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产品概述
| 名称 | AC16 (人心肌细胞) (STR鉴定正确) |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 成纤维细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | AC16 Human Cardiomyocytes can be serially passaged and can differentiate when cultured in mitogen-free medium. The cells may be used to study developmental regulation of cardiomyocytes. |
| 组织来源 | 人心脏组织 |
| 细胞类型 | 杂交细胞系 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | 24.49 hours (PubMed=15913645) |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 9,11,12 D2S1338 20,23,26 D3S1358 17,18 D5S818 9,11 D7S820 10,11,12 D8S1179 14,15 D13S317 12,13 D16S539 11,13 D18S51 12,17 D19S433 15,15.2 D21S11 32.2 FGA 21,25 PentaD 2.2,9 PentaE 7,12,16 TH01 7,8,9.3 TPOX 11 vWA 16,18 D6S1043 14,17 D12S391 17.3,18,21 D2S441 10,14 -
STR鉴定图
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参考文献
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Long-chain chlorinated paraffins (LCCPs) exposure causes senescence and inflammatory damage in cardiomyocytes (2025-01-22)
期刊：JOURNAL OF ENVIRONMENTAL MANAGEMENT
DOI：10.1016/j.jenvman.2025.124166
影响因子 ：8.0
引用产品： AC16 细胞 , H9c2(2-1) 细胞
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Evolocumab attenuates myocardial ischemia/reperfusion injury by blocking PCSK9/LIAS-mediated cuproptosis of cardiomyocytes (2025-02-11)
期刊：BASIC RESEARCH IN CARDIOLOGY
DOI：10.1007/s00395-025-01100-5
影响因子 ：7.5
引用产品： AC16 细胞
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Lycium barbarum glycopeptide ameliorates aging phenotypes and enhances cardiac metabolism by activating the PINK1/Parkin-mediated mitophagy pathway in D-galactose-induced mice (2025-01-18)
期刊：EXPERIMENTAL GERONTOLOGY
DOI：10.1016/j.exger.2025.112686
影响因子 ：3.3
引用产品： AC16 细胞
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Astragalus polyphenols attenuates doxorubicin-induced cardiotoxicity by activating the PI3K/AKT/NRF2 pathway (2025-02-25)
期刊：PLoS One
DOI：10.1371/journal.pone.0319067
影响因子 ：2.9
引用产品： AC16 细胞 , H9c2(2-1) 细胞
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Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis (2025-02-04)
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-025-02333-9
影响因子 ：2.8
引用产品： AC16 细胞
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ALDH2 mediates the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on improving cardiac remodeling (2024-10-26)
期刊：Cardiovascular Diabetology
DOI：10.1186/s12933-024-02477-8
影响因子 ：8.5
引用产品： H9c2(2-1) 细胞 , AC16 细胞
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Comprehensive bioinformatics analysis reveals the role of cuproptosis-related gene Ube2d3 in myocardial infarction (2024-02-19)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2024.1353111
影响因子 ：5.7
引用产品： AC16 细胞
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PPARA ameliorates sepsis-induced myocardial injury via promoting macrophage M2 polarization by interacting with DUSP1 (2024-05-18)
期刊：Regenerative Therapy
DOI：10.1016/j.reth.2024.04.017
影响因子 ：4.3
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Identification of immune feature genes and intercellular profiles in diabetic cardiomyopathy (2024-10-15)
期刊：World Journal of Diabetes
影响因子 ：4.2
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Hypoxia-induced circRNAs encoded by PPARA are highly expressed in human cardiomyocytes and are potential clinical biomarkers of acute myocardial infarction (2024-03-12)
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-024-01753-3
影响因子 ：4.2
引用产品： AC16 细胞
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Application of angiogenesis-related genes associated with immune infiltration in the molecular typing and diagnosis of acute myocardial infarction (2024-06-14)
期刊：Aging-US
影响因子 ：3.9
引用产品： AC16 细胞
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Comprehensive analysis of hypoxia-related genes in diagnosis and immune infiltration in acute myocardial infarction: based on bulk and single-cell RNA sequencing data (2024-08-21)
期刊：Frontiers in Molecular Biosciences
DOI：10.3389/fmolb.2024.1448705
影响因子 ：3.9
引用产品： AC16 细胞
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Chlorogenic acid attenuates cardiac hypertrophy via up-regulating Sphingosine-1-phosphate receptor1 to inhibit endoplasmic reticulum stress (2024-02-19)
期刊：ESC Heart Failure
影响因子 ：3.8
引用产品： AC16 细胞
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Quercetin Alleviates LPS-Stimulated Myocardial Injury through Regulating ALOX5/PI3K/AKT Pathway in Sepsis (2024-07-28)
期刊：Cardiovascular Toxicology
DOI：10.1007/s12012-024-09901-1
影响因子 ：3.4
引用产品： AC16 细胞
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miR-1268a Regulates Fatty Acid Metabolism by Targeting CD36 in Angiotensin II-induced Heart Failure (2024-04-15)
期刊：CELL BIOCHEMISTRY AND BIOPHYSICS
DOI：10.1007/s12013-024-01268-y
影响因子 ：2.6
引用产品： AC16 细胞 , 青霉素-链霉素溶液（双抗），100× , DMEM/F12 培养基
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CEAM is a mitochondrial-localized, amyloid-like motif-containing microprotein expressed in human cardiomyocytes (2024-10-05)
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2024.150737
影响因子 ：2.5
引用产品： AC16 细胞
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METTL14 Promotes Lipopolysaccharide-Induced Myocardial Damage via m6A-Dependent Stabilization of TRPM7 mRNA (2024-11-30)
期刊：International Heart Journal
影响因子 ：1.2
引用产品： 293T [HEK-293T] 细胞 , DMEM/F12（含HEPES） 培养基 , AC16 细胞
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Circular single-stranded DNA as switchable vector for gene expression in mammalian cells (2023-10-20)
期刊：Nature Communications
DOI：10.1038/s41467-023-42437-6
影响因子 ：16.6
引用产品： B16 细胞 , MCF7 [MCF-7] 细胞 , AC16 细胞 , U-87 MG 细胞 , Hela 细胞 , HELF 细胞 , 293T [HEK-293T] 细胞 , Hepa 1-6 细胞 , NCTC clone 929 [L cell, L-929] 细胞 , A549 [A-549] 细胞 , 5637 细胞 , Ishikawa 细胞 , LoVo 细胞
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