)
期刊:APOPTOSIS
DOI:10.1007/s10495-024-01953-6
影响因子 :7.2
引用产品: HK-2 细胞 , Caki-1 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , SW839 细胞
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Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis (2024-03-14)
期刊:ACS Pharmacology & Translational Science
影响因子 :6.0
引用产品: HK-2 细胞
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Investigating HMGB1 as a Potential Serum Biomarker for Early Diabetic Nephropathy Monitoring by Quantitative Proteomics (2024-01-08)
期刊:iScience
DOI:10.1016/j.isci.2024.108834
影响因子 :5.8
引用产品: HK-2 细胞
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Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport (2024-03-04)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.4
引用产品: HK-2 细胞
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Inhibitory effect of Incarvillea diffusa Royle extract in the formation of calcium oxalate nephrolithiasis by regulating ROS-induced Nrf2/HO-1 pathway in rats (2024-01-23)
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.4
引用产品: HK-2 细胞
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Sleeve gastrectomy links the attenuation of diabetic kidney disease to the inhibition of renal tubular ferroptosis through down-regulating TGF-β1/Smad3 signaling pathway (2024-03-21)
期刊:JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
DOI:10.1007/s40618-023-02267-1
影响因子 :5.4
引用产品: HK-2 细胞
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HMGN1 down-regulation in the diabetic kidney attenuates tubular cells injury and protects against renal inflammation via suppressing MCP-1 and KIM-1 expression through TLR4 (2024-02-27)
期刊:JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
DOI:10.1007/s40618-023-02292-0
影响因子 :5.4
引用产品: HK-2 细胞
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Disulfideptosis-associated lncRNAs reveal features of prognostic, immune escape, tumor mutation, and tumor malignant progression in renal clear cell carcinoma (2024-02-08)
期刊:Aging-US
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , OS-RC-2 细胞 , A-498 细胞 , ACHN 细胞 , HK-2 细胞
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Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4 (2024-03-20)
期刊:CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 :5.1
引用产品: HK-2 细胞
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Arylacryl amides: Design, synthesis and the protection against cisplatin-induced acute kidney injury via TLR4/STING/NF-κB pathway (2024-03-21)
期刊:BIOORGANIC CHEMISTRY
DOI:10.1016/j.bioorg.2024.107303
影响因子 :5.1
引用产品: HK-2 细胞
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The copper transporter, SLC31A1, transcriptionally activated by ELF3, imbalances copper homeostasis to exacerbate cisplatin-induced acute kidney injury through mitochondrial dysfunction (2024-03-09)
期刊:CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 :5.1
引用产品: HK-2 细胞
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An aldose reductase inhibitor, WJ-39, ameliorates renal tubular injury in diabetic nephropathy by activating PINK1/Parkin signaling (2024-02-08)
期刊:EUROPEAN JOURNAL OF PHARMACOLOGY
DOI:10.1016/j.ejphar.2024.176376
影响因子 :5.0
引用产品: HK-2 细胞
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TMEM16A inhibits renal tubulointerstitial fibrosis via Wnt/β-catenin signaling during hypertension nephropathy (2024-02-03)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2024.111088
影响因子 :4.8
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Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis (2024-03-20)
期刊:Scientific Reports
DOI:10.1038/s41598-024-56950-1
影响因子 :4.6
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Qi-dan-dihuang decoction ameliorates renal fibrosis in diabetic rats via p38MAPK/AKT/mTOR signaling pathway (2024-03-08)
期刊:ENVIRONMENTAL TOXICOLOGY
影响因子 :4.5
引用产品: HK-2 细胞 , NRK-52E 细胞
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Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways (2024-02-08)
期刊:INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI:10.1016/j.biocel.2024.106549
影响因子 :4.0
引用产品: HK-2 细胞
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Disruption of Autophagic Flux and Treatment with the PDPK1 Inhibitor GSK2334470 Synergistically Inhibit Renal Cell Carcinoma Pathogenesis (2024-01-20)
期刊:Journal of Cancer
影响因子 :3.9
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞
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Excess iron accumulation mediated senescence in diabetic kidney injury (2024-03-14)
期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 :3.6
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Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC (2024-03-21)
期刊:GENE
DOI:10.1016/j.gene.2024.148403
影响因子 :3.5
引用产品: HK-2 细胞 , ACHN 细胞 , A-498 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , Caki-1 细胞 , RPMI-1640 培养基 , MEM 培养基
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Andrographolide attenuates sepsis-induced acute kidney injury by inhibiting ferroptosis through the Nrf2/FSP1 pathway. (2024-03-12)
期刊:FREE RADICAL RESEARCH
DOI:10.1080/10715762.2024.2330413
影响因子 :3.3
引用产品: HK-2 细胞
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CircACTR2 attenuated the effects of tetramethylpyrazine on human kidney cell injury (2024-03-01)
期刊:JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
DOI:10.1007/s10863-024-10001-6
影响因子 :3.0
引用产品: HK-2 细胞
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FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent manner (2024-03-06)
期刊:RENAL FAILURE
DOI:10.1080/0886022X.2024.2322037
影响因子 :3.0
引用产品: HK-2 细胞 , MEM (含NEAA) 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , Hank's平衡盐溶液 (HBSS),含钙、镁,不含酚红
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WTAP-mediated N6-methyladenosine modification promotes the inflammation, mitochondrial damage and ferroptosis of kidney tubular epithelial cells in acute kidney injury by regulating LMNB1 expression and activating NF-κB and JAK2/STAT3 pathways (2024-03-22)
期刊:JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
DOI:10.1007/s10863-024-10015-0
影响因子 :3.0
引用产品: HK-2 细胞 , 青霉素-链霉素溶液 (双抗),100×
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Decreased expression of TXNIP is associated with poor prognosis and immune infiltration in kidney renal clear cell carcinoma (2024-01-12)
期刊:Oncology Letters
影响因子 :2.9
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Clinical Significance of Apela in Acute Cardiorenal Insuffiency of Chronic Heart Failure (2024-01-18)
期刊:KIDNEY & BLOOD PRESSURE RESEARCH
影响因子 :2.8
引用产品: THP-1 细胞 , 人肾小球内皮细胞 , 人肾小球系膜细胞 , HK-2 细胞 , DMEM高糖 培养基 , 人肾小球内皮细胞完全培养基 , 人肾小球系膜细胞完全培养基 , 人肾小管上皮细胞完全培养基
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Knockdown of circ-Gatad1 alleviates LPS induced HK2 cell injury via targeting miR-22-3p/TRPM7 axis in septic acute kidney (2024-03-05)
期刊:BMC Nephrology
DOI:10.1186/s12882-024-03513-1
影响因子 :2.3
引用产品: HK-2 细胞 , MEM 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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Cytosolic mtDNA–cGAS–STING axis contributes to sepsis-induced acute kidney injury via activating the NLRP3 inflammasome (2024-01-19)
期刊:Clinical and Experimental Nephrology
DOI:10.1007/s10157-023-02448-5
影响因子 :2.3
引用产品: HK-2 细胞 , HK-2细胞专用培养基
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Cell division cycle 42 attenuates high glucose-treated renal tubular epithelial cell apoptosis, fibrosis, and inflammation, but activates the PAK1/AKT pathway (2024-02-28)
期刊:Clinical and Experimental Nephrology
DOI:10.1007/s10157-024-02468-9
影响因子 :2.3
引用产品: HK-2 细胞 , DMEM/F12 培养基 , 青霉素-链霉素溶液 (双抗),100×
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Ethanol extract of Abelmoschus manihot suppresses endoplasmic reticulum stress in contrast-induced nephropathy (2024-01-23)
期刊:Asian Pacific Journal of Tropical Biomedicine
影响因子 :1.7
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Hypoxia-triggered tumor specific glutamine inhibition for reversing cisplatin resistance of chemotherapy (2023-11-27)
期刊:CHEMICAL ENGINEERING JOURNAL
影响因子 :15.1
引用产品: A549 [A-549] 细胞 , A549/DDP 细胞 , 青霉素-链霉素溶液 (双抗),100× , HK-2 细胞
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Self-oriented ferritin nanocages mitigate iron overload-induced oxidative stress for acute kidney injury (2023-05-02)
期刊:CHEMICAL ENGINEERING JOURNAL
影响因子 :15.1
引用产品: HK-2 细胞
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Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition (2023-08-02)
期刊:Science Advances
影响因子 :13.6
引用产品: HK-2 细胞
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Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI (2023-03-21)
期刊:Theranostics
影响因子 :12.4
引用产品: HK-2 细胞
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Renal clearance of graphene oxide: glomerular filtration or tubular secretion and selective kidney injury association with its lateral dimension (2023-02-10)
期刊:JOURNAL OF NANOBIOTECHNOLOGY
DOI:10.1186/s12951-023-01781-x
影响因子 :10.2
引用产品: HK-2 细胞
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Liraglutide abrogates nephrotoxic effects of chemotherapies (2023-02-04)
期刊:PHARMACOLOGICAL RESEARCH
DOI:10.1016/j.phrs.2023.106680
影响因子 :9.3
引用产品: HK-2 细胞
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Aldehyde dehydrogenase 2 alleviates mitochondrial dysfunction by promoting PGC-1α-mediated biogenesis in acute kidney injury (2023-01-20)
期刊:Cell Death & Disease
DOI:10.1038/s41419-023-05557-x
影响因子 :9.0
引用产品: HK-2 细胞
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circWSB1 promotes tumor progression in ccRCC via circWSB1/miR-182-5p/WSB1 axis (2023-11-24)
期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI:10.1016/j.ijbiomac.2023.128338
影响因子 :8.2
引用产品: HK-2 细胞
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Inhibition of intrarenal PRR-RAS pathway by Ganoderma lucidum polysaccharide peptides in proteinuric nephropathy (2023-10-16)
期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI:10.1016/j.ijbiomac.2023.127336
影响因子 :8.2
引用产品: HK-2 细胞 , HK-2细胞专用培养基
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Nephroprotective Effects of Selenium Nanoparticles Against Sodium Arsenite-Induced Damages (2023-06-12)
期刊:International Journal of Nanomedicine
影响因子 :8.0
引用产品: HK-2 细胞
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Celastrol alleviated acute kidney injury by inhibition of ferroptosis through Nrf2/GPX4 pathway (2023-08-18)
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2023.115333
影响因子 :7.5
引用产品: MEM (含NEAA) 培养基 , 青霉素-链霉素溶液 (双抗),100× , 特级胎牛血清 , HK-2 细胞
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Jiedu Tongluo Baoshen formula enhances renal tubular epithelial cell autophagy to prevent renal fibrosis by activating SIRT1/LKB1/AMPK pathway (2023-02-03)
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2023.114340
影响因子 :7.5
引用产品: NRK-52E 细胞 , HK-2 细胞
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Inhibition of ACSF2 protects against renal ischemia/reperfusion injury via mediating mitophagy in proximal tubular cells (2023-02-09)
期刊:FREE RADICAL BIOLOGY AND MEDICINE
DOI:10.1016/j.freeradbiomed.2023.02.003
影响因子 :7.4
引用产品: HK-2 细胞
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TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage (2023-10-05)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04351-9
影响因子 :7.4
引用产品: HK-2 细胞 , MEM (含NEAA) 培养基
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Knockdown of NR3C1 inhibits the proliferation and migration of clear cell renal cell carcinoma through activating endoplasmic reticulum stress–mitophagy (2023-10-08)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04560-2
影响因子 :7.4
引用产品: HK-2 细胞
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Bioinformatics analysis reveals the potential role of matrix metalloproteinases in immunity and urolithiasis (2023-03-15)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1158379
影响因子 :7.3
引用产品: HK-2 细胞
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Prognostic and tumor microenvironmental feature of clear cell renal cell carcinoma revealed by m6A and lactylation modification-related genes (2023-08-11)
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1225023
影响因子 :7.3
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Discovery and Design of Novel Cyclic Peptides as Specific Inhibitors Targeting CCN2 and Disrupting CCN2/EGFR Interaction for Kidney Fibrosis Treatment (2023-06-06)
期刊:JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1021/acs.jmedchem.3c00594
影响因子 :7.3
引用产品: HK-2 细胞
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Hyperoside mediates protection from diabetes kidney disease by regulating ROS-ERK signaling pathway and pyroptosis (2023-08-30)
期刊:PHYTOTHERAPY RESEARCH
DOI:10.1002/ptr.7993
影响因子 :7.2
引用产品: HK-2 细胞
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Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway (2023-07-25)
期刊:Cell Death Discovery
DOI:10.1038/s41420-023-01564-1
影响因子 :7.0
引用产品: HK-2 细胞
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Seratrodast platinum(IV) hybrids efficiently inhibit cancer-related thrombosis and metastasis phenotype in vitro and in vivo (2023-09-18)
期刊:Inorganic Chemistry Frontiers
影响因子 :7.0
引用产品: A549 [A-549] 细胞 , A2780 细胞 , Hep G2 细胞 , AsPC-1 细胞 , HCT 116 细胞 , HK-2 细胞
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Human bone marrow mesenchymal stem cell-derived extracellular vesicles reduce inflammation and pyroptosis in acute kidney injury via miR-223-3p/HDAC2/SNRK (2023-01-14)
期刊:INFLAMMATION RESEARCH
DOI:10.1007/s00011-022-01653-4
影响因子 :6.7
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Systemic mutation of Ncf1 ameliorates obstruction-induced renal fibrosis while macrophage-rescued NCF1 further alleviates renal fibrosis (2023-06-30)
期刊:ANTIOXIDANTS & REDOX SIGNALING
影响因子 :6.6
引用产品: HK-2 细胞
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Novel Role of Hemeoxygenase-1 in Phthalate-Induced Renal Proximal Tubule Cell Ferroptosis (2023-01-25)
期刊:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 :6.1
引用产品: HK-2 细胞 , MEM (含NEAA) 培养基
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Ochratoxin A Induces Renal Cell Ferroptosis by Disrupting Iron Homeostasis and Increasing ROS (2023-12-22)
期刊:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 :6.1
引用产品: HK-2 细胞 , 青霉素-链霉素溶液 (双抗),100×
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Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota (2023-01-17)
期刊:Food & Function
影响因子 :6.1
引用产品: HK-2 细胞 , MEM (含NEAA) 培养基
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Identification of the H3K36me3 reader LEDGF/p75 in the pancancer landscape and functional exploration in clear cell renal cell carcinoma (2023-08-26)
期刊:Computational and Structural Biotechnology Journal
DOI:10.1016/j.csbj.2023.08.023
影响因子 :6.0
引用产品: Caki-1 细胞 , 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞
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Polystyrene nanoplastics induce apoptosis of human kidney proximal tubular epithelial cells via oxidative stress and MAPK signaling pathways (2023-10-04)
期刊:ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
DOI:10.1007/s11356-023-30155-x
影响因子 :5.8
引用产品: HK-2 细胞
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CIRP attenuates acute kidney injury after hypothermic cardiovascular surgery by inhibiting PHD3/HIF-1α-mediated ROS-TGF-β1/p38 MAPK activation and mitochondrial apoptotic pathways (2023-05-01)
期刊:MOLECULAR MEDICINE
DOI:10.1186/s10020-023-00655-0
影响因子 :5.7
引用产品: HK-2 细胞
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Exosome-mediated crosstalk between epithelial cells amplifies the cell injury cascade in CaOx stone formation (2023-02-28)
期刊:Journal of Biological Engineering
DOI:10.1186/s13036-023-00324-0
影响因子 :5.6
引用产品: HK-2 细胞
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LMCD1 is involved in tubulointerstitial inflammation in the early phase of renal fibrosis by promoting NFATc1-mediated NLRP3 activation (2023-06-11)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.110362
影响因子 :5.6
引用产品: HK-2 细胞
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Melatonin alleviates intrarenal CaOx crystals deposition through inhibiting LPS-induced non-canonical inflammasome-mediated renal tubular epithelial cells pyroptosis (2023-08-24)
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.110796
影响因子 :5.6
引用产品: HK-2 细胞 , HK-2细胞专用培养基
-
Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro (2023-01-26)
期刊:Frontiers in Endocrinology
DOI:10.3389/fendo.2022.1009507
影响因子 :5.2
引用产品: HK-2 细胞
-
Establishing a prognostic model based on five starvation-related long non-coding RNAs for clear cell renal cell carcinoma (2023-06-20)
期刊:Aging-US
影响因子 :5.2
引用产品: 786-O [786-0] 细胞 , Caki-1 细胞 , HK-2 细胞
-
Ferroptosis in calcium oxalate kidney stone formation and the possible regulatory mechanism of ANKRD1 (2023-03-11)
期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
DOI:10.1016/j.bbamcr.2023.119452
影响因子 :5.1
引用产品: HK-2 细胞 , HK-2细胞专用培养基
-
LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1–Induced Epithelial–Mesenchymal Transition in Human Kidney 2 Cells (2023-01-10)
期刊:LABORATORY INVESTIGATION
DOI:10.1016/j.labinv.2022.100016
影响因子 :5.0
引用产品: HK-2 细胞
-
Identification of a novel 5-methylcytosine-related signature for prognostic prediction of kidney renal papillary cell carcinoma and a Putative target for drug repurposing (2023-07-29)
期刊:Translational Oncology
DOI:10.1016/j.tranon.2023.101741
影响因子 :5.0
-
FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells (2023-09-02)
期刊:Journal of Translational Internal Medicine
影响因子 :4.9
-
Glycyrrhizic acid improves tacrolimus-induced renal injury by regulating autophagy (2023-01-23)
期刊:FASEB JOURNAL
影响因子 :4.8
引用产品: HK-2 细胞
-
Expression of gasdermin D in clear cell renal cell carcinoma and its effect on its biological function (2023-07-06)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: 786-O [786-0] 细胞 , 769-P 细胞 , HK-2 细胞
-
Tumor-associated M2 macrophages in the immune microenvironment influence the progression of renal clear cell carcinoma by regulating M2 macrophage-associated genes (2023-06-08)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: 786-O [786-0] 细胞 , HK-2 细胞 , THP-1 细胞 , 特级胎牛血清
-
A pan-cancer analysis of DDR1 in prognostic signature and tumor immunity, drug resistance (2023-04-08)
期刊:Scientific Reports
DOI:10.1038/s41598-023-27975-9
影响因子 :4.6
引用产品: HK-2 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞 , SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞 , RWPE-1 细胞 , PC-3 细胞 , DU 145 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , Ham's F-12K 培养基 , 人前列腺上皮细胞完全培养基
-
Protease-Activated Receptor-2 and Phospholipid Metabolism Analysis in Hyperuricemia-Induced Renal Injury (2023-07-13)
期刊:MEDIATORS OF INFLAMMATION
影响因子 :4.6
引用产品: HK-2 细胞
-
Ganoderic Acid A and Its Amide Derivatives as Potential Anti-Cancer Agents by Regulating the p53-MDM2 Pathway: Synthesis and Biological Evaluation (2023-03-04)
期刊:MOLECULES
影响因子 :4.6
引用产品: MCF7 [MCF-7] 细胞 , Hep G2 细胞 , SJSA-1 细胞 , HK-2 细胞
-
Norcantharidin-Encapsulated C60-Modified Nanomicelles: A Potential Approach to Mitigate Cytotoxicity in Renal Cells and Simultaneously Enhance Anti-Tumor Activity in Hepatocellular Carcinoma Cells (2023-11-15)
期刊:MOLECULES
影响因子 :4.6
引用产品: HK-2 细胞
-
Focusing on the Abnormal Events of NPC1, NPC2, and NPC1L1 in Pan-Cancer and Further Constructing LUAD and KICH Prediction Models (2023-12-18)
期刊:JOURNAL OF PROTEOME RESEARCH
DOI:10.1021/acs.jproteome.3c00655
影响因子 :4.4
引用产品: A549 [A-549] 细胞 , NCI-H1299 细胞 , HK-2 细胞 , A-498 细胞 , MEM 培养基 , RPMI-1640 培养基 , Ham's F-12K 培养基
-
The induction of ferroptosis by KLF11/NCOA4 axis: the inhibitory role in clear cell renal cell carcinoma (2023-08-29)
期刊:Human Cell
DOI:10.1007/s13577-023-00973-9
影响因子 :4.3
引用产品: HK-2 细胞 , 769-P 细胞 , McCoy's 5A 培养基
-
Silencing of adipocyte enhancer-binding protein 1 (AEBP1) alleviates renal fibrosis in vivo and in vitro via inhibition of the β-catenin signaling pathway (2023-02-04)
期刊:Human Cell
DOI:10.1007/s13577-023-00859-w
影响因子 :4.3
-
Zinc Oxide Nanoparticles Induce Renal Injury by Initiating Oxidative Stress, Mitochondrial Damage and Apoptosis in Renal Tubular Epithelial Cells (2023-04-29)
期刊:BIOLOGICAL TRACE ELEMENT RESEARCH
DOI:10.1007/s12011-023-03683-3
影响因子 :3.9
引用产品: HK-2 细胞
-
Mixed-ligand copper(II) hydrazone complexes: Synthesis, structure, and anti-lung cancer properties (2023-01-19)
期刊:JOURNAL OF MOLECULAR STRUCTURE
DOI:10.1016/j.molstruc.2023.134986
影响因子 :3.8
引用产品: A549 [A-549] 细胞 , A549/DDP 细胞 , HK-2 细胞
-
Identification of an unrecognized circRNA associated with development of renal fibrosis (2023-01-04)
期刊:Frontiers in Genetics
影响因子 :3.7
引用产品: HK-2 细胞
-
Nephropathy Is Aggravated by Fatty Acids in Diabetic Kidney Disease through Tubular Epithelial Cell Necroptosis and Is Alleviated by an RIPK-1 Inhibitor (2023-03-17)
期刊:Kidney Diseases
影响因子 :3.7
引用产品: HK-2 细胞
-
Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential therapeutic target AJAP1 (2023-05-29)
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-023-04877-x
影响因子 :3.6
引用产品: HK-2 细胞 , Caki-1 细胞 , OS-RC-2 细胞
-
Circ_0006944 aggravates LPS-induced HK2 cell injury via modulating miR-205-5p/UBL4A pathway (2023-11-22)
期刊:AUTOIMMUNITY
DOI:10.1080/08916934.2023.2276066
影响因子 :3.5
引用产品: HK-2 细胞
-
A latent reversible ratiometric optical pH sensing probe based on phenylboronic acid for alkaline pH detection and applications in test paper and alkalotic HK-2 cells (2023-05-10)
期刊:NEW JOURNAL OF CHEMISTRY
影响因子 :3.3
引用产品: HK-2 细胞
-
Knockdown of KLF5 ameliorates renal fibrosis in MRL/lpr mice via inhibition of MX1 transcription (2023-07-27)
期刊:Immunity Inflammation and Disease
DOI:10.1002/iid3.937
影响因子 :3.2
引用产品: HK-2 细胞
-
Circ_0068087 knockdown attenuates high-glucose-induced human tubular epithelial cell injury in a microribonucleic acid/progestin and adipoQ receptor 3-dependent manner in diabetic nephropathy (2023-11-20)
期刊:Journal of Diabetes Investigation
影响因子 :3.2
引用产品: HK-2 细胞 , MEM (含NEAA) 培养基
-
CircUSP42 ameliorates LPS-induced human renal epithelial cells in vitro by regulating the miR-182-5p/DUSP1 axis (2023-10-17)
期刊:SHOCK
DOI:10.1097/SHK.0000000000002229
影响因子 :3.1
引用产品: HK-2 细胞
-
Exosomal circVMA21 derived from adipose-derived stem cells alleviates sepsis-induced acute kidney injury by targeting miR-16-5p (2023-07-12)
期刊:SHOCK
DOI:10.1097/SHK.0000000000002179
影响因子 :3.1
引用产品: 小鼠脂肪间充质干细胞成骨诱导分化培养基 , 小鼠脂肪间充质干细胞成脂诱导分化培养基 , HK-2 细胞
-
CircNRIP1 KNOCKDOWN ALLEVIATES LIPOPOLYSACCHARIDE-INDUCED HUMAN KIDNEY 2 CELL APOPTOSIS AND INFLAMMATION THROUGH miR-339-5p/OXSR1 PATHWAY (2023-03-26)
期刊:SHOCK
DOI:10.1097/SHK.0000000000002057
影响因子 :3.1
引用产品: HK-2 细胞
-
MicroRNA-192-5p downregulates Fat Mass and Obesity-associated Protein to aggravate renal ischemia/reperfusion injury (2023-12-22)
期刊:RENAL FAILURE
DOI:10.1080/0886022X.2023.2285869
影响因子 :3.0
引用产品: HK-2 细胞
-
Exploratory metabolomic analysis based on UHPLC-Q-TOF-MS/MS to study hypoxia-reoxygenation energy metabolic alterations in HK-2 cells (2023-05-29)
期刊:RENAL FAILURE
DOI:10.1080/0886022X.2023.2186715
影响因子 :3.0
引用产品: HK-2 细胞
-
TIGAR protects against adenine-induced ferroptosis in human proximal tubular epithelial cells by activating the mTOR/S6KP70 axis (2023-05-04)
期刊:NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
DOI:10.1080/01635581.2023.2203353
影响因子 :2.9
引用产品: HK-2 细胞
-
Anemonin inhibits sepsis-induced acute kidney injury via mitigating inflammation and oxidative stress (2023-08-17)
期刊:BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
DOI:10.1002/bab.2504
影响因子 :2.8
引用产品: HK-2 细胞
-
Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress (2023-07-20)
期刊:BMC Molecular and Cell Biology
DOI:10.1186/s12860-023-00485-2
影响因子 :2.8
引用产品: HK-2 细胞
-
Liuwei Dihuang Decoction Drug-containing Serum Attenuates Transforming Growth Factor-β1-induced Epithelial-mesenchymal Transition in HK-2 Cells by Inhibiting NF-κB/Snail Signaling Pathway (2023-03-24)
期刊:CURRENT PHARMACEUTICAL BIOTECHNOLOGY
DOI:10.2174/1389201024666230228100718
影响因子 :2.8
引用产品: HK-2 细胞 , DMEM高糖 培养基 , 特级胎牛血清
-
Shen Qi Wan-Containing Serum Alleviates Renal Interstitial Fibrosis via Restraining Notch1-Mediated Epithelial-Mesenchymal Transition (2023-02-06)
期刊:Evidence-based Complementary and Alternative Medicine
影响因子 :2.7
引用产品: HK-2 细胞 , HK-2细胞专用培养基
-
Circ_0068087 Promotes High Glucose-Induced Human Renal Tubular Cell Injury through Regulating miR-106a-5p/ROCK2 Pathway (2023-04-20)
期刊:NEPHRON
影响因子 :2.5
-
Resveratrol Inhibits circ_0074371-related Pathway to Alleviate Sepsis-induced Acute Kidney Injury (2023-09-20)
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-023-10517-3
影响因子 :2.4
引用产品: HK-2 细胞
-
Coptisine mitigates diabetic nephropathy via repressing the NRLP3 inflammasome (2023-05-11)
期刊:Open Life Sciences
影响因子 :2.2
-
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation (2023-12-21)
期刊:Translational Andrology and Urology
影响因子 :2.0
引用产品: HK-2 细胞 , MEM (含NEAA) 培养基
-
GDF11, a target of miR-32-5p, suppresses high-glucose-induced mitochondrial dysfunction and apoptosis in HK-2 cells through PI3K/AKT signaling activation (2023-02-07)
期刊:INTERNATIONAL UROLOGY AND NEPHROLOGY
DOI:10.1007/s11255-023-03495-3
影响因子 :2.0
引用产品: HK-2 细胞
-
The damage mechanism of uranium(VI) to HK-2 cells (2023-03-01)
期刊:JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
DOI:10.1007/s10967-023-08843-2
影响因子 :1.6
引用产品: HK-2 细胞
-
A Water-Soluble AIEgen for Noninvasive Diagnosis of Kidney Fibrosis via SWIR Fluorescence and Photoacoustic Imaging (2022-10-12)
期刊:ADVANCED MATERIALS
影响因子 :32.1
引用产品: HK-2 细胞
-
Adropin Carried by Reactive Oxygen Species-Responsive Nanocapsules Ameliorates Renal Lipid Toxicity in Diabetic Mice (2022-08-11)
期刊:ACS Applied Materials & Interfaces
影响因子 :10.4
引用产品: HK-2 细胞
-
Protective effects of Polygonatum kingianum polysaccharides and aqueous extract on uranium-induced toxicity in human kidney (HK-2) cells (2001-02-20)
期刊:International Journal Of Biological Macromolecules
DOI:10.1016/j.ijbiomac.2022.01.043
影响因子 :8.2
引用产品: HK-2 细胞
-
6-Shogaol Exhibits a Promoting Effect with Tax via Binding HSP60 in Non-Small-Cell Lung Cancer (2022-11-19)
期刊:Cells
影响因子 :7.7
引用产品: A-375 细胞 , A549 [A-549] 细胞 , H8 细胞 , U251 细胞 , 3T3-L1 细胞 , PANC-1 细胞 , TSSCA 细胞 , HK-2 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基
-
Dioscin Protects against Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling (2022-12-11)
期刊:Antioxidants
影响因子 :7.7
引用产品: HK-2 细胞
-
Aluminum exposure induces nephrotoxicity via fibrosis and apoptosis through the TGF-β1/Smads pathway in vivo and in vitro (2022-12-13)
期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI:10.1016/j.ecoenv.2022.114422
影响因子 :7.1
引用产品: HK-2 细胞
-
Tumor Cell-Derived Exosomal circ-PRKCI Promotes Proliferation of Renal Cell Carcinoma via Regulating miR-545-3p/CCND1 Axis (2022-12-25)
期刊:Cancers
影响因子 :6.6
引用产品: 786-O [786-0] 细胞 , ACHN 细胞 , Caki-1 细胞 , 769-P 细胞 , HK-2 细胞
-
Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis. (2022-09-21)
期刊:Frontiers in Pharmacology
影响因子 :6.0
引用产品: SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞 , HK-2 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞 , RWPE-1 细胞 , PC-3 细胞 , DU 145 细胞 , Ham's F-12K 培养基 , DMEM高糖 培养基 , 人前列腺上皮细胞完全培养基 , RPMI-1640 培养基
-
Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway (2022-10-07)
期刊:Frontiers in Pharmacology
影响因子 :6.0
引用产品: HK-2 细胞
-
T-2 Toxin Induces Kidney Fibrosis via the mtROS-NLRP3-Wnt/β-Catenin Axis (2022-10-14)
期刊:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 :5.9
引用产品: HK-2 细胞 , 青霉素-链霉素溶液 (双抗),100×
-
Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA‑binding protein RBFOX1 in this disease (2001-02-20)
期刊:International Journal Of Molecular Medicine
影响因子 :5.4
引用产品: HK-2 细胞
-
Up-regulation of the human-specific CHRFAM7A gene protects against renal fibrosis in mice with obstructive nephropathy (2022-12-07)
期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 :5.3
引用产品: HK-2 细胞
-
Chronic intermittent hypoxia induces the pyroptosis of renal tubular epithelial cells by activating the NLRP3 inflammasome (2003-02-20)
期刊:Bioengineered
DOI:10.1080/21655979.2022.2047394
影响因子 :4.9
引用产品: HK-2 细胞
-
Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma (2022-02-16)
期刊:Journal of Inflammation Research
影响因子 :4.5
引用产品: Caki-1 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , ACHN 细胞 , HK-2 细胞
-
Role of (Pro)Renin Receptor in Cyclosporin A-Induced Nephropathy (2001-02-20)
期刊:AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
DOI:10.1152/ajprenal.00332.2021
影响因子 :4.2
引用产品: HK-2 细胞
-
Knockdown of circ_0003928 ameliorates high glucose-induced dysfunction of human tubular epithelial cells through the miR-506-3p/ HDAC4 pathway in diabetic nephropathy (2004-02-20)
期刊:EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI:10.1186/s40001-022-00679-y
影响因子 :4.2
引用产品: HK-2 细胞
-
Downregulation of circ-ZNF644 alleviates LPS-induced HK2 cell injury via miR-335-5p/HIPK1 axis (2022-09-02)
期刊:ENVIRONMENTAL TOXICOLOGY
影响因子 :4.1
-
CircZNF644 aggravates lipopolysaccharide-induced HK-2 cell impairment via the miR-140-5p/MLKL axis (2022-08-17)
期刊:JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
DOI:10.1007/s10863-022-09946-3
影响因子 :3.9
引用产品: HK-2 细胞 , MEM 培养基 , 青霉素-链霉素溶液 (双抗),100× , 特级胎牛血清
-
Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate (2004-02-20)
期刊:CELL STRESS & CHAPERONES
DOI:10.1007/s12192-022-01266-0
影响因子 :3.8
引用产品: 293 [HEK-293] 细胞 , HK-2 细胞
-
Identifying the mechanisms and molecular targets of Hongjingtian injection on treatment of TGFβ1-induced HK-2 cells: coupling network pharmacology with experimental verification (2022-12-01)
期刊:Annals of Translational Medicine
影响因子 :3.6
引用产品: HK-2 细胞
-
High-glucose induced toxicity in HK-2 cells can be alleviated by inhibition of miRNA-320c (2022-08-15)
期刊:RENAL FAILURE
DOI:10.1080/0886022X.2022.2106874
影响因子 :3.2
引用产品: HK-2 细胞
-
Silencing circ_0074371 inhibits the progression of sepsis-induced acute kidney injury by regulating miR-330-5p/ELK1 axis (2022-08-22)
期刊:MAMMALIAN GENOME
DOI:10.1007/s00335-022-09961-0
影响因子 :3.2
引用产品: HK-2 细胞 , 青霉素-链霉素溶液 (双抗),100×
-
High Glucose-Induced Human Kidney Cell Apoptosis and Inflammatory Injury Are Alleviated by Circ_0008529 Knockdown via Circ_0008529-Mediated miR-485-5p/WNT2B Signaling (2022-08-01)
期刊:APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
DOI:10.1007/s12010-022-04088-z
影响因子 :3.1
引用产品: HK-2 细胞
-
Forkhead box A2-mediated lncRNA SOX2OT up-regulation alleviates oxidative stress and apoptosis of renal tubular epithelial cells by promoting SIRT1 expression in diabetic nephropathy (2022-12-28)
期刊:NEPHROLOGY
影响因子 :2.4
引用产品: HK-2 细胞
-
LncRNA NEAT1 knockdown ameliorates LPS-induced human kidney injury by mediating the miR-330-5p/FOXO3 axis (2004-02-20)
期刊:INTERNATIONAL UROLOGY AND NEPHROLOGY
DOI:10.1007/s11255-022-03179-4
影响因子 :2.0
引用产品: HK-2 细胞
-
Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression (2022-11-30)
期刊:TRANSPLANT IMMUNOLOGY
DOI:10.1016/j.trim.2022.101764
影响因子 :2.0
引用产品: HK-2 细胞 , OS-RC-2 细胞 , ACHN 细胞 , 786-O [786-0] 细胞
-
A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy (2007-01-20)
期刊:Journal Of Colloid And Interface Science
DOI:10.1016/j.jcis.2021.07.080
影响因子 :9.9
引用产品: HK-2 细胞
-
Liproxstatin-1 attenuates unilateral ureteral obstruction-induced renal fibrosis by inhibiting renal tubular epithelial cells ferroptosis (2009-01-20)
期刊:Cell Death & Disease
DOI:10.1038/s41419-021-04137-1
影响因子 :9.0
引用产品: HK-2 细胞
-
A nanosensor for precise discrimination of nephrotoxic drug mechanisms via dynamic fluorescence fingerprint strategy (2003-01-20)
期刊:Analytica Chimica Acta
影响因子 :6.2
引用产品: MEM非必需氨基酸溶液 (NEAA),100× , HK-2 细胞
-
Senkyunolide I alleviates renal Ischemia-Reperfusion injury by inhibiting oxidative stress, endoplasmic reticulum stress and apoptosis (2011-01-20)
期刊:International Immunopharmacology
DOI:10.1016/j.intimp.2021.108393
影响因子 :5.6
引用产品: HK-2 细胞 , MEM (含NEAA) 培养基 , 青霉素-链霉素溶液 (双抗),100× , 特级胎牛血清
-
Migration of Human Renal Tubular Epithelial Cells in Response to Physiological Electric Signals (2009-01-20)
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.5
引用产品: HK-2 细胞 , 293 [HEK-293] 细胞
-
Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway (2007-01-20)
期刊:Journal Of Ethnopharmacology
影响因子 :5.4
引用产品: HK-2 细胞
-
MicroRNA 181a-2-3p Alleviates the Apoptosis of Renal Tubular Epithelial Cells via Targeting GJB2 in Sepsis-Induced Acute Kidney Injury | Molecular and Cellular Biology (2006-01-20)
期刊:Molecular And Cellular Biology
影响因子 :5.3
引用产品: HK-2 细胞
-
Downregulation of IRF2 Alleviates Sepsis-Related Acute Kidney Injury in vitro and in vivo (2012-01-20)
期刊:Drug Design Development and Therapy
影响因子 :4.8
引用产品: HK-2 细胞
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Knockdown of circ-FANCA alleviates LPS-induced HK2 cell injury via targeting miR-93-5p/OXSR1 axis in septic acute kidney injury (2001-01-20)
期刊:Diabetology & Metabolic Syndrome
DOI:10.1186/s13098-021-00625-8
影响因子 :4.8
引用产品: HK-2 细胞 , MEM (含NEAA) 培养基
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Anti-Malignant Ascites Effect of Total Diterpenoids from Euphorbiae ebracteolatae Radix Is Attributable to Alterations of Aquaporins via Inhibiting PKC Activity in the Kidney (2002-01-20)
期刊:Molecules
影响因子 :4.6
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Overexpression of TOLLIP Protects against Acute Kidney Injury after Paraquat Intoxication through Inhibiting NLRP3 Inflammasome Activation Modulated by Toll-Like Receptor 2/4 Signaling (2007-01-20)
期刊:Mediators Of Inflammation
影响因子 :4.6
引用产品: HK-2 细胞
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Metabolomics analysis underlay mechanisms in the renal impairment of mice caused by combination of aflatoxin M1 and ochratoxin A (2006-01-20)
期刊:Toxicology
影响因子 :4.5
引用产品: HK-2 细胞
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Loganin Attenuates Septic Acute Renal Injury with the Participation of AKT and Nrf2/HO-1 Signaling Pathways (2002-01-20)
期刊:Drug Design Development and Therapy
影响因子 :4.3
引用产品: HK-2 细胞
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The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi-omics study (2011-01-20)
期刊:Cancer Medicine
影响因子 :4.0
引用产品: 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞
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HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma (2002-01-20)
期刊:Cell Biology International
影响因子 :3.9
引用产品: HK-2 细胞 , A-498 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞
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CircVMA21 ameliorates lipopolysaccharide (LPS)-induced HK-2 cell injury depending on the regulation of miR-7-5p/PPARA (2012-01-20)
期刊:Autoimmunity
DOI:10.1080/08916934.2021.2012764
影响因子 :3.5
引用产品: HK-2 细胞 , 青霉素-链霉素溶液 (双抗),100× , 特级胎牛血清
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Circular RNA circ_0068,888 protects against lipopolysaccharide-induced HK-2 cell injury via sponging microRNA-21–5p (2002-01-20)
期刊:Biochemical And Biohysical Research Communicattons
DOI:10.1016/j.bbrc.2020.12.018
影响因子 :3.1
引用产品: HK-2 细胞
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LncRNA NKILA knockdown promotes cell viability and represses cell apoptosis, autophagy and inflammation in lipopolysaccharide-induced sepsis model by regulating miR-140-5p/CLDN2 axis (2004-01-20)
期刊:Biochemical and Biophysical Research Communications
DOI:10.1016/j.bbrc.2021.04.074
影响因子 :3.1
引用产品: 293T [HEK-293T] 细胞 , HK-2 细胞
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Aldosterone Induces the Proliferation of Renal Tubular Epithelial Cells In Vivo but Not In Vitro (2007-01-20)
期刊:Journal Of The Renin-Angiotensin-Aldosterone System
影响因子 :2.9
引用产品: HK-2 细胞
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Identification of hub genes and transcription factor-miRNA-mRNA pathways in mice and human renal ischemia-reperfusion injury (2010-01-20)
期刊:PeerJ
影响因子 :2.7
引用产品: HK-2 细胞
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Thioredoxin relieves lipopolysaccharide‑induced acute kidney injury in mice by reducing inflammation, oxidative stress and apoptosis (2004-01-20)
期刊:Experimental and Therapeutic Medicine
影响因子 :2.7
引用产品: HK-2 细胞
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Long Non-Coding RNA CASC2 Overexpression Ameliorates Sepsis-Associated Acute Kidney Injury by Regulating MiR-545-3p/PPARA axis (2005-01-20)
期刊:Journal of Surgical Research
影响因子 :2.2
引用产品: HK-2 细胞 , 293 [HEK-293] 细胞
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Advanced Oxidation Protein Product Promotes Oxidative Accentuation in Renal Epithelial Cells via the Soluble (Pro)renin Receptor-Mediated Intrarenal Renin-Angiotensin System and Nox4-H2O2 Signaling (2011-01-20)
期刊:Oxidative Medicine and Cellular Longevity
影响因子 :0.0
引用产品: HK-2 细胞 , DMEM/F12 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway (2008-00-20)
期刊:Cell Death & Disease
DOI:10.1038/s41419-020-02912-0
影响因子 :9.0
引用产品: HK-2 细胞
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Involvement of miR‐27a‐3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress (2007-00-20)
期刊:Journal Of Cellular Physiology
影响因子 :5.6
引用产品: HK-2 细胞
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Sodium butyrate ameliorates deoxycorticosterone acetate/salt-induced hypertension and renal damage by inhibiting the MR/SGK1 pathway (2009-00-20)
期刊:Hypertension Research
DOI:10.1038/s41440-020-00548-3
影响因子 :5.4
引用产品: HK-2 细胞 , 青霉素-链霉素溶液 (双抗),100×
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Soluble (pro)renin receptor promotes the fibrotic response in renal proximal tubule epithelial cells in vitro via the Akt/β-catenin/Snail signaling pathway (2011-00-20)
期刊:American Journal Of Physiology-Renal Physiology
DOI:10.1152/ajprenal.00197.2020
影响因子 :4.2
引用产品: HK-2 细胞
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Rapid and sensitive detection of NGAL for the prediction of acute kidney injury via a polydopamine nanosphere/aptamer nanocomplex coupled with DNase I-assisted recycling amplification (2004-00-20)
期刊:Analyst
影响因子 :4.2
引用产品: HK-2 细胞
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δ‐Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β‐catenin nuclear localization and activating its downstream target genes (2001-00-20)
期刊:Cancer Medicine
影响因子 :4.0
引用产品: HK-2 细胞 , A-498 细胞 , ACHN 细胞 , 786-O [786-0] 细胞
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Hydroxytyrosol inhibits apoptosis in ischemia/reperfusion-induced acute kidney injury via activating Sonic Hedgehog signaling pathway (2012-00-20)
期刊:European Review for Medical and Pharmacological Sciences
DOI:10.26355/eurrev_202012_24032
影响因子 :3.8
引用产品: HK-2 细胞
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Comprehensive analysis of the HOXA gene family identifes HOXA13as a novel oncogenic gene in kidney renal clear cell carcinoma (2005-00-20)
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-020-03259-x
影响因子 :3.6
引用产品: 786-O [786-0] 细胞 , Caki-1 细胞 , A-498 细胞 , HK-2 细胞
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MiR-32-5p knockdown inhibits epithelial to mesenchymal transition and renal fibrosis by targeting SMAD7 in diabetic nephropathy: (2009-00-20)
期刊:Human & Experimental Toxicology
影响因子 :2.8
引用产品: HK-2 细胞
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Efficacy of Obcordata A from Aspidopterys obcordata on Kidney Stones by Inhibiting NOX4 Expression (2003-09-20)
期刊:Molecules
影响因子 :4.6
引用产品: HK-2 细胞
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Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation (2019-11-21)
期刊:Yonsei Med J
DOI:10.3349/ymj.2019.60.12.1195
影响因子 :2.4
引用产品: HK-2 细胞
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Rhodomyrtosone B, a membrane-targeting anti-MRSA natural acylgphloroglucinol from Rhodomyrtus tomentosa (2009-08-20)
期刊:Journal Of Ethnopharmacology
影响因子 :5.4
引用产品: HK-2 细胞
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(Pro)renin receptor mediates albumin-induced cellular responses: role of site-1 protease-derived soluble (pro)renin receptor in renal epithelial cells (2012-07-20)
期刊:American Journal of Physiology-Cell Physiology
DOI:10.1152/ajpcell.00006.2017
影响因子 :5.5
引用产品: HK-2 细胞
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