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产品概述
| 名称 | SW1116 (人结肠腺癌细胞) (STR鉴定正确) |
| 别称 | SW-1116; SW 1116 |
| 种属 | 人类 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，100%, 温度：37℃
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| 培养方案B（可选） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:3 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 1.该细胞推荐使用Leibovitz's L-15培养基进行培养，Leibovitz's L-15不可以通入二氧化碳，会产生细胞毒性；2.如您没有无二氧化碳的培养箱，可使用DMEM替代Leibovitz's L-15，使用DMEM培养基时即可正常通入5%二氧化碳；3.配套专用培养基默认Leibovitz's L-15配置，如需DMEM配方，请联系销售下单备注更改。 |
| 背景描述 | SW1116细胞CSAp阴性(CSAp-)、结肠抗原3阴性；SW1116细胞角蛋白免疫过氧化物酶染色阳性。癌基因检测表明，SW1116细胞c-myc、K-ras、H-ras、myb、sis和fos的表达呈阳性，未检测到癌基因N-myc和N-ras的表达。SW1116还表达肿瘤特异的核基质蛋白CC-4、CC-5和CC-6。 |
| 年龄（性别） | 男性，73岁 |
| 组织来源 | 结肠腺癌Ⅲ期 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肠癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~96-144 hours |
| 致瘤性 | Yes, in nude mice. |
| 抗原表达情况 | Blood Type O, Rh+ |
| 基因表达情况 | carcinoembryonic antigen (CEA) 2654 ng/10^6 cells/10 days; keratin |
| 保藏机构 | ATCC; CCL-233 ECACC; 87071006 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,11 D2S1338 24,25 D3S1358 16 D5S818 11,12 D7S820 12 D8S1179 10,11 D13S317 11,14 D16S539 9,12 D18S51 13 D19S433 14 D21S11 28,29 FGA 21,22 PentaD 11,13 PentaE 10,12 TH01 6 TPOX 8,11 vWA 14,19 D6S1043 12 D12S391 17 D2S441 14 -
STR鉴定图
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参考文献
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The Active Fraction of Polyrhachis vicina Roger (AFPR) activates ERK to cause necroptosis in colorectal cancer (2023-04-12)
作者：Dong-Mei Li:1.School of Chemistry & Pharmaceutical Sciences, State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin, 541004, China; Department of Pharmacology, Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Chinese Medicine and Pharmaceutical Science, Nanning, 530022, China. ; Fu-Cui Zhu:1.Pharmaceutical College, Guangxi Medical University, Nanning, 530021, China. ; Jie Wei:1.Department of Pharmacology, Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Chinese Medicine and Pharmaceutical Science, Nanning, 530022, China. ; Jia-Xiu Xie:1.Department of Pharmacology, Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Chinese Medicine and Pharmaceutical Science, Nanning, 530022, China. ; Jun-Hui He:1.Department of Pharmacology, Guangxi Key Laboratory of Traditional Chinese Medicine Qua
期刊：The Active Fraction of Polyrhachis vicina Roger (AFPR) activates ERK to cause necroptosis in colorectal cancer
影响因子 ：5.4
引用产品： SW1116 细胞 , HCT-8 [HRT-18] 细胞
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IRF1 suppresses colon cancer proliferation by reducing SPI1-mediated transcriptional activation of GPX4 and promoting ferroptosis (2023-07-29)
作者：Yilin Chen:1.Department of General Surgery, The Second Affiliated Hospital of Fujian Medical University, Fujian, China. ; Beian Lin:1.Department of General Surgery, The Second Affiliated Hospital of Fujian Medical University, Fujian, China. ; Shiyu Yang:1.Department of General Surgery, The Second Affiliated Hospital of Fujian Medical University, Fujian, China. ; Jingshan Huang:1.Department of General Surgery, The Second Affiliated Hospital of Fujian Medical University, Fujian, China. Electronic address: hjs_0829@126.com. ;
期刊：IRF1 suppresses colon cancer proliferation by reducing SPI1-mediated transcriptional activation of GPX4 and promoting ferroptosis
DOI：10.1016/j.yexcr.2023.113733
影响因子 ：3.7
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Methyltransferase like 3 enhances pinin mRNA stability through N6-methyladenosine modification to augment tumourigenesis of colon adenocarcinoma (2022-08-22)
作者：Min He:1.Department of Gastroenterology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, P.R. China. ; Danling Jiang:1.Department of Gastroenterology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, P.R. China. ; Anying Xun:1.Department of Gastroenterology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, P.R. China. ; Jian Yang:1.Department of Gastroenterology, Shenzhen Qianhai Shekou Free Trade Zone Hospital, Shenzhen, Guangdong, 518067, P.R. China. ; Qianjiang Luo:1.Department of Gastroenterology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, P.R. China. ; Huihua Wu:1.Department of Gastroenterology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, P.R. China. ;
期刊：Methyltransferase like 3 enhances pinin mRNA stability through N6-methyladenosine modification to augment tumourigenesis of colon adenocarcinoma
DOI：10.1113/EP090273
影响因子 ：2.9
引用产品： RKO 细胞 , LS 174T [LS174T] 细胞 , CW-2 细胞 , SW1116 细胞 , 人结肠黏膜上皮细胞 , 人结肠黏膜上皮细胞完全培养基
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Ginsenoside Rh3 Inhibits Proliferation and Induces Apoptosis of Colorectal Cancer Cells (2010-09-20)
作者：Zhongyi Cong:1.Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun, China. ; Qing Zhao:1.Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun, China. ; Bo Yang:1.Department of Ophthalmology, the Second Hospital of Jilin University, Jilin University, Changchun, China. ; Dengli Cong:1.Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun, China. ; Yulai Zhou:1.Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun, China. ; Xi Lei:1.Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun, China. ; Xinmin Zhang:1.Department of Regenerative Medicine, School of Pharmaceutical Science, Jilin University, Changchun, China, zhangxinmin@jlu.edu.cn. ;
期刊：Ginsenoside Rh3 Inhibits Proliferation and Induces Apoptosis of Colorectal Cancer Cells
影响因子 ：3.1
引用产品： SW1116 细胞
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Long non-coding RNA H19 confers 5-Fu resistance in colorectal cancer by promoting SIRT1-mediated autophagy (2011-08-20)
作者：Meng Wang:1.Department of Colorectal Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China. ; Dong Han:1.Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, 150081, China. ; Ziming Yuan:1.Department of Colorectal Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China. ; Hanqing Hu:1.Department of Colorectal Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China. ; Zhixun Zhao:1.Department of Colorectal Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China. ; Runkun Yang:1.Department of Colorectal Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China. ; Yinghu Jin:1.Department of Colorectal Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China. ; Chaoxia Zou:1.Department of Biochemistry and Molecular Biology, Harbin Medical U
期刊：Long non-coding RNA H19 confers 5-Fu resistance in colorectal cancer by promoting SIRT1-mediated autophagy
影响因子 ：9.0
引用产品： SW1116 细胞
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