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产品概述
名称 | T-47D (人乳腺管癌细胞) (STR鉴定正确) |
别称 | T-47-D; T47-D; T47D:A; T47D |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | T-47细胞分离自一位54岁乳房侵入性导管癌的女性患者胸水;发现分化的上皮亚株(T-47D)有细胞质连接和17-β-雌二醇及其他类固醇降血钙素的受体,T-47D细胞表达WNT7B癌基因。 |
年龄(性别) | 女性;54岁 |
组织来源 | 乳腺;乳房;导管;来自导管癌肋膜渗出液转移灶 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 乳腺癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~36-46 hours |
致瘤性 | Yes, forms colonies in soft agar. |
受体表达情况 | calcitonin, expressed; androgen receptor, expressed; estrogen receptor, expressed; progesterone receptor, expressed; glucocorticoid receptor, positive, expressed; prolactin, expressed; calcitonin; androgen receptor, positive; progesterone receptor, p |
保藏机构 | ATCC; HTB-133 DSMZ; ACC-739 ECACC; 85102201 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,13 D2S1338 24 D3S1358 15,17 D5S818 12 D7S820 11 D8S1179 13 D13S317 12 D16S539 10 D18S51 17 D19S433 14 D21S11 28,31 FGA 23 PentaD 10,11,12 PentaE 7,14 TH01 6 TPOX 11 vWA 14 D6S1043 19 D12S391 19 D2S441 14 -
STR鉴定图
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参考文献
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Chiral Supramolecular Nanofibers Regulated Tumor-Derived Exosomes Secretion for Constructing an Anti-Tumor Extracellular Microenvironment (2024-02-29)
期刊:Small
影响因子 :13.3
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Extracellular vesicles released by hypoxia-induced tumor-associated fibroblasts impart chemoresistance to breast cancer cells via long noncoding RNA H19 delivery (2024-01-10)
期刊:FASEB JOURNAL
影响因子 :4.8
引用产品: MCF7 [MCF-7] 细胞 , T-47D 细胞 , SK-BR-3 [SKBR3] 细胞 , MDA-MB-231 细胞 , BT-549 细胞 , 293T [HEK-293T] 细胞
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Synthesis of a biocompatible fluorinated multiblock copolymer surfactant for water-in-fluorocarbon droplets and its application in droplet digital polymerase chain reaction (2024-01-09)
期刊:JOURNAL OF APPLIED POLYMER SCIENCE
影响因子 :3.0
引用产品: T-47D 细胞
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A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer (2023-07-05)
期刊:Molecular Cancer
DOI:10.1186/s12943-023-01806-x
影响因子 :37.3
引用产品: MDA-MB-231 细胞 , MDA-MB-468 细胞 , 293T [HEK-293T] 细胞 , Hs 578T 细胞 , MCF7 [MCF-7] 细胞 , T-47D 细胞 , ZR-75-1 细胞 , MCF 10A 细胞
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Novel Self-Assembled Multifunctional Nanoprobes for Second-Near-Infrared-Fluorescence-Image-Guided Breast Cancer Surgery and Enhanced Radiotherapy Efficacy (2023-01-31)
期刊:Advanced Science
影响因子 :15.1
引用产品: MDA-MB-231 细胞 , MDA-MB-231/GFP 细胞 , MCF7 [MCF-7] 细胞 , T-47D 细胞 , MCF 10A 细胞
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Development of a rare earth nanoprobe enables in vivo real-time detection of sentinel lymph node metastasis of breast cancer using NIR-IIb imaging (2023-08-04)
期刊:CANCER RESEARCH
DOI:10.1158/0008-5472.CAN-22-3432
影响因子 :11.2
引用产品: 4T1 细胞 , MDA-MB-231 细胞 , MCF7 [MCF-7] 细胞 , BT-549 细胞 , T-47D 细胞 , SK-BR-3 [SKBR3] 细胞 , BT-474 [BT474] 细胞 , MCF 10A 细胞
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Galangin attenuates doxorubicin-induced cardiotoxicity via activating nuclear factor erythroid 2-related factor 2/heme oxygenase 1 signaling pathway to suppress oxidative stress and inflammation (2023-09-01)
期刊:PHYTOTHERAPY RESEARCH
DOI:10.1002/ptr.7991
影响因子 :7.2
引用产品: MCF7 [MCF-7] 细胞 , T-47D 细胞
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A ddPCR platform based on a microfluidic chip with a dual-function flow-focusing structure for sample-to-result DNA quantification analysis (2023-12-28)
期刊:LAB ON A CHIP
影响因子 :6.1
引用产品: T-47D 细胞
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A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis (2023-03-25)
期刊:Cancer Cell International
DOI:10.1186/s12935-023-02895-w
影响因子 :5.8
引用产品: MCF 10A 细胞 , BT-474 [BT474] 细胞 , BT-549 细胞 , MCF7 [MCF-7] 细胞 , MDA-MB-231 细胞 , MDA-MB-231 细胞 , MDA-MB-453 细胞 , MDA-MB-453 细胞 , T-47D 细胞 , MCF 10A细胞专用培养基 , BT-474 [BT474]细胞专用培养基 , BT-549细胞专用培养基 , MCF7 [MCF-7]细胞专用培养基 , MDA-MB-231细胞专用培养基 (L15) , MDA-MB-231细胞专用培养基 (DMEM) , MDA-MB-453细胞专用培养基 (L15)
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OBHS Drives Abnormal Glycometabolis Reprogramming via GLUT1 in Breast Cancer (2023-04-12)
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :5.6
引用产品: MCF7 [MCF-7] 细胞 , T-47D 细胞 , MDA-MB-231 细胞 , MCF 10A 细胞
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CSF2 upregulates CXCL3 expression in adipocytes to promote metastasis of breast cancer via the FAK signaling pathway (2023-04-18)
期刊:Journal of Molecular Cell Biology
影响因子 :5.5
引用产品: MDA-MB-231 细胞 , BT-549 细胞 , MCF7 [MCF-7] 细胞 , T-47D 细胞 , MCF 10A 细胞 , MCF 10A细胞专用培养基
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ZNF746 promotes M2 macrophage polarisation and favours tumour progression in breast cancer via the Jagged1/Notch pathway (2023-09-18)
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2023.110892
影响因子 :4.8
引用产品: MDA-MB-415 细胞 , T-47D 细胞
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ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop (2023-06-16)
期刊:CARCINOGENESIS
影响因子 :4.7
引用产品: T-47D 细胞 , SK-BR-3 [SKBR3] 细胞 , Leibovitz's L-15 培养基 , McCoy's 5A 培养基
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Upregulation of the ferroptosis-related STEAP3 gene is a specific predictor of poor triple-negative breast cancer patient outcomes (2023-03-31)
期刊:Frontiers in Oncology
影响因子 :4.7
引用产品: MCF 10A 细胞 , MDA-MB-231 细胞 , BT-549 细胞 , MDA-MB-468 细胞 , MCF7 [MCF-7] 细胞 , T-47D 细胞 , BT-474 [BT474] 细胞
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LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway (2023-02-10)
期刊:ONCOLOGY REPORTS
影响因子 :4.2
引用产品: SK-BR-3 [SKBR3] 细胞 , T-47D 细胞 , Leibovitz's L-15 培养基 , McCoy's 5A 培养基
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The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer (2023-09-22)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2023.116698
影响因子 :3.8
引用产品: MCF7 [MCF-7] 细胞 , T-47D 细胞 , MCF 10A 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , DMEM/F12 培养基 , MEM非必需氨基酸溶液 (NEAA),100×
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Mutant p53 and ELK1 co-drive FRA-1 Expression to induce metastasis in breast cancer (2023-11-16)
期刊:FEBS LETTERS
影响因子 :3.5
引用产品: MDA-MB-231 细胞 , SUM149PT 细胞 , T-47D 细胞 , MCF7 [MCF-7] 细胞 , MCF 10A 细胞
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Identification of TFR2 as a novel ferroptosis‑related gene that serves an important role in prognosis and progression of triple‑negative breast cancer (2023-12-05)
期刊:Oncology Letters
影响因子 :2.9
引用产品: MCF 10A 细胞 , T-47D 细胞 , SK-BR-3 [SKBR3] 细胞 , BT-549 细胞 , MDA-MB-468 细胞 , MDA-MB-436 细胞 , MDA-MB-231 细胞 , 马血清 , MEM非必需氨基酸溶液 (NEAA),100×
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Tumor-Promoting Properties of TMEM9A in Breast Cancer Progression via Activating the Wnt/β-Catenin Signaling Pathway (2023-01-01)
期刊:BIOLOGICAL & PHARMACEUTICAL BULLETIN
影响因子 :2.0
引用产品: T-47D 细胞
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Expression of LINC00461 in breast cancer cells and its modulatory effect on miR-607/SLCLA3 axis (2023-05-11)
期刊:TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
影响因子 :0.6
引用产品: MCF 10A 细胞 , MDA-MB-468 细胞 , T-47D 细胞 , MCF7 [MCF-7] 细胞 , MDA-MB-231 细胞 , DMEM/F12 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗),100×
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The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway (2022-09-09)
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2022.116232
影响因子 :4.5
引用产品: T-47D 细胞 , Hs 578T 细胞 , MCF7 [MCF-7] 细胞 , BT-20 细胞 , BT-549 细胞 , MCF 10A 细胞 , RPMI-1640 培养基 , MEM 培养基 , DMEM/F12 培养基
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Selinexor improves the anti-cancer effect of tucidinostat on TP53 wild-type breast cancer (2001-02-20)
期刊:MOLECULAR AND CELLULAR ENDOCRINOLOGY
影响因子 :4.1
引用产品: MCF 10A 细胞 , MCF7 [MCF-7] 细胞 , MDA-MB-175VII 细胞 , T-47D 细胞
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CKAP2L, transcriptionally inhibited by FOXP3, promotes breast carcinogenesis through the AKT/mTOR pathway (2001-02-20)
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2022.113035
影响因子 :3.7
引用产品: SK-BR-3 [SKBR3] 细胞 , T-47D 细胞 , MDA-MB-231 细胞 , MDA-MB-468 细胞 , Leibovitz's L-15 培养基 , McCoy's 5A 培养基
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Cadmium promotes breast cancer cell proliferation, migration and invasion by inhibiting ACSS2/ATG5-mediated autophagy (2001-01-20)
期刊:Environmental Pollution
DOI:10.1016/j.envpol.2021.116504
影响因子 :8.9
引用产品: MCF7 [MCF-7] 细胞 , T-47D 细胞
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Rapamycin antagonizes cadmium-induced breast cancer cell proliferation and metastasis through directly modulating ACSS2 (2008-01-20)
期刊:Ecotoxicology And Environmental Safety
DOI:10.1016/j.ecoenv.2021.112626
影响因子 :6.8
引用产品: MCF7 [MCF-7] 细胞 , T-47D 细胞
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N6-methyladenosine-mediated downregulation of miR-374c-5p promotes cadmium-induced cell proliferation and metastasis by targeting GRM3 in breast cancer cells (2021-12-15)
期刊: ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI:10.1016/j.ecoenv.2021.113085
影响因子 :6.8
引用产品: T-47D 细胞 , MCF7 [MCF-7] 细胞
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CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer (2010-01-20)
期刊:Experimental And Molecular Pathology
DOI:10.1016/j.yexmp.2021.104704
影响因子 :4.4
引用产品: MCF 10A 细胞 , T-47D 细胞 , MCF7 [MCF-7] 细胞 , MDA-MB-231细胞专用培养基 (DMEM) , BT-549 细胞 , SK-BR-3 [SKBR3] 细胞
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Silence of α1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells (2009-08-20)
期刊:Medical Science Monitor
影响因子 :3.1
引用产品: ZR-75-30 细胞 , SK-BR-3 [SKBR3] 细胞 , T-47D 细胞 , MDA-MB-231 细胞
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