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  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)

HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)

货号:CL-0109

规格:1×10⁶cells/T25培养瓶

价格: ¥1600

生长培养基:MEM(含NEAA)10% FBS1% P/S

数量: - +

  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
  • HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)

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产品概述
产品信息
名称 HK-2 (人肾皮质近曲小管上皮细胞) (STR鉴定正确)
别称 Hk-2; HK2; Human Kidney-2
种属
生长特性 贴壁细胞
细胞形态 上皮细胞样
冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
培养方案A(默认)
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
推荐传代比例 1:2-1:4
推荐换液频率 2-3次/周
参考资料(来源文献)
背景描述 HK-2细胞属源于正常肾的近曲小管细胞,通过导入HPV-16 E6/E7基因而获得永生化。将含有HPV-16 E6/E7基因的重组的逆转录病毒载体pLXSN 16 E6/E7转染外生包装细胞Psi-2;Psi-2细胞产生的病毒再去感染兼嗜性包装细胞系PA317,最后将PA317细胞产生的病毒颗粒导入正常的肾皮质近曲小管细胞。尽管pLXSN 16 E6/E7中含有新霉素抗性,但未用G418筛选转导克隆。Southern和FISH分析显示,HK-2细胞来源于单克隆。PCR检测证实,HK-2细胞基因组中含有E6/E7基因。
年龄(性别) 男性;成人
组织来源 肾,皮质/近端小管
细胞类型 转化细胞系
生物安全等级 BSL-2
受体表达情况 epidermal growth factor (EGF), expressed
基因表达情况 alkaline phosphatase; gamma glutamyltranspeptidase; leucine aminopeptidase; acid phosphatase; cytokeratin; alpha 3, beta 1 integrin; fibronectin
保藏机构 ATCC; CRL-2190 BCRC; 60097
STR鉴定
  • STR位点信息
    Amelogenin X
    CSF1PO 13
    D2S1338 17,25
    D3S1358 16
    D5S818 12
    D7S820 10,11
    D8S1179 10,14
    D13S317 9
    D16S539 12
    D18S51 12
    D19S433 15,15.2
    D21S11 28,30
    FGA 20
    PentaD 9,12
    PentaE 10,11
    TH01 9
    TPOX 8,9
    vWA 17,18
    D6S1043 12,13
    D12S391 17.3,22
    D2S441 11,12
  • STR鉴定图
参考文献
文献列表
  • New Sight of Renal Toxicity Caused by UV-Aged Polystyrene Nanoplastics: Induced Ferroptosis via Adsorption of Transferrin (2024-01-04)

    期刊:Small

    DOI:10.1002/smll.202309369

    影响因子 :13.3

    引用产品: HK-2 细胞

  • Artesunate-Nanoliposome-TPP, a Novel Drug Delivery System That Targets the Mitochondria, Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Stress and Inflammatory Effects (2024-02-11)

    期刊:International Journal of Nanomedicine

    DOI:10.2147/IJN.S444076

    影响因子 :8.0

    引用产品: HK-2 细胞

  • 2-Dodecyl-6-Methoxycyclohexa-2, 5-Diene-1, 4-Dione isolated from Averrhoa carambola L. root inhibits high glucose-induced EMT in HK-2 cells through targeting the regulation of miR-21–5p/Smad7 signaling pathway (2024-02-17)

    期刊:BIOMEDICINE & PHARMACOTHERAPY

    DOI:10.1016/j.biopha.2024.116280

    影响因子 :7.5

    引用产品: HK-2 细胞

  • High CD133 expression in proximal tubular cells in diabetic kidney disease: good or bad? (2024-02-16)

    期刊:Journal of Translational Medicine

    DOI:10.1186/s12967-024-04950-0

    影响因子 :7.4

    引用产品: HK-2 细胞 ,  NRK-53E 细胞

  • The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury (2024-01-02)

    期刊:Journal of Translational Medicine

    DOI:10.1186/s12967-023-04793-1

    影响因子 :7.4

    引用产品: HK-2 细胞

  • Urinary miR-185-5p is a biomarker of renal tubulointerstitial fibrosis in IgA nephropathy (2024-02-15)

    期刊:Frontiers in Immunology

    DOI:10.3389/fimmu.2024.1326026

    影响因子 :7.3

    引用产品: HK-2 细胞

  • Deubiquitinating enzyme OTUD4 stabilizes RBM47 to induce ATF3 transcription: a novel mechanism underlying the restrained malignant properties of ccRCC cells (2024-03-30)

    期刊:APOPTOSIS

    DOI:10.1007/s10495-024-01953-6

    影响因子 :7.2

    引用产品: HK-2 细胞 ,  Caki-1 细胞 ,  769-P 细胞 ,  786-O [786-0] 细胞 ,  SW839 细胞

  • Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis (2024-03-14)

    期刊:ACS Pharmacology & Translational Science

    DOI:10.1021/acsptsci.4c00010

    影响因子 :6.0

    引用产品: HK-2 细胞

  • Investigating HMGB1 as a Potential Serum Biomarker for Early Diabetic Nephropathy Monitoring by Quantitative Proteomics (2024-01-08)

    期刊:iScience

    DOI:10.1016/j.isci.2024.108834

    影响因子 :5.8

    引用产品: HK-2 细胞

  • Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport (2024-03-04)

    期刊:JOURNAL OF ETHNOPHARMACOLOGY

    DOI:10.1016/j.jep.2024.117946

    影响因子 :5.4

    引用产品: HK-2 细胞

  • Inhibitory effect of Incarvillea diffusa Royle extract in the formation of calcium oxalate nephrolithiasis by regulating ROS-induced Nrf2/HO-1 pathway in rats (2024-01-23)

    期刊:JOURNAL OF ETHNOPHARMACOLOGY

    DOI:10.1016/j.jep.2023.117619

    影响因子 :5.4

    引用产品: HK-2 细胞

  • Sleeve gastrectomy links the attenuation of diabetic kidney disease to the inhibition of renal tubular ferroptosis through down-regulating TGF-β1/Smad3 signaling pathway (2024-03-21)

    期刊:JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

    DOI:10.1007/s40618-023-02267-1

    影响因子 :5.4

    引用产品: HK-2 细胞

  • HMGN1 down-regulation in the diabetic kidney attenuates tubular cells injury and protects against renal inflammation via suppressing MCP-1 and KIM-1 expression through TLR4 (2024-02-27)

    期刊:JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

    DOI:10.1007/s40618-023-02292-0

    影响因子 :5.4

    引用产品: HK-2 细胞

  • Disulfideptosis-associated lncRNAs reveal features of prognostic, immune escape, tumor mutation, and tumor malignant progression in renal clear cell carcinoma (2024-02-08)

    期刊:Aging-US

    DOI:10.18632/aging.205534

    影响因子 :5.2

    引用产品: 786-O [786-0] 细胞 ,  OS-RC-2 细胞 ,  A-498 细胞 ,  ACHN 细胞 ,  HK-2 细胞

  • Selenium binding protein 1 protects renal tubular epithelial cells from ferroptosis by upregulating glutathione peroxidase 4 (2024-03-20)

    期刊:CHEMICO-BIOLOGICAL INTERACTIONS

    DOI:10.1016/j.cbi.2024.110944

    影响因子 :5.1

    引用产品: HK-2 细胞

  • Arylacryl amides: Design, synthesis and the protection against cisplatin-induced acute kidney injury via TLR4/STING/NF-κB pathway (2024-03-21)

    期刊:BIOORGANIC CHEMISTRY

    DOI:10.1016/j.bioorg.2024.107303

    影响因子 :5.1

    引用产品: HK-2 细胞

  • The copper transporter, SLC31A1, transcriptionally activated by ELF3, imbalances copper homeostasis to exacerbate cisplatin-induced acute kidney injury through mitochondrial dysfunction (2024-03-09)

    期刊:CHEMICO-BIOLOGICAL INTERACTIONS

    DOI:10.1016/j.cbi.2024.110943

    影响因子 :5.1

    引用产品: HK-2 细胞

  • An aldose reductase inhibitor, WJ-39, ameliorates renal tubular injury in diabetic nephropathy by activating PINK1/Parkin signaling (2024-02-08)

    期刊:EUROPEAN JOURNAL OF PHARMACOLOGY

    DOI:10.1016/j.ejphar.2024.176376

    影响因子 :5.0

    引用产品: HK-2 细胞

  • TMEM16A inhibits renal tubulointerstitial fibrosis via Wnt/β-catenin signaling during hypertension nephropathy (2024-02-03)

    期刊:CELLULAR SIGNALLING

    DOI:10.1016/j.cellsig.2024.111088

    影响因子 :4.8

    引用产品: MEM 培养基 ,  HK-2 细胞

  • Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis (2024-03-20)

    期刊:Scientific Reports

    DOI:10.1038/s41598-024-56950-1

    影响因子 :4.6

    引用产品: HK-2 细胞 ,  人脐带间充质干细胞

  • Qi-dan-dihuang decoction ameliorates renal fibrosis in diabetic rats via p38MAPK/AKT/mTOR signaling pathway (2024-03-08)

    期刊:ENVIRONMENTAL TOXICOLOGY

    DOI:10.1002/tox.24179

    影响因子 :4.5

    引用产品: HK-2 细胞 ,  NRK-52E 细胞

  • Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways (2024-02-08)

    期刊:INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

    DOI:10.1016/j.biocel.2024.106549

    影响因子 :4.0

    引用产品: HK-2 细胞

  • Disruption of Autophagic Flux and Treatment with the PDPK1 Inhibitor GSK2334470 Synergistically Inhibit Renal Cell Carcinoma Pathogenesis (2024-01-20)

    期刊:Journal of Cancer

    DOI:10.7150/jca.92521

    影响因子 :3.9

    引用产品: 786-O [786-0] 细胞 ,  A-498 细胞 ,  HK-2 细胞

  • Excess iron accumulation mediated senescence in diabetic kidney injury (2024-03-14)

    期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

    DOI:10.1002/jbt.23683

    影响因子 :3.6

    引用产品: HBZY-1 细胞 ,  HK-2 细胞

  • Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC (2024-03-21)

    期刊:GENE

    DOI:10.1016/j.gene.2024.148403

    影响因子 :3.5

    引用产品: HK-2 细胞 ,  ACHN 细胞 ,  A-498 细胞 ,  786-O [786-0] 细胞 ,  OS-RC-2 细胞 ,  Caki-1 细胞 ,  RPMI-1640 培养基 ,  MEM 培养基

  • Andrographolide attenuates sepsis-induced acute kidney injury by inhibiting ferroptosis through the Nrf2/FSP1 pathway. (2024-03-12)

    期刊:FREE RADICAL RESEARCH

    DOI:10.1080/10715762.2024.2330413

    影响因子 :3.3

    引用产品: HK-2 细胞

  • CircACTR2 attenuated the effects of tetramethylpyrazine on human kidney cell injury (2024-03-01)

    期刊:JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

    DOI:10.1007/s10863-024-10001-6

    影响因子 :3.0

    引用产品: HK-2 细胞

  • FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent manner (2024-03-06)

    期刊:RENAL FAILURE

    DOI:10.1080/0886022X.2024.2322037

    影响因子 :3.0

    引用产品: HK-2 细胞 ,  MEM (含NEAA) 培养基 ,  特级胎牛血清 ,  青霉素-链霉素溶液 (双抗),100× ,  Hank's平衡盐溶液 (HBSS),含钙、镁,不含酚红

  • WTAP-mediated N6-methyladenosine modification promotes the inflammation, mitochondrial damage and ferroptosis of kidney tubular epithelial cells in acute kidney injury by regulating LMNB1 expression and activating NF-κB and JAK2/STAT3 pathways (2024-03-22)

    期刊:JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

    DOI:10.1007/s10863-024-10015-0

    影响因子 :3.0

    引用产品: HK-2 细胞 ,  青霉素-链霉素溶液 (双抗),100×

  • Decreased expression of TXNIP is associated with poor prognosis and immune infiltration in kidney renal clear cell carcinoma (2024-01-12)

    期刊:Oncology Letters

    DOI:10.3892/ol.2024.14230

    影响因子 :2.9

    引用产品: A-498 细胞 ,  HK-2 细胞

  • Clinical Significance of Apela in Acute Cardiorenal Insuffiency of Chronic Heart Failure (2024-01-18)

    期刊:KIDNEY & BLOOD PRESSURE RESEARCH

    DOI:10.1159/000536316

    影响因子 :2.8

    引用产品: THP-1 细胞 ,  人肾小球内皮细胞 ,  人肾小球系膜细胞 ,  HK-2 细胞 ,  DMEM高糖 培养基 ,  人肾小球内皮细胞完全培养基 ,  人肾小球系膜细胞完全培养基 ,  人肾小管上皮细胞完全培养基

  • Knockdown of circ-Gatad1 alleviates LPS induced HK2 cell injury via targeting miR-22-3p/TRPM7 axis in septic acute kidney (2024-03-05)

    期刊:BMC Nephrology

    DOI:10.1186/s12882-024-03513-1

    影响因子 :2.3

    引用产品: HK-2 细胞 ,  MEM 培养基 ,  特级胎牛血清 ,  青霉素-链霉素溶液 (双抗),100×

  • Cytosolic mtDNA–cGAS–STING axis contributes to sepsis-induced acute kidney injury via activating the NLRP3 inflammasome (2024-01-19)

    期刊:Clinical and Experimental Nephrology

    DOI:10.1007/s10157-023-02448-5

    影响因子 :2.3

    引用产品: HK-2 细胞 ,  HK-2细胞专用培养基

  • Cell division cycle 42 attenuates high glucose-treated renal tubular epithelial cell apoptosis, fibrosis, and inflammation, but activates the PAK1/AKT pathway (2024-02-28)

    期刊:Clinical and Experimental Nephrology

    DOI:10.1007/s10157-024-02468-9

    影响因子 :2.3

    引用产品: HK-2 细胞 ,  DMEM/F12 培养基 ,  青霉素-链霉素溶液 (双抗),100×

  • Ethanol extract of Abelmoschus manihot suppresses endoplasmic reticulum stress in contrast-induced nephropathy (2024-01-23)

    期刊:Asian Pacific Journal of Tropical Biomedicine

    DOI:10.4103/2221-1691.393577

    影响因子 :1.7

    引用产品: Annexin V-FITC/ PI荧光双染细胞凋亡检测试剂盒 ,  HK-2 细胞

  • Hypoxia-triggered tumor specific glutamine inhibition for reversing cisplatin resistance of chemotherapy (2023-11-27)

    期刊:CHEMICAL ENGINEERING JOURNAL

    DOI:10.1016/j.cej.2023.147692

    影响因子 :15.1

    引用产品: A549 [A-549] 细胞 ,  A549/DDP 细胞 ,  青霉素-链霉素溶液 (双抗),100× ,  HK-2 细胞

  • Self-oriented ferritin nanocages mitigate iron overload-induced oxidative stress for acute kidney injury (2023-05-02)

    期刊:CHEMICAL ENGINEERING JOURNAL

    DOI:10.1016/j.cej.2023.143227

    影响因子 :15.1

    引用产品: HK-2 细胞

  • Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition (2023-08-02)

    期刊:Science Advances

    DOI:10.1126/sciadv.adh7828

    影响因子 :13.6

    引用产品: HK-2 细胞

  • Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI (2023-03-21)

    期刊:Theranostics

    DOI:10.7150/thno.83353

    影响因子 :12.4

    引用产品: HK-2 细胞

  • Renal clearance of graphene oxide: glomerular filtration or tubular secretion and selective kidney injury association with its lateral dimension (2023-02-10)

    期刊:JOURNAL OF NANOBIOTECHNOLOGY

    DOI:10.1186/s12951-023-01781-x

    影响因子 :10.2

    引用产品: HK-2 细胞

  • Liraglutide abrogates nephrotoxic effects of chemotherapies (2023-02-04)

    期刊:PHARMACOLOGICAL RESEARCH

    DOI:10.1016/j.phrs.2023.106680

    影响因子 :9.3

    引用产品: HK-2 细胞

  • Aldehyde dehydrogenase 2 alleviates mitochondrial dysfunction by promoting PGC-1α-mediated biogenesis in acute kidney injury (2023-01-20)

    期刊:Cell Death & Disease

    DOI:10.1038/s41419-023-05557-x

    影响因子 :9.0

    引用产品: HK-2 细胞

  • circWSB1 promotes tumor progression in ccRCC via circWSB1/miR-182-5p/WSB1 axis (2023-11-24)

    期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

    DOI:10.1016/j.ijbiomac.2023.128338

    影响因子 :8.2

    引用产品: HK-2 细胞

  • Inhibition of intrarenal PRR-RAS pathway by Ganoderma lucidum polysaccharide peptides in proteinuric nephropathy (2023-10-16)

    期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

    DOI:10.1016/j.ijbiomac.2023.127336

    影响因子 :8.2

    引用产品: HK-2 细胞 ,  HK-2细胞专用培养基

  • Nephroprotective Effects of Selenium Nanoparticles Against Sodium Arsenite-Induced Damages (2023-06-12)

    期刊:International Journal of Nanomedicine

    DOI:10.2147/IJN.S413362

    影响因子 :8.0

    引用产品: HK-2 细胞

  • Celastrol alleviated acute kidney injury by inhibition of ferroptosis through Nrf2/GPX4 pathway (2023-08-18)

    期刊:BIOMEDICINE & PHARMACOTHERAPY

    DOI:10.1016/j.biopha.2023.115333

    影响因子 :7.5

    引用产品: MEM (含NEAA) 培养基 ,  青霉素-链霉素溶液 (双抗),100× ,  特级胎牛血清 ,  HK-2 细胞

  • Jiedu Tongluo Baoshen formula enhances renal tubular epithelial cell autophagy to prevent renal fibrosis by activating SIRT1/LKB1/AMPK pathway (2023-02-03)

    期刊:BIOMEDICINE & PHARMACOTHERAPY

    DOI:10.1016/j.biopha.2023.114340

    影响因子 :7.5

    引用产品: NRK-52E 细胞 ,  HK-2 细胞

  • Inhibition of ACSF2 protects against renal ischemia/reperfusion injury via mediating mitophagy in proximal tubular cells (2023-02-09)

    期刊:FREE RADICAL BIOLOGY AND MEDICINE

    DOI:10.1016/j.freeradbiomed.2023.02.003

    影响因子 :7.4

    引用产品: HK-2 细胞

  • TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage (2023-10-05)

    期刊:Journal of Translational Medicine

    DOI:10.1186/s12967-023-04351-9

    影响因子 :7.4

    引用产品: HK-2 细胞 ,  MEM (含NEAA) 培养基

  • Knockdown of NR3C1 inhibits the proliferation and migration of clear cell renal cell carcinoma through activating endoplasmic reticulum stress–mitophagy (2023-10-08)

    期刊:Journal of Translational Medicine

    DOI:10.1186/s12967-023-04560-2

    影响因子 :7.4

    引用产品: HK-2 细胞

  • Bioinformatics analysis reveals the potential role of matrix metalloproteinases in immunity and urolithiasis (2023-03-15)

    期刊:Frontiers in Immunology

    DOI:10.3389/fimmu.2023.1158379

    影响因子 :7.3

    引用产品: HK-2 细胞

  • Prognostic and tumor microenvironmental feature of clear cell renal cell carcinoma revealed by m6A and lactylation modification-related genes (2023-08-11)

    期刊:Frontiers in Immunology

    DOI:10.3389/fimmu.2023.1225023

    影响因子 :7.3

    引用产品: HK-2 细胞 ,  ACHN 细胞

  • Discovery and Design of Novel Cyclic Peptides as Specific Inhibitors Targeting CCN2 and Disrupting CCN2/EGFR Interaction for Kidney Fibrosis Treatment (2023-06-06)

    期刊:JOURNAL OF MEDICINAL CHEMISTRY

    DOI:10.1021/acs.jmedchem.3c00594

    影响因子 :7.3

    引用产品: HK-2 细胞

  • Hyperoside mediates protection from diabetes kidney disease by regulating ROS-ERK signaling pathway and pyroptosis (2023-08-30)

    期刊:PHYTOTHERAPY RESEARCH

    DOI:10.1002/ptr.7993

    影响因子 :7.2

    引用产品: HK-2 细胞

  • Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway (2023-07-25)

    期刊:Cell Death Discovery

    DOI:10.1038/s41420-023-01564-1

    影响因子 :7.0

    引用产品: HK-2 细胞

  • Seratrodast platinum(IV) hybrids efficiently inhibit cancer-related thrombosis and metastasis phenotype in vitro and in vivo (2023-09-18)

    期刊:Inorganic Chemistry Frontiers

    DOI:10.1039/D3QI01328F

    影响因子 :7.0

    引用产品: A549 [A-549] 细胞 ,  A2780 细胞 ,  Hep G2 细胞 ,  AsPC-1 细胞 ,  HCT 116 细胞 ,  HK-2 细胞

  • Human bone marrow mesenchymal stem cell-derived extracellular vesicles reduce inflammation and pyroptosis in acute kidney injury via miR-223-3p/HDAC2/SNRK (2023-01-14)

    期刊:INFLAMMATION RESEARCH

    DOI:10.1007/s00011-022-01653-4

    影响因子 :6.7

    引用产品: 人骨髓间充质干细胞 ,  HK-2 细胞

  • Systemic mutation of Ncf1 ameliorates obstruction-induced renal fibrosis while macrophage-rescued NCF1 further alleviates renal fibrosis (2023-06-30)

    期刊:ANTIOXIDANTS & REDOX SIGNALING

    DOI:10.1089/ars.2022.0195

    影响因子 :6.6

    引用产品: HK-2 细胞

  • Novel Role of Hemeoxygenase-1 in Phthalate-Induced Renal Proximal Tubule Cell Ferroptosis (2023-01-25)

    期刊:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

    DOI:10.1021/acs.jafc.2c07762

    影响因子 :6.1

    引用产品: HK-2 细胞 ,  MEM (含NEAA) 培养基

  • Ochratoxin A Induces Renal Cell Ferroptosis by Disrupting Iron Homeostasis and Increasing ROS (2023-12-22)

    期刊:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

    DOI:10.1021/acs.jafc.3c04495

    影响因子 :6.1

    引用产品: HK-2 细胞 ,  青霉素-链霉素溶液 (双抗),100×

  • Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota (2023-01-17)

    期刊:Food & Function

    DOI:10.1039/D2FO03332A

    影响因子 :6.1

    引用产品: HK-2 细胞 ,  MEM (含NEAA) 培养基

  • Identification of the H3K36me3 reader LEDGF/p75 in the pancancer landscape and functional exploration in clear cell renal cell carcinoma (2023-08-26)

    期刊:Computational and Structural Biotechnology Journal

    DOI:10.1016/j.csbj.2023.08.023

    影响因子 :6.0

    引用产品: Caki-1 细胞 ,  786-O [786-0] 细胞 ,  A-498 细胞 ,  HK-2 细胞

  • Polystyrene nanoplastics induce apoptosis of human kidney proximal tubular epithelial cells via oxidative stress and MAPK signaling pathways (2023-10-04)

    期刊:ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

    DOI:10.1007/s11356-023-30155-x

    影响因子 :5.8

    引用产品: HK-2 细胞

  • CIRP attenuates acute kidney injury after hypothermic cardiovascular surgery by inhibiting PHD3/HIF-1α-mediated ROS-TGF-β1/p38 MAPK activation and mitochondrial apoptotic pathways (2023-05-01)

    期刊:MOLECULAR MEDICINE

    DOI:10.1186/s10020-023-00655-0

    影响因子 :5.7

    引用产品: HK-2 细胞

  • Exosome-mediated crosstalk between epithelial cells amplifies the cell injury cascade in CaOx stone formation (2023-02-28)

    期刊:Journal of Biological Engineering

    DOI:10.1186/s13036-023-00324-0

    影响因子 :5.6

    引用产品: HK-2 细胞

  • LMCD1 is involved in tubulointerstitial inflammation in the early phase of renal fibrosis by promoting NFATc1-mediated NLRP3 activation (2023-06-11)

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2023.110362

    影响因子 :5.6

    引用产品: HK-2 细胞

  • Melatonin alleviates intrarenal CaOx crystals deposition through inhibiting LPS-induced non-canonical inflammasome-mediated renal tubular epithelial cells pyroptosis (2023-08-24)

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2023.110796

    影响因子 :5.6

    引用产品: HK-2 细胞 ,  HK-2细胞专用培养基

  • Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro (2023-01-26)

    期刊:Frontiers in Endocrinology

    DOI:10.3389/fendo.2022.1009507

    影响因子 :5.2

    引用产品: HK-2 细胞

  • Establishing a prognostic model based on five starvation-related long non-coding RNAs for clear cell renal cell carcinoma (2023-06-20)

    期刊:Aging-US

    DOI:10.18632/aging.204816

    影响因子 :5.2

    引用产品: 786-O [786-0] 细胞 ,  Caki-1 细胞 ,  HK-2 细胞

  • Ferroptosis in calcium oxalate kidney stone formation and the possible regulatory mechanism of ANKRD1 (2023-03-11)

    期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

    DOI:10.1016/j.bbamcr.2023.119452

    影响因子 :5.1

    引用产品: HK-2 细胞 ,  HK-2细胞专用培养基

  • LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1–Induced Epithelial–Mesenchymal Transition in Human Kidney 2 Cells (2023-01-10)

    期刊:LABORATORY INVESTIGATION

    DOI:10.1016/j.labinv.2022.100016

    影响因子 :5.0

    引用产品: HK-2 细胞

  • Identification of a novel 5-methylcytosine-related signature for prognostic prediction of kidney renal papillary cell carcinoma and a Putative target for drug repurposing (2023-07-29)

    期刊:Translational Oncology

    DOI:10.1016/j.tranon.2023.101741

    影响因子 :5.0

    引用产品: HK-2 细胞 ,  Caki-2 细胞

  • FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells (2023-09-02)

    期刊:Journal of Translational Internal Medicine

    DOI:10.2478/jtim-2023-0105

    影响因子 :4.9

    引用产品: HK-2 细胞 ,  特级胎牛血清

  • Glycyrrhizic acid improves tacrolimus-induced renal injury by regulating autophagy (2023-01-23)

    期刊:FASEB JOURNAL

    DOI:10.1096/fj.202201409RR

    影响因子 :4.8

    引用产品: HK-2 细胞

  • Expression of gasdermin D in clear cell renal cell carcinoma and its effect on its biological function (2023-07-06)

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2023.1163714

    影响因子 :4.7

    引用产品: 786-O [786-0] 细胞 ,  769-P 细胞 ,  HK-2 细胞

  • Tumor-associated M2 macrophages in the immune microenvironment influence the progression of renal clear cell carcinoma by regulating M2 macrophage-associated genes (2023-06-08)

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2023.1157861

    影响因子 :4.7

    引用产品: 786-O [786-0] 细胞 ,  HK-2 细胞 ,  THP-1 细胞 ,  特级胎牛血清

  • A pan-cancer analysis of DDR1 in prognostic signature and tumor immunity, drug resistance (2023-04-08)

    期刊:Scientific Reports

    DOI:10.1038/s41598-023-27975-9

    影响因子 :4.6

    引用产品: HK-2 细胞 ,  786-O [786-0] 细胞 ,  Caki-1 细胞 ,  SV-HUC-1 细胞 ,  T24 [T-24] 细胞 ,  5637 细胞 ,  RWPE-1 细胞 ,  PC-3 细胞 ,  DU 145 细胞 ,  DMEM高糖 培养基 ,  RPMI-1640 培养基 ,  Ham's F-12K 培养基 ,  人前列腺上皮细胞完全培养基

  • Protease-Activated Receptor-2 and Phospholipid Metabolism Analysis in Hyperuricemia-Induced Renal Injury (2023-07-13)

    期刊:MEDIATORS OF INFLAMMATION

    DOI:10.1155/2023/5007488

    影响因子 :4.6

    引用产品: HK-2 细胞

  • Ganoderic Acid A and Its Amide Derivatives as Potential Anti-Cancer Agents by Regulating the p53-MDM2 Pathway: Synthesis and Biological Evaluation (2023-03-04)

    期刊:MOLECULES

    DOI:10.3390/molecules28052374

    影响因子 :4.6

    引用产品: MCF7 [MCF-7] 细胞 ,  Hep G2 细胞 ,  SJSA-1 细胞 ,  HK-2 细胞

  • Norcantharidin-Encapsulated C60-Modified Nanomicelles: A Potential Approach to Mitigate Cytotoxicity in Renal Cells and Simultaneously Enhance Anti-Tumor Activity in Hepatocellular Carcinoma Cells (2023-11-15)

    期刊:MOLECULES

    DOI:10.3390/molecules28227609

    影响因子 :4.6

    引用产品: HK-2 细胞

  • Focusing on the Abnormal Events of NPC1, NPC2, and NPC1L1 in Pan-Cancer and Further Constructing LUAD and KICH Prediction Models (2023-12-18)

    期刊:JOURNAL OF PROTEOME RESEARCH

    DOI:10.1021/acs.jproteome.3c00655

    影响因子 :4.4

    引用产品: A549 [A-549] 细胞 ,  NCI-H1299 细胞 ,  HK-2 细胞 ,  A-498 细胞 ,  MEM 培养基 ,  RPMI-1640 培养基 ,  Ham's F-12K 培养基

  • The induction of ferroptosis by KLF11/NCOA4 axis: the inhibitory role in clear cell renal cell carcinoma (2023-08-29)

    期刊:Human Cell

    DOI:10.1007/s13577-023-00973-9

    影响因子 :4.3

    引用产品: HK-2 细胞 ,  769-P 细胞 ,  McCoy's 5A 培养基

  • Silencing of adipocyte enhancer-binding protein 1 (AEBP1) alleviates renal fibrosis in vivo and in vitro via inhibition of the β-catenin signaling pathway (2023-02-04)

    期刊:Human Cell

    DOI:10.1007/s13577-023-00859-w

    影响因子 :4.3

    引用产品: HK-2 细胞 ,  特级胎牛血清

  • Zinc Oxide Nanoparticles Induce Renal Injury by Initiating Oxidative Stress, Mitochondrial Damage and Apoptosis in Renal Tubular Epithelial Cells (2023-04-29)

    期刊:BIOLOGICAL TRACE ELEMENT RESEARCH

    DOI:10.1007/s12011-023-03683-3

    影响因子 :3.9

    引用产品: HK-2 细胞

  • Mixed-ligand copper(II) hydrazone complexes: Synthesis, structure, and anti-lung cancer properties (2023-01-19)

    期刊:JOURNAL OF MOLECULAR STRUCTURE

    DOI:10.1016/j.molstruc.2023.134986

    影响因子 :3.8

    引用产品: A549 [A-549] 细胞 ,  A549/DDP 细胞 ,  HK-2 细胞

  • Identification of an unrecognized circRNA associated with development of renal fibrosis (2023-01-04)

    期刊:Frontiers in Genetics

    DOI:10.3389/fgene.2022.964840

    影响因子 :3.7

    引用产品: HK-2 细胞

  • Nephropathy Is Aggravated by Fatty Acids in Diabetic Kidney Disease through Tubular Epithelial Cell Necroptosis and Is Alleviated by an RIPK-1 Inhibitor (2023-03-17)

    期刊:Kidney Diseases

    DOI:10.1159/000529995

    影响因子 :3.7

    引用产品: HK-2 细胞

  • Based on disulfidptosis, revealing the prognostic and immunological characteristics of renal cell carcinoma with tumor thrombus of vena cava and identifying potential therapeutic target AJAP1 (2023-05-29)

    期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

    DOI:10.1007/s00432-023-04877-x

    影响因子 :3.6

    引用产品: HK-2 细胞 ,  Caki-1 细胞 ,  OS-RC-2 细胞

  • Circ_0006944 aggravates LPS-induced HK2 cell injury via modulating miR-205-5p/UBL4A pathway (2023-11-22)

    期刊:AUTOIMMUNITY

    DOI:10.1080/08916934.2023.2276066

    影响因子 :3.5

    引用产品: HK-2 细胞

  • A latent reversible ratiometric optical pH sensing probe based on phenylboronic acid for alkaline pH detection and applications in test paper and alkalotic HK-2 cells (2023-05-10)

    期刊:NEW JOURNAL OF CHEMISTRY

    DOI:10.1039/D3NJ01398G

    影响因子 :3.3

    引用产品: HK-2 细胞

  • Knockdown of KLF5 ameliorates renal fibrosis in MRL/lpr mice via inhibition of MX1 transcription (2023-07-27)

    期刊:Immunity Inflammation and Disease

    DOI:10.1002/iid3.937

    影响因子 :3.2

    引用产品: HK-2 细胞

  • Circ_0068087 knockdown attenuates high-glucose-induced human tubular epithelial cell injury in a microribonucleic acid/progestin and adipoQ receptor 3-dependent manner in diabetic nephropathy (2023-11-20)

    期刊:Journal of Diabetes Investigation

    DOI:10.1111/jdi.14107

    影响因子 :3.2

    引用产品: HK-2 细胞 ,  MEM (含NEAA) 培养基

  • CircUSP42 ameliorates LPS-induced human renal epithelial cells in vitro by regulating the miR-182-5p/DUSP1 axis (2023-10-17)

    期刊:SHOCK

    DOI:10.1097/SHK.0000000000002229

    影响因子 :3.1

    引用产品: HK-2 细胞

  • Exosomal circVMA21 derived from adipose-derived stem cells alleviates sepsis-induced acute kidney injury by targeting miR-16-5p (2023-07-12)

    期刊:SHOCK

    DOI:10.1097/SHK.0000000000002179

    影响因子 :3.1

    引用产品: 小鼠脂肪间充质干细胞成骨诱导分化培养基 ,  小鼠脂肪间充质干细胞成脂诱导分化培养基 ,  HK-2 细胞

  • CircNRIP1 KNOCKDOWN ALLEVIATES LIPOPOLYSACCHARIDE-INDUCED HUMAN KIDNEY 2 CELL APOPTOSIS AND INFLAMMATION THROUGH miR-339-5p/OXSR1 PATHWAY (2023-03-26)

    期刊:SHOCK

    DOI:10.1097/SHK.0000000000002057

    影响因子 :3.1

    引用产品: HK-2 细胞

  • MicroRNA-192-5p downregulates Fat Mass and Obesity-associated Protein to aggravate renal ischemia/reperfusion injury (2023-12-22)

    期刊:RENAL FAILURE

    DOI:10.1080/0886022X.2023.2285869

    影响因子 :3.0

    引用产品: HK-2 细胞

  • Exploratory metabolomic analysis based on UHPLC-Q-TOF-MS/MS to study hypoxia-reoxygenation energy metabolic alterations in HK-2 cells (2023-05-29)

    期刊:RENAL FAILURE

    DOI:10.1080/0886022X.2023.2186715

    影响因子 :3.0

    引用产品: HK-2 细胞

  • TIGAR protects against adenine-induced ferroptosis in human proximal tubular epithelial cells by activating the mTOR/S6KP70 axis (2023-05-04)

    期刊:NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

    DOI:10.1080/01635581.2023.2203353

    影响因子 :2.9

    引用产品: HK-2 细胞

  • Anemonin inhibits sepsis-induced acute kidney injury via mitigating inflammation and oxidative stress (2023-08-17)

    期刊:BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

    DOI:10.1002/bab.2504

    影响因子 :2.8

    引用产品: HK-2 细胞

  • Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress (2023-07-20)

    期刊:BMC Molecular and Cell Biology

    DOI:10.1186/s12860-023-00485-2

    影响因子 :2.8

    引用产品: HK-2 细胞

  • Liuwei Dihuang Decoction Drug-containing Serum Attenuates Transforming Growth Factor-β1-induced Epithelial-mesenchymal Transition in HK-2 Cells by Inhibiting NF-κB/Snail Signaling Pathway (2023-03-24)

    期刊:CURRENT PHARMACEUTICAL BIOTECHNOLOGY

    DOI:10.2174/1389201024666230228100718

    影响因子 :2.8

    引用产品: HK-2 细胞 ,  DMEM高糖 培养基 ,  特级胎牛血清

  • Shen Qi Wan-Containing Serum Alleviates Renal Interstitial Fibrosis via Restraining Notch1-Mediated Epithelial-Mesenchymal Transition (2023-02-06)

    期刊:Evidence-based Complementary and Alternative Medicine

    DOI:10.1155/2023/3352353

    影响因子 :2.7

    引用产品: HK-2 细胞 ,  HK-2细胞专用培养基

  • Circ_0068087 Promotes High Glucose-Induced Human Renal Tubular Cell Injury through Regulating miR-106a-5p/ROCK2 Pathway (2023-04-20)

    期刊:NEPHRON

    DOI:10.1159/000525440

    影响因子 :2.5

    引用产品: HK-2 细胞 ,  MEM 培养基

  • Resveratrol Inhibits circ_0074371-related Pathway to Alleviate Sepsis-induced Acute Kidney Injury (2023-09-20)

    期刊:BIOCHEMICAL GENETICS

    DOI:10.1007/s10528-023-10517-3

    影响因子 :2.4

    引用产品: HK-2 细胞

  • Coptisine mitigates diabetic nephropathy via repressing the NRLP3 inflammasome (2023-05-11)

    期刊:Open Life Sciences

    DOI:10.1515/biol-2022-0568

    影响因子 :2.2

    引用产品: HK-2 细胞 ,  特级胎牛血清

  • Ramelteon attenuates renal ischemia and reperfusion injury through reducing mitochondrial fission and fusion and inflammation (2023-12-21)

    期刊:Translational Andrology and Urology

    DOI:10.21037/tau-23-543

    影响因子 :2.0

    引用产品: HK-2 细胞 ,  MEM (含NEAA) 培养基

  • GDF11, a target of miR-32-5p, suppresses high-glucose-induced mitochondrial dysfunction and apoptosis in HK-2 cells through PI3K/AKT signaling activation (2023-02-07)

    期刊:INTERNATIONAL UROLOGY AND NEPHROLOGY

    DOI:10.1007/s11255-023-03495-3

    影响因子 :2.0

    引用产品: HK-2 细胞

  • The damage mechanism of uranium(VI) to HK-2 cells (2023-03-01)

    期刊:JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY

    DOI:10.1007/s10967-023-08843-2

    影响因子 :1.6

    引用产品: HK-2 细胞

  • A Water-Soluble AIEgen for Noninvasive Diagnosis of Kidney Fibrosis via SWIR Fluorescence and Photoacoustic Imaging (2022-10-12)

    期刊:ADVANCED MATERIALS

    DOI:10.1002/adma.202206643

    影响因子 :32.1

    引用产品: HK-2 细胞

  • Adropin Carried by Reactive Oxygen Species-Responsive Nanocapsules Ameliorates Renal Lipid Toxicity in Diabetic Mice (2022-08-11)

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.2c06957

    影响因子 :10.4

    引用产品: HK-2 细胞

  • Protective effects of Polygonatum kingianum polysaccharides and aqueous extract on uranium-induced toxicity in human kidney (HK-2) cells (2001-02-20)

    期刊:International Journal Of Biological Macromolecules

    DOI:10.1016/j.ijbiomac.2022.01.043

    影响因子 :8.2

    引用产品: HK-2 细胞

  • 6-Shogaol Exhibits a Promoting Effect with Tax via Binding HSP60 in Non-Small-Cell Lung Cancer (2022-11-19)

    期刊:Cells

    DOI:10.3390/cells11223678

    影响因子 :7.7

    引用产品: A-375 细胞 ,  A549 [A-549] 细胞 ,  H8 细胞 ,  U251 细胞 ,  3T3-L1 细胞 ,  PANC-1 细胞 ,  TSSCA 细胞 ,  HK-2 细胞 ,  DMEM高糖 培养基 ,  RPMI-1640 培养基

  • Dioscin Protects against Cisplatin-Induced Acute Kidney Injury by Reducing Ferroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling (2022-12-11)

    期刊:Antioxidants

    DOI:10.3390/antiox11122443

    影响因子 :7.7

    引用产品: HK-2 细胞

  • Aluminum exposure induces nephrotoxicity via fibrosis and apoptosis through the TGF-β1/Smads pathway in vivo and in vitro (2022-12-13)

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2022.114422

    影响因子 :7.1

    引用产品: HK-2 细胞

  • Tumor Cell-Derived Exosomal circ-PRKCI Promotes Proliferation of Renal Cell Carcinoma via Regulating miR-545-3p/CCND1 Axis (2022-12-25)

    期刊:Cancers

    DOI:10.3390/cancers15010123

    影响因子 :6.6

    引用产品: 786-O [786-0] 细胞 ,  ACHN 细胞 ,  Caki-1 细胞 ,  769-P 细胞 ,  HK-2 细胞

  • Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis. (2022-09-21)

    期刊:Frontiers in Pharmacology

    DOI:10.3389/fphar.2022.938134

    影响因子 :6.0

    引用产品: SV-HUC-1 细胞 ,  T24 [T-24] 细胞 ,  5637 细胞 ,  HK-2 细胞 ,  786-O [786-0] 细胞 ,  Caki-1 细胞 ,  RWPE-1 细胞 ,  PC-3 细胞 ,  DU 145 细胞 ,  Ham's F-12K 培养基 ,  DMEM高糖 培养基 ,  人前列腺上皮细胞完全培养基 ,  RPMI-1640 培养基

  • Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway (2022-10-07)

    期刊:Frontiers in Pharmacology

    DOI:10.3389/fphar.2022.970616

    影响因子 :6.0

    引用产品: HK-2 细胞

  • T-2 Toxin Induces Kidney Fibrosis via the mtROS-NLRP3-Wnt/β-Catenin Axis (2022-10-14)

    期刊:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

    DOI:10.1021/acs.jafc.2c05816

    影响因子 :5.9

    引用产品: HK-2 细胞 ,  青霉素-链霉素溶液 (双抗),100×

  • Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA‑binding protein RBFOX1 in this disease (2001-02-20)

    期刊:International Journal Of Molecular Medicine

    DOI:10.3892/ijmm.2022.5087

    影响因子 :5.4

    引用产品: HK-2 细胞

  • Up-regulation of the human-specific CHRFAM7A gene protects against renal fibrosis in mice with obstructive nephropathy (2022-12-07)

    期刊:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

    DOI:10.1111/jcmm.17630

    影响因子 :5.3

    引用产品: HK-2 细胞

  • Chronic intermittent hypoxia induces the pyroptosis of renal tubular epithelial cells by activating the NLRP3 inflammasome (2003-02-20)

    期刊:Bioengineered

    DOI:10.1080/21655979.2022.2047394

    影响因子 :4.9

    引用产品: HK-2 细胞

  • Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma (2022-02-16)

    期刊:Journal of Inflammation Research

    DOI:10.2147/JIR.S347732

    影响因子 :4.5

    引用产品: Caki-1 细胞 ,  769-P 细胞 ,  786-O [786-0] 细胞 ,  ACHN 细胞 ,  HK-2 细胞

  • Role of (Pro)Renin Receptor in Cyclosporin A-Induced Nephropathy (2001-02-20)

    期刊:AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY

    DOI:10.1152/ajprenal.00332.2021

    影响因子 :4.2

    引用产品: HK-2 细胞

  • Knockdown of circ_0003928 ameliorates high glucose-induced dysfunction of human tubular epithelial cells through the miR-506-3p/ HDAC4 pathway in diabetic nephropathy (2004-02-20)

    期刊:EUROPEAN JOURNAL OF MEDICAL RESEARCH

    DOI:10.1186/s40001-022-00679-y

    影响因子 :4.2

    引用产品: HK-2 细胞

  • Downregulation of circ-ZNF644 alleviates LPS-induced HK2 cell injury via miR-335-5p/HIPK1 axis (2022-09-02)

    期刊:ENVIRONMENTAL TOXICOLOGY

    DOI:10.1002/tox.23642

    影响因子 :4.1

    引用产品: HK-2 细胞 ,  MEM 培养基

  • CircZNF644 aggravates lipopolysaccharide-induced HK-2 cell impairment via the miR-140-5p/MLKL axis (2022-08-17)

    期刊:JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

    DOI:10.1007/s10863-022-09946-3

    影响因子 :3.9

    引用产品: HK-2 细胞 ,  MEM 培养基 ,  青霉素-链霉素溶液 (双抗),100× ,  特级胎牛血清

  • Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate (2004-02-20)

    期刊:CELL STRESS & CHAPERONES

    DOI:10.1007/s12192-022-01266-0

    影响因子 :3.8

    引用产品: 293 [HEK-293] 细胞 ,  HK-2 细胞

  • Identifying the mechanisms and molecular targets of Hongjingtian injection on treatment of TGFβ1-induced HK-2 cells: coupling network pharmacology with experimental verification (2022-12-01)

    期刊:Annals of Translational Medicine

    DOI:10.21037/atm-22-5035

    影响因子 :3.6

    引用产品: HK-2 细胞

  • High-glucose induced toxicity in HK-2 cells can be alleviated by inhibition of miRNA-320c (2022-08-15)

    期刊:RENAL FAILURE

    DOI:10.1080/0886022X.2022.2106874

    影响因子 :3.2

    引用产品: HK-2 细胞

  • Silencing circ_0074371 inhibits the progression of sepsis-induced acute kidney injury by regulating miR-330-5p/ELK1 axis (2022-08-22)

    期刊:MAMMALIAN GENOME

    DOI:10.1007/s00335-022-09961-0

    影响因子 :3.2

    引用产品: HK-2 细胞 ,  青霉素-链霉素溶液 (双抗),100×

  • High Glucose-Induced Human Kidney Cell Apoptosis and Inflammatory Injury Are Alleviated by Circ_0008529 Knockdown via Circ_0008529-Mediated miR-485-5p/WNT2B Signaling (2022-08-01)

    期刊:APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

    DOI:10.1007/s12010-022-04088-z

    影响因子 :3.1

    引用产品: HK-2 细胞

  • Forkhead box A2-mediated lncRNA SOX2OT up-regulation alleviates oxidative stress and apoptosis of renal tubular epithelial cells by promoting SIRT1 expression in diabetic nephropathy (2022-12-28)

    期刊:NEPHROLOGY

    DOI:10.1111/nep.14139

    影响因子 :2.4

    引用产品: HK-2 细胞

  • LncRNA NEAT1 knockdown ameliorates LPS-induced human kidney injury by mediating the miR-330-5p/FOXO3 axis (2004-02-20)

    期刊:INTERNATIONAL UROLOGY AND NEPHROLOGY

    DOI:10.1007/s11255-022-03179-4

    影响因子 :2.0

    引用产品: HK-2 细胞

  • Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression (2022-11-30)

    期刊:TRANSPLANT IMMUNOLOGY

    DOI:10.1016/j.trim.2022.101764

    影响因子 :2.0

    引用产品: HK-2 细胞 ,  OS-RC-2 细胞 ,  ACHN 细胞 ,  786-O [786-0] 细胞

  • A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy (2007-01-20)

    期刊:Journal Of Colloid And Interface Science

    DOI:10.1016/j.jcis.2021.07.080

    影响因子 :9.9

    引用产品: HK-2 细胞

  • Liproxstatin-1 attenuates unilateral ureteral obstruction-induced renal fibrosis by inhibiting renal tubular epithelial cells ferroptosis (2009-01-20)

    期刊:Cell Death & Disease

    DOI:10.1038/s41419-021-04137-1

    影响因子 :9.0

    引用产品: HK-2 细胞

  • A nanosensor for precise discrimination of nephrotoxic drug mechanisms via dynamic fluorescence fingerprint strategy (2003-01-20)

    期刊:Analytica Chimica Acta

    DOI:10.1016/j.aca.2021.338447

    影响因子 :6.2

    引用产品: MEM非必需氨基酸溶液 (NEAA),100× ,  HK-2 细胞

  • Senkyunolide I alleviates renal Ischemia-Reperfusion injury by inhibiting oxidative stress, endoplasmic reticulum stress and apoptosis (2011-01-20)

    期刊:International Immunopharmacology

    DOI:10.1016/j.intimp.2021.108393

    影响因子 :5.6

    引用产品: HK-2 细胞 ,  MEM (含NEAA) 培养基 ,  青霉素-链霉素溶液 (双抗),100× ,  特级胎牛血清

  • Migration of Human Renal Tubular Epithelial Cells in Response to Physiological Electric Signals (2009-01-20)

    期刊:Frontiers in Cell and Developmental Biology

    DOI:10.3389/fcell.2021.724012

    影响因子 :5.5

    引用产品: HK-2 细胞 ,  293 [HEK-293] 细胞

  • Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway (2007-01-20)

    期刊:Journal Of Ethnopharmacology

    DOI:10.1016/j.jep.2021.114414

    影响因子 :5.4

    引用产品: HK-2 细胞

  • MicroRNA 181a-2-3p Alleviates the Apoptosis of Renal Tubular Epithelial Cells via Targeting GJB2 in Sepsis-Induced Acute Kidney Injury | Molecular and Cellular Biology (2006-01-20)

    期刊:Molecular And Cellular Biology

    DOI:10.1128/MCB.00016-21

    影响因子 :5.3

    引用产品: HK-2 细胞

  • Downregulation of IRF2 Alleviates Sepsis-Related Acute Kidney Injury in vitro and in vivo (2012-01-20)

    期刊:Drug Design Development and Therapy

    DOI:10.2147/DDDT.S334518

    影响因子 :4.8

    引用产品: HK-2 细胞

  • Knockdown of circ-FANCA alleviates LPS-induced HK2 cell injury via targeting miR-93-5p/OXSR1 axis in septic acute kidney injury (2001-01-20)

    期刊:Diabetology & Metabolic Syndrome

    DOI:10.1186/s13098-021-00625-8

    影响因子 :4.8

    引用产品: HK-2 细胞 ,  MEM (含NEAA) 培养基

  • Anti-Malignant Ascites Effect of Total Diterpenoids from Euphorbiae ebracteolatae Radix Is Attributable to Alterations of Aquaporins via Inhibiting PKC Activity in the Kidney (2002-01-20)

    期刊:Molecules

    DOI:10.3390/molecules26040942

    影响因子 :4.6

    引用产品: 特级胎牛血清 ,  HK-2 细胞

  • Overexpression of TOLLIP Protects against Acute Kidney Injury after Paraquat Intoxication through Inhibiting NLRP3 Inflammasome Activation Modulated by Toll-Like Receptor 2/4 Signaling (2007-01-20)

    期刊:Mediators Of Inflammation

    DOI:10.1155/2021/5571272

    影响因子 :4.6

    引用产品: HK-2 细胞

  • Metabolomics analysis underlay mechanisms in the renal impairment of mice caused by combination of aflatoxin M1 and ochratoxin A (2006-01-20)

    期刊:Toxicology

    DOI:10.1016/j.tox.2021.152835

    影响因子 :4.5

    引用产品: HK-2 细胞

  • Loganin Attenuates Septic Acute Renal Injury with the Participation of AKT and Nrf2/HO-1 Signaling Pathways (2002-01-20)

    期刊:Drug Design Development and Therapy

    DOI:10.2147/DDDT.S294266

    影响因子 :4.3

    引用产品: HK-2 细胞

  • The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi-omics study (2011-01-20)

    期刊:Cancer Medicine

    DOI:10.1002/cam4.4395

    影响因子 :4.0

    引用产品: 786-O [786-0] 细胞 ,  A-498 细胞 ,  HK-2 细胞

  • HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma (2002-01-20)

    期刊:Cell Biology International

    DOI:10.1002/cbin.11568

    影响因子 :3.9

    引用产品: HK-2 细胞 ,  A-498 细胞 ,  786-O [786-0] 细胞 ,  Caki-1 细胞

  • CircVMA21 ameliorates lipopolysaccharide (LPS)-induced HK-2 cell injury depending on the regulation of miR-7-5p/PPARA (2012-01-20)

    期刊:Autoimmunity

    DOI:10.1080/08916934.2021.2012764

    影响因子 :3.5

    引用产品: HK-2 细胞 ,  青霉素-链霉素溶液 (双抗),100× ,  特级胎牛血清

  • Circular RNA circ_0068,888 protects against lipopolysaccharide-induced HK-2 cell injury via sponging microRNA-21–5p (2002-01-20)

    期刊:Biochemical And Biohysical Research Communicattons

    DOI:10.1016/j.bbrc.2020.12.018

    影响因子 :3.1

    引用产品: HK-2 细胞

  • LncRNA NKILA knockdown promotes cell viability and represses cell apoptosis, autophagy and inflammation in lipopolysaccharide-induced sepsis model by regulating miR-140-5p/CLDN2 axis (2004-01-20)

    期刊:Biochemical and Biophysical Research Communications

    DOI:10.1016/j.bbrc.2021.04.074

    影响因子 :3.1

    引用产品: 293T [HEK-293T] 细胞 ,  HK-2 细胞

  • Aldosterone Induces the Proliferation of Renal Tubular Epithelial Cells In Vivo but Not In Vitro (2007-01-20)

    期刊:Journal Of The Renin-Angiotensin-Aldosterone System

    DOI:10.1155/2021/9943848

    影响因子 :2.9

    引用产品: HK-2 细胞

  • Identification of hub genes and transcription factor-miRNA-mRNA pathways in mice and human renal ischemia-reperfusion injury (2010-01-20)

    期刊:PeerJ

    DOI:10.7717/peerj.12375

    影响因子 :2.7

    引用产品: HK-2 细胞

  • Thioredoxin relieves lipopolysaccharide‑induced acute kidney injury in mice by reducing inflammation, oxidative stress and apoptosis (2004-01-20)

    期刊:Experimental and Therapeutic Medicine

    DOI:10.3892/etm.2021.10061

    影响因子 :2.7

    引用产品: HK-2 细胞

  • Long Non-Coding RNA CASC2 Overexpression Ameliorates Sepsis-Associated Acute Kidney Injury by Regulating MiR-545-3p/PPARA axis (2005-01-20)

    期刊:Journal of Surgical Research

    DOI:10.1016/j.jss.2021.03.047

    影响因子 :2.2

    引用产品: HK-2 细胞 ,  293 [HEK-293] 细胞

  • Advanced Oxidation Protein Product Promotes Oxidative Accentuation in Renal Epithelial Cells via the Soluble (Pro)renin Receptor-Mediated Intrarenal Renin-Angiotensin System and Nox4-H2O2 Signaling (2011-01-20)

    期刊:Oxidative Medicine and Cellular Longevity

    DOI:10.1155/2021/5710440

    影响因子 :0.0

    引用产品: HK-2 细胞 ,  DMEM/F12 培养基 ,  特级胎牛血清 ,  青霉素-链霉素溶液 (双抗),100×

  • ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway (2008-00-20)

    期刊:Cell Death & Disease

    DOI:10.1038/s41419-020-02912-0

    影响因子 :9.0

    引用产品: HK-2 细胞

  • Involvement of miR‐27a‐3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress (2007-00-20)

    期刊:Journal Of Cellular Physiology

    DOI:10.1002/jcp.29951

    影响因子 :5.6

    引用产品: HK-2 细胞

  • Sodium butyrate ameliorates deoxycorticosterone acetate/salt-induced hypertension and renal damage by inhibiting the MR/SGK1 pathway (2009-00-20)

    期刊:Hypertension Research

    DOI:10.1038/s41440-020-00548-3

    影响因子 :5.4

    引用产品: HK-2 细胞 ,  青霉素-链霉素溶液 (双抗),100×

  • Soluble (pro)renin receptor promotes the fibrotic response in renal proximal tubule epithelial cells in vitro via the Akt/β-catenin/Snail signaling pathway (2011-00-20)

    期刊:American Journal Of Physiology-Renal Physiology

    DOI:10.1152/ajprenal.00197.2020

    影响因子 :4.2

    引用产品: HK-2 细胞

  • Rapid and sensitive detection of NGAL for the prediction of acute kidney injury via a polydopamine nanosphere/aptamer nanocomplex coupled with DNase I-assisted recycling amplification (2004-00-20)

    期刊:Analyst

    DOI:10.1039/D0AN00474J

    影响因子 :4.2

    引用产品: HK-2 细胞

  • δ‐Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β‐catenin nuclear localization and activating its downstream target genes (2001-00-20)

    期刊:Cancer Medicine

    DOI:10.1002/cam4.2857

    影响因子 :4.0

    引用产品: HK-2 细胞 ,  A-498 细胞 ,  ACHN 细胞 ,  786-O [786-0] 细胞

  • Hydroxytyrosol inhibits apoptosis in ischemia/reperfusion-induced acute kidney injury via activating Sonic Hedgehog signaling pathway (2012-00-20)

    期刊:European Review for Medical and Pharmacological Sciences

    DOI:10.26355/eurrev_202012_24032

    影响因子 :3.8

    引用产品: HK-2 细胞

  • Comprehensive analysis of the HOXA gene family identifes HOXA13as a novel oncogenic gene in kidney renal clear cell carcinoma (2005-00-20)

    期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

    DOI:10.1007/s00432-020-03259-x

    影响因子 :3.6

    引用产品: 786-O [786-0] 细胞 ,  Caki-1 细胞 ,  A-498 细胞 ,  HK-2 细胞

  • MiR-32-5p knockdown inhibits epithelial to mesenchymal transition and renal fibrosis by targeting SMAD7 in diabetic nephropathy: (2009-00-20)

    期刊:Human & Experimental Toxicology

    DOI:10.1177/0960327120952157

    影响因子 :2.8

    引用产品: HK-2 细胞

  • Efficacy of Obcordata A from Aspidopterys obcordata on Kidney Stones by Inhibiting NOX4 Expression (2003-09-20)

    期刊:Molecules

    DOI:10.3390/molecules24101957

    影响因子 :4.6

    引用产品: HK-2 细胞

  • Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation (2019-11-21)

    期刊:Yonsei Med J

    DOI:10.3349/ymj.2019.60.12.1195

    影响因子 :2.4

    引用产品: HK-2 细胞

  • Rhodomyrtosone B, a membrane-targeting anti-MRSA natural acylgphloroglucinol from Rhodomyrtus tomentosa (2009-08-20)

    期刊:Journal Of Ethnopharmacology

    DOI:10.1016/j.jep.2018.09.011

    影响因子 :5.4

    引用产品: HK-2 细胞

  • (Pro)renin receptor mediates albumin-induced cellular responses: role of site-1 protease-derived soluble (pro)renin receptor in renal epithelial cells (2012-07-20)

    期刊:American Journal of Physiology-Cell Physiology

    DOI:10.1152/ajpcell.00006.2017

    影响因子 :5.5

    引用产品: HK-2 细胞

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