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产品概述
名称 | SK-MES-1 (人肺鳞癌细胞) (STR鉴定正确) |
别称 | SK MES 1; SKMES-1; SK-Mes-1; SK-MES1; SKMES1; SK-MES; SKMES |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
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推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | SK-MES-1细胞是由G·Trempe和L·J·Old于1970年从一个患肺部鳞癌的病人胸水中分离培养。 |
年龄(性别) | 男性;65岁 |
组织来源 | 肺鳞状细胞癌;转移位置:胸水 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肺癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~50 hours |
抗原表达情况 | Blood Type O; Rh+; HLA A3, Aw30, B7, B27 |
保藏机构 | ATCC; HTB-58 DSMZ; ACC-353 ECACC; 91091804ECACC; 93120837 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 12 D2S1338 19 D3S1358 16 D5S818 11 D7S820 8 D8S1179 13,14 D13S317 11 D16S539 13 D18S51 17 D19S433 14 D21S11 29,30 FGA 20,24 PentaD 12,13 PentaE 5,11 TH01 6,9.3 TPOX 8 vWA 14 D6S1043 12,19 D12S391 22 D2S441 10,14 -
STR鉴定图
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参考文献
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Tumor-suppressive miR-4732-3p is sorted into fucosylated exosome by hnRNPK to avoid the inhibition of lung cancer progression (2024-04-23)
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-024-03048-1
影响因子 :11.3
引用产品: NCI-H226 [H226] 细胞 , 293T [HEK-293T] 细胞 , BEAS-2B 细胞 , SK-MES-1 细胞 , A549 [A-549] 细胞 , 特级胎牛血清 , NCI-H460 [H460] 细胞 , NCI-H1299 细胞
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MiR-183-5p inhibits lung squamous cell carcinoma survival through disrupting hypoxia adaptation mediated by HIF-1α/NDUFA4L2 axis (2024-08-17)
期刊:ONCOGENE
DOI:10.1038/s41388-024-03129-7
影响因子 :6.9
引用产品: NCI-H226 [H226] 细胞 , SK-MES-1 细胞
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TFAP2C-mediated transcriptional activation of STEAP3 promotes lung squamous cell carcinoma progression by regulating the β-catenin pathway (2024-12-24)
期刊:Biology Direct
DOI:10.1186/s13062-024-00584-w
影响因子 :5.7
引用产品: NCI-H1703 细胞 , SK-MES-1 细胞 , NCI-H520 细胞 , NCI-H226 [H226] 细胞
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Liquiritigenin Induces Cell Cycle Arrest and Apoptosis in Lung Squamous Cell Carcinoma (2024-05-22)
期刊:CELL BIOCHEMISTRY AND BIOPHYSICS
DOI:10.1007/s12013-024-01294-w
影响因子 :2.6
引用产品: NCI-H520 细胞 , SK-MES-1 细胞
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IGF2BP3/CTCF Axis–Dependent NT5DC2 Promotes M2 Macrophage Polarization to Enhance the Malignant Progression of Lung Squamous Cell Carcinomas (2024-11-06)
期刊:Clinical Respiratory Journal
影响因子 :1.9
引用产品: DMEM高糖 培养基 , SK-MES-1 细胞 , BEAS-2B 细胞 , RPMI-1640 培养基
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Regulation of tumorigenesis and ferroptosis in non-small cell lung cancer by a novel BBOX1-AS1/miR-326/PROM2 axis (2023-08-28)
期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI:10.1007/s11010-023-04837-6
影响因子 :4.3
引用产品: BEAS-2B 细胞 , A549 [A-549] 细胞 , SK-MES-1 细胞 , NCI-H1299 细胞 , NCI-H520 细胞 , Ham's F-12K 培养基 , MEM (含NEAA) 培养基 , RPMI-1640 培养基 , DMEM高糖 培养基
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LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis (2023-09-05)
期刊:Cancer Biomarkers
影响因子 :3.1
引用产品: BEAS-2B 细胞 , NCI-H1703 细胞 , SK-MES-1 细胞 , NCI-H520 细胞
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The antihypertensive felodipine shows synergistic activity with immune checkpoint blockade and inhibits tumor growth via NFAT1 in LUSC (2023-09-22)
期刊:Open Medicine
影响因子 :2.1
引用产品: SK-MES-1 细胞 , NCI-H226 [H226] 细胞
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MiR-654-3p targets SRC to suppress tumor growth in non-small cell lung cancer (2023-04-30)
期刊:CELLULAR AND MOLECULAR BIOLOGY
影响因子 :1.6
引用产品: A549 [A-549] 细胞 , NCI-H1299 细胞 , SK-MES-1 细胞 , BEAS-2B 细胞
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Downregulation of T-cell cytotoxic marker IL18R1 promotes cancer proliferation and migration and is associated with dismal prognosis and immunity in lung squamous cell carcinoma (2022-12-05)
期刊:Frontiers in Immunology
影响因子 :8.8
引用产品: SK-MES-1 细胞
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M7G-Related lncRNAs predict prognosis and regulate the immune microenvironment in lung squamous cell carcinoma (2022-11-04)
期刊:BMC CANCER
DOI:10.1186/s12885-022-10232-z
影响因子 :4.6
引用产品: NCI-H226 [H226] 细胞 , SK-MES-1 细胞 , BEAS-2B 细胞
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DNMT3b-mediated SPAG6 promoter hypermethylation affects lung squamous cell carcinoma development through the JAK/STAT pathway (2022-10-15)
期刊:American Journal of Translational Research
DOI:PMID:36398260
影响因子 :3.9
引用产品: BEAS-2B 细胞 , SK-MES-1 细胞 , NCI-H1703 细胞
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Proteasome 26S subunit, non-ATPase 1 (PSMD1) facilitated the progression of lung adenocarcinoma by the de-ubiquitination and stability of PTEN-induced kinase 1 (PINK1) (2022-02-19)
期刊:Experimental Cell Research
DOI:10.1016/j.yexcr.2022.113075
影响因子 :3.7
引用产品: SK-MES-1 细胞 , NCI-H2170 细胞 , HCC827 细胞 , A549 [A-549] 细胞
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circRNA-mediated upregulation of HOXC9 is correlated with poor outcome and immune microenvironment infiltrates in LUAD (2022-10-14)
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2022.10.043
影响因子 :3.3
引用产品: A549 [A-549] 细胞 , SK-MES-1 细胞
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The Potential Mechanism of HDAC1-Catalyzed Histone Crotonylation of Caspase-1 in Nonsmall Cell Lung Cancer (2022-08-02)
期刊:Evidence-based Complementary and Alternative Medicine
影响因子 :2.7
引用产品: A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H460 [H460] 细胞 , SK-MES-1 细胞 , NCI-H226 [H226] 细胞 , NCI-H661 细胞 , BEAS-2B 细胞 , 16HBE 细胞
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Mir-556-3p Inhibits SqCLC via NUAK1 (2022-01-01)
期刊:International Journal of Surgery-Oncology
影响因子 :
引用产品: NCI-H226 [H226] 细胞 , SK-MES-1 细胞 , MEM 培养基
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Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway (2021-12-07)
期刊:Bioengineered
DOI:10.1080/21655979.2021.2005931
影响因子 :4.9
引用产品: BEAS-2B , SK-MES-1 细胞 , NCI-H520 细胞
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TFAP2A-induced SLC2A1-AS1 promotes cancer cell proliferation (2021-02-19)
期刊:Biological Chemistry
影响因子 :3.7
引用产品: SK-MES-1 细胞 , PANC-1 细胞
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CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway (2021-11-12)
期刊:Experimental Cell Research
DOI:10.1016/j.yexcr.2021.112914
影响因子 :3.7
引用产品: A549 [A-549] 细胞 , HCC827 细胞 , SK-MES-1 细胞
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Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275 (2020-12-31)
期刊:Bioengineered
DOI:10.1080/21655979.2020.1860492
影响因子 :4.9
引用产品: Ham's F-12K 培养基 , A549 [A-549] 细胞 , SK-MES-1 细胞 , NCI-H1437 细胞 , NCI-H1975 细胞
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