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产品概述
| 名称 | HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确) |
| 别称 | Hk-2; HK2; Human Kidney-2 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | HK-2细胞属源于正常肾的近曲小管细胞，通过导入HPV-16 E6/E7基因而获得永生化。将含有HPV-16 E6/E7基因的重组的逆转录病毒载体pLXSN 16 E6/E7转染外生包装细胞Psi-2；Psi-2细胞产生的病毒再去感染兼嗜性包装细胞系PA317，最后将PA317细胞产生的病毒颗粒导入正常的肾皮质近曲小管细胞。尽管pLXSN 16 E6/E7中含有新霉素抗性，但未用G418筛选转导克隆。Southern和FISH分析显示，HK-2细胞来源于单克隆。PCR检测证实，HK-2细胞基因组中含有E6/E7基因。 |
| 年龄（性别） | 男性；成人 |
| 组织来源 | 肾，皮质/近端小管 |
| 细胞类型 | 转化细胞系 |
| 生物安全等级 | BSL-2 |
| 受体表达情况 | epidermal growth factor (EGF), expressed |
| 基因表达情况 | alkaline phosphatase; gamma glutamyltranspeptidase; leucine aminopeptidase; acid phosphatase; cytokeratin; alpha 3, beta 1 integrin; fibronectin |
| 保藏机构 | ATCC; CRL-2190 BCRC; 60097 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 13 D2S1338 17,25 D3S1358 16 D5S818 12 D7S820 10,11 D8S1179 10,14 D13S317 9 D16S539 12 D18S51 12 D19S433 15,15.2 D21S11 28,30 FGA 20 PentaD 9,12 PentaE 10,11 TH01 9 TPOX 8,9 vWA 17,18 D6S1043 12,13 D12S391 17.3,22 D2S441 11,12 -
STR鉴定图
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参考文献
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CHAC1 Mediates Endoplasmic Reticulum Stress-Dependent Ferroptosis in Calcium Oxalate Kidney Stone Formation (2025-01-21)
期刊：Advanced Science
影响因子 ：14.3
引用产品： HK-2 细胞
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Deletion of Pyruvate Carboxylase in Tubular Epithelial Cell Promotes Renal Fibrosis by Regulating SQOR/cGAS/STING-Mediated Glycolysis (2025-01-21)
期刊：Advanced Science
影响因子 ：14.3
引用产品： HK-2 细胞
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Butyrolactone I blocks the transition of acute kidney injury to chronic kidney disease in mice by targeting JAK1 (2025-01-21)
期刊：MedComm
影响因子 ：10.7
引用产品： HK-2 细胞 , NRK-52E 细胞
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Activation of autophagy with PF-06409577 alleviates heatstroke-induced organ injury (2025-01-19)
期刊：ENVIRONMENT INTERNATIONAL
DOI：10.1016/j.envint.2025.109285
影响因子 ：10.3
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HIF-2α/LPCAT1 orchestrates the reprogramming of lipid metabolism in ccRCC by modulating the FBXW7-mediated ubiquitination of ACLY (2025-01-01)
期刊：International Journal of Biological Sciences
影响因子 ：8.2
引用产品： 786-O [786-0] 细胞 , OS-RC-2 细胞 , A-498 细胞 , ACHN 细胞 , Caki-1 细胞 , HK-2 细胞 , 293T [HEK-293T] 细胞
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IGF1R Enhances Calcium Oxalate Monohydrate-Induced Epithelial-Mesenchymal Transition by Reprogramming Metabolism via the JAK2/STAT3 Signaling (2025-01-01)
期刊：International Journal of Biological Sciences
影响因子 ：8.2
引用产品： HK-2 细胞 , HK-2细胞专用培养基
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Senescent renal tubular cells derived extracellular vesicles transported miR-20a and miR-21 induced macrophage-to-myofibroblast transition in renal fibrosis after ischemia reperfusion injury (2025-01-06)
期刊：International Journal of Biological Sciences
影响因子 ：8.2
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Hypoxia-triggered ERRα acetylation enhanced its oncogenic role and promoted progression of renal cell carcinoma by coordinating autophagosome-lysosome fusion (2025-01-16)
期刊：Cell Death & Disease
DOI：10.1038/s41419-025-07345-1
影响因子 ：8.1
引用产品： HK-2 细胞 , ACHN 细胞 , A-498 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , 293T [HEK-293T] 细胞
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Identification of key antifibrotic targets FPR1, TAS2R5, and LRP2BP of valsartan in diabetic nephropathy: A transcriptomics-driven study integrating machine learning, molecular docking, and dynamics simulations (2025-01-13)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2025.139842
影响因子 ：7.7
引用产品： HK-2 细胞
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Senolytic procyanidin C1 alleviates renal fibrosis by promoting apoptosis of senescent renal tubular epithelial cells (2025-01-29)
期刊：FASEB JOURNAL
影响因子 ：4.4
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Danshen injection ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibiting ferroptosis via activating SIRT1/GPX4 pathway (2025-01-13)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2024.1503628
影响因子 ：4.4
引用产品： HK-2 细胞
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Renal Tubular Epithelial Cell–Derived hsa_circ_0008925 From Urine Is Related to Chronic Renal Fibrosis (2025-01-12)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：4.3
引用产品： HK-2 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液（双抗），100×
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Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease (2025-01-14)
期刊：Frontiers in Bioengineering and Biotechnology
DOI：10.3389/fbioe.2024.1506909
影响因子 ：4.3
引用产品： HK-2 细胞
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Exploring Liraglutide’s mechanism in reducing renal fibrosis: the Fsp1-CoQ10-NAD(P)H pathway (2025-01-12)
期刊：Scientific Reports
DOI：10.1038/s41598-025-85658-z
影响因子 ：3.8
引用产品： HK-2 细胞
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Identifying ADME-related gene signature for immune landscape and prognosis in KIRC by single-cell and spatial transcriptome analysis (2025-01-08)
期刊：Scientific Reports
DOI：10.1038/s41598-024-84018-7
影响因子 ：3.8
引用产品： Caki-1 细胞 , 786-O [786-0] 细胞 , HK-2 细胞
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S1R mediates NRF2 dependent ferroptosis of renal tubular epithelial cells to promote renal fibrosis in diabetic nephropathy (2025-01-27)
期刊：International Journal of Medical Sciences
影响因子 ：3.2
引用产品： HK-2 细胞
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Piezo1 aggravates ischemia/reperfusion-induced acute kidney injury by Ca2+-dependent calpain/HIF-1α/Notch signaling (2025-01-08)
期刊：RENAL FAILURE
DOI：10.1080/0886022X.2024.2447801
影响因子 ：3.0
引用产品： HK-2 细胞
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LncRNA TMC3-AS1 silence alleviates lipopolysaccharide-induced acute kidney injury by suppressing Wnt5a-mediated autophagy and pyroptosis pathway (2025-01-21)
期刊：MOLECULAR AND CELLULAR PROBES
影响因子 ：2.3
引用产品： HK-2 细胞
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Alpiniae oxyphyllae Fructus ameliorates renal lipid accumulation in diabetic kidney disease via activating PPARα (2025-01-17)
期刊：Asian Pacific Journal of Tropical Biomedicine
DOI：10.4103/apjtb.apjtb_703_24
影响因子 ：1.7
引用产品： MEM 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液（双抗），100× , HK-2 细胞
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RBBP6-Mediated ERRα Degradation Contributes to Mitochondrial Injury in Renal Tubular Cells in Diabetic Kidney Disease (2024-10-23)
期刊：Advanced Science
影响因子 ：14.3
引用产品： HK-2 细胞
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Aldehyde Dehydrogenase 2 Lactylation Aggravates Mitochondrial Dysfunction by Disrupting PHB2 Mediated Mitophagy in Acute Kidney Injury (2024-12-31)
期刊：Advanced Science
影响因子 ：14.3
引用产品： HK-2 细胞
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The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy (2024-08-13)
期刊：CELL DEATH AND DIFFERENTIATION
DOI：10.1038/s41418-024-01357-8
影响因子 ：13.7
引用产品： 人肾小球内皮细胞 , HK-2细胞专用培养基 , HK-2 细胞 , 人肾小球内皮细胞完全培养基
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New Sight of Renal Toxicity Caused by UV-Aged Polystyrene Nanoplastics: Induced Ferroptosis via Adsorption of Transferrin (2024-01-04)
期刊：Small
影响因子 ：13.3
引用产品： HK-2 细胞
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Human umbilical cord mesenchymal stem cells derived extracellular vesicles ameliorate kidney ischemia-reperfusion injury by suppression of senescent tubular epithelial cells - Experimental Study (2024-09-05)
期刊：International Journal of Surgery
DOI：10.1097/JS9.0000000000002074
影响因子 ：12.5
引用产品： HK-2 细胞
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Multivalent supramolecular fluorescent probes for accurate disease imaging (2024-10-18)
期刊：Science Advances
影响因子 ：11.7
引用产品： RAW 264.7 细胞 , LX-2 细胞 , CT26.WT 细胞 , HK-2 细胞 , AML12 细胞
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Silibinin Attenuates Ferroptosis in Acute Kidney Injury by Targeting FTH1 (2024-09-20)
期刊：Redox Biology
DOI：10.1016/j.redox.2024.103360
影响因子 ：10.7
引用产品： HK-2 细胞 , NRK-52E 细胞 , 小鼠肾小管上皮细胞
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Partial reduction of interleukin-33 signaling improves senescence and renal injury in diabetic nephropathy (2024-10-24)
期刊：MedComm
DOI：10.1002/mco2.742
影响因子 ：10.7
引用产品： HK-2 细胞
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Fullerenols as efficient ferroptosis inhibitor by targeting lipid peroxidation for preventing drug-induced acute kidney injury (2024-11-03)
期刊：JOURNAL OF COLLOID AND INTERFACE SCIENCE
DOI：10.1016/j.jcis.2024.10.198
影响因子 ：9.4
引用产品： HK-2 细胞
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STING contributes to lipopolysaccharide-induced tubular cell inflammation and pyroptosis by activating endoplasmic reticulum stress in acute kidney injury (2024-03-14)
期刊：Cell Death & Disease
DOI：10.1038/s41419-024-06600-1
影响因子 ：8.1
引用产品： HK-2 细胞
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Artesunate-Nanoliposome-TPP, a Novel Drug Delivery System That Targets the Mitochondria, Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Stress and Inflammatory Effects (2024-02-11)
期刊：International Journal of Nanomedicine
影响因子 ：8.0
引用产品： HK-2 细胞
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ANKRD1 aggravates renal ischaemia‒reperfusion injury via promoting TRIM25-mediated ubiquitination of ACSL3 (2024-09-17)
期刊：Clinical and Translational Medicine
影响因子 ：7.9
引用产品： HK-2 细胞 , 293T [HEK-293T] 细胞
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Hyaluronic acid-functionalized MOFs for combined sunitinib and siRNA therapy in renal cell carcinoma (2024-11-06)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.137317
影响因子 ：7.7
引用产品： HK-2 细胞 , 786-O [786-0] 细胞
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Omega-3 polyunsaturated fatty acids protect against cisplatin-induced nephrotoxicity by activating the Nrf2 signaling pathway (2024-11-09)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.137457
影响因子 ：7.7
引用产品： MEM（含NEAA） 培养基 , HK-2 细胞 , 特级胎牛血清
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Effects and mechanisms of Polygonati Rhizoma polysaccharide on potassium oxonate and hypoxanthine-induced hyperuricemia in mice (2024-09-13)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.135550
影响因子 ：7.7
引用产品： HK-2 细胞
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Klotho exerts protection in chronic kidney disease associated with regulating inflammatory response and lipid metabolism (2024-04-07)
期刊：Cell and Bioscience
DOI：10.1186/s13578-024-01226-4
影响因子 ：7.5
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2-Dodecyl-6-Methoxycyclohexa-2, 5-Diene-1, 4-Dione isolated from Averrhoa carambola L. root inhibits high glucose-induced EMT in HK-2 cells through targeting the regulation of miR-21–5p/Smad7 signaling pathway (2024-02-17)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.116280
影响因子 ：7.5
引用产品： HK-2 细胞
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High CD133 expression in proximal tubular cells in diabetic kidney disease: good or bad? (2024-02-16)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-04950-0
影响因子 ：7.4
引用产品： HK-2 细胞 , NRK-53E 细胞
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The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury (2024-01-02)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04793-1
影响因子 ：7.4
引用产品： HK-2 细胞
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Urinary miR-185-5p is a biomarker of renal tubulointerstitial fibrosis in IgA nephropathy (2024-02-15)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2024.1326026
影响因子 ：7.3
引用产品： HK-2 细胞
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Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway (2024-05-09)
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.8227
影响因子 ：7.2
引用产品： 青霉素-链霉素溶液（双抗），100× , MEM 培养基 , 特级胎牛血清 , HK-2 细胞 , 0.25%胰蛋白酶溶液（含EDTA，溶于PBS）
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Deubiquitinating enzyme OTUD4 stabilizes RBM47 to induce ATF3 transcription: a novel mechanism underlying the restrained malignant properties of ccRCC cells (2024-03-30)
期刊：APOPTOSIS
DOI：10.1007/s10495-024-01953-6
影响因子 ：7.2
引用产品： HK-2 细胞 , Caki-1 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , SW839 细胞
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TRPA1 protects against contrast-induced renal tubular injury by preserving mitochondrial dynamics via the AMPK/DRP1 pathway (2024-09-13)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.09.012
影响因子 ：7.1
引用产品： HK-2 细胞
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Vaporization phosphorization-mediated synthesis of phosphorus-doped TiO2 nanocomposites for combined photodynamic and photothermal therapy of renal cell carcinoma (2024-04-09)
期刊：Journal of Materials Chemistry B
影响因子 ：7.0
引用产品： 青霉素-链霉素溶液（双抗），100× , HK-2 细胞 , 786-O [786-0] 细胞
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Precise Carrier-Free Pt(IV)-Nanobombs for Apoptosis/Ferroptosis Synergistic Tumor Therapy: A New Effective Method to Obtain Good Chemotherapy and Low Toxicity (2024-12-16)
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.4c02034
影响因子 ：6.8
引用产品： RPMI-1640 培养基 , DMEM高糖 培养基 , DMEM/F12 培养基 , MEM 培养基 , A2780 细胞 , MCF7 [MCF-7] 细胞 , Hep G2 细胞 , HCT 116 细胞 , HK-2 细胞 , 人脐静脉内皮细胞
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Combination of DMDD with Nanoparticles Effective Against Diabetic Kidney Disease in vitro (2024-11-23)
期刊：International Journal of Nanomedicine
影响因子 ：6.6
引用产品： HK-2 细胞
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PARVB deficiency alleviates cisplatin-induced tubular injury by inhibiting TAK1 signaling (2024-09-05)
期刊：CELLULAR AND MOLECULAR LIFE SCIENCES
DOI：10.1007/s00018-024-05422-w
影响因子 ：6.2
引用产品： HK-2 细胞
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Maintaining calcium homeostasis as a strategy to alleviate nephrotoxicity caused by evodiamine (2024-06-14)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116563
影响因子 ：6.2
引用产品： HK-2 细胞
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CLIP170 enhancing FOSL1 expression via attenuating ubiquitin-mediated degradation of β-catenin drives renal cell carcinoma progression (2024-11-28)
期刊：CELLULAR AND MOLECULAR LIFE SCIENCES
DOI：10.1007/s00018-024-05504-9
影响因子 ：6.2
引用产品： 786-O [786-0] 细胞 , Caki-1 细胞 , 769-P 细胞 , HK-2 细胞 , ACHN 细胞
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(+)-Catechin ameliorates diabetic nephropathy injury by inhibiting endoplasmic reticulum stress-related NLRP3-mediated inflammation (2024-04-25)
期刊：Food & Function
影响因子 ：6.1
引用产品： HK-2 细胞
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Astragaloside IV protects renal tubular epithelial cells against oxidative stress-induced injury by upregulating CPT1A-mediated HSD17B10 lysine succinylation in diabetic kidney disease (2024-07-22)
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.8298
影响因子 ：6.1
引用产品： 293T [HEK-293T] 细胞 , HK-2 细胞
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Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis (2024-03-14)
期刊：ACS Pharmacology & Translational Science
影响因子 ：6.0
引用产品： HK-2 细胞
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M6A RNA Methylation-Mediated TUG1 Stability Maintains Mitochondrial Homeostasis during Kidney Aging by Epigenetically Regulating PGC1-α Expression (2024-09-05)
期刊：ANTIOXIDANTS & REDOX SIGNALING
影响因子 ：5.9
引用产品： HK-2 细胞 , MEM（含NEAA） 培养基 , 青霉素-链霉素溶液（双抗），100×
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Investigating HMGB1 as a Potential Serum Biomarker for Early Diabetic Nephropathy Monitoring by Quantitative Proteomics (2024-01-08)
期刊：iScience
DOI：10.1016/j.isci.2024.108834
影响因子 ：5.8
引用产品： HK-2 细胞
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Disulfidptosis-associated LncRNA signature predicts prognosis and immune response in kidney renal clear cell carcinoma (2024-08-22)
期刊：Biology Direct
DOI：10.1186/s13062-024-00517-7
影响因子 ：5.7
引用产品： 786-O [786-0] 细胞 , Caki-1 细胞 , HK-2 细胞
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Andrias davidianus bone peptides alleviates hyperuricemia-induced kidney damage in vitro and in vivo (2024-05-27)
期刊：Food Science and Human Wellness
DOI：10.26599/FSHW.2022.9250157
影响因子 ：5.6
引用产品： HK-2 细胞
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Facile synthesis of MoS2@red phosphorus heterojunction for synergistically photodynamic and photothermal therapy of renal cell carcinoma (2024-06-12)
期刊：COLLOIDS AND SURFACES B-BIOINTERFACES
DOI：10.1016/j.colsurfb.2024.114031
影响因子 ：5.4
引用产品： 786-O [786-0] 细胞 , HK-2 细胞
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Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport (2024-03-04)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
引用产品： HK-2 细胞
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Inhibitory effect of Incarvillea diffusa Royle extract in the formation of calcium oxalate nephrolithiasis by regulating ROS-induced Nrf2/HO-1 pathway in rats (2024-01-23)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
引用产品： HK-2 细胞
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Sleeve gastrectomy links the attenuation of diabetic kidney disease to the inhibition of renal tubular ferroptosis through down-regulating TGF-β1/Smad3 signaling pathway (2024-03-21)
期刊：JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
DOI：10.1007/s40618-023-02267-1
影响因子 ：5.4
引用产品： HK-2 细胞
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HMGN1 down-regulation in the diabetic kidney attenuates tubular cells injury and protects against renal inflammation via suppressing MCP-1 and KIM-1 expression through TLR4 (2024-02-27)
期刊：JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
DOI：10.1007/s40618-023-02292-0
影响因子 ：5.4
引用产品： HK-2 细胞
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ALKBH5 insufficiency protects against ferroptosis-driven cisplatin-induced renal cytotoxicity (2024-11-18)
期刊：CELL BIOLOGY AND TOXICOLOGY
DOI：10.1007/s10565-024-09947-5
影响因子 ：5.3
引用产品： HK-2 细胞
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Plasma protein affinity, antioxidant, and anti-lung cancer properties of O-methylated flavonol rhamnazin (2024-07-02)
期刊：Arabian Journal of Chemistry
DOI：10.1016/j.arabjc.2024.105891
影响因子 ：5.3
引用产品： HK-2 细胞
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Spike lavender essential oil attenuates hyperuricemia and induced renal injury by modulating the TLR4/NF-κB/NLRP3 signalling pathway (2024-07-20)
期刊：Arabian Journal of Chemistry
DOI：10.1016/j.arabjc.2024.105897
影响因子 ：5.3
引用产品： HK-2 细胞
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DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk (2024-09-12)
期刊：Chinese Medicine
DOI：10.1186/s13020-024-00993-z
影响因子 ：5.3
引用产品： HK-2 细胞
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Dexmedetomidine inhibits ferroptosis and attenuates sepsis-induced acute kidney injury via activating the Nrf2/SLC7A11/FSP1/CoQ10 pathway (2024-11-24)
期刊：REDOX REPORT
DOI：10.1080/13510002.2024.2430929
影响因子 ：5.2
引用产品： HK-2细胞专用培养基 , HK-2 细胞
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Disulfideptosis-associated lncRNAs reveal features of prognostic, immune escape, tumor mutation, and tumor malignant progression in renal clear cell carcinoma (2024-02-08)
期刊：Aging-US
影响因子 ：5.2
引用产品： 786-O [786-0] 细胞 , OS-RC-2 细胞 , A-498 细胞 , ACHN 细胞 , HK-2 细胞
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Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4 (2024-03-20)
期刊：CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 ：5.1
引用产品： HK-2 细胞
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Arylacryl amides: Design, synthesis and the protection against cisplatin-induced acute kidney injury via TLR4/STING/NF-κB pathway (2024-03-21)
期刊：BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2024.107303
影响因子 ：5.1
引用产品： HK-2 细胞
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The copper transporter, SLC31A1, transcriptionally activated by ELF3, imbalances copper homeostasis to exacerbate cisplatin-induced acute kidney injury through mitochondrial dysfunction (2024-03-09)
期刊：CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 ：5.1
引用产品： HK-2 细胞
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An aldose reductase inhibitor, WJ-39, ameliorates renal tubular injury in diabetic nephropathy by activating PINK1/Parkin signaling (2024-02-08)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2024.176376
影响因子 ：5.0
引用产品： HK-2 细胞
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Fasudil attenuates oxidative stress-induced partial epithelial-mesenchymal transition of tubular epithelial cells in hyperuricemic nephropathy via activating Nrf2 (2024-05-13)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2024.176640
影响因子 ：5.0
引用产品： HK-2 细胞
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Up-regulation of long non-coding RNA H19 ameliorates renal tubulointerstitial fibrosis by reducing lipid deposition and inflammatory response through regulation of the microRNA-130a-3p/long-chain acyl-CoA synthetase 1 axis (2024-05-09)
期刊：Non-coding RNA Research
DOI：10.1016/j.ncrna.2024.05.002
影响因子 ：5.0
引用产品： HK-2 细胞 , 293T [HEK-293T] 细胞
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Protective Effects of Dioscin and Diosgenin on Plateau Hyperuricemia by Attenuating Renal Inflammation via EPHX2 (2024-12-13)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：4.9
引用产品： HK-2 细胞 , 青霉素-链霉素溶液（双抗），100×
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BMAL1 alleviates sepsis-induced AKI by inhibiting ferroptosis (2024-09-19)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.113159
影响因子 ：4.8
引用产品： HK-2 细胞
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PER3 promoter hypermethylation correlates to the progression of pan-cancer (2024-10-14)
期刊：Clinical Epigenetics
DOI：10.1186/s13148-024-01760-5
影响因子 ：4.8
引用产品： Caki-2 细胞 , HK-2 细胞 , 786-O [786-0] 细胞 , McCoy's 5A 培养基 , RPMI-1640 培养基 , A549 [A-549] 细胞 , 青霉素-链霉素溶液（双抗），100×
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NDUFS3 alleviates oxidative stress and ferroptosis in sepsis induced acute kidney injury through AMPK pathway (2024-10-18)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.113393
影响因子 ：4.8
引用产品： HK-2 细胞 , 青霉素-链霉素溶液（双抗），100× , 特级胎牛血清
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TMEM16A inhibits renal tubulointerstitial fibrosis via Wnt/β-catenin signaling during hypertension nephropathy (2024-02-03)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2024.111088
影响因子 ：4.8
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Chlorogenic acid alleviate kidney fibrosis through regulating TLR4/NF-қB mediated oxidative stress and inflammation (2024-08-12)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：4.8
引用产品： HK-2 细胞
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Bergapten attenuates hemorrhagic shock induced multi-organ injury by inhibiting NLRP3 inflammasome activation and pyroptosis (2024-08-09)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112839
影响因子 ：4.8
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The STING antagonist SN-011 ameliorates cisplatin induced acute kidney injury via suppression of STING/NF-κB-mediated inflammation (2024-12-21)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.113876
影响因子 ：4.8
引用产品： HK-2 细胞
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Differential mechanisms of Liuwei Dihuang pill-derived formulas in treating diabetic nephropathy based on in vitro experiments and transcriptomic analysis (2024-12-19)
期刊：Food Bioscience
DOI：10.1016/j.fbio.2024.105732
影响因子 ：4.8
引用产品： HK-2 细胞
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A new strategy for Astragaloside IV in the treatment of diabetic kidney disease: Analyzing the regulation of ferroptosis and mitochondrial function of renal tubular epithelial cells (2024-08-12)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112794
影响因子 ：4.8
引用产品： HK-2 细胞
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Network pharmacology combined with transcriptomics reveals that formononetin, a biologically component of Astragalus membranaceus (Fisch.) Bunge, inhibits the PI3K/Akt signaling pathway to improve chronic renal failure (2024-11-06)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：4.8
引用产品： HK-2 细胞
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Proteomic and lipidomic analysis of the mechanism underlying astragaloside IV in mitigating ferroptosis through hypoxia-inducible factor 1α/heme oxygenase 1 pathway in renal tubular epithelial cells in diabetic kidney disease (2024-07-05)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：4.8
引用产品： HK-2 细胞
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Huangqi-Danshen Decoction Against Renal Fibrosis in UUO Mice via TGF-β1 Induced Downstream Signaling Pathway (2024-09-14)
期刊：Drug Design Development and Therapy
影响因子 ：4.7
引用产品： HK-2 细胞
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Low ACADM expression predicts poor prognosis and suppressive tumor microenvironment in clear cell renal cell carcinoma (2024-04-25)
期刊：Scientific Reports
DOI：10.1038/s41598-024-59746-5
影响因子 ：4.6
引用产品： RPMI-1640 培养基 , 786-O [786-0] 细胞 , ACHN 细胞 , 769-P 细胞 , HK-2 细胞 , Caki-1 细胞 , McCoy's 5A 培养基 , MEM（含NEAA） 培养基
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Hazel Leaf Polyphenol Extract Alleviated Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis through Inhibiting Hippo Signaling (2024-04-11)
期刊：MOLECULES
影响因子 ：4.6
引用产品： HK-2 细胞 , 特级胎牛血清 , 青霉素-链霉素溶液（双抗），100× , MEM 培养基
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Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis (2024-03-20)
期刊：Scientific Reports
DOI：10.1038/s41598-024-56950-1
影响因子 ：4.6
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Qi-dan-dihuang decoction ameliorates renal fibrosis in diabetic rats via p38MAPK/AKT/mTOR signaling pathway (2024-03-08)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.5
引用产品： HK-2 细胞 , NRK-52E 细胞
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Non-Canonical STING-PERK Pathway Modulation of Cellular Senescence and Therapeutic Response in Sepsis-Associated Acute Kidney Injury (2024-06-24)
期刊：INFLAMMATION
DOI：10.1007/s10753-024-02081-8
影响因子 ：4.5
引用产品： HK-2 细胞
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HIF-1α induced FGF18 alleviates renal ischemia/reperfusion injury via YAP (2024-10-07)
期刊：FASEB JOURNAL
影响因子 ：4.4
引用产品： HK-2 细胞
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ESRRA modulation by empagliflozin mitigates diabetic tubular injury via mitochondrial restoration (2024-07-24)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2024.111308
影响因子 ：4.4
引用产品： HK-2 细胞
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Astragaloside IV Attenuates Renal Tubule Injury in DKD rats via Suppression of CD36-mediated NLRP3 Inflammasome Activation (2024-03-01)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2024.1285797
影响因子 ：4.4
引用产品： HK-2 细胞
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Colquhounia root tablet improves diabetic kidney disease by regulating epithelial-mesenchymal transition via the PTEN/PI3K/AKT pathway (2024-07-26)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2024.1418588
影响因子 ：4.4
引用产品： HK-2 细胞
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Crosstalk of disulfidptosis-related subtypes identifying a prognostic signature to improve prognosis and immunotherapy responses of clear cell renal cell carcinoma patients (2024-04-26)
期刊：BMC GENOMICS
DOI：10.1186/s12864-024-10307-0
影响因子 ：4.4
引用产品： Caki-1 细胞 , 786-O [786-0] 细胞 , HK-2 细胞 , ACHN 细胞
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Tetrahydrocurcumin Attenuates Polymyxin B Sulfate-Induced HK-2 Cells Apoptosis by Inhibiting Endoplasmic Reticulum Stress-Mediated PERK/eIF2α/ATF4/CHOP Signaling Pathway Axis (2024-07-18)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.4
引用产品： HK-2 细胞 , MEM（含NEAA） 培养基 , 青霉素-链霉素溶液（双抗），100× , 特级胎牛血清
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miR-664a-5p promotes experimental membranous nephropathy progression through HIPK2/Calpain1/GSα-mediated autophagy inhibition (2024-01-07)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：4.3
引用产品： HK-2 细胞 , 人肾足突细胞 , 293T [HEK-293T] 细胞 , MEM（含NEAA） 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液（双抗），100× , RPMI-1640 培养基 , Interferon γ/IFN-γ/IFNG, Human, Recombinant , DMEM高糖 培养基
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Improved Immunotherapy Outcomes via Cuproptosis Upregulation of HLA-DRA Expression: Promoting the Aggregation of CD4+ and CD8+T Lymphocytes in Clear Cell Renal Cell Carcinoma (2024-05-24)
期刊：Pharmaceuticals
影响因子 ：4.3
引用产品： 786-O [786-0] 细胞 , OS-RC-2 细胞 , A-498 细胞 , HK-2 细胞 , Renca [RenCa] 细胞
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The PP2A Inhibitor LB-100 Mitigates Lupus Nephritis by Suppressing Tertiary Lymphoid Structure Formation (2024-06-03)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2024.176703
影响因子 ：4.2
引用产品： HK-2 细胞
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Gingipain and oncostatin M synergistically disrupt kidney tight junctions in periodontitis-associated acute kidney injury (2024-07-04)
期刊：JOURNAL OF PERIODONTOLOGY
影响因子 ：4.2
引用产品： HK-2 细胞
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CITED2 Mediates Metabolic Reprogramming in Renal Tubular Epithelial Cells via the AKT Signaling Pathway to Induce Sepsis-Associated Acute Kidney Injury (2024-11-22)
期刊：Journal of Inflammation Research
影响因子 ：4.2
引用产品： HK-2 细胞
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Non-small Nanoprobes Based on FDA-approval Formulation for NIR-II Imaging and Detection of Drug-induced Acute Kidney Injury (2024-12-13)
期刊：DYES AND PIGMENTS
DOI：10.1016/j.dyepig.2024.112598
影响因子 ：4.1
引用产品： HK-2 细胞
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Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways (2024-02-08)
期刊：INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI：10.1016/j.biocel.2024.106549
影响因子 ：4.0
引用产品： HK-2 细胞
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Modified Zhenwu Tang Delays Chronic Renal Failure Progression by Modulating Oxidative Stress and Hypoxic Responses in Renal Proximal Tubular Epithelial Cells (2024-05-15)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e31265
影响因子 ：4.0
引用产品： HK-2 细胞
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Deficiency of lysophosphatidic acid receptor 3 decreases erythropoietin production in hypoxic mouse kidneys (2024-11-18)
期刊：Lipids in Health and Disease
DOI：10.1186/s12944-024-02367-8
影响因子 ：3.9
引用产品： MEM（含NEAA） 培养基 , HK-2 细胞
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A low-toxicity uranyl-selective-binding linear pentapeptide sequence as a potential uranium decorporation agent (2024-12-10)
期刊：RSC Advances
影响因子 ：3.9
引用产品： HK-2 细胞 , 特级胎牛血清 , DMEM/F12 培养基
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Disruption of Autophagic Flux and Treatment with the PDPK1 Inhibitor GSK2334470 Synergistically Inhibit Renal Cell Carcinoma Pathogenesis (2024-01-20)
期刊：Journal of Cancer
影响因子 ：3.9
引用产品： 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞
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Acyl-CoA thioesterase 13 (ACOT13) attenuates the progression of autosomal dominant polycystic kidney disease in vitro via triggering mitochondrial-related cell apoptosis (2024-08-21)
期刊：Aging-US
影响因子 ：3.9
引用产品： HK-2 细胞 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液（双抗），100×
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SLC11A1 promotes kidney renal clear cell carcinoma (KIRC) progression by remodeling the tumor microenvironment (2024-05-16)
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2024.116975
影响因子 ：3.8
引用产品： 786-O [786-0] 细胞 , SW839 细胞 , A-498 细胞 , HK-2 细胞 , OS-RC-2 细胞 , THP-1 细胞
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Lumbrokinase (LK) ameliorates diabetic kidney disease renal fibrosis through regulating snail via m6A RNA methyltransferase 3 (2024-11-19)
期刊：Scientific Reports
DOI：10.1038/s41598-024-80168-w
影响因子 ：3.8
引用产品： MEM（含NEAA） 培养基 , HK-2 细胞
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Oxalate-upregulated annexin A6 promotes the formation of calcium oxalate kidney stones by exacerbating calcium release-mediated oxidative stress injury in renal tubular epithelial cells and crystal-cell adhesion (2024-10-25)
期刊：ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影响因子 ：3.8
引用产品： HK-2 细胞
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Novel Glycyrrhetin Ureas Possessing 2-Hydroxy-3-enone A Ring: Modification, Anti-inflammatory Activity, and Targeted STING for the Remedy of Acute Kidney Injury (2024-11-27)
期刊：ACS Omega
影响因子 ：3.7
引用产品： HK-2 细胞
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Excess iron accumulation mediated senescence in diabetic kidney injury (2024-03-14)
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 ：3.6
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The Involvement of Endoplasmic Reticulum Stress during the Interaction between Calcium Oxalate Crystals and Renal Tubular Epithelial Cells (2024-09-27)
期刊：Biology-Basel
影响因子 ：3.6
引用产品： HK-2 细胞
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Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC (2024-03-21)
期刊：GENE
DOI：10.1016/j.gene.2024.148403
影响因子 ：3.5
引用产品： HK-2 细胞 , ACHN 细胞 , A-498 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , Caki-1 细胞 , RPMI-1640 培养基 , MEM 培养基
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Astragaloside IV Protects against Diabetic Nephropathy by Inhibiting FUNDC1-Dependent Mitochondria-Associated Endoplasmic Reticulum Membranes (2024-08-30)
期刊：JOURNAL OF FOOD BIOCHEMISTRY
影响因子 ：3.5
引用产品： HK-2 细胞
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ZBP1 as a prognostic biomarker correlated with cell proliferation in clear cell renal cell carcinoma (2024-10-10)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e39267
影响因子 ：3.4
引用产品： 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞 , ACHN 细胞 , 769-P 细胞
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Megalin-targeted acetylcysteine polymeric prodrug ameliorates ischemia-reperfusion-induced acute kidney injury (2024-05-08)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e30947
影响因子 ：3.4
引用产品： HK-2 细胞
-
Comprehensive molecular analyses and experimental validation of CDCAs with potential implications in kidney renal papillary cell carcinoma prognosis (2024-06-14)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e33045
影响因子 ：3.4
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Myricetin alleviates renal tubular Epithelial-Mesenchymal Transition via NOX4/NF-κB/Snail axis in diabetic nephropathy based on network pharmacology analysis (2024-07-27)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e35234
影响因子 ：3.4
引用产品： HK-2 细胞
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DLX5 Promotes Radioresistance in Renal Cell Carcinoma by Upregulating c-Myc Expression (2024-11-26)
期刊：Frontiers in Bioscience-Landmark
影响因子 ：3.3
引用产品： 特级胎牛血清 , McCoy's 5A 培养基 , A-498 细胞 , MEM（含NEAA） 培养基 , 786-O [786-0] 细胞 , 青霉素-链霉素溶液（双抗），100× , Caki-1 细胞 , RPMI-1640 培养基 , HK-2 细胞
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Carnosol alleviates cisplatin–induced acute kidney injury by regulating apoptosis and pyroptosis (2024-11-10)
期刊：CELL BIOLOGY INTERNATIONAL
影响因子 ：3.3
引用产品： HK-2 细胞 , MEM（含NEAA） 培养基
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A Model to Predict Prognosis of Renal Cell Clear Cell Carcinoma Based on 3 Angiogenesis-related Long Non-coding RNAs (2024-04-29)
期刊：Journal of Cancer
影响因子 ：3.3
引用产品： HK-2 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞 , RCC-JF 细胞
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Andrographolide attenuates sepsis-induced acute kidney injury by inhibiting ferroptosis through the Nrf2/FSP1 pathway. (2024-03-12)
期刊：FREE RADICAL RESEARCH
DOI：10.1080/10715762.2024.2330413
影响因子 ：3.3
引用产品： HK-2 细胞
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Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma (2024-11-29)
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2024.117181
影响因子 ：3.3
引用产品： Caki-1 细胞 , 786-O [786-0] 细胞 , Caki-2 细胞 , HK-2 细胞 , 769-P 细胞
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Knockdown of Leucine-rich alpha-2-glycoprotein 1 alleviates renal ischemia-reperfusion injury by inhibiting NOX4-mediated apoptosis, inflammation, and oxidative stress (2024-11-19)
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2024.114341
影响因子 ：3.3
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Exploring necrosis-associated mitochondrial gene signatures: revealing their role in prognosis and immunotherapy of renal clear cell carcinoma (2024-07-18)
期刊：CLINICAL AND EXPERIMENTAL MEDICINE
DOI：10.1007/s10238-024-01426-9
影响因子 ：3.2
引用产品： 786-O [786-0] 细胞 , OS-RC-2 细胞 , ACHN 细胞 , Caki-1 细胞 , HK-2 细胞
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STUB1 exacerbates calcium oxalate-induced kidney injury by modulating reactive oxygen species-mediated cellular autophagy via regulating CFTR ubiquitination (2024-04-02)
期刊：Urolithiasis
DOI：10.1007/s00240-024-01547-6
影响因子 ：3.1
引用产品： HK-2 细胞
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CircACTR2 attenuated the effects of tetramethylpyrazine on human kidney cell injury (2024-03-01)
期刊：JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
DOI：10.1007/s10863-024-10001-6
影响因子 ：3.0
引用产品： HK-2 细胞
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Reserpine alleviates cisplatin-induced acute kidney injury via anti-ferroptosis and cGAS/STING pathway (2024-10-08)
期刊：RENAL FAILURE
DOI：10.1080/0886022X.2024.2406395
影响因子 ：3.0
引用产品： HK-2 细胞 , HT-1080 [HT1080] 细胞 , Caov-3 细胞
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DKK3 promotes renal fibrosis by increasing MFF-mediated mitochondrial dysfunction in Wnt/β-catenin pathway-dependent manner (2024-04-29)
期刊：RENAL FAILURE
DOI：10.1080/0886022X.2024.2343817
影响因子 ：3.0
引用产品： HK-2 细胞
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FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent manner (2024-03-06)
期刊：RENAL FAILURE
DOI：10.1080/0886022X.2024.2322037
影响因子 ：3.0
引用产品： HK-2 细胞 , MEM (含NEAA) 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100× , Hank's平衡盐溶液 (HBSS)，含钙、镁，不含酚红
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WTAP-mediated N6-methyladenosine modification promotes the inflammation, mitochondrial damage and ferroptosis of kidney tubular epithelial cells in acute kidney injury by regulating LMNB1 expression and activating NF-κB and JAK2/STAT3 pathways (2024-03-22)
期刊：JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
DOI：10.1007/s10863-024-10015-0
影响因子 ：3.0
引用产品： HK-2 细胞 , 青霉素-链霉素溶液 (双抗)，100×
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Decreased expression of TXNIP is associated with poor prognosis and immune infiltration in kidney renal clear cell carcinoma (2024-01-12)
期刊：Oncology Letters
影响因子 ：2.9
-
MicroRNA-668 alleviates renal fibrosis through PPARα/PGC-1α pathway (2024-12-28)
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-024-02248-x
影响因子 ：2.8
引用产品： HK-2 细胞
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Clinical Significance of Apela in Acute Cardiorenal Insuffiency of Chronic Heart Failure (2024-01-18)
期刊：KIDNEY & BLOOD PRESSURE RESEARCH
影响因子 ：2.8
引用产品： THP-1 细胞 , 人肾小球内皮细胞 , 人肾小球系膜细胞 , HK-2 细胞 , DMEM高糖 培养基 , 人肾小球内皮细胞完全培养基 , 人肾小球系膜细胞完全培养基 , 人肾小管上皮细胞完全培养基
-
CircVMA21-related pathway alleviates lipopolysaccharide-induced HK-2 cell injury (2024-03-25)
期刊：SHOCK
DOI：10.1097/SHK.0000000000002364
影响因子 ：2.7
引用产品： HK-2 细胞 , HK-2细胞专用培养基 , 293T [HEK-293T] 细胞
-
Curcumin-induced exosomal FTO from bone marrow stem cells alleviates sepsis-associated acute kidney injury by modulating the m6A methylation of OXSR1 (2024-12-30)
期刊：KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
影响因子 ：2.7
引用产品： 人骨髓间充质干细胞 , 人骨髓间充质干细胞完全培养基 , HK-2 细胞
-
Molecular mechanism of ALKBH5-mediated m6A demethylation regulating lipopolysaccharide-induced epithelial–mesenchymal transition in sepsis-induced acute kidney injury (2024-09-17)
期刊：KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
影响因子 ：2.7
引用产品： HK-2 细胞 , DMEM高糖 培养基
-
ETS homologous factor, controlled by lysine-specific demethylase 5B, suppresses clear cell renal cell carcinoma by inducing Filamin-B (2024-06-14)
期刊：GENE
DOI：10.1016/j.gene.2024.148702
影响因子 ：2.6
引用产品： OS-RC-2 细胞 , Caki-1 细胞 , HK-2 细胞 , THP-1 细胞
-
Comprehensive Pan-Cancer Analysis of Connexin 43 as a Potential Biomarker and Therapeutic Target in Human Kidney Renal Clear Cell Carcinoma (KIRC) (2024-05-08)
期刊：Medicina-Lithuania
影响因子 ：2.6
引用产品： ACHN 细胞 , OS-RC-2 细胞 , HK-2 细胞 , 786-O [786-0] 细胞
-
UNC13B regulates the sensitivity of Wilms' tumor cells to doxorubicin by modulating lysosomes (2024-07-22)
期刊：Oncology Letters
影响因子 ：2.5
引用产品： STR鉴定 , 293T [HEK-293T] 细胞 , HK-2 细胞
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Isoquercitrin improves diabetes nephropathy by inhibiting the sodium-glucose co-transporter-2 pathway (2024-12-06)
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2024.151142
影响因子 ：2.5
引用产品： HK-2 细胞 , MEM（含NEAA） 培养基
-
WIP1-mediated regulation of p38 MAPK signaling attenuates pyroptosis in sepsis-associated acute kidney injury (2024-06-26)
期刊：IMMUNOBIOLOGY
DOI：10.1016/j.imbio.2024.152832
影响因子 ：2.5
引用产品： HK-2 细胞
-
Fortunellin attenuates sepsis-induced acute kidney injury by inhibiting inflammation and ferroptosis via the TLR4/NF-κB pathway (2024-10-30)
期刊：HISTOLOGY AND HISTOPATHOLOGY
影响因子 ：2.5
引用产品： HK-2 细胞
-
ALKBH5-Mediated m6A Modification Drives Apoptosis in Renal Tubular Epithelial Cells by Negatively Regulating MUC1 (2024-08-22)
期刊：MOLECULAR BIOTECHNOLOGY
DOI：10.1007/s12033-024-01250-2
影响因子 ：2.4
引用产品： HK-2 细胞
-
RUNX3 alleviates mitochondrial dysfunction and tubular damage by inhibiting TLR4/NF-κB signalling pathway in diabetic kidney disease (2024-05-12)
期刊：NEPHROLOGY
影响因子 ：2.4
引用产品： HK-2 细胞
-
METTL3 and IGF2BP1-mediated m6A modification of ZHX2 promotes tumor property of renal cell carcinoma (2024-08-19)
期刊：KIDNEY & BLOOD PRESSURE RESEARCH
影响因子 ：2.3
引用产品： RPMI-1640 完全培养基（含10% FBS） , 786-O [786-0] 细胞 , OS-RC-2 细胞 , HK-2 细胞 , 特级胎牛血清 , MEM（含NEAA） 培养基 , ACHN 细胞
-
Knockdown of circ-Gatad1 alleviates LPS induced HK2 cell injury via targeting miR-22-3p/TRPM7 axis in septic acute kidney (2024-03-05)
期刊：BMC Nephrology
DOI：10.1186/s12882-024-03513-1
影响因子 ：2.3
引用产品： HK-2 细胞 , MEM 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100×
-
Cytosolic mtDNA–cGAS–STING axis contributes to sepsis-induced acute kidney injury via activating the NLRP3 inflammasome (2024-01-19)
期刊：Clinical and Experimental Nephrology
DOI：10.1007/s10157-023-02448-5
影响因子 ：2.3
引用产品： HK-2 细胞 , HK-2细胞专用培养基
-
Cell division cycle 42 attenuates high glucose-treated renal tubular epithelial cell apoptosis, fibrosis, and inflammation, but activates the PAK1/AKT pathway (2024-02-28)
期刊：Clinical and Experimental Nephrology
DOI：10.1007/s10157-024-02468-9
影响因子 ：2.3
引用产品： HK-2 细胞 , DMEM/F12 培养基 , 青霉素-链霉素溶液 (双抗)，100×
-
MicroR-380-3p Reduces Sepsis-Induced Acute Kidney Injury via Regulating RAB1P to Restrain NF-κB Pathway (2024-05-31)
期刊：TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
影响因子 ：2.2
引用产品： HK-2 细胞
-
Integration of bulk RNA-seq and single-cell RNA-seq constructs: a cancer-associated fibroblasts-related signature to predict prognosis and therapeutic response in clear cell renal cell carcinoma. (2024-04-15)
期刊：American Journal of Translational Research
影响因子 ：2.2
引用产品： HK-2 细胞 , A-498 细胞 , 786-O [786-0] 细胞
-
Integrative bioinformatics and in vitro exploration of EVI2A expression: unraveling its immunological and prognostic implications in kidney renal clear cell carcinoma (2024-10-16)
期刊：ONCOLOGY RESEARCH
影响因子 ：2.0
引用产品： Caki-1 细胞 , OS-RC-2 细胞 , ACHN 细胞 , HK-2 细胞 , 786-O [786-0] 细胞
-
Plasma exosomes may mediate the development of lupus nephritis in patients with systemic lupus erythematosus (2024-10-31)
期刊：LUPUS
影响因子 ：1.9
引用产品： HK-2细胞专用培养基 , HK-2 细胞
-
Quercetin Attenuates Acute Kidney Injury Caused by Cisplatin by Inhibiting Ferroptosis and Cuproptosis (2024-07-18)
期刊：CELL BIOCHEMISTRY AND BIOPHYSICS
DOI：10.1007/s12013-024-01379-6
影响因子 ：1.8
引用产品： HK-2 细胞
-
Ethanol extract of Abelmoschus manihot suppresses endoplasmic reticulum stress in contrast-induced nephropathy (2024-01-23)
期刊：Asian Pacific Journal of Tropical Biomedicine
影响因子 ：1.7
-
Astragaloside IV Inhibits the Pyroptosis in the Acute Kidney Injury through Targeting the SIRT1/FOXO3a Axis (2024-10-30)
期刊：CHEMICAL & PHARMACEUTICAL BULLETIN
影响因子 ：1.5
引用产品： 青霉素-链霉素溶液（双抗），100× , DMEM/F12 培养基 , HK-2 细胞 , 特级胎牛血清
-
CircSCNN1A inhibits the proliferation, migration and invasion of renal cell carcinoma cells by decreasing CLDN8 expression through miR-590-5p (2024-05-19)
期刊：GENESIS
影响因子 ：1.5
引用产品： 786-O [786-0] 细胞 , McCoy's 5A 培养基 , DMEM高糖 培养基 , A-498 细胞 , HK-2 细胞 , RPMI-1640 培养基 , 769-P 细胞 , Caki-1 细胞
-
Hypoxia-triggered tumor specific glutamine inhibition for reversing cisplatin resistance of chemotherapy (2023-11-27)
期刊：CHEMICAL ENGINEERING JOURNAL
影响因子 ：15.1
引用产品： A549 [A-549] 细胞 , A549/DDP 细胞 , 青霉素-链霉素溶液 (双抗)，100× , HK-2 细胞
-
Self-oriented ferritin nanocages mitigate iron overload-induced oxidative stress for acute kidney injury (2023-05-02)
期刊：CHEMICAL ENGINEERING JOURNAL
影响因子 ：15.1
引用产品： HK-2 细胞
-
Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition (2023-08-02)
期刊：Science Advances
影响因子 ：13.6
引用产品： HK-2 细胞
-
Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI (2023-03-21)
期刊：Theranostics
影响因子 ：12.4
引用产品： HK-2 细胞
-
Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2-dependent mechanism (2023-08-03)
期刊：Clinical and Translational Medicine
影响因子 ：10.6
引用产品： HK-2 细胞
-
Renal clearance of graphene oxide: glomerular filtration or tubular secretion and selective kidney injury association with its lateral dimension (2023-02-10)
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-023-01781-x
影响因子 ：10.2
引用产品： HK-2 细胞
-
Liraglutide abrogates nephrotoxic effects of chemotherapies (2023-02-04)
期刊：PHARMACOLOGICAL RESEARCH
DOI：10.1016/j.phrs.2023.106680
影响因子 ：9.3
引用产品： HK-2 细胞
-
Aldehyde dehydrogenase 2 alleviates mitochondrial dysfunction by promoting PGC-1α-mediated biogenesis in acute kidney injury (2023-01-20)
期刊：Cell Death & Disease
DOI：10.1038/s41419-023-05557-x
影响因子 ：9.0
引用产品： HK-2 细胞
-
circWSB1 promotes tumor progression in ccRCC via circWSB1/miR-182-5p/WSB1 axis (2023-11-24)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2023.128338
影响因子 ：8.2
引用产品： HK-2 细胞
-
Inhibition of intrarenal PRR-RAS pathway by Ganoderma lucidum polysaccharide peptides in proteinuric nephropathy (2023-10-16)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2023.127336
影响因子 ：8.2
引用产品： HK-2 细胞 , HK-2细胞专用培养基
-
Nephroprotective Effects of Selenium Nanoparticles Against Sodium Arsenite-Induced Damages (2023-06-12)
期刊：International Journal of Nanomedicine
影响因子 ：8.0
引用产品： HK-2 细胞
-
Celastrol alleviated acute kidney injury by inhibition of ferroptosis through Nrf2/GPX4 pathway (2023-08-18)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2023.115333
影响因子 ：7.5
引用产品： MEM (含NEAA) 培养基 , 青霉素-链霉素溶液 (双抗)，100× , 特级胎牛血清 , HK-2 细胞
-
Jiedu Tongluo Baoshen formula enhances renal tubular epithelial cell autophagy to prevent renal fibrosis by activating SIRT1/LKB1/AMPK pathway (2023-02-03)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2023.114340
影响因子 ：7.5
引用产品： NRK-52E 细胞 , HK-2 细胞
-
Inhibition of ACSF2 protects against renal ischemia/reperfusion injury via mediating mitophagy in proximal tubular cells (2023-02-09)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2023.02.003
影响因子 ：7.4
引用产品： HK-2 细胞
-
TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage (2023-10-05)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04351-9
影响因子 ：7.4
引用产品： HK-2 细胞 , MEM (含NEAA) 培养基
-
Knockdown of NR3C1 inhibits the proliferation and migration of clear cell renal cell carcinoma through activating endoplasmic reticulum stress–mitophagy (2023-10-08)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04560-2
影响因子 ：7.4
引用产品： HK-2 细胞
-
Bioinformatics analysis reveals the potential role of matrix metalloproteinases in immunity and urolithiasis (2023-03-15)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2023.1158379
影响因子 ：7.3
引用产品： HK-2 细胞
-
Prognostic and tumor microenvironmental feature of clear cell renal cell carcinoma revealed by m6A and lactylation modification-related genes (2023-08-11)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2023.1225023
影响因子 ：7.3
-
Discovery and Design of Novel Cyclic Peptides as Specific Inhibitors Targeting CCN2 and Disrupting CCN2/EGFR Interaction for Kidney Fibrosis Treatment (2023-06-06)
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c00594
影响因子 ：7.3
引用产品： HK-2 细胞
-
Hyperoside mediates protection from diabetes kidney disease by regulating ROS-ERK signaling pathway and pyroptosis (2023-08-30)
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.7993
影响因子 ：7.2
引用产品： HK-2 细胞
-
Hederasaponin C inhibits LPS-induced acute kidney injury in mice by targeting TLR4 and regulating the PIP2/NF-κB/NLRP3 signaling pathway (2023-10-01)
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.8014
影响因子 ：7.2
引用产品： HK-2 细胞
-
Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway (2023-07-25)
期刊：Cell Death Discovery
DOI：10.1038/s41420-023-01564-1
影响因子 ：7.0
引用产品： HK-2 细胞
-
Seratrodast platinum(IV) hybrids efficiently inhibit cancer-related thrombosis and metastasis phenotype in vitro and in vivo (2023-09-18)
期刊：Inorganic Chemistry Frontiers
影响因子 ：7.0
引用产品： A549 [A-549] 细胞 , A2780 细胞 , Hep G2 细胞 , AsPC-1 细胞 , HCT 116 细胞 , HK-2 细胞
-
Human bone marrow mesenchymal stem cell-derived extracellular vesicles reduce inflammation and pyroptosis in acute kidney injury via miR-223-3p/HDAC2/SNRK (2023-01-14)
期刊：INFLAMMATION RESEARCH
DOI：10.1007/s00011-022-01653-4
影响因子 ：6.7
-
Systemic mutation of Ncf1 ameliorates obstruction-induced renal fibrosis while macrophage-rescued NCF1 further alleviates renal fibrosis (2023-06-30)
期刊：ANTIOXIDANTS & REDOX SIGNALING
影响因子 ：6.6
引用产品： HK-2 细胞
-
Novel Role of Hemeoxygenase-1 in Phthalate-Induced Renal Proximal Tubule Cell Ferroptosis (2023-01-25)
期刊：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 ：6.1
引用产品： HK-2 细胞 , MEM (含NEAA) 培养基
-
Ochratoxin A Induces Renal Cell Ferroptosis by Disrupting Iron Homeostasis and Increasing ROS (2023-12-22)
期刊：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 ：6.1
引用产品： HK-2 细胞 , 青霉素-链霉素溶液 (双抗)，100×
-
Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota (2023-01-17)
期刊：Food & Function
影响因子 ：6.1
引用产品： HK-2 细胞 , MEM (含NEAA) 培养基
-
Identification of the H3K36me3 reader LEDGF/p75 in the pancancer landscape and functional exploration in clear cell renal cell carcinoma (2023-08-26)
期刊：Computational and Structural Biotechnology Journal
DOI：10.1016/j.csbj.2023.08.023
影响因子 ：6.0
引用产品： Caki-1 细胞 , 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞
-
Gasdermin D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway (2023-11-14)
期刊：iScience
DOI：10.1016/j.isci.2023.108463
影响因子 ：5.8
引用产品： NRK-52E 细胞 , HK-2 细胞
-
Polystyrene nanoplastics induce apoptosis of human kidney proximal tubular epithelial cells via oxidative stress and MAPK signaling pathways (2023-10-04)
期刊：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
DOI：10.1007/s11356-023-30155-x
影响因子 ：5.8
引用产品： HK-2 细胞
-
CIRP attenuates acute kidney injury after hypothermic cardiovascular surgery by inhibiting PHD3/HIF-1α-mediated ROS-TGF-β1/p38 MAPK activation and mitochondrial apoptotic pathways (2023-05-01)
期刊：MOLECULAR MEDICINE
DOI：10.1186/s10020-023-00655-0
影响因子 ：5.7
引用产品： HK-2 细胞
-
Human Umbilical Cord Mesenchymal Stem Cells Protect against Renal Ischemia-Reperfusion Injury by Secreting Extracellular Vesicles Loaded with miR-148b-3p That Target Pyruvate Dehydrogenase Kinase 4 to Inhibit Endoplasmic Reticulum Stress at the Reperfusion Stages (2023-05-17)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.6
引用产品： HK-2 细胞
-
Exosome-mediated crosstalk between epithelial cells amplifies the cell injury cascade in CaOx stone formation (2023-02-28)
期刊：Journal of Biological Engineering
DOI：10.1186/s13036-023-00324-0
影响因子 ：5.6
引用产品： HK-2 细胞
-
LMCD1 is involved in tubulointerstitial inflammation in the early phase of renal fibrosis by promoting NFATc1-mediated NLRP3 activation (2023-06-11)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110362
影响因子 ：5.6
引用产品： HK-2 细胞
-
Melatonin alleviates intrarenal CaOx crystals deposition through inhibiting LPS-induced non-canonical inflammasome-mediated renal tubular epithelial cells pyroptosis (2023-08-24)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110796
影响因子 ：5.6
引用产品： HK-2 细胞 , HK-2细胞专用培养基
-
Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro (2023-01-26)
期刊：Frontiers in Endocrinology
DOI：10.3389/fendo.2022.1009507
影响因子 ：5.2
引用产品： HK-2 细胞
-
Jian-Pi-Yi-Shen formula alleviates renal fibrosis by restoring NAD+ biosynthesis in vivo and in vitro (2023-12-28)
期刊：Aging-US
影响因子 ：5.2
引用产品： HK-2 细胞
-
Establishing a prognostic model based on five starvation-related long non-coding RNAs for clear cell renal cell carcinoma (2023-06-20)
期刊：Aging-US
影响因子 ：5.2
引用产品： 786-O [786-0] 细胞 , Caki-1 细胞 , HK-2 细胞
-
Ferroptosis in calcium oxalate kidney stone formation and the possible regulatory mechanism of ANKRD1 (2023-03-11)
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
DOI：10.1016/j.bbamcr.2023.119452
影响因子 ：5.1
引用产品： HK-2 细胞 , HK-2细胞专用培养基
-
LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1–Induced Epithelial–Mesenchymal Transition in Human Kidney 2 Cells (2023-01-10)
期刊：LABORATORY INVESTIGATION
DOI：10.1016/j.labinv.2022.100016
影响因子 ：5.0
引用产品： HK-2 细胞
-
Identification of a novel 5-methylcytosine-related signature for prognostic prediction of kidney renal papillary cell carcinoma and a Putative target for drug repurposing (2023-07-29)
期刊：Translational Oncology
DOI：10.1016/j.tranon.2023.101741
影响因子 ：5.0
-
FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells (2023-09-02)
期刊：Journal of Translational Internal Medicine
影响因子 ：4.9
-
Glycyrrhizic acid improves tacrolimus-induced renal injury by regulating autophagy (2023-01-23)
期刊：FASEB JOURNAL
影响因子 ：4.8
引用产品： HK-2 细胞
-
Expression of gasdermin D in clear cell renal cell carcinoma and its effect on its biological function (2023-07-06)
期刊：Frontiers in Oncology
影响因子 ：4.7
引用产品： 786-O [786-0] 细胞 , 769-P 细胞 , HK-2 细胞
-
Tumor-associated M2 macrophages in the immune microenvironment influence the progression of renal clear cell carcinoma by regulating M2 macrophage-associated genes (2023-06-08)
期刊：Frontiers in Oncology
影响因子 ：4.7
引用产品： 786-O [786-0] 细胞 , HK-2 细胞 , THP-1 细胞 , 特级胎牛血清
-
A pan-cancer analysis of DDR1 in prognostic signature and tumor immunity, drug resistance (2023-04-08)
期刊：Scientific Reports
DOI：10.1038/s41598-023-27975-9
影响因子 ：4.6
引用产品： HK-2 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞 , SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞 , RWPE-1 细胞 , PC-3 细胞 , DU 145 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , Ham's F-12K 培养基 , 人前列腺上皮细胞完全培养基
-
Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis (2023-10-23)
期刊：Scientific Reports
DOI：10.1038/s41598-023-45188-y
影响因子 ：4.6
引用产品： HK-2 细胞 , NRK-49F 细胞 , 293T [HEK-293T] 细胞
-
Protease-Activated Receptor-2 and Phospholipid Metabolism Analysis in Hyperuricemia-Induced Renal Injury (2023-07-13)
期刊：MEDIATORS OF INFLAMMATION
影响因子 ：4.6
引用产品： HK-2 细胞
-
Ganoderic Acid A and Its Amide Derivatives as Potential Anti-Cancer Agents by Regulating the p53-MDM2 Pathway: Synthesis and Biological Evaluation (2023-03-04)
期刊：MOLECULES
影响因子 ：4.6
引用产品： MCF7 [MCF-7] 细胞 , Hep G2 细胞 , SJSA-1 细胞 , HK-2 细胞
-
Norcantharidin-Encapsulated C60-Modified Nanomicelles: A Potential Approach to Mitigate Cytotoxicity in Renal Cells and Simultaneously Enhance Anti-Tumor Activity in Hepatocellular Carcinoma Cells (2023-11-15)
期刊：MOLECULES
影响因子 ：4.6
引用产品： HK-2 细胞
-
Focusing on the Abnormal Events of NPC1, NPC2, and NPC1L1 in Pan-Cancer and Further Constructing LUAD and KICH Prediction Models (2023-12-18)
期刊：JOURNAL OF PROTEOME RESEARCH
DOI：10.1021/acs.jproteome.3c00655
影响因子 ：4.4
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , HK-2 细胞 , A-498 细胞 , MEM 培养基 , RPMI-1640 培养基 , Ham's F-12K 培养基
-
The induction of ferroptosis by KLF11/NCOA4 axis: the inhibitory role in clear cell renal cell carcinoma (2023-08-29)
期刊：Human Cell
DOI：10.1007/s13577-023-00973-9
影响因子 ：4.3
引用产品： HK-2 细胞 , 769-P 细胞 , McCoy's 5A 培养基
-
Silencing of adipocyte enhancer-binding protein 1 (AEBP1) alleviates renal fibrosis in vivo and in vitro via inhibition of the β-catenin signaling pathway (2023-02-04)
期刊：Human Cell
DOI：10.1007/s13577-023-00859-w
影响因子 ：4.3
-
Zinc Oxide Nanoparticles Induce Renal Injury by Initiating Oxidative Stress, Mitochondrial Damage and Apoptosis in Renal Tubular Epithelial Cells (2023-04-29)
期刊：BIOLOGICAL TRACE ELEMENT RESEARCH
DOI：10.1007/s12011-023-03683-3
影响因子 ：3.9
引用产品： HK-2 细胞
-
Mixed-ligand copper(II) hydrazone complexes: Synthesis, structure, and anti-lung cancer properties (2023-01-19)
期刊：JOURNAL OF MOLECULAR STRUCTURE
DOI：10.1016/j.molstruc.2023.134986
影响因子 ：3.8
引用产品： A549 [A-549] 细胞 , A549/DDP 细胞 , HK-2 细胞
-
Identification of an unrecognized circRNA associated with development of renal fibrosis (2023-01-04)
期刊：Frontiers in Genetics
影响因子 ：3.7
引用产品： HK-2 细胞
-
Nephropathy Is Aggravated by Fatty Acids in Diabetic Kidney Disease through Tubular Epithelial Cell Necroptosis and Is Alleviated by an RIPK-1 Inhibitor (2023-03-17)
期刊：Kidney Diseases
影响因子 ：3.7
引用产品： HK-2 细胞
-
Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential therapeutic target AJAP1 (2023-05-29)
期刊：JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI：10.1007/s00432-023-04877-x
影响因子 ：3.6
引用产品： HK-2 细胞 , Caki-1 细胞 , OS-RC-2 细胞
-
Circ_0006944 aggravates LPS-induced HK2 cell injury via modulating miR-205-5p/UBL4A pathway (2023-11-22)
期刊：AUTOIMMUNITY
DOI：10.1080/08916934.2023.2276066
影响因子 ：3.5
引用产品： HK-2 细胞
-
Integrating multi-level interactive network and in vivo/vitro studies to explore the protective mechanism of Ampelopsis grossedentata in hyperuricemia (2023-11-04)
期刊：FITOTERAPIA
DOI：10.1016/j.fitote.2023.105718
影响因子 ：3.4
引用产品： HK-2 细胞
-
Allicin ameliorates sepsis-induced acute kidney injury through Nrf2/HO-1 signaling pathway (2023-09-05)
期刊：Journal of Natural Medicines
DOI：10.1007/s11418-023-01745-3
影响因子 ：3.3
引用产品： HK-2 细胞
-
A latent reversible ratiometric optical pH sensing probe based on phenylboronic acid for alkaline pH detection and applications in test paper and alkalotic HK-2 cells (2023-05-10)
期刊：NEW JOURNAL OF CHEMISTRY
影响因子 ：3.3
引用产品： HK-2 细胞
-
Knockdown of KLF5 ameliorates renal fibrosis in MRL/lpr mice via inhibition of MX1 transcription (2023-07-27)
期刊：Immunity Inflammation and Disease
DOI：10.1002/iid3.937
影响因子 ：3.2
引用产品： HK-2 细胞
-
Circ_0068087 knockdown attenuates high-glucose-induced human tubular epithelial cell injury in a microribonucleic acid/progestin and adipoQ receptor?3-dependent manner in diabetic nephropathy (2023-11-20)
期刊：Journal of Diabetes Investigation
影响因子 ：3.2
引用产品： HK-2 细胞 , MEM (含NEAA) 培养基
-
CircUSP42 ameliorates LPS-induced human renal epithelial cells in vitro by regulating the miR-182-5p/DUSP1 axis (2023-10-17)
期刊：SHOCK
DOI：10.1097/SHK.0000000000002229
影响因子 ：3.1
引用产品： HK-2 细胞
-
Exosomal circVMA21 derived from adipose-derived stem cells alleviates sepsis-induced acute kidney injury by targeting miR-16-5p (2023-07-12)
期刊：SHOCK
DOI：10.1097/SHK.0000000000002179
影响因子 ：3.1
引用产品： 小鼠脂肪间充质干细胞成骨诱导分化培养基 , 小鼠脂肪间充质干细胞成脂诱导分化培养基 , HK-2 细胞
-
CircNRIP1 KNOCKDOWN ALLEVIATES LIPOPOLYSACCHARIDE-INDUCED HUMAN KIDNEY 2 CELL APOPTOSIS AND INFLAMMATION THROUGH miR-339-5p/OXSR1 PATHWAY (2023-03-26)
期刊：SHOCK
DOI：10.1097/SHK.0000000000002057
影响因子 ：3.1
引用产品： HK-2 细胞
-
MicroRNA-192-5p downregulates Fat Mass and Obesity-associated Protein to aggravate renal ischemia/reperfusion injury (2023-12-22)
期刊：RENAL FAILURE
DOI：10.1080/0886022X.2023.2285869
影响因子 ：3.0
引用产品： HK-2 细胞
-
Exploratory metabolomic analysis based on UHPLC-Q-TOF-MS/MS to study hypoxia-reoxygenation energy metabolic alterations in HK-2 cells (2023-05-29)
期刊：RENAL FAILURE
DOI：10.1080/0886022X.2023.2186715
影响因子 ：3.0
引用产品： HK-2 细胞
-
TIGAR protects against adenine-induced ferroptosis in human proximal tubular epithelial cells by activating the mTOR/S6KP70 axis (2023-05-04)
期刊：NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
DOI：10.1080/01635581.2023.2203353
影响因子 ：2.9
引用产品： HK-2 细胞
-
Anemonin inhibits sepsis-induced acute kidney injury via mitigating inflammation and oxidative stress (2023-08-17)
期刊：BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
DOI：10.1002/bab.2504
影响因子 ：2.8
引用产品： HK-2 细胞
-
Panax notoginseng Saponins Alleviate LPS-induced Fibrosis of HK-2 Cells by Inhibiting the Activation of NLRP3 Inflammasome and Pyroptosis (2023-05-24)
期刊：CURRENT PHARMACEUTICAL BIOTECHNOLOGY
DOI：10.2174/1389201024666230417084507
影响因子 ：2.8
引用产品： HK-2 细胞 , HK-2细胞专用培养基
-
Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress (2023-07-20)
期刊：BMC Molecular and Cell Biology
DOI：10.1186/s12860-023-00485-2
影响因子 ：2.8
引用产品： HK-2 细胞
-
Liuwei Dihuang Decoction Drug-containing Serum Attenuates Transforming Growth Factor-β1-induced Epithelial-mesenchymal Transition in HK-2 Cells by Inhibiting NF-κB/Snail Signaling Pathway (2023-03-24)
期刊：CURRENT PHARMACEUTICAL BIOTECHNOLOGY
DOI：10.2174/1389201024666230228100718
影响因子 ：2.8
引用产品： HK-2 细胞 , DMEM高糖 培养基 , 特级胎牛血清
-
Shen Qi Wan-Containing Serum Alleviates Renal Interstitial Fibrosis via Restraining Notch1-Mediated Epithelial-Mesenchymal Transition (2023-02-06)
期刊：Evidence-based Complementary and Alternative Medicine
影响因子 ：2.7
引用产品： HK-2 细胞 , HK-2细胞专用培养基
-
Tiao-Bu-Fei-Shen Formula Improves Glucocorticoid Resistance of Chronic Obstructive Pulmonary Disease via Downregulating the PI3K-Akt Signaling Pathway and Promoting GRα Expression (2023-02-11)
期刊：Evidence-based Complementary and Alternative Medicine
影响因子 ：2.7
引用产品： HK-2 细胞
-
Circ_0068087 Promotes High Glucose-Induced Human Renal Tubular Cell Injury through Regulating miR-106a-5p/ROCK2 Pathway (2023-04-20)
期刊：NEPHRON
影响因子 ：2.5
-
Resveratrol Inhibits circ_0074371-related Pathway to Alleviate Sepsis-induced Acute Kidney Injury (2023-09-20)
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-023-10517-3
影响因子 ：2.4
引用产品： HK-2 细胞
-
Coptisine mitigates diabetic nephropathy via repressing the NRLP3 inflammasome (2023-05-11)
期刊：Open Life Sciences
影响因子 ：2.2
-
Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation (2023-12-21)
期刊：Translational Andrology and Urology
影响因子 ：2.0
引用产品： HK-2 细胞 , MEM (含NEAA) 培养基
-
GDF11, a target of miR-32-5p, suppresses high-glucose-induced mitochondrial dysfunction and apoptosis in HK-2 cells through PI3K/AKT signaling activation (2023-02-07)
期刊：INTERNATIONAL UROLOGY AND NEPHROLOGY
DOI：10.1007/s11255-023-03495-3
影响因子 ：2.0
引用产品： HK-2 细胞
-
A Novel Tumor Mutation Burden Related lncRNA Signature Identified Prognosis and Tumor Immune Microenvironment Features in Clear Cell Renal Cell Carcinoma (2023-07-01)
期刊：COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
DOI：10.2174/1386207325666220926123923
影响因子 ：1.8
引用产品： HK-2 细胞 , 786-O [786-0] 细胞 , 769-P 细胞 , ACHN 细胞 , Ham's F-12K 培养基
-
The damage mechanism of uranium(VI) to HK-2 cells (2023-03-01)
期刊：JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
DOI：10.1007/s10967-023-08843-2
影响因子 ：1.6
引用产品： HK-2 细胞
-
LncRNA HOX transcript antisense RNA mediates hyperglycemic-induced injury in the renal tubular epithelial cell via the miR-126-5pAkt axis (2023-09-27)
期刊：Aging Medicine
影响因子 ：
引用产品： HK-2 细胞
-
A Water-Soluble AIEgen for Noninvasive Diagnosis of Kidney Fibrosis via SWIR Fluorescence and Photoacoustic Imaging (2022-10-12)
期刊：ADVANCED MATERIALS
影响因子 ：32.1
引用产品： HK-2 细胞
-
Adropin Carried by Reactive Oxygen Species-Responsive Nanocapsules Ameliorates Renal Lipid Toxicity in Diabetic Mice (2022-08-11)
期刊：ACS Applied Materials & Interfaces
影响因子 ：10.4
引用产品： HK-2 细胞
-
Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma (2022-09-30)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2022.1021935
影响因子 ：8.8
引用产品： ACHN 细胞 , HK-2 细胞 , Caki-2 细胞 , A-498 细胞 , Caki-1 细胞 , 786-O [786-0] 细胞 , OS-RC-2 细胞 , 769-P 细胞
-
Protective effects of Polygonatum kingianum polysaccharides and aqueous extract on uranium-induced toxicity in human kidney (HK-2) cells (2022-01-14)
期刊：International Journal Of Biological Macromolecules
DOI：10.1016/j.ijbiomac.2022.01.043
影响因子 ：8.2
引用产品： HK-2 细胞
-
6-Shogaol Exhibits a Promoting Effect with Tax via Binding HSP60 in Non-Small-Cell Lung Cancer (2022-11-19)
期刊：Cells
影响因子 ：7.7
引用产品： A-375 细胞 , A549 [A-549] 细胞 , H8 细胞 , U251 细胞 , 3T3-L1 细胞 , PANC-1 细胞 , TSSCA 细胞 , HK-2 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基
-
Dioscin Protects against Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling (2022-12-11)
期刊：Antioxidants
影响因子 ：7.7
引用产品： HK-2 细胞
-
Aluminum exposure induces nephrotoxicity via fibrosis and apoptosis through the TGF-β1/Smads pathway in vivo and in vitro (2022-12-13)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2022.114422
影响因子 ：7.1
引用产品： HK-2 细胞
-
PD-1 Targeted Nanoparticles Inhibit Activated T Cells and Alleviate Autoimmunity via Suppression of Cellular Energy Metabolism Mediated by PKM2 (2022-09-17)
期刊：International Journal of Nanomedicine
影响因子 ：7.0
引用产品： HK-2 细胞
-
Tumor Cell-Derived Exosomal circ-PRKCI Promotes Proliferation of Renal Cell Carcinoma via Regulating miR-545-3p/CCND1 Axis (2022-12-25)
期刊：Cancers
影响因子 ：6.6
引用产品： 786-O [786-0] 细胞 , ACHN 细胞 , Caki-1 细胞 , 769-P 细胞 , HK-2 细胞
-
Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury (2022-11-23)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2022.1043945
影响因子 ：6.0
引用产品： HK-2 细胞
-
Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis. (2022-09-21)
期刊：Frontiers in Pharmacology
影响因子 ：6.0
引用产品： SV-HUC-1 细胞 , T24 [T-24] 细胞 , 5637 细胞 , HK-2 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞 , RWPE-1 细胞 , PC-3 细胞 , DU 145 细胞 , Ham's F-12K 培养基 , DMEM高糖 培养基 , 人前列腺上皮细胞完全培养基 , RPMI-1640 培养基
-
Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway (2022-10-07)
期刊：Frontiers in Pharmacology
影响因子 ：6.0
引用产品： HK-2 细胞
-
T-2 Toxin Induces Kidney Fibrosis via the mtROS-NLRP3-Wnt/β-Catenin Axis (2022-10-14)
期刊：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 ：5.9
引用产品： HK-2 细胞 , 青霉素-链霉素溶液 (双抗)，100×
-
Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA?binding protein RBFOX1 in this disease (2022-01-19)
期刊：International Journal Of Molecular Medicine
影响因子 ：5.4
引用产品： HK-2 细胞
-
Up-regulation of the human-specific CHRFAM7A gene protects against renal fibrosis in mice with obstructive nephropathy (2022-12-07)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：5.3
引用产品： HK-2 细胞
-
Chronic intermittent hypoxia induces the pyroptosis of renal tubular epithelial cells by activating the NLRP3 inflammasome (2022-03-09)
期刊：Bioengineered
DOI：10.1080/21655979.2022.2047394
影响因子 ：4.9
引用产品： HK-2 细胞
-
Prognostic value and immunological characteristics of a novel cuproptosis-related long noncoding RNAs risk signature in kidney renal clear cell carcinoma (2022-11-03)
期刊：Frontiers in Genetics
DOI：10.3389/fgene.2022.1009555
影响因子 ：4.8
引用产品： HK-2 细胞
-
Circ_0060077 Knockdown Alleviates High-Glucose-Induced Cell Apoptosis, Oxidative Stress, Inflammation and Fibrosis in HK-2 Cells via miR-145-5p/VASN Pathway (2022-06-21)
期刊：INFLAMMATION
DOI：10.1007/s10753-022-01649-6
影响因子 ：4.7
引用产品： HK-2 细胞 , MEM（含NEAA） 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液（双抗），100×
-
Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma (2022-02-16)
期刊：Journal of Inflammation Research
影响因子 ：4.5
引用产品： Caki-1 细胞 , 769-P 细胞 , 786-O [786-0] 细胞 , ACHN 细胞 , HK-2 细胞
-
Role of (Pro)Renin Receptor in Cyclosporin A-Induced Nephropathy (2022-01-24)
期刊：AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
DOI：10.1152/ajprenal.00332.2021
影响因子 ：4.2
引用产品： HK-2 细胞
-
Knockdown of circ_0003928 ameliorates high glucose-induced dysfunction of human tubular epithelial cells through the miR-506-3p/ HDAC4 pathway in?diabetic nephropathy (2022-04-07)
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-022-00679-y
影响因子 ：4.2
引用产品： HK-2 细胞
-
Downregulation of circ-ZNF644 alleviates LPS-induced HK2 cell injury via miR-335-5p/HIPK1 axis (2022-09-02)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.1
-
CircZNF644 aggravates lipopolysaccharide-induced HK-2 cell impairment via the miR-140-5p/MLKL axis (2022-08-17)
期刊：JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
DOI：10.1007/s10863-022-09946-3
影响因子 ：3.9
引用产品： HK-2 细胞 , MEM 培养基 , 青霉素-链霉素溶液 (双抗)，100× , 特级胎牛血清
-
Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate (2022-04-01)
期刊：CELL STRESS & CHAPERONES
DOI：10.1007/s12192-022-01266-0
影响因子 ：3.8
引用产品： 293 [HEK-293] 细胞 , HK-2 细胞
-
Identifying the mechanisms and molecular targets of Hongjingtian injection on treatment of TGFβ1-induced HK-2 cells: coupling network pharmacology with experimental verification (2022-12-01)
期刊：Annals of Translational Medicine
影响因子 ：3.6
引用产品： HK-2 细胞
-
High-glucose induced toxicity in HK-2 cells can be alleviated by inhibition of miRNA-320c (2022-08-15)
期刊：RENAL FAILURE
DOI：10.1080/0886022X.2022.2106874
影响因子 ：3.2
引用产品： HK-2 细胞
-
Silencing circ_0074371 inhibits the progression of sepsis-induced acute kidney injury by regulating miR-330-5p/ELK1 axis (2022-08-22)
期刊：MAMMALIAN GENOME
DOI：10.1007/s00335-022-09961-0
影响因子 ：3.2
引用产品： HK-2 细胞 , 青霉素-链霉素溶液 (双抗)，100×
-
High Glucose-Induced Human Kidney Cell Apoptosis and Inflammatory Injury Are Alleviated by Circ_0008529 Knockdown via Circ_0008529-Mediated miR-485-5p/WNT2B Signaling (2022-08-01)
期刊：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
DOI：10.1007/s12010-022-04088-z
影响因子 ：3.1
引用产品： HK-2 细胞
-
GBP5 Inhibition Ameliorates the Progression of Lupus Nephritis by Suppressing NLRP3 Inflammasome Activation (2022-09-29)
期刊：IMMUNOLOGICAL INVESTIGATIONS
DOI：10.1080/08820139.2022.2122834
影响因子 ：3.0
引用产品： HK-2 细胞
-
Design, Synthesis and Biological Evaluation of Novel 1, 3, 4-Oxadiazole PD176252 Analogues as Potential GRPR Inhibitors (2022-10-01)
期刊：Anti-Cancer Agents in Medicinal Chemistry
DOI：10.2174/1871520622666220501162813
影响因子 ：2.5
引用产品： PC-3 细胞 , HGC-27 细胞 , HCT 116 细胞 , SW480 [SW-480] 细胞 , A549 [A-549] 细胞 , HK-2 细胞
-
Forkhead box A2-mediated lncRNA SOX2OT up-regulation alleviates oxidative stress and apoptosis of renal tubular epithelial cells by promoting SIRT1 expression in diabetic nephropathy (2022-12-28)
期刊：NEPHROLOGY
影响因子 ：2.4
引用产品： HK-2 细胞
-
LncRNA NEAT1 knockdown ameliorates LPS-induced human kidney injury by mediating the miR-330-5p/FOXO3 axis (2022-04-01)
期刊：INTERNATIONAL UROLOGY AND NEPHROLOGY
DOI：10.1007/s11255-022-03179-4
影响因子 ：2.0
引用产品： HK-2 细胞
-
Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression (2022-11-30)
期刊：TRANSPLANT IMMUNOLOGY
DOI：10.1016/j.trim.2022.101764
影响因子 ：2.0
引用产品： HK-2 细胞 , OS-RC-2 细胞 , ACHN 细胞 , 786-O [786-0] 细胞
-
A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy (2021-07-20)
期刊：Journal Of Colloid And Interface Science
DOI：10.1016/j.jcis.2021.07.080
影响因子 ：9.9
引用产品： HK-2 细胞
-
Liproxstatin-1 attenuates unilateral ureteral obstruction-induced renal fibrosis by inhibiting renal tubular epithelial cells ferroptosis (2021-09-11)
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-04137-1
影响因子 ：9.0
引用产品： HK-2 细胞
-
A nanosensor for precise discrimination of nephrotoxic drug mechanisms via dynamic fluorescence fingerprint strategy (2021-03-20)
期刊：Analytica Chimica Acta
影响因子 ：6.2
引用产品： MEM非必需氨基酸溶液 (NEAA)，100× , HK-2 细胞
-
Senkyunolide I alleviates renal Ischemia-Reperfusion injury by inhibiting oxidative stress, endoplasmic reticulum stress and apoptosis (2021-11-30)
期刊：International Immunopharmacology
DOI：10.1016/j.intimp.2021.108393
影响因子 ：5.6
引用产品： HK-2 细胞 , MEM (含NEAA) 培养基 , 青霉素-链霉素溶液 (双抗)，100× , 特级胎牛血清
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Migration of Human Renal Tubular Epithelial Cells in Response to Physiological Electric Signals (2021-09-14)
期刊：Frontiers in Cell and Developmental Biology
影响因子 ：5.5
引用产品： HK-2 细胞 , 293 [HEK-293] 细胞
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Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway (2021-07-24)
期刊：Journal Of Ethnopharmacology
影响因子 ：5.4
引用产品： HK-2 细胞
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MicroRNA 181a-2-3p Alleviates the Apoptosis of Renal Tubular Epithelial Cells via Targeting GJB2 in Sepsis-Induced Acute Kidney Injury (2021-06-23)
期刊：MOLECULAR AND CELLULAR BIOLOGY
影响因子 ：5.3
引用产品： HK-2 细胞 , TCMK-1 细胞
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Downregulation of IRF2 Alleviates Sepsis-Related Acute Kidney Injury in vitro and in vivo (2021-12-22)
期刊：Drug Design Development and Therapy
影响因子 ：4.8
引用产品： HK-2 细胞
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Knockdown of circ-FANCA alleviates LPS-induced HK2 cell injury via targeting miR-93-5p/OXSR1 axis in septic acute kidney injury (2021-01-19)
期刊：Diabetology & Metabolic Syndrome
DOI：10.1186/s13098-021-00625-8
影响因子 ：4.8
引用产品： HK-2 细胞 , MEM (含NEAA) 培养基
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Anti-Malignant Ascites Effect of Total Diterpenoids from Euphorbiae ebracteolatae Radix Is Attributable to Alterations of Aquaporins via Inhibiting PKC Activity in the Kidney (2021-02-10)
期刊：Molecules
影响因子 ：4.6
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Overexpression of TOLLIP Protects against Acute Kidney Injury after Paraquat Intoxication through Inhibiting NLRP3 Inflammasome Activation Modulated by Toll-Like Receptor 2/4 Signaling (2021-07-15)
期刊：Mediators Of Inflammation
影响因子 ：4.6
引用产品： HK-2 细胞
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Metabolomics analysis underlay mechanisms in the renal impairment of mice caused by combination of aflatoxin M1 and ochratoxin A (2021-06-11)
期刊：Toxicology
影响因子 ：4.5
引用产品： HK-2 细胞
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Loganin Attenuates Septic Acute Renal Injury with the Participation of AKT and Nrf2/HO-1 Signaling Pathways (2021-02-11)
期刊：Drug Design Development and Therapy
影响因子 ：4.3
引用产品： HK-2 细胞
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The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi-omics study (2021-11-10)
期刊：Cancer Medicine
影响因子 ：4.0
引用产品： 786-O [786-0] 细胞 , A-498 细胞 , HK-2 细胞
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HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma (2021-02-19)
期刊：Cell Biology International
影响因子 ：3.9
引用产品： HK-2 细胞 , A-498 细胞 , 786-O [786-0] 细胞 , Caki-1 细胞
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CircVMA21 ameliorates lipopolysaccharide (LPS)-induced HK-2 cell injury depending on the regulation of miR-7-5p/PPARA (2021-12-13)
期刊：Autoimmunity
DOI：10.1080/08916934.2021.2012764
影响因子 ：3.5
引用产品： HK-2 细胞 , 青霉素-链霉素溶液 (双抗)，100× , 特级胎牛血清
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Circular RNA circ_0068,888 protects against lipopolysaccharide-induced HK-2?cell injury via sponging microRNA-21–5p (2021-02-12)
期刊：Biochemical And Biohysical Research Communicattons
DOI：10.1016/j.bbrc.2020.12.018
影响因子 ：3.1
引用产品： HK-2 细胞
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LncRNA NKILA knockdown promotes cell viability and represses cell apoptosis, autophagy and inflammation in lipopolysaccharide-induced sepsis model by regulating miR-140-5p/CLDN2 axis (2021-04-28)
期刊：Biochemical and Biophysical Research Communications
DOI：10.1016/j.bbrc.2021.04.074
影响因子 ：3.1
引用产品： 293T [HEK-293T] 细胞 , HK-2 细胞
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Aldosterone Induces the Proliferation of Renal Tubular Epithelial Cells In Vivo but Not In Vitro (2021-07-28)
期刊：Journal Of The Renin-Angiotensin-Aldosterone System
影响因子 ：2.9
引用产品： HK-2 细胞
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Identification of hub genes and transcription factor-miRNA-mRNA pathways in mice and human renal ischemia-reperfusion injury (2021-10-26)
期刊：PeerJ
影响因子 ：2.7
引用产品： HK-2 细胞
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Thioredoxin relieves lipopolysaccharide?induced acute kidney injury in mice by reducing inflammation, oxidative stress and apoptosis (2021-04-15)
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.7
引用产品： HK-2 细胞
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Long Non-Coding RNA CASC2 Overexpression Ameliorates Sepsis-Associated Acute Kidney Injury by Regulating MiR-545-3p/PPARA axis (2021-05-03)
期刊：Journal of Surgical Research
影响因子 ：2.2
引用产品： HK-2 细胞 , 293 [HEK-293] 细胞
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Advanced Oxidation Protein Product Promotes Oxidative Accentuation in Renal Epithelial Cells via the Soluble (Pro)renin Receptor-Mediated Intrarenal Renin-Angiotensin System and Nox4-H2O2 Signaling (2021-11-26)
期刊：Oxidative Medicine and Cellular Longevity
影响因子 ：0.0
引用产品： HK-2 细胞 , DMEM/F12 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100×
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ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway (2020-08-22)
期刊：Cell Death & Disease
DOI：10.1038/s41419-020-02912-0
影响因子 ：9.0
引用产品： HK-2 细胞
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Involvement of miR‐27a‐3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress (2020-07-21)
期刊：Journal Of Cellular Physiology
影响因子 ：5.6
引用产品： HK-2 细胞
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Involvement of GPX4 in irisin's protection against ischemia reperfusion-induced acute kidney injury (2020-06-24)
期刊：JOURNAL OF CELLULAR PHYSIOLOGY
影响因子 ：5.5
引用产品： HK-2 细胞
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Sodium butyrate ameliorates deoxycorticosterone acetate/salt-induced hypertension and renal damage by inhibiting the MR/SGK1 pathway (2020-09-09)
期刊：Hypertension Research
DOI：10.1038/s41440-020-00548-3
影响因子 ：5.4
引用产品： HK-2 细胞 , 青霉素-链霉素溶液 (双抗)，100×
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Soluble (pro)renin receptor promotes the fibrotic response in renal proximal tubule epithelial cells in vitro via the Akt/β-catenin/Snail signaling pathway (2020-11-01)
期刊：American Journal Of Physiology-Renal Physiology
DOI：10.1152/ajprenal.00197.2020
影响因子 ：4.2
引用产品： HK-2 细胞
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Rapid and sensitive detection of NGAL for the prediction of acute kidney injury via a polydopamine nanosphere/aptamer nanocomplex coupled with DNase I-assisted recycling amplification (2020-04-01)
期刊：Analyst
影响因子 ：4.2
引用产品： HK-2 细胞
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δ‐Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β‐catenin nuclear localization and activating its downstream target genes (2020-01-28)
期刊：Cancer Medicine
影响因子 ：4.0
引用产品： HK-2 细胞 , A-498 细胞 , ACHN 细胞 , 786-O [786-0] 细胞
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Hydroxytyrosol inhibits apoptosis in ischemia/reperfusion-induced acute kidney injury via activating Sonic Hedgehog signaling pathway (2020-12-01)
期刊：European Review for Medical and Pharmacological Sciences
DOI：10.26355/eurrev_202012_24032
影响因子 ：3.8
引用产品： HK-2 细胞
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Comprehensive analysis of the HOXA gene family identifes HOXA13as a novel oncogenic gene in kidney renal clear cell carcinoma (2020-05-22)
期刊：JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI：10.1007/s00432-020-03259-x
影响因子 ：3.6
引用产品： 786-O [786-0] 细胞 , Caki-1 细胞 , A-498 细胞 , HK-2 细胞
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MiR-32-5p knockdown inhibits epithelial to mesenchymal transition and renal fibrosis by targeting SMAD7 in diabetic nephropathy: (2020-09-22)
期刊：Human & Experimental Toxicology
影响因子 ：2.8
引用产品： HK-2 细胞
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Efficacy of Obcordata A from Aspidopterys obcordata on Kidney Stones by Inhibiting NOX4 Expression (2019-03-21)
期刊：Molecules
影响因子 ：4.6
引用产品： HK-2 细胞
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Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation (2019-11-21)
期刊：Yonsei Med J
DOI：10.3349/ymj.2019.60.12.1195
影响因子 ：2.4
引用产品： HK-2 细胞
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Rhodomyrtosone B, a membrane-targeting anti-MRSA natural acylgphloroglucinol from Rhodomyrtus tomentosa (2018-09-07)
期刊：Journal Of Ethnopharmacology
影响因子 ：5.4
引用产品： HK-2 细胞
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(Pro)renin receptor mediates albumin-induced cellular responses: role of site-1 protease-derived soluble (pro)renin receptor in renal epithelial cells (2017-12-08)
期刊：American Journal of Physiology-Cell Physiology
DOI：10.1152/ajpcell.00006.2017
影响因子 ：5.5
引用产品： HK-2 细胞
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