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产品概述
| 名称 | SUM149PT (人乳腺癌细胞) (STR鉴定正确) |
| 别称 | SUM-149PT; SUM 149PT; SUM149-PT; SUM149; SUM-149; SUM 149; 149 PT; 149PT; BrCL12 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | The SUM149PT cell line was developed from Invasive Ductal Carcinoma from a patient with ER negative, PR negative and Her2 positive (not activated) inflammatory breast cancer. The cell line is immortal and expresses luminal cytokeratins 8, 18, and 19, which is consistent with their origin from luminal breast epithelial cells. SUM149PT has been known to form tumors in nude mice. |
| 年龄（性别） | 女性；40岁 |
| 组织来源 | 乳腺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 乳腺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | 48 hours |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 20 D3S1358 17 D5S818 11 D7S820 11 D8S1179 14,16 D13S317 12 D16S539 11 D18S51 14,15 D19S433 12,14 D21S11 28,31.2 FGA 29 PentaD 8,9 PentaE 11 TH01 9.3 TPOX 9 vWA 16,18 D6S1043 18 D12S391 15,18 D2S441 12,16 -
STR鉴定图
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参考文献
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UCHL1 contributes to insensitivity to endocrine therapy in triple-negative breast cancer by deubiquitinating and stabilizing KLF5 (2024-03-11)
作者：Juan Li:1.Department of Breast Surgery, School of Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China. ; Yu Liang:1.Department of Health Management & Institute of Health Management, School of Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China. ; Shijie Zhou:1.State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China. vicjaychou@hotmail.com. ; Jie Chen:1.Department of Breast Surgery, School of Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China. Chenjie20201019@163.com. ; Chihua Wu:1.Department of Breast Surgery, School of Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China. 18749019@qq.com. ;
期刊：UCHL1 contributes to insensitivity to endocrine therapy in triple-negative breast cancer by deubiquitinating and stabilizing KLF5
DOI：10.1186/s13058-024-01800-1
影响因子 ：7.4
引用产品： MCF7 [MCF-7] 细胞 , BT-474 [BT474] 细胞 , SUM149PT 细胞 , MDA-MB-468 细胞
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Mutant p53 and ELK1 co-drive FRA-1 Expression to induce metastasis in breast cancer (2023-11-16)
作者：Sike Hu:1.Tianjin Institute of Medical and Pharmaceutical Sciences, China. ; Manxue Wang:1.Tianjin Institute of Medical and Pharmaceutical Sciences, China. ; Ailing Ji:1.Tianjin Institute of Medical and Pharmaceutical Sciences, China. ; Jie Yang:1.Tianjin Institute of Medical and Pharmaceutical Sciences, China. ; Ruifang Gao:1.Tianjin Institute of Medical and Pharmaceutical Sciences, China. ; Xia Li:1.Tianjin Institute of Medical and Pharmaceutical Sciences, China. ; Lili Sun:1.Tianjin Medicine and Health Research Center, China. ; Jing Wang:1.Tianjin Institute of Medical and Pharmaceutical Sciences, China. ; Ying Zhang:1.Tianjin Medicine and Health Research Center, China. ; Hongbin Liu:1.Tianjin Medicine and Health Research Center, China. ;
期刊：Mutant p53 and ELK1 co-drive FRA-1 Expression to induce metastasis in breast cancer
影响因子 ：3.5
引用产品： MDA-MB-231 细胞 , SUM149PT 细胞 , T-47D 细胞 , MCF7 [MCF-7] 细胞 , MCF 10A 细胞
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