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产品概述
| 名称 | Hep 3B2.1-7 (人肝癌细胞) (STR鉴定正确) |
| 别称 | Hep 3B2_1-7; Hep 3B2; HEP-3B2; HEP3B2; Hep-3B; HEP-3B; Hep 3B; Hep3B; HEP3B |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:3 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | Hep 3B2.1-7细胞是来自8岁男性黑人的组织。Hep 3B2.1-7细胞的染色体模式数目为60，在裸鼠中能致瘤。Hep 3B2.1-7细胞整合了完整的乙型肝炎病毒基因组，需在2级生物安全防护下操作。 |
| 年龄（性别） | 男性；8岁 |
| 组织来源 | 肝细胞癌，肝 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肝癌细胞 |
| 生物安全等级 | BSL-2 |
| 倍增时间 | ~40-50 hours |
| 致瘤性 | Yes, in nude mice. |
| 基因表达情况 | alpha-fetoprotein (AFP, alpha fetoprotein); hepatitis B surface antigen (HBsAg); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1-antitrypsin); transferrin; ,alpha1 antichymotrypsin (alpha-1-antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen complement (C3, C4), C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein); ,alpha2 HS glycoprotein (alpha-2-HS-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol-binding protein) |
| 保藏机构 | ATCC; HB-8064 BCRC; 60434 BCRJ; 0357 DSMZ; ACC-93 ECACC; 86062703 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 8 D2S1338 21,25 D3S1358 15 D5S818 13 D7S820 8,10 D8S1179 12 D13S317 12,14 D16S539 10 D18S51 20 D19S433 12.2,14 D21S11 30,31 FGA 18 PentaD 12,14 PentaE 5,16 TH01 6,7 TPOX 9 vWA 17 D6S1043 12,17 D12S391 17 D2S441 10,12 -
STR鉴定图
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参考文献
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circCCNY enhances lenvatinib sensitivity and suppresses immune evasion in hepatocellular carcinoma by serving as a scaffold for SMURF1 mediated HSP60 degradation (2025-01-16)
期刊：CANCER LETTERS
DOI：10.1016/j.canlet.2025.217470
影响因子 ：9.1
引用产品： HuH-7 细胞 , SNU-449 细胞 , Hep 3B2.1-7 细胞 , Hepa 1-6 细胞
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Interaction of STIL with FOXM1 regulates SF3A3 transcription in the hepatocellular carcinoma development (2025-01-17)
期刊：Cell Division
DOI：10.1186/s13008-025-00142-4
影响因子 ：2.8
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞
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Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression (2024-07-03)
期刊：Signal Transduction and Targeted Therapy
DOI：10.1038/s41392-024-01887-0
影响因子 ：40.8
引用产品： Hep 3B2.1-7 细胞
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Remediation of Metal Oxide Nanotoxicity with a Functional Amyloid (2024-04-06)
期刊：Advanced Science
影响因子 ：14.3
引用产品： Hep 3B2.1-7 细胞
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CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis (2024-12-18)
期刊：CANCER RESEARCH
DOI：10.1158/0008-5472.CAN-24-0147
影响因子 ：12.5
引用产品： HuCC-T1 细胞 , RBE 细胞 , HCCC-9810 细胞 , Hep 3B2.1-7 细胞 , HFL1 细胞 , HuH-1 细胞 , HuH-7 细胞
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O-GlcNAcylated RALY Contributes to Hepatocellular Carcinoma Cells Proliferation by Regulating USP22 mRNA Nuclear Export (2024-07-01)
期刊：International Journal of Biological Sciences
影响因子 ：8.2
引用产品： HuH-7 细胞 , THLE-2 细胞 , Hep 3B2.1-7 细胞
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How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study (2024-03-11)
期刊：COMPUTERS IN BIOLOGY AND MEDICINE
DOI：10.1016/j.compbiomed.2024.108260
影响因子 ：7.7
引用产品： HL-7702 [L-02; LO2] 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞
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RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling (2024-02-18)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-04964-8
影响因子 ：7.4
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞 , PLC/PRF/5 细胞 , Li-7 细胞 , THLE-2 细胞
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B cell lymphoma 6 promotes hepatocellular carcinoma progression by inhibiting tumor infiltrating CD4+T cell cytotoxicity through ESM1 (2024-07-01)
期刊：npj Precision Oncology
DOI：10.1038/s41698-024-00625-7
影响因子 ：6.8
引用产品： Hepa 1-6 细胞 , H22 细胞 , Hep53.4 细胞 , Hep 3B2.1-7 细胞
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CREB3L4 promotes hepatocellular carcinoma progression and decreases sorafenib chemosensitivity by promoting RHEB-mTORC1 signaling pathway (2024-01-09)
期刊：iScience
DOI：10.1016/j.isci.2024.108843
影响因子 ：5.8
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞
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PTGES3 proteolysis using the liposomal peptide-PROTAC approach (2024-12-26)
期刊：Biology Direct
DOI：10.1186/s13062-024-00580-0
影响因子 ：5.7
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞
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In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma (2024-10-31)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2024.1482914
影响因子 ：5.7
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞
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TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway (2024-03-12)
期刊：CANCER SCIENCE
影响因子 ：5.7
引用产品： HuH-7 细胞 , SK-Hep-1 细胞 , Hep 3B2.1-7 细胞
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BMP9-ID1 Pathway Attenuates N6-Methyladenosine Levels of CyclinD1 to Promote Cell Proliferation in Hepatocellular Carcinoma (2024-01-12)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.6
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞
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Polyphyllin I exerts anti-hepatocellular carcinoma activity by targeting ZBTB16 to activate the PPARγ/RXRα signaling pathway (2024-08-24)
期刊：Chinese Medicine
DOI：10.1186/s13020-024-00984-0
影响因子 ：5.3
引用产品： SK-Hep-1 细胞 , Hep 3B2.1-7细胞专用培养基 , SK-Hep-1细胞专用培养基 , Hep 3B2.1-7 细胞
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Oncolytic Activity of Sindbis Virus with the Help of GM-CSF in Hepatocellular Carcinoma (2024-06-29)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：4.9
引用产品： Hep 3B2.1-7 细胞 , C2C12 细胞 , Hep G2 细胞 , LX-2 细胞 , HuH-7 细胞
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The prognostic significance and potential mechanism of PFDN4 in hepatocellular carcinoma (2024-12-06)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.113761
影响因子 ：4.8
引用产品： THLE-2 细胞 , MHCC97-L 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞 , HLF-a 细胞 , SNU-449 细胞
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Obovatol inhibits proliferation, invasion and immune escape of hepatocellular carcinoma cells through modulating the JAK/STST3/PD-L1 pathway (2024-08-14)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112775
影响因子 ：4.8
引用产品： Hep 3B2.1-7 细胞 , DMEM高糖 培养基 , HuH-7 细胞 , 青霉素-链霉素溶液（双抗），100×
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Injectable Hydrogel-Encapsulating Pickering Emulsion for Overcoming Lenvatinib-Resistant Hepatocellular Carcinoma via Cuproptosis Induction and Stemness Inhibition (2024-08-26)
期刊：Polymers
影响因子 ：4.7
引用产品： HL-7702 [L-02; LO2] 细胞 , Hep 3B2.1-7 细胞 , Hepa 1-6 细胞 , HuH-7 细胞
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Bombinin-BO1 induces hepatocellular carcinoma cell cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis (2024-06-26)
期刊：iScience
DOI：10.1016/j.isci.2024.110382
影响因子 ：4.6
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞
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Exosomal miR-3174 induced by hypoxia promotes angiogenesis and metastasis of hepatocellular carcinoma by inhibiting HIPK3 (2024-01-19)
期刊：iScience
DOI：10.1016/j.isci.2024.108955
影响因子 ：4.6
引用产品： Hep 3B2.1-7 细胞 , HCCLM3 细胞 , 293T [HEK-293T] 细胞
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UBA2 SUMOylates NQO1 and promotes the proliferation of hepatocellular carcinoma by modulating the MAPK pathway (2024-07-16)
期刊：CANCER SCIENCE
影响因子 ：4.5
引用产品： SNU-368 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞 , SK-Hep-1 细胞
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Therapeutic potential of tLyp-1-EV-shCTCF in inhibiting liver cancer stem cell self-renewal and immune escape via SALL3 modulation in hepatocellular carcinoma (2024-08-25)
期刊：Translational Oncology
DOI：10.1016/j.tranon.2024.102048
影响因子 ：4.5
引用产品： 293T [HEK-293T] 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞
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Circ_0027791 contributes to the growth and immune evasion of hepatocellular carcinoma via the miR-496/programmed cell death ligand 1 axis in an m6A-dependent manner (2024-03-28)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.5
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞 , MHCC97-L细胞专用培养基 , Hep 3B2.1-7细胞专用培养基 , HuH-7细胞专用培养基
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The extract of an herbal medicine Chebulae fructus inhibits hepatocellular carcinoma by suppressing the Apelin/APJ system (2024-05-30)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2024.1413463
影响因子 ：4.4
引用产品： Hep G2 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞 , HCCLM3 细胞 , Hep 3B2.1-7 细胞
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The Potential of the lncRNAs ADAMTSL4-AS1, AC067931 and SOCS2-AS1 in Peripheral Blood Mononuclear Cells as Novel Diagnostic Biomarkers for Hepatitis B Virus-Associated Hepatocellular Carcinoma (2024-06-28)
期刊：Journal of Hepatocellular Carcinoma
影响因子 ：4.2
引用产品： HepG2.215 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞 , Hep G2 细胞 , LX-2 细胞
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Psilostachyin C reduces malignant properties of hepatocellular carcinoma cells by blocking CREBBP-mediated transcription of GATAD2B (2024-04-11)
期刊：FUNCTIONAL & INTEGRATIVE GENOMICS
DOI：10.1007/s10142-024-01353-8
影响因子 ：3.9
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞 , MEM（含NEAA） 培养基 , 特级胎牛血清
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miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2 (2024-02-23)
期刊：CANCER BIOLOGY & THERAPY
DOI：10.1080/15384047.2024.2315651
影响因子 ：3.6
引用产品： HL-7702 [L-02; LO2] 细胞 , HuH-7 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞 , SMMC-7721 细胞 , SK-Hep-1 细胞
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Identification of Clinical Value and Biological Effects of XIRP2 Mutation in Hepatocellular Carcinoma (2024-08-19)
期刊：Biology-Basel
影响因子 ：3.6
引用产品： SK-Hep-1 细胞 , Hep G2 细胞 , HuH-7 细胞 , HuH-1 细胞 , Hep 3B2.1-7 细胞
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Atractylenolide II regulates the proliferation, ferroptosis, and immune escape of hepatocellular carcinoma cells by inactivating the TRAF6/NF-κB pathway (2024-05-06)
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-024-03046-2
影响因子 ：3.6
引用产品： DMEM高糖 培养基 , Hep 3B2.1-7 细胞 , 青霉素-链霉素溶液（双抗），100× , HuH-7 细胞
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Exosomal IGFBP2 derived from highly metastatic promotes hepatocellular carcinoma metastasis by inducing epithelial mesenchymal transition (2024-03-14)
期刊：GENE
DOI：10.1016/j.gene.2024.148374
影响因子 ：3.5
引用产品： HL-7702 [L-02; LO2] 细胞 , Hep 3B2.1-7 细胞
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Sterigmatocystin induces autophagic and apoptotic cell death of liver cancer cells via downregulation of XIAP (2024-04-17)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e29567
影响因子 ：3.4
引用产品： HL-7702 [L-02; LO2] 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞
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LINC02987 suppression hepatocellular carcinoma progression by modulating autophagy via the miR-338-3p/ATG12 axis (2024-12-31)
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2024.114398
影响因子 ：3.3
引用产品： HuH-7 细胞 , Li-7 细胞 , THLE-2 细胞 , SK-Hep-1 细胞 , Hep 3B2.1-7 细胞 , Hep G2 细胞
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Identification and Therapeutic Targeting of METTL8-Mediated Lenvatinib Resistance in Hepatocellular Carcinoma Using Rabdosiin (2024-12-18)
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2024.114389
影响因子 ：3.3
引用产品： 磷酸盐缓冲液（PBS） 1× , Hep G2 细胞 , Hep 3B2.1-7 细胞
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Liquidambaric acid inhibits the proliferation of hepatocellular carcinoma cells by targeting PPARα-RXRα to down-regulate fatty acid metabolism (2024-07-25)
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2024.117042
影响因子 ：3.3
引用产品： Li-7 细胞 , Annexin V-FITC/PI荧光双染细胞凋亡检测试剂盒 , Hep G2 细胞 , HuH-7 细胞 , PLC/PRF/5 细胞 , Hep 3B2.1-7 细胞
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IL-21- and CXCL9-engineered GPC3-specific CAR-T cells combined with PD-1 blockade enhance cytotoxic activities against hepatocellular carcinoma (2024-08-28)
期刊：CLINICAL AND EXPERIMENTAL MEDICINE
DOI：10.1007/s10238-024-01473-2
影响因子 ：3.2
引用产品： Hep 3B2.1-7 细胞
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Cancer-associated fibroblasts-derived exosomal ZNF250 promotes the proliferation, migration, invasion, and immune escape of hepatocellular carcinoma cells by transcriptionally activating PD-L1 (2024-09-09)
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 ：3.2
引用产品： DMEM高糖 培养基 , 青霉素-链霉素溶液（双抗），100× , Hep 3B2.1-7 细胞 , 特级胎牛血清 , THLE-2 细胞 , RPMI-1640 培养基
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STAMBPL1, transcriptionally regulated by SREBP1, promotes malignant behaviors of hepatocellular carcinoma cells via Wnt/β-catenin signaling pathway (2024-08-16)
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23801
影响因子 ：3.0
引用产品： PLC/PRF/5 细胞 , Hep 3B2.1-7 细胞
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Matrine inhibits cell proliferation, invasion, and stem cell formation in hepatocellular carcinoma by regulating the ELAVL1/RBM3-mediated Wnt/β-catenin signaling pathway (2024-01-23)
期刊：Chemical Biology & Drug Design
影响因子 ：3.0
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞 , MEM 培养基 , DMEM高糖 培养基
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Circ_0084615 promotes epithelial-mesenchymal transition-mediated tumor progression in hepatocellular carcinoma (2024-06-03)
期刊：Annals of Gastroenterological Surgery
影响因子 ：2.9
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , THLE-2 细胞 , BEL-7405 细胞 , SK-Hep-1 细胞
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Farrerol suppresses epithelial-mesenchymal transition in hepatocellular carcinoma via suppression of TGF-β1/Smad2/3 signaling (2024-11-08)
期刊：PATHOLOGY RESEARCH AND PRACTICE
影响因子 ：2.9
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞 , RPMI-1640 培养基 , MTT溶液（5 mg/mL）
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ZSCAN16 expedites hepatocellular carcinoma progression via activating TBC1D31 (2024-11-07)
期刊：Cell Division
DOI：10.1186/s13008-024-00135-9
影响因子 ：2.8
引用产品： Hep 3B2.1-7 细胞 , MEM（含NEAA） 培养基
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Overexpression of PLK1 Molecule Following Incomplete Thermal Ablation Promotes the Proliferation and Invasion of Residual Hepatocellular Carcinoma (2024-05-23)
期刊：MOLECULAR BIOTECHNOLOGY
DOI：10.1007/s12033-024-01181-y
影响因子 ：2.6
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞
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Comprehensive transcriptomic analysis identifies cholesterol transport pathway as a therapeutic target of porcine epidemic diarrhea coronavirus (2024-11-23)
期刊：VIRUS RESEARCH
DOI：10.1016/j.virusres.2024.199502
影响因子 ：2.5
引用产品： Hep G2 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞 , Li-7 细胞 , LLC-PK1 细胞
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LINC00665 target let-7i/HMGA1 promotes the proliferation and invasion of hepatoma cells (2024-02-07)
期刊：MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
DOI：10.1016/j.mrfmmm.2024.111852
影响因子 ：2.3
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞
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E2F8—TPX2 axis regulates glycolysis and angiogenesis to promote progression and reduce chemosensitivity of liver cancer (2024-09-21)
期刊：CYTOTECHNOLOGY
DOI：10.1007/s10616-024-00655-w
影响因子 ：2.0
引用产品： 人脐静脉内皮细胞 , HuH-7 细胞 , LX-2 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞 , 293T [HEK-293T] 细胞
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hsa_circ_0072309 Inhibits Oncogenesis in Hepatocellular Carcinoma by Epigenetic Activation of its Host Gene (2024-09-16)
期刊：CELL BIOCHEMISTRY AND BIOPHYSICS
DOI：10.1007/s12013-024-01330-9
影响因子 ：1.8
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞 , THLE-2 细胞
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Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT (2023-10-22)
期刊：Advanced Science
影响因子 ：15.1
引用产品： HCCLM3 细胞 , Hep G2 细胞 , HuH-7 细胞 , BEL-7404 细胞 , Hep 3B2.1-7 细胞 , PLC/PRF/5 细胞 , 293T [HEK-293T] 细胞
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ATR-dependent ubiquitin-specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance (2023-12-20)
期刊：MedComm
DOI：10.1002/mco2.463
影响因子 ：9.9
引用产品： 293T [HEK-293T] 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞
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The deubiquitinating enzyme USP19 facilitates hepatocellular carcinoma progression through stabilizing YAP (2023-10-12)
期刊：CANCER LETTERS
DOI：10.1016/j.canlet.2023.216439
影响因子 ：9.7
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞
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Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma (2023-05-03)
期刊：Cell Death & Disease
DOI：10.1038/s41419-023-05831-y
影响因子 ：9.0
引用产品： Hep 3B2.1-7 细胞
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5′-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I (2023-03-28)
期刊：Frontiers of Medicine
影响因子 ：8.1
引用产品： HuH-7 细胞 , SK-Hep-1 细胞 , Hep 3B2.1-7 细胞 , Li-7 细胞
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RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4 (2023-12-01)
期刊：ONCOGENE
DOI：10.1038/s41388-023-02902-4
影响因子 ：8.0
引用产品： Hep 3B2.1-7 细胞 , Hep G2 细胞 , HuH-7 细胞
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Targeting DDX11 promotes PARP inhibitor sensitivity in hepatocellular carcinoma by attenuating BRCA2-RAD51 mediated homologous recombination (2023-11-25)
期刊：ONCOGENE
DOI：10.1038/s41388-023-02898-x
影响因子 ：8.0
引用产品： MHCC97-L 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞
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JMJD6–BRD4 complex stimulates lncRNA HOTAIR transcription by binding to the promoter region of HOTAIR and induces radioresistance in liver cancer stem cells (2023-10-25)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04394-y
影响因子 ：7.4
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞 , 293T [HEK-293T] 细胞
-
Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma (2023-04-28)
期刊：Cell Death Discovery
DOI：10.1038/s41420-023-01405-1
影响因子 ：7.0
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞 , SK-Hep-1 细胞
-
KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2 (2023-05-19)
期刊：iScience
DOI：10.1016/j.isci.2023.106914
影响因子 ：5.8
引用产品： Hep 3B2.1-7 细胞 , Hep G2 细胞 , HuH-7 细胞
-
The anti-hepatocellular carcinoma effect of Aidi injection was related to the synergistic action of cantharidin, formononetin, and isofraxidin through BIRC5, FEN1, and EGFR (2023-09-25)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
引用产品： Li-7 细胞 , Hep 3B2.1-7 细胞
-
Detection of CSTF2 by nano fluorescent probe and its correlation with malignant biological characteristics in liver cancer (2023-11-15)
期刊：American Journal of Cancer Research
DOI：PMID:38058835
影响因子 ：5.3
引用产品： HL-7702 [L-02; LO2] 细胞 , HCCLM3 细胞 , Hep 3B2.1-7 细胞
-
Upregulation of FAM134B inhibits endoplasmic reticulum stress-related degradation protein expression and promotes hepatocellular carcinogenesis (2023-09-20)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：5.3
引用产品： HL-7702 [L-02; LO2] 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞
-
Chaetocochin J exhibits anti-hepatocellular carcinoma effect independent of hypoxia (2023-06-25)
期刊：BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2023.106701
影响因子 ：5.1
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞
-
Asymmetric total synthesis and anti-hepatocellular carcinoma profile of enantiopure euphopilolide and jolkinolide E (2023-06-22)
期刊：BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2023.106688
影响因子 ：5.1
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞
-
Circ_0007429/miR-637/TRIM71/Ago2 axis participates in the regulation of proliferation, migration, invasion, apoptosis, and aerobic glycolysis of HCC (2023-03-15)
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23526
影响因子 ：4.6
引用产品： HuH-7 细胞 , Hep G2 细胞 , HCCLM3 细胞 , SK-Hep-1 细胞 , Hep 3B2.1-7 细胞 , MHCC97-L 细胞
-
Hepatoprotective effects of aspirin on diethylnitrosamine-induced hepatocellular carcinoma in rats by reducing inflammation levels and PD-L1 expression (2023-12-04)
期刊：Scientific Reports
DOI：10.1038/s41598-023-48812-z
影响因子 ：4.6
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞 , DMEM高糖 培养基
-
LINC00886 Facilitates Hepatocellular Carcinoma Tumorigenesis by Sequestering microRNA-409-3p and microRNA-214-5p (2023-06-07)
期刊：Journal of Hepatocellular Carcinoma
影响因子 ：4.1
引用产品： LX-2 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞
-
A Nucleotide Metabolism-Related Gene Signature for Risk Stratification and Prognosis Prediction in Hepatocellular Carcinoma Based on an Integrated Transcriptomics and Metabolomics Approach (2023-10-30)
期刊：Metabolites
影响因子 ：4.1
引用产品： HuH-7 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞
-
Ellagic acid inhibits tumor growth and potentiates the therapeutic efficacy of sorafenib in hepatocellular carcinoma (2023-12-18)
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e23931
影响因子 ：4.0
引用产品： Annexin V-APC/PI荧光双染细胞凋亡检测试剂盒 , HuH-7 细胞 , Hep 3B2.1-7 细胞
-
Circular RNA circBNC2 facilitates glycolysis and stemness of hepatocellular carcinoma through the miR-217/high mobility group AT-hook 2 (HMGA2) axis. (2023-06-09)
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e17120
影响因子 ：4.0
引用产品： HL-7702 [L-02; LO2] 细胞 , HuH-7 细胞 , HCCLM3 细胞 , Hep 3B2.1-7 细胞
-
The abrogation of GRP78 sensitizes liver cancer cells to lysionotin by enhancing ER stress-mediated pro-apoptotic pathway (2023-06-16)
期刊：CELL STRESS & CHAPERONES
DOI：10.1007/s12192-023-01358-5
影响因子 ：3.8
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞
-
HuR-induced circ_0082319 contributes to hepatocellular carcinoma by elevating PTK2 through miR-505-3p (2023-10-25)
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-023-02793-y
影响因子 ：3.6
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞 , MHCC97-L细胞专用培养基 , Hep 3B2.1-7细胞专用培养基 , HuH-7细胞专用培养基
-
Active compounds and potential targets of Shuganning injection in the treatment of hepatocellular carcinoma by network pharmacology and in vitro validation (2023-03-04)
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-023-02432-6
影响因子 ：3.6
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞
-
LncRNA FAM13A-AS1, transcriptionally regulated by PHOX2B, modulates hepatocellular carcinoma chemoresistance via stabilizing PPARγ (2023-06-16)
期刊：GENE
DOI：10.1016/j.gene.2023.147570
影响因子 ：3.5
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞
-
FKBP11 upregulation promotes proliferation and migration in hepatocellular carcinoma (2023-06-08)
期刊：Cancer Biomarkers
影响因子 ：3.1
引用产品： Hep G2 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞 , HL-7702 [L-02; LO2] 细胞
-
NFYAv1 is a Tumor-Promoting Transcript Associated with Poor Prognosis of Hepatocellular Carcinoma (2023-01-21)
期刊：MEDICAL SCIENCE MONITOR
影响因子 ：3.1
引用产品： SK-Hep-1 细胞 , Hep 3B2.1-7 细胞
-
Transcriptome-Wide Dynamics of m7G-Related LncRNAs during the Progression from HBV Infection to Hepatocellular Carcinoma (2023-12-19)
期刊：Frontiers in Bioscience-Landmark
影响因子 ：3.1
引用产品： Hep 3B2.1-7 细胞
-
Silencing of keratin 15 impairs viability and mobility while facilitating the doxorubicin chemosensitivity by inactivating the β?catenin pathway in liver cancer (2023-08-30)
期刊：Oncology Letters
影响因子 ：2.9
引用产品： HuH-7 细胞 , PLC/PRF/5 细胞 , Hep 3B2.1-7 细胞 , Hep G2 细胞 , Li-7 细胞 , RPMI-1640 培养基 , DMEM高糖 培养基 , 青霉素-链霉素溶液 (双抗)，100×
-
Metformin promotes ferroptosis and sensitivity to sorafenib in hepatocellular carcinoma cells via ATF4/STAT3 (2023-06-16)
期刊：MOLECULAR BIOLOGY REPORTS
DOI：10.1007/s11033-023-08492-4
影响因子 ：2.8
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞
-
Activating the Hippo pathway by nevadensin overcomes Yap-drived resistance to sorafenib in hepatocellular carcinoma (2023-05-27)
期刊：Discover Oncology
DOI：10.1007/s12672-023-00699-y
影响因子 ：2.2
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞
-
Inhibitory Effect of Hernandezine on the Proliferation of Hepatocellular Carcinoma (2023-02-01)
期刊：BIOLOGICAL & PHARMACEUTICAL BULLETIN
影响因子 ：2.0
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞
-
Polygonatum sibiricum Polysaccharide Inhibited Liver Cancer in a Simulated Tumor Microenvironment by Eliminating TLR4/STAT3 Pathway (2023-09-01)
期刊：BIOLOGICAL & PHARMACEUTICAL BULLETIN
影响因子 ：2.0
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞 , 人骨髓树突状细胞 (成熟DC细胞)
-
ALKBH5/MAP3K8 axis regulates PD-L1+ macrophage infiltration and promotes hepatocellular carcinoma progression (2022-08-01)
期刊：International Journal of Biological Sciences
影响因子 ：10.8
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞 , SK-Hep-1 细胞 , Hep G2 细胞 , H22 细胞 , THP-1 细胞
-
S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway (2022-08-16)
期刊：Cell Reports
DOI：10.1016/j.celrep.2022.111194
影响因子 ：10.0
引用产品： SK-Hep-1 细胞 , Hep G2 细胞 , 293T [HEK-293T] 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞
-
Rational engineering of adeno-associated virus capsid enhances human hepatocyte tropism and reduces immunogenicity (2022-09-22)
期刊：CELL PROLIFERATION
影响因子 ：8.8
引用产品： 293T [HEK-293T] 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞 , MRC-5 细胞 , Hepa 1-6 细胞 , Renca [RenCa] 细胞
-
SGOL2 is a novel prognostic marker and fosters disease progression via a MAD2-mediated pathway in hepatocellular carcinoma (2022-11-15)
期刊：Biomarker Research
DOI：10.1186/s40364-022-00422-z
影响因子 ：8.6
引用产品： SK-Hep-1 细胞 , Hep 3B2.1-7 细胞
-
Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression (2022-01-12)
期刊：CELLULAR AND MOLECULAR LIFE SCIENCES
DOI：10.1007/s00018-021-04118-9
影响因子 ：8.0
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞
-
Hepatic stellate cell‐released CXCL1 aggravates HCC malignant behaviors through the MIR4435‐2HG/miR‐506‐3p/TGFB1 axis (2022-12-04)
期刊：CANCER SCIENCE
影响因子 ：6.5
引用产品： Hep 3B2.1-7 细胞 , LX-2 细胞
-
Transfer RNA‐derived fragment 5′tRF‐Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen‐related cell adhesion molecule 1 (2022-08-16)
期刊：CANCER SCIENCE
影响因子 ：6.5
引用产品： Hep 3B2.1-7 细胞 , 293T/17 细胞 , Li-7 细胞 , HuH-7 细胞 , SK-Hep-1 细胞 , Hep G2 细胞
-
VEZF1, destabilized by STUB1, affects cellular growth and metastasis of hepatocellular carcinoma by transcriptionally regulating PAQR4 (2022-10-14)
期刊：CANCER GENE THERAPY
DOI：10.1038/s41417-022-00540-8
影响因子 ：5.9
引用产品： SK-Hep-1 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞
-
Identification and Characterization of Cell Lines HepG2, Hep3B217 and SNU387 as Models for Porcine Epidemic Diarrhea Coronavirus Infection (2022-12-10)
期刊：Viruses-Basel
影响因子 ：5.8
引用产品： HuH-7 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞 , BHK-21 [C-13] 细胞 , Li-7 细胞
-
Establishment of Prognostic Signatures of N6-Methyladenosine-Related lncRNAs and Their Potential Functions in Hepatocellular Carcinoma Patients (2022-06-06)
期刊：Frontiers in Oncology
影响因子 ：5.7
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞
-
Proteoglycan-4 predicts good prognosis in patients with hepatocellular carcinoma receiving transcatheter arterial chemoembolization and inhibits cancer cell migration in vitro (2022-11-11)
期刊：Frontiers in Oncology
影响因子 ：5.7
引用产品： Hep 3B2.1-7 细胞 , HuH-1 细胞 , 293T [HEK-293T] 细胞
-
Exosomes Derived from microRNA-27a-3p Overexpressing Mesenchymal Stem Cells Inhibit the Progression of Liver Cancer through Suppression of Golgi Membrane Protein 1 (2022-12-07)
期刊：Stem Cells International
影响因子 ：5.1
引用产品： Hep G2 细胞 , MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞 , HL-7702 [L-02; LO2] 细胞
-
SLC39A10 Upregulation Predicts Poor Prognosis, Promotes Proliferation and Migration, and Correlates with Immune Infiltration in Hepatocellular Carcinoma (2022-11-14)
期刊：Journal of Hepatocellular Carcinoma
影响因子 ：5.0
引用产品： MHCC97-L 细胞 , HCCLM3 细胞 , Hep G2 细胞 , HL-7702 [L-02; LO2] 细胞 , PLC/PRF/5 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞
-
Long noncoding RNA HULC regulates the NF-κB pathway and represents a promising prognostic biomarker in liver cancer (2022-10-10)
期刊：Cancer Medicine
影响因子 ：4.7
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞 , LX-2 细胞
-
LncRNA AC026401.3 interacts with OCT1 to intensify sorafenib and lenvatinib resistance by activating E2F2 signaling in hepatocellular carcinoma (2022-09-06)
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2022.113335
影响因子 ：4.1
引用产品： Hep 3B2.1-7 细胞 , Hep G2 细胞 , HuH-7 细胞 , MHCC97-L 细胞 , PLC/PRF/5 细胞 , MIHA 细胞
-
FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in?vitro and in?vivo (2022-11-22)
期刊：Oncology Letters
影响因子 ：3.1
引用产品： HuH-7 细胞 , HCCLM3 细胞 , MHCC97-L 细胞 , Hep 3B2.1-7 细胞
-
Role of SLC39A6 in the development and progression of liver cancer (2022-01-11)
期刊：Oncology Letters
影响因子 ：2.9
引用产品： Hep G2 细胞 , Hep 3B2.1-7 细胞
-
Activation of YAP1 by STK25 contributes to the progression of hepatocellular carcinoma (2022-04-06)
期刊：TISSUE & CELL
DOI：10.1016/j.tice.2022.101797
影响因子 ：2.6
引用产品： MHCC97-L 细胞 , Hep 3B2.1-7 细胞 , SNU-182 细胞
-
LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway (2021-11-27)
期刊：Cellular & Molecular Biology Letters
DOI：10.1186/s11658-021-00295-4
影响因子 ：8.3
引用产品： HCCLM3 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞 , SK-Hep-1 细胞
-
Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α (2021-09-01)
期刊：Frontiers in Cell and Developmental Biology
影响因子 ：5.5
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞
-
The bioactive ingredients in Actinidia chinensis Planch. Inhibit liver cancer by inducing apoptosis (2021-08-21)
期刊：Journal Of Ethnopharmacology
影响因子 ：5.4
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞
-
Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways (2021-02-09)
期刊：Plos Computational Biology
DOI：10.1371/journal.pcbi.1008696
影响因子 ：4.3
引用产品： HCC 94 [HCC941122] 细胞 , Hep G2 细胞 , Hep 3B2.1-7 细胞
-
ZSCAN16-AS1 expedites hepatocellular carcinoma progression via modulating the miR-181c-5p/SPAG9 axis to activate the JNK pathway (2021-06-07)
期刊：Cell Cycle
DOI：10.1080/15384101.2021.1919828
影响因子 ：4.3
引用产品： HCCLM3 细胞 , Hep 3B2.1-7 细胞 , HuH-7 细胞
-
Targeting Hedgehog signalling in CD133-positive hepatocellular carcinoma: improving Lenvatinib therapeutic efficiency (2021-03-17)
期刊：MEDICAL ONCOLOGY
DOI：10.1007/s12032-021-01487-w
影响因子 ：3.4
引用产品： Hep G2 细胞 , SK-Hep-1 细胞 , Hep 3B2.1-7 细胞
-
Lidocaine Inhibits Hepatocellular Carcinoma Development by Modulating circ_ITCH/miR-421/CPEB3 Axis (2021-01-12)
期刊：Digestive Diseases And Sciences
DOI：10.1007/s10620-020-06787-1
影响因子 ：3.1
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞
-
CKS1B promotes the progression of hepatocellular carcinoma by activating JAK/STAT3 signal pathway (2021-07-14)
期刊：Animal Cells and Systems
DOI：10.1080/19768354.2021.1953142
影响因子 ：2.9
引用产品： Hep 3B2.1-7 细胞 , HuH-7 细胞
-
Propofol enhances the lethality of cisplatin on liver cancer cells by up-regulating miR-195-5p (2021-11-19)
期刊：Tissue & Cell
DOI：10.1016/j.tice.2021.101680
影响因子 ：2.6
引用产品： HuH-7 细胞 , Hep 3B2.1-7 细胞 , HuH-7细胞专用培养基 , Hep 3B2.1-7细胞专用培养基
-
An NAD+ -Dependent Deacetylase SIRT7 Promotes HCC Development Through Deacetylation of USP39 (2020-07-09)
期刊：iScience
DOI：10.1016/j.isci.2020.101351
影响因子 ：5.8
引用产品： Hep 3B2.1-7 细胞
-
LncRNA KCNQ1OT1 inhibits the radiosensitivity and promotes the tumorigenesis of hepatocellular carcinoma via the miR-146a-5p/ACER3 axis (2020-09-16)
期刊：Cell Cycle
DOI：10.1080/15384101.2020.1809259
影响因子 ：4.3
引用产品： HuH-6 细胞 , Hep 3B2.1-7 细胞 , SK-Hep-1 细胞 , SNU-182 细胞
-
Sp2 promotes invasion and metastasis of hepatocellular carcinoma by targeting TRIB3 protein (2020-03-11)
期刊：Cancer Medicine
影响因子 ：4.0
引用产品： Hep G2 细胞 , HuH-7 细胞 , Hep 3B2.1-7 细胞
-
USP27-mediated Cyclin E stabilization drives cell cycle progression and hepatocellular tumorigenesis (2018-03-02)
期刊：Oncogene
影响因子 ：8.0
引用产品： Hep 3B2.1-7 细胞
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