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产品概述
名称 | HCCC-9810 (人胆管细胞型肝癌细胞) (STR鉴定正确) |
别称 | HCCC9810; Hccc9810 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
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推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | HCCC-9810细胞源自一位女性肝胆管细胞癌患者,呈上皮细胞样。HCCC-9810细胞染色体模式数为71,但其染色体数目可以在22-117的范围内变动。HCCC-9810细胞倍增时间为20.4小时;细胞内AFP、CEA和CA19-9的分泌水平低,HCCC-9810细胞在裸鼠中的成瘤率为20%。 |
年龄(性别) | 女性 |
组织来源 | 肝胆管细胞癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肝胆癌细胞 |
致瘤性 | Yes, in nude mice. |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,12 D2S1338 17,19 D3S1358 17 D5S818 11 D7S820 10,12 D8S1179 10,13 D13S317 11 D16S539 9,12 D18S51 15 D19S433 13,14 D21S11 30,32 FGA 23,24 PentaD 9,13 PentaE 19 TH01 9 TPOX 8,11 vWA 16,17 D6S1043 19 D12S391 19 D2S441 12 -
STR鉴定图
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参考文献
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SQSTM1/p62 confers resistance of intrahepatic cholangiocarcinoma cells to 5-Fluorouracil by promoting Nrf2 nuclear translocation (2025-01-04)
期刊:Molecular & Cellular Toxicology
DOI:10.1007/s13273-024-00495-x
影响因子 :1.1
引用产品: HCCC-9810 细胞 , 青霉素-链霉素溶液(双抗),100×
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AMDHD1 acts as a tumor suppressor and contributes to activation of TGF-β signaling pathway in cholangiocarcinoma (2024-08-14)
期刊:CELL DEATH AND DIFFERENTIATION
DOI:10.1038/s41418-024-01361-y
影响因子 :13.7
引用产品: RBE 细胞 , HCCC-9810 细胞 , CCLP-1 细胞 , HuCC-T1 细胞 , QBC939 细胞 , SNU-869 细胞
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CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis (2024-12-18)
期刊:CANCER RESEARCH
DOI:10.1158/0008-5472.CAN-24-0147
影响因子 :12.5
引用产品: HuCC-T1 细胞 , RBE 细胞 , HCCC-9810 细胞 , Hep 3B2.1-7 细胞 , HFL1 细胞 , HuH-1 细胞 , HuH-7 细胞
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The heterogeneity of signaling pathways and drug responses in intrahepatic cholangiocarcinoma with distinct genetic mutations (2024-01-11)
期刊:Cell Death & Disease
DOI:10.1038/s41419-023-06406-7
影响因子 :9.0
引用产品: HCCC-9810 细胞
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ETV4 promotes the progression of cholangiocarcinoma by regulating glycolysis via the TGF-β signaling (2024-06-14)
期刊:Translational Oncology
DOI:10.1016/j.tranon.2024.102035
影响因子 :4.5
引用产品: HuCC-T1 细胞 , RBE 细胞 , HCCC-9810 细胞
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Protein regulator of cytokinesis 1 accentuates cholangiocarcinoma progression via mTORC1-mediated glycolysis (2024-02-28)
期刊:Human Cell
DOI:10.1007/s13577-024-01032-7
影响因子 :4.3
引用产品: HCCC-9810 细胞 , HuCC-T1 细胞 , RBE 细胞
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UBA3 promotes the occurrence and metastasis of intrahepatic cholangiocarcinoma through MAPK signaling pathway: UBA3 promotes the occurrence and metastasis of ICC (2024-01-31)
期刊:ACTA BIOCHIMICA ET BIOPHYSICA SINICA
影响因子 :3.3
引用产品: HCCC-9810 细胞 , RBE 细胞 , QBC939 细胞 , HuCC-T1 细胞
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Huaier inhibits cholangiocarcinoma cells through the twist1/FBP1/Wnt/β-catenin axis (2024-07-23)
期刊:MOLECULAR BIOLOGY REPORTS
DOI:10.1007/s11033-024-09738-5
影响因子 :2.6
引用产品: HCCC-9810 细胞 , RBE 细胞
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Repression of LSD1/KDM1A activity improves the response of liver cancer cells to the lenvatinib (2024-03-28)
期刊:Discover Oncology
DOI:10.1007/s12672-024-00947-9
影响因子 :2.2
引用产品: HCCC-9810 细胞
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METTL3-mediated m6A modification promotes chemoresistance of intrahepatic cholangiocarcinoma by up-regulating NRF2 to inhibit ferroptosis in cisplatin-resistant cells (2024-11-01)
期刊:JOURNAL OF CHEMOTHERAPY
DOI:10.1080/1120009X.2024.2421700
影响因子 :1.9
引用产品: HuCC-T1 细胞 , RPMI-1640 培养基 , 特级胎牛血清 , HCCC-9810 细胞 , 青霉素-链霉素溶液(双抗),100×
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Development of potent antibody drug conjugates against ICAM1+ cancer cells in preclinical models of cholangiocarcinoma (2023-09-16)
期刊:npj Precision Oncology
DOI:10.1038/s41698-023-00447-z
影响因子 :7.9
引用产品: HuCC-T1 细胞 , HCCC-9810 细胞
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Circ_0020256 induces fibroblast activation to drive cholangiocarcinoma development via recruitment of EIF4A3 protein to stabilize KLF4 mRNA (2023-05-13)
期刊:Cell Death Discovery
DOI:10.1038/s41420-023-01439-5
影响因子 :7.0
引用产品: HCCC-9810 细胞 , RBE 细胞
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Oncogenic Role of the NFATC2/NEDD4/FBP1 Axis in Cholangiocarcinoma (2023-06-05)
期刊:LABORATORY INVESTIGATION
DOI:10.1016/j.labinv.2023.100193
影响因子 :5.0
引用产品: RBE 细胞 , HCCC-9810 细胞
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Identification of SPRYD4 as a tumour suppressor predicts prognosis and correlates with immune infiltration in cholangiocarcinoma (2023-05-04)
期刊:BMC CANCER
DOI:10.1186/s12885-023-10810-9
影响因子 :3.8
引用产品: HuCC-T1 细胞 , RBE 细胞 , CCLP-1 细胞 , huh28 细胞 , QBC939 细胞 , HCCC-9810 细胞
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Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42 (2023-03-26)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2023.116492
影响因子 :3.8
引用产品: 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , HCCC-9810 细胞 , 人肝内胆管上皮细胞 , 人肝内胆管上皮细胞完全培养基
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METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10 (2022-12-07)
期刊:Cancer Cell International
DOI:10.1186/s12935-022-02809-2
影响因子 :6.4
引用产品: RBE 细胞 , HCCC-9810 细胞
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7-Methoxy-13-dehydroxypaxilline: New indole diterpenoid from an endophytic fungus Penicillium sp. Nb 19 (2022-08-05)
期刊:NATURAL PRODUCT RESEARCH
DOI:10.1080/14786419.2022.2107639
影响因子 :2.5
引用产品: MCF7 [MCF-7] 细胞 , Hep G2 细胞 , HCCC-9810 细胞
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Circ_0000284 facilitates the growth, metastasis and glycolysis of intrahepatic cholangiocarcinoma through miR-152-3p-mediated PDK1 expression. (2022-11-04)
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.1
引用产品: RBE 细胞 , HCCC-9810 细胞 , 人肝内胆管上皮细胞
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LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis (2021-02-08)
期刊:Bmc Cancer
DOI:10.1186/s12885-021-07838-0
影响因子 :3.8
引用产品: HCCC-9810 细胞 , RBE 细胞
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Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma (2020-11-10)
期刊:Aging-US
影响因子 :5.2
引用产品: HCCC-9810 细胞 , RBE 细胞
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Curcumol Exerts Anticancer Effect in Cholangiocarcinoma Cells via Down-Regulating CDKL3 (2018-03-20)
期刊:Frontiers in Physiology
影响因子 :4.0
引用产品: HCCC-9810 细胞
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Unique Responses of Hepatocellular Carcinoma and Cholangiocarcinoma Cell Lines toward Cantharidin and Norcantharidin (2018-05-25)
期刊:Journal of Cancer
影响因子 :3.9
引用产品: HCCC-9810 细胞 , RBE 细胞
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