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产品概述
| 名称 | TM3 (小鼠睾丸间质细胞) (STR鉴定正确) |
| 别称 | TM-3 |
| 种属 | 小鼠 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:8 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 该细胞贴壁松散，操作时请尽量轻柔；换液时需预热培养基；收货如有大块脱落的细胞团，为正常现象，请按照收货注意事项处理。 |
| 背景描述 | TM3细胞在LH作用下cAMP产量升高，但对促卵泡激素没有响应。TM3细胞对LH的响应持续时间与血清批次有关；在LH存在下，TM3细胞可以代谢胆固醇。 |
| 年龄（性别） | 雄性；11-13天 |
| 组织来源 | 睾丸间质 |
| 细胞类型 | 自发永生化细胞 |
| 生物安全等级 | BSL-1 |
| 致瘤性 | No, The cells were not tumorigenic in immunosuppressed mice, but did form colonies in semisolid medium. |
| 受体表达情况 | Luteinizing hormone (LH); epidermal growth factor (EGF); androgen receptor, positive; estrogen receptor, positive; progesterone receptor, positive |
| 基因表达情况 | prostaglandin F2a |
| 保藏机构 | ATCC; CRL-1714 ECACC; 91060526 |
STR鉴定
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STR位点信息
18-3 18 6-7 15 5-5 12 X-1 24 1-2 17 7-1 25.2,26.2 8-1 13,16,17 1-1 16 19-2 9 15-3 20.3,22.3 12-1 16 6-4 16.3,18 4-2 19.3 3-2 13,14 2-1 16 13-1 16.2
11-2 15,18 17-2 15,16 -
STR鉴定图
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参考文献
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Anti-Cancer Potency of Copper-Doped Carbon Quantum Dots Against Breast Cancer Progression (2024-02-26)
作者：Mengqi Wang:1.Key Laboratory of Medical Cell Biology, Department of Achievement Transformation, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People's Republic of China. ; Shuting Lan:1.Key Laboratory of Medical Cell Biology, Department of Achievement Transformation, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People's Republic of China. ; Wenqi Zhang:1.Key Laboratory of Medical Cell Biology, Department of Achievement Transformation, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People's Republic of China. ; Qin Jin:1.Department of Pathology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People's Republic of China. ; Hua Du:1.Department of Pathology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People's Republic of China. ; Xiaomei Sun:1.Key Laboratory of Medical Cell Biology, Department of Achievement Transformation, Aff
期刊：Anti-Cancer Potency of Copper-Doped Carbon Quantum Dots Against Breast Cancer Progression
影响因子 ：8.0
引用产品： NRK-52E 细胞 , TM3 细胞 , MA-782细胞专用培养基 , TM3细胞专用培养基 , DMEM高糖完全培养基 (含10%FBS）
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Melatonin alleviates oxidative stress damage in mouse testes induced by bisphenol A (2024-02-19)
作者：Qi Qi:1.Center for Reproductive Medicine, Jilin Medical University, Jilin, China. ; 2.School of Medical Technology, Beihua University, Jilin, China. ; Jiaxin Yang:1.Center for Reproductive Medicine, Jilin Medical University, Jilin, China. ; Shuang Li:1.Center for Reproductive Medicine, Jilin Medical University, Jilin, China. ; 2.School of Medical Technology, Beihua University, Jilin, China. ; Jingjing Liu:1.Center for Reproductive Medicine, Jilin Medical University, Jilin, China. ; 2.School of Medical Technology, Beihua University, Jilin, China. ; Da Xu:1.Center for Reproductive Medicine, Jilin Medical University, Jilin, China. ; Guoqing Wang:1.School of Medical Technology, Beihua University, Jilin, China. ; Lei Feng:1.Center for Reproductive Medicine, Jilin Medical University, Jilin, China. ; Xiaoyan Pan:1.Center for Reproductive Medicine, Jilin Medical University, Jilin, China. ;
期刊：Melatonin alleviates oxidative stress damage in mouse testes induced by bisphenol A
DOI：10.3389/fcell.2024.1338828
影响因子 ：5.5
引用产品： TM3 细胞
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Toxic effects of Tripterygium glycoside tablets on the reproductive system of male rats by metabolomics, cytotoxicity, and molecular docking (2023-04-10)
作者：Jia-Chen Ge:1.School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, PR China. ; Qi Qian:1.School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, PR China. ; Yan-Hua Gao:1.School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, PR China. ; Yi-Fan Zhang:1.School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, PR China. ; Ying-Xuan Li:1.School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, PR China. ; Xu Wang:1.School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, PR China. ; Yan Fu:1.School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, PR China. ; Yu-Mei Ma:1.Department of Research Centre, Hebei Provincial Hospital of Chinese Medicine, Shijiazhuang 050000, PR China. ; Qiao Wang:1.School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, PR China. Electronic address: 17200934@hebmu.edu.cn. ;
期刊：Toxic effects of Tripterygium glycoside tablets on the reproductive system of male rats by metabolomics, cytotoxicity, and molecular docking
DOI：10.1016/j.phymed.2023.154813
影响因子 ：7.9
引用产品： TM3细胞专用培养基 , TM4细胞专用培养基 , TM3 细胞 , TM4 细胞
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1-Nitropyrene disrupts testicular steroidogenesis via oxidative stress-evoked PERK-eIF2α pathway (2023-05-17)
作者：Xiu-Liang Li:1.Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes & Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, 230032, China. ; Yu-Lin Liu:1.Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes & Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, 230032, China. ; Jia-Yu Liu:1.Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes & Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, 230032, China. ; Yan-Yan Zhu:1.Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes & Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, 230032, China. ; Xin-Xin Zhu:1.Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes & Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, 230032, China. ; Wei-Wei Zha
期刊：1-Nitropyrene disrupts testicular steroidogenesis via oxidative stress-evoked PERK-eIF2α pathway
DOI：10.1016/j.ecoenv.2023.115027
影响因子 ：6.8
引用产品： TM3 细胞 , TM3细胞专用培养基
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The rare-earth yttrium induces cell apoptosis and autophagy in the male reproductive system through ROS-Ca2+-CamkII/Ampk axis (2023-07-20)
作者：Fangpeng Hou:1.Center for Immunology, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, Jiangxi 341000, China; The First School of Clinical Medicine, Gannan Medical University, Ganzhou, Jiangxi 341000, China. ; Junyun Huang:1.Department of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi 341000, China. ; Furong Qing:1.Center for Immunology, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, Jiangxi 341000, China; School of Basic Medicine, Gannan Medical University, Ganzhou, Jiangxi 341000, China. ; Tianfu Guo:1.School of Basic Medicine, Gannan Medical University, Ganzhou, Jiangxi 341000, China. ; Sijia Ouyang:1.School of Basic Medicine, Gannan Medical University, Ganzhou, Jiangxi 341000, China. ; Lu Xie:1.School of Basic Medicine, Gannan Med
期刊：The rare-earth yttrium induces cell apoptosis and autophagy in the male reproductive system through ROS-Ca2+-CamkII/Ampk axis
DOI：10.1016/j.ecoenv.2023.115262
影响因子 ：6.8
引用产品： TM4 细胞 , TM3 细胞 , GC-1 spg 细胞 , GC-2spd (ts) 细胞 , DMEM/F12 培养基 , DMEM高糖 培养基
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Triphenyl phosphate induced apoptosis of mice testicular Leydig cells and TM3 cells through ROS-mediated mitochondrial fusion inhibition (2023-04-05)
作者：Minxin Wang:1.Department of Histology and Embryology, College of Basic Medicine, Binzhou Medical University, Yantai 264003, China; Xu Rongxiang Regenerative Medicine Research Center, Binzhou Medical University, Yantai 264003, China. ; Jinyu Xu:1.Department of Histology and Embryology, College of Basic Medicine, Binzhou Medical University, Yantai 264003, China; Xu Rongxiang Regenerative Medicine Research Center, Binzhou Medical University, Yantai 264003, China. ; Zhengbo Zhao:1.Department of Histology and Embryology, College of Basic Medicine, Binzhou Medical University, Yantai 264003, China. ; Lichao Gong:1.Department of Histology and Embryology, College of Basic Medicine, Binzhou Medical University, Yantai 264003, China. ; Yu Su:1.Department of Histology and Embryology, College of Basic Medicine, Binzhou Medical University, Yantai 264003, China. ; Zhichao Fang:1.Department of Histology and Embryology, College of Basic Medicine, Binzhou Medical University, Yantai 264003, China. ;
期刊：Triphenyl phosphate induced apoptosis of mice testicular Leydig cells and TM3 cells through ROS-mediated mitochondrial fusion inhibition
DOI：10.1016/j.ecoenv.2023.114876
影响因子 ：6.8
引用产品： TM3 细胞
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Phytochemical analysis and in vitro and in vivo antioxidant properties of Plagiorhegma dubia Maxim as a medicinal crop for diabetes treatment (2023-03-09)
作者：Hui Sun: 1.Tonghua Normal University, School of Pharmacy and Medicine, Green Medicinal Chemistry Laboratory, Tonghua 134002, China; Meihua Chen: 1.Tonghua Normal University, School of Pharmacy and Medicine, Green Medicinal Chemistry Laboratory, Tonghua 134002, China;2.Yanbian University, College of Medicine, Yanji 133000, China; Xu He: 1.Tonghua Normal University, School of Pharmacy and Medicine, Green Medicinal Chemistry Laboratory, Tonghua 134002, China;2.Yanbian University, College of Medicine, Yanji 133000, China; Yue Sun: 1.Tonghua Normal University, School of Pharmacy and Medicine, Green Medicinal Chemistry Laboratory, Tonghua 134002, China;2.Yanbian University, College of Medicine, Yanji 133000, China; Jiaxin Feng: 1.Tonghua Normal University, School of Pharmacy and Medicine, Green Medicinal Chemistry Laboratory, Tonghua 134002, China;2.Yanbian University, College of Medicine, Yanji 133000, China; Xin Guo: 1.Tonghua Normal University, School of Pharmacy and Medicine, Green Medic
期刊：Phytochemical analysis and in vitro and in vivo antioxidant properties of Plagiorhegma dubia Maxim as a medicinal crop for diabetes treatment
DOI：10.1016/j.arabjc.2023.104788
影响因子 ：6.0
引用产品： TM3 细胞
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Prenatal DEHP Exposure Induces Premature Testicular Aging by Promoting Leydig Cell Senescence through the MAPK Signaling Pathways (2023-05-28)
作者：Xie Qigen:1.Department of Pediatric Surgery, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. ; 2.Department of Andrology, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. ; Cao Haiming:1.Department of Andrology, Reproductive Center of the Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518000, China. ; Xia Kai:1.Department of Andrology, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. ; Gao Yong:1.Department of Andrology, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. ; Deng Chunhua:1.Department of Andrology, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China. ;
期刊：Prenatal DEHP Exposure Induces Premature Testicular Aging by Promoting Leydig Cell Senescence through the MAPK Signaling Pathways
影响因子 ：3.7
引用产品： TM3 细胞
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Rosmarinic acid ameliorates autoimmune responses through suppression of intracellular nucleic acid-mediated type I interferon expression (2023-05-26)
作者：Xiao-Wei Li:1.Nanhu Laboratory, National Center of Biomedical Analysis, 27 Tai-Ping Road, Beijing, 100850, China. ; Sen-Chao Yuan:1.Nanhu Laboratory, National Center of Biomedical Analysis, 27 Tai-Ping Road, Beijing, 100850, China. ; Miao Wang:1.Nanhu Laboratory, National Center of Biomedical Analysis, 27 Tai-Ping Road, Beijing, 100850, China. ; Zhi-Hui Su:1.Nanhu Laboratory, National Center of Biomedical Analysis, 27 Tai-Ping Road, Beijing, 100850, China. ; Ming Zhao:1.Nanhu Laboratory, National Center of Biomedical Analysis, 27 Tai-Ping Road, Beijing, 100850, China. ; Tao Li:1.Nanhu Laboratory, National Center of Biomedical Analysis, 27 Tai-Ping Road, Beijing, 100850, China. ; Xue-Min Zhang:1.Nanhu Laboratory, National Center of Biomedical Analysis, 27 Tai-Ping Road, Beijing, 100850, China. ; Wen Xue:1.Nanhu Laboratory, National Center of Biomedical Analysis, 27 Tai-Ping Road, Beijing, 100850, China. Electronic address: wxue@xmail.ncba.ac.cn. ; Wei-Hua Li:1.Nanhu Laboratory,
期刊：Rosmarinic acid ameliorates autoimmune responses through suppression of intracellular nucleic acid-mediated type I interferon expression
DOI：10.1016/j.bbrc.2023.05.113
影响因子 ：3.1
引用产品： TM3 细胞
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Knockdown of ZnT4 Induced Apoptosis, Inhibited Proliferation and testosterone synthesis of TM3 cells (2023-09-21)
作者：Huanhuan Li:1.Hebei Key Laboratory of Reproductive Medicine, Hebei Reproductive Health Hospital, No. 480 Heping Street, Shijiazhuang, 050071, Xinhua District, Hebei, China. ; Yuejia Li:1.Graduate School of Hebei Medical University, Shijiazhuang, 050017, China. ; Junsheng Liu:1.Graduate School of Hebei Medical University, Shijiazhuang, 050017, China. ; Xuan Liu:1.Graduate School of Hebei Medical University, Shijiazhuang, 050017, China. ; Yuanjing Li:1.School of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang, 050024, China. ; Shusong Wang:1.Hebei Key Laboratory of Reproductive Medicine, Hebei Reproductive Health Hospital, No. 480 Heping Street, Shijiazhuang, 050071, Xinhua District, Hebei, China. wshsong@126.com. ; 2.Graduate School of Hebei Medical University, Shijiazhuang, 050017, China. wshsong@126.com. ; 3.School of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang, 050024, China. wshsong@126.com. ; Jing Ma:1.Hebei Key Laboratory of
期刊：Knockdown of ZnT4 Induced Apoptosis, Inhibited Proliferation and testosterone synthesis of TM3 cells
DOI：10.1007/s11626-023-00804-z
影响因子 ：2.1
引用产品： TM3 细胞 , TM3细胞专用培养基
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MicroRNA profiling reveals the role of miR-133b-3p in promoting apoptosis and inhibiting cell proliferation and testosterone synthesis in mouse TM3 cells (2023-01-30)
作者：Chengshuang Pan:1.Department of Reproductive Medical Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China. ; Qianjin Fei:1.Department of Reproductive Medical Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China. ; Jianyuan Jin:1.Department of Reproductive Medical Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China. ; Jiujia Zheng:1.Department of Reproductive Medical Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China. ; Didi Wu:1.Duolaimi Biotechnology (Wuhan) Co., Ltd, Wuhan, 430000, China. ; Honggang Li:1.Institute of Reproductive Health/Center of Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, Hubei, China. ; Xuefeng Huang:1.Department of Reproductive Medical Center, The First Affiliated Hospital of Wenzhou Medical Univers
期刊：MicroRNA profiling reveals the role of miR-133b-3p in promoting apoptosis and inhibiting cell proliferation and testosterone synthesis in mouse TM3 cells
DOI：10.1007/s11626-022-00745-z
影响因子 ：2.1
引用产品： TM3 细胞
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Melatonin inhibits autophagy in TM3 cells via AKT/FOXO1 pathway (2001-02-20)
作者：Zhiqiang Li:1.Joint Laboratory of the Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, 130118, Changchun, Jilin, China. ; 2.Key Lab of the Animal Production, Product Quality, and Security, Ministry of Education, Jilin Agricultural University, 130118, Changchun, Jilin, China. ; Hongtao Wang:1.Joint Laboratory of the Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, 130118, Changchun, Jilin, China. ; 2.Key Lab of the Animal Production, Product Quality, and Security, Ministry of Education, Jilin Agricultural University, 130118, Changchun, Jilin, China. ; Kaiyan Zhang:1.Joint Laboratory of the Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, 130118, Changchun, Jilin, China. ; 2.Key Lab of the Animal Production, Product Quality, and Security, Ministry of Education, Jilin Agricultural University, 130118,
期刊：Melatonin inhibits autophagy in TM3 cells via AKT/FOXO1 pathway
DOI：10.1007/s11033-021-07107-0
影响因子 ：2.8
引用产品： TM3 细胞
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Prenatal exposure to environmentally relevant levels of PBDE-99 leads to testicular dysgenesis with steroidogenesis disorders (2010-01-20)
作者：Tianxin Zhao:1.Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China. ; Xiangliang Tang:1.Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China. ; Dian Li:1.Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, Chi
期刊：Prenatal exposure to environmentally relevant levels of PBDE-99 leads to testicular dysgenesis with steroidogenesis disorders
DOI：10.1016/j.jhazmat.2021.127547
影响因子 ：14.2
引用产品： TM3 细胞 , TM3细胞专用培养基
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1,25-Dihydroxyvitamin D deficiency accelerates male reproductive senescence in aging mice and 1,25(OH)2D3 alleviates oxidative stress via NF-κB/SOD (2004-01-20)
作者：Jialing He:1.Department of Anatomy, Histology and Embryology, School of Basic Medical Science, Nanjing Medical University, Nanjing, China. ; Hui Wang:1.Department of Anatomy, Histology and Embryology, School of Basic Medical Science, Nanjing Medical University, Nanjing, China. ; Jiaxin Shi:1.Department of Anatomy, Histology and Embryology, School of Basic Medical Science, Nanjing Medical University, Nanjing, China. ; Mengfan Shi:1.Department of Anatomy, Histology and Embryology, School of Basic Medical Science, Nanjing Medical University, Nanjing, China. ; Weiwei Sun:1.Department of Anatomy, Histology and Embryology, School of Basic Medical Science, Nanjing Medical University, Nanjing, China. ;
期刊：1,25-Dihydroxyvitamin D deficiency accelerates male reproductive senescence in aging mice and 1,25(OH)2D3 alleviates oxidative stress via NF-κB/SOD
DOI：10.1152/ajpendo.00531.2020
影响因子 ：5.1
引用产品： TM3 细胞
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A Protein from Dioscorea polystachya (Chinese Yam) Improves Hydrocortisone-Induced Testicular Dysfunction by Alleviating Leydig Cell Injury via Upregulation of the Nrf2 Pathway (2011-01-20)
作者：Shiting Yu:1.Jilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China. ; Bing Han:1.Jilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China. ; Xin Xing:1.Jilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China. ; Yixuan Li:1.Jilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China. ; Daqing Zhao:1.Jilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China. ; Meichen Liu:1.Jilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China. ; Siming Wang:1.Jilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province, China. ;
期刊：A Protein from Dioscorea polystachya (Chinese Yam) Improves Hydrocortisone-Induced Testicular Dysfunction by Alleviating Leydig Cell Injury via Upregulation of the Nrf2 Pathway
影响因子 ：0.0
引用产品： TM3 细胞 , TM3细胞专用培养基
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Oxidized-LDL inhibits testosterone biosynthesis by affecting mitochondrial function and the p38 MAPK/COX-2 signaling pathway in Leydig cells (2008-00-20)
作者：Jun Jing:1.Jinling Hospital Department Reproductive Medical Center, Clinical School of Medical College, Nanjing University, Nanjing, Jiangsu, China. ; 2.State Key Laboratory of Reproductive Medicine, Nanjing Medicine University, Nanjing, Jiangsu, China. ; Ning Ding:1.The School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong, China. ; Dandan Wang:1.Jinling Hospital Department Reproductive Medical Center, Clinical School of Medical College, Nanjing University, Nanjing, Jiangsu, China. ; 2.State Key Laboratory of Reproductive Medicine, Nanjing Medicine University, Nanjing, Jiangsu, China. ; Xie Ge:1.Jinling Hospital Department Reproductive Medical Center, Clinical School of Medical College, Nanjing University, Nanjing, Jiangsu, China. ; 2.State Key Laboratory of Reproductive Medicine, Nanjing Medicine University, Nanjing, Jiangsu, China. ; Jinzhao Ma:1.Jinling Hospital Department Reproductive Medical Center, Clinical School of Medic
期刊：Oxidized-LDL inhibits testosterone biosynthesis by affecting mitochondrial function and the p38 MAPK/COX-2 signaling pathway in Leydig cells
DOI：10.1038/s41419-020-02751-z
影响因子 ：9.0
引用产品： TM3 细胞
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Melatonin inhibits apoptosis in mouse Leydig cells via the retinoic acid-related orphan nuclear receptor α/p53 pathway (2002-00-20)
作者：Zhiqiang Li:1.Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. ; Jing Zhao:1.Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. ; Hongyu Liu:1.Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. ; Jun Wang:1.Joint Laboratory of Modern Agric
期刊：Melatonin inhibits apoptosis in mouse Leydig cells via the retinoic acid-related orphan nuclear receptor α/p53 pathway
影响因子 ：6.1
引用产品： TM3 细胞
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BMAL1 knockdown promoted apoptosis and reduced testosterone secretion in TM3 Leydig cell line (2004-00-20)
作者：He Ding:1.Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. ; Jing Zhao:1.Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. ; Hongyu Liu:1.Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. ; Jun Wang:1.Joint Laboratory of Modern Agricultu
期刊：BMAL1 knockdown promoted apoptosis and reduced testosterone secretion in TM3 Leydig cell line
DOI：10.1016/j.gene.2020.144672
影响因子 ：3.5
引用产品： TM3 细胞
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Melatonin Inhibits Apoptosis and Oxidative Stress of Mouse Leydig Cells via a SIRT1-Dependent Mechanism (2008-09-20)
作者：Gaoqing Xu:1.College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China. ; Jing Zhao:1.College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China. ; Hongyu Liu:1.College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China. ; Jun Wang:1.College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China. junwang2004@126.com. ; Wenfa Lu:1.College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China. wenfa2004@163.com. ;
期刊：Melatonin Inhibits Apoptosis and Oxidative Stress of Mouse Leydig Cells via a SIRT1-Dependent Mechanism
影响因子 ：4.6
引用产品： TM3 细胞
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