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产品概述
名称 | HCCC-9810 (人胆管细胞型肝癌细胞) (STR鉴定正确) |
别称 | HCCC9810; Hccc9810 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | HCCC-9810细胞源自一位女性肝胆管细胞癌患者,呈上皮细胞样。HCCC-9810细胞染色体模式数为71,但其染色体数目可以在22-117的范围内变动。HCCC-9810细胞倍增时间为20.4小时;细胞内AFP、CEA和CA19-9的分泌水平低,HCCC-9810细胞在裸鼠中的成瘤率为20%。 |
年龄(性别) | 女性 |
组织来源 | 肝胆管细胞癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肝胆癌细胞 |
致瘤性 | Yes, in nude mice. |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,12 D2S1338 17,19 D3S1358 17 D5S818 11 D7S820 10,12 D8S1179 10,13 D13S317 11 D16S539 9,12 D18S51 15 D19S433 13,14 D21S11 30,32 FGA 23,24 PentaD 9,13 PentaE 19 TH01 9 TPOX 8,11 vWA 16,17 D6S1043 19 D12S391 19 D2S441 12 -
STR鉴定图
参考文献
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The heterogeneity of signaling pathways and drug responses in intrahepatic cholangiocarcinoma with distinct genetic mutations (2024-01-11)
作者:Yangyang Feng:1.Cancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China. ; 2.Zhuhai UM Science & Technology Research Institute, Zhuhai, Guangdong, China. ; 3.Centre for Precision Medicine Research and Training, Faculty of Health Sciences, University of Macau, Macau SAR, China. ; Ming Zhao:1.Cancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China. ; 2.Centre for Precision Medicine Research and Training, Faculty of Health Sciences, University of Macau, Macau SAR, China. ; 3.Department of Gastroenterology, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, China. ; Lijian Wang:1.Cancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China. ; 2.Centre for Precision Medicine Research and Training, Faculty of Health Sciences, University of Macau, Macau SAR, China. ; Ling Li:1.Cancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China. ; 2.Centre for Prec
期刊:The heterogeneity of signaling pathways and drug responses in intrahepatic cholangiocarcinoma with distinct genetic mutations
DOI:10.1038/s41419-023-06406-7
影响因子 :9.0
引用产品: HCCC-9810 细胞
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Protein regulator of cytokinesis 1 accentuates cholangiocarcinoma progression via mTORC1-mediated glycolysis (2024-02-28)
作者:Chao Zhang:1.Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Shandong University, 324 Jingwuwei 7Th Road, Jinan, 250021, Shandong, People's Republic of China. ; 2.Department of Hepatobiliary Surgery, Linyi People's Hospital, Linyi, 276034, Shandong, People's Republic of China. ; Chengkun Qin:1.Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Shandong University, 324 Jingwuwei 7Th Road, Jinan, 250021, Shandong, People's Republic of China. qinchengkun_slyy@163.com. ;
期刊:Protein regulator of cytokinesis 1 accentuates cholangiocarcinoma progression via mTORC1-mediated glycolysis
DOI:10.1007/s13577-024-01032-7
影响因子 :4.3
引用产品: HCCC-9810 细胞 , HuCC-T1 细胞 , RBE 细胞
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Repression of LSD1/KDM1A activity improves the response of liver cancer cells to the lenvatinib (2024-03-28)
作者:Yi Zong:1.Department of Radiology, The Fourth Affiliated Hospital Zhejiang University School of Medicine, Yiwu, Zhejiang, China. ; Zhigang Tao:1.Department of Radiology, Hangzhou Cancer Hospital, Hangzhou, Zhejiang, China. ; Siyi Jiang:1.Intensive Care Unit, The Fourth Affiliated Hospital Zhejiang University School of Medicine, Yiwu, Zhejiang, China. ; Minyuan Wang:1.Department of Radiology, The Fourth Affiliated Hospital Zhejiang University School of Medicine, Yiwu, Zhejiang, China. ; Weihua Yu:1.Department of Gastroenterology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, China. yuweihua84@zju.edu.cn. ;
期刊:Repression of LSD1/KDM1A activity improves the response of liver cancer cells to the lenvatinib
DOI:10.1007/s12672-024-00947-9
影响因子 :2.2
引用产品: HCCC-9810 细胞
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Development of potent antibody drug conjugates against ICAM1+ cancer cells in preclinical models of cholangiocarcinoma (2023-09-16)
作者:Bing Zhu:1.Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, 310022, China. ; 2.Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310018, China. ; Xinyan Wang:1.Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, 310022, China. ; 2.Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310018, China. ; 3.Institute of Molecular Medicine, Hangzhou Institute for Advanced Study (UCAS), Hangzhou, Zhejiang, 310000, China. ; Takaya Shimura:1.Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan. ; Andrew C Huang:1.MabPlex International, Yantai, Shandong, 264006, China. ; Nana Kong:1.MabPlex International, Yantai, Shandong, 264006, China. ; Yujie Dai:1.MabPlex International, Yantai, Shandong, 264006, China
期刊:Development of potent antibody drug conjugates against ICAM1+ cancer cells in preclinical models of cholangiocarcinoma
DOI:10.1038/s41698-023-00447-z
影响因子 :7.9
引用产品: HuCC-T1 细胞 , HCCC-9810 细胞
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Circ_0020256 induces fibroblast activation to drive cholangiocarcinoma development via recruitment of EIF4A3 protein to stabilize KLF4 mRNA (2023-05-13)
作者:Zongyan Li:1.Department of Pancreatic Hepatobiliary Surgery, Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510650, Guangdong Province, P.R. China. ; Zuxiao Chen:1.Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, Guangdong Province, P.R. China. ; Shiying Li:1.Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, Guangdong Province, P.R. China. ; Xiangjun Qian:1.Department of Pancreatic Hepatobiliary Surgery, Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510650, Guangdong Province, P.R. China. ; Lei Zhang:1.Department of Pancreatic Hepatobiliary Surgery, Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510650, Guangdong Province, P.R. China. ; Guojie Long:1.Department of Pancre
期刊:Circ_0020256 induces fibroblast activation to drive cholangiocarcinoma development via recruitment of EIF4A3 protein to stabilize KLF4 mRNA
DOI:10.1038/s41420-023-01439-5
影响因子 :7.0
引用产品: HCCC-9810 细胞 , RBE 细胞
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Oncogenic Role of the NFATC2/NEDD4/FBP1 Axis in Cholangiocarcinoma (2023-06-05)
作者:Wei Zhao:1.Department of Hepatobiliary and Pancreatic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address: zhaoweiqdfy@126.com. ; Jing Zhao:1.Department of Pathology, the Affiliated Hospital of Qingdao University, Qingdao, China. ; Kun Li:1.Department of Hepatobiliary and Pancreatic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, China. ; Yanjiao Hu:1.Department of Pathology, the Affiliated Hospital of Qingdao University, Qingdao, China. ; Dongxia Yang:1.Department of Hepatobiliary and Pancreatic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, China. ; Bin Tan:1.Department of Hepatobiliary and Pancreatic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, China. ; Jian Shi:1.Department of Hepatobiliary and Pancreatic Surgery, the Affiliated Hospital of Qingdao University, Qingdao, China. ;
期刊:Oncogenic Role of the NFATC2/NEDD4/FBP1 Axis in Cholangiocarcinoma
DOI:10.1016/j.labinv.2023.100193
影响因子 :5.0
引用产品: RBE 细胞 , HCCC-9810 细胞
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Identification of SPRYD4 as a tumour suppressor predicts prognosis and correlates with immune infiltration in cholangiocarcinoma (2023-05-04)
作者:Zuyi Ma:1.Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing, 100005, China. ; Tiange Xie:1.Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing, 100005, China. ; Jia Sun:1.Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing, 100005, China. ; Jianchun Yu:1.Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science a
期刊:Identification of SPRYD4 as a tumour suppressor predicts prognosis and correlates with immune infiltration in cholangiocarcinoma
DOI:10.1186/s12885-023-10810-9
影响因子 :3.8
引用产品: HuCC-T1 细胞 , RBE 细胞 , CCLP-1 细胞 , huh28 细胞 , QBC939 细胞 , HCCC-9810 细胞
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Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42 (2023-03-26)
作者:Xifang Wang:1.Department of Medical Oncology, Shaanxi Provincial People's Hospital, Xi'an 710068, China. ; Xiaomin Zhang:1.Department of Orthopaedics, Xi'an International Medical Center Hospital, Xi'an 710100, China. ; Jingying Sun:1.Shaanxi Provincial Key Laboratory of Infectious and Immunological Diseases, Shaanxi Provincial People's Hospital, Xi'an 710068, China. ; Yang Sun:1.Data Center, Shaanxi Provincial People's Hospital, s 710068, China. ; Yuan Zhang:1.Department of Medical Oncology, Shaanxi Provincial People's Hospital, Xi'an 710068, China. ; Li He:1.Department of Medical Oncology, Shaanxi Provincial People's Hospital, Xi'an 710068, China. ; Ping Wang:1.Department of Pathology, Shaanxi Provincial People's Hospital, Xi'an 710068, China. ; Feng Li:1.Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. Electronic address: li_feng7855@163.com. ; Chao Sun:1.Department of Medical Oncology, Shaanxi
期刊:Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42
DOI:10.1016/j.taap.2023.116492
影响因子 :3.8
引用产品: 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100× , HCCC-9810 细胞 , 人肝内胆管上皮细胞 , 人肝内胆管上皮细胞完全培养基
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METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10 (2022-12-07)
作者:Jingli Cai:1.Center of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease, Tongji University School of Medicine, No. 150, Jimo Road, Pudong New Area, Shanghai, China. 417327108@qq.com. ; Zheng Cui:1.Department of Ultrasonic Medicine, Shanghai East Hospital, Institute of Gallstone Disease, Tongji University School of Medicine, Shanghai, China. ; Jingyi Zhou:1.Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; Bosen Zhang:1.Center of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease, Tongji University School of Medicine, No. 150, Jimo Road, Pudong New Area, Shanghai, China. ; Ruiqi Lu:1.Center of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease, Tongji University School of Medicine, No. 150, Jimo Road, Pudong New Area, Shanghai, China. ; Youcheng Ding:1.Center of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease,
期刊:METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10
DOI:10.1186/s12935-022-02809-2
影响因子 :6.4
引用产品: RBE 细胞 , HCCC-9810 细胞
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7-Methoxy-13-dehydroxypaxilline: New indole diterpenoid from an endophytic fungus Penicillium sp. Nb 19 (2022-08-05)
作者:Jing Yu:1.Yunnan Key Laboratory of Southern Medicine Utilization, Yunnan Branch Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Jinghong, China. ; Jia-Peng Wang:1.Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical, College of Pharmacy, Dali University, Yunnan Dali, China. ; Shi-Fang Liu:1.Yunnan Key Laboratory of Southern Medicine Utilization, Yunnan Branch Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Jinghong, China. ; Cui-Yun Yin:1.Yunnan Key Laboratory of Southern Medicine Utilization, Yunnan Branch Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Jinghong, China. ; De-Ying Tang:1.Yunnan Key Laboratory of Southern Medicine Utilization, Yunnan Branch Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Jinghong, China. ; Yi-Hang Li:1.Yunnan Key Laboratory of Southern Medicine Utilization, Yunnan Branch Institute of Medicinal Plant Development,
期刊:7-Methoxy-13-dehydroxypaxilline: New indole diterpenoid from an endophytic fungus Penicillium sp. Nb 19
DOI:10.1080/14786419.2022.2107639
影响因子 :2.5
引用产品: MCF7 [MCF-7] 细胞 , Hep G2 细胞 , HCCC-9810 细胞
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Circ_0000284 facilitates the growth, metastasis and glycolysis of intrahepatic cholangiocarcinoma through miR-152-3p-mediated PDK1 expression. (2022-11-04)
作者:Jian Sun:1.Department II of General Surgery, Hanchuan People's Hospital, Hanchuan, Hubei, China. ; Menglong Feng:1.Department II of General Surgery, Hanchuan People's Hospital, Hanchuan, Hubei, China. ; Huilian Zou:1.Department of Gynaecology and Obstetrics, Hanchuan People's Hospital, Hanchuan, Hubei, China. ; Yanping Mao:1.Department II of General Surgery, Hanchuan People's Hospital, Hanchuan, Hubei, China. ; Wei Yu:1.Department II of General Surgery, Hanchuan People's Hospital, Hanchuan, Hubei, China. yuwei19811110@163.com. ;
期刊:Circ_0000284 facilitates the growth, metastasis and glycolysis of intrahepatic cholangiocarcinoma through miR-152-3p-mediated PDK1 expression.
影响因子 :2.1
引用产品: RBE 细胞 , HCCC-9810 细胞 , 人肝内胆管上皮细胞
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LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis (2002-01-20)
作者:Wei Zhao:1.Department of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qingdao University, 1677 Wutaishan Road, Qingdao, 266000, People's Republic of China. zhaoweiqdfy@126.com. ; Jing Zhao:1.Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, 266000, People's Republic of China. ; Xiao Guo:1.Heart Center, Qingdao Fuwai Cardiovascular Hospital, Qingdao, 266034, People's Republic of China. ; Yujie Feng:1.Department of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qingdao University, 1677 Wutaishan Road, Qingdao, 266000, People's Republic of China. ; Bingyuan Zhang:1.Department of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qingdao University, 1677 Wutaishan Road, Qingdao, 266000, People's Republic of China. ; Lantian Tian:1.Department of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qingdao University, 1677 Wutaishan Road, Qingdao, 266000, People's Republic of China. ;
期刊:LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis
DOI:10.1186/s12885-021-07838-0
影响因子 :3.8
引用产品: HCCC-9810 细胞 , RBE 细胞
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Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma (2011-00-20)
作者:Xiangyu Zhai:1.Department of Surgery, School of Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China. ; 2.Department of General Surgery, Qilu Hospital of Shandong University, Jinan, China. ; Wei Wang:1.Department of Surgery, School of Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China. ; Yunlong Ma:1.Department of Surgery, School of Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China. ; Yijia Zeng:1.Radiology Department, Qilu Hospital of Shandong University, Jinan, China. ; Dandan Dou:1.School of Basic Medical Sciences, Shandong University, Jinan, China. ; Haoning Fan:1.College of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China. ; Jianping Song:1.Department of Surgery, School of Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China. ; Xin Yu:1.School of Basic Medical Sciences, Shandong University, Jinan, China. ; Danqing Xin:1.School of Basic Medical Sciences, Shandong
期刊:Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma
影响因子 :5.2
引用产品: HCCC-9810 细胞 , RBE 细胞
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Curcumol Exerts Anticancer Effect in Cholangiocarcinoma Cells via Down-Regulating CDKL3 (2003-08-20)
作者:Jinduo Zhang:1.The First Clinical Medical College, Lanzhou University, Lanzhou, China. ; 2.Special Minimally Invasive Surgery, The First Hospital of Lanzhou University, Lanzhou, China. ; 3.School of Basic Medical Sciences, Institute of Genetics, Lanzhou University, Lanzhou, China. ; 4.Gansu Province Institute of Hepatopancreatobiliary, Lanzhou, China. ; 5.Gansu Province Key Laboratory Biotherapy and Regenerative Medicine, Lanzhou, China. ; Gang Su:1.The First Clinical Medical College, Lanzhou University, Lanzhou, China. ; 2.School of Basic Medical Sciences, Institute of Genetics, Lanzhou University, Lanzhou, China. ; Zengwei Tang:1.The First Clinical Medical College, Lanzhou University, Lanzhou, China. ; 2.Special Minimally Invasive Surgery, The First Hospital of Lanzhou University, Lanzhou, China. ; 3.Gansu Province Institute of Hepatopancreatobiliary, Lanzhou, China. ; 4.Gansu Province Key Laboratory Biotherapy and Regenerative Medicine, Lanzhou, China. ; Li Wang:1.School of Basic
期刊:Curcumol Exerts Anticancer Effect in Cholangiocarcinoma Cells via Down-Regulating CDKL3
影响因子 :4.0
引用产品: HCCC-9810 细胞
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Unique Responses of Hepatocellular Carcinoma and Cholangiocarcinoma Cell Lines toward Cantharidin and Norcantharidin (2005-08-20)
作者:Qixiang Ma:1.School of Life Sciences, Centre For Translational Oncology, Beijing University of Chinese Medicine, 11 Beisanhuandong Road, Chaoyang District, Beijing 100029, People's Republic of China. ; Yanyan Feng:1.School of Life Sciences, Centre For Translational Oncology, Beijing University of Chinese Medicine, 11 Beisanhuandong Road, Chaoyang District, Beijing 100029, People's Republic of China. ; Kaiwen Deng:1.School of Life Sciences, Centre For Translational Oncology, Beijing University of Chinese Medicine, 11 Beisanhuandong Road, Chaoyang District, Beijing 100029, People's Republic of China. ; Haozhen Shao:1.School of Life Sciences, Centre For Translational Oncology, Beijing University of Chinese Medicine, 11 Beisanhuandong Road, Chaoyang District, Beijing 100029, People's Republic of China. ; Tongtong Sui:1.School of Life Sciences, Centre For Translational Oncology, Beijing University of Chinese Medicine, 11 Beisanhuandong Road, Chaoyang District, Beijing 100029, People's R
期刊:Unique Responses of Hepatocellular Carcinoma and Cholangiocarcinoma Cell Lines toward Cantharidin and Norcantharidin
影响因子 :3.9
引用产品: HCCC-9810 细胞 , RBE 细胞
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