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产品概述
| 名称 | SK-MES-1 (人肺鳞癌细胞) (STR鉴定正确) |
| 别称 | SK MES 1; SKMES-1; SK-Mes-1; SK-MES1; SKMES1; SK-MES; SKMES |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
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| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | SK-MES-1细胞是由G·Trempe和L·J·Old于1970年从一个患肺部鳞癌的病人胸水中分离培养。 |
| 年龄（性别） | 男性；65岁 |
| 组织来源 | 肺鳞状细胞癌；转移位置：胸水 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~50 hours |
| 抗原表达情况 | Blood Type O; Rh+; HLA A3, Aw30, B7, B27 |
| 保藏机构 | ATCC; HTB-58 DSMZ; ACC-353 ECACC; 91091804ECACC; 93120837 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 12 D2S1338 19 D3S1358 16 D5S818 11 D7S820 8 D8S1179 13,14 D13S317 11 D16S539 13 D18S51 17 D19S433 14 D21S11 29,30 FGA 20,24 PentaD 12,13 PentaE 5,11 TH01 6,9.3 TPOX 8 vWA 14 D6S1043 12,19 D12S391 22 D2S441 10,14 -
STR鉴定图
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参考文献
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Regulation of tumorigenesis and ferroptosis in non-small cell lung cancer by a novel BBOX1-AS1/miR-326/PROM2 axis (2023-08-28)
作者：Jinlu An:1.Department of Geriatric Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China. ; Jiang Shi:1.Department of Geriatric Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China. shijiangdoc@163.com. ; Chao Yang:1.Department of Geriatric Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China. ; Junfang Luo:1.Department of Geriatric Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China. ; Yuning Li:1.Department of Geriatric Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China. ; Jie Ren:1.Department of Geriatric Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzh
期刊：Regulation of tumorigenesis and ferroptosis in non-small cell lung cancer by a novel BBOX1-AS1/miR-326/PROM2 axis
DOI：10.1007/s11010-023-04837-6
影响因子 ：4.3
引用产品： BEAS-2B 细胞 , A549 [A-549] 细胞 , SK-MES-1 细胞 , NCI-H1299 细胞 , NCI-H520 细胞 , Ham's F-12K 培养基 , MEM (含NEAA) 培养基 , RPMI-1640 培养基 , DMEM高糖 培养基
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LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis (2023-09-05)
作者：Zhibin Lu:1.The First Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu, China. ; 2.Nanjing Pukou People's Hospital, Nanjing, Jiangsu, China. ; 3.The First Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu, China. ; Zhichao Xiao:1.Nanjing Pukou People's Hospital, Nanjing, Jiangsu, China. ; 2.The First Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu, China. ; Qi Wang:1.The First Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu, China. ; 2.Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. ; 3.The First Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu, China. ; Chunfeng Pan:1.Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. ; Yang Xia:1.Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanji
期刊：LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis
影响因子 ：3.1
引用产品： BEAS-2B 细胞 , NCI-H1703 细胞 , SK-MES-1 细胞 , NCI-H520 细胞
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The antihypertensive felodipine shows synergistic activity with immune checkpoint blockade and inhibits tumor growth via NFAT1 in LUSC (2023-09-22)
作者：Si-Yu Liang:1.Department of Cardiology, The Fourth Affiliated Hospital of Guangzhou Medical University, Zengcheng, Guangzhou, China. ; Hong-Kai Xiao:1.Department of Cardiology, The Fourth Affiliated Hospital of Guangzhou Medical University, Zengcheng, Guangzhou, China. ;
期刊：The antihypertensive felodipine shows synergistic activity with immune checkpoint blockade and inhibits tumor growth via NFAT1 in LUSC
影响因子 ：2.1
引用产品： SK-MES-1 细胞 , NCI-H226 [H226] 细胞
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MiR-654-3p targets SRC to suppress tumor growth in non-small cell lung cancer (2023-04-30)
作者：Min Pang:1.Department of Respiratory and Critical Care Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan637000, China. xx283742817@163.com. ; Yongjie Jiang:1.Department of Respiratory and Critical Care Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan637000, China. 7851256@qq.com. ; Yuyan Huang:1.Department of Respiratory and Critical Care Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan637000, China. 78033295@qq.com. ; Bi Ren:1.Department of Respiratory and Critical Care Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan637000, China. 834463615@qq.com. ; Liping He:1.Department of Respiratory and Critical Care Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan637000, China. 1053577321@qq.com. ; Li Jiang:1.Department of Respiratory and Critical Care Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sic
期刊：MiR-654-3p targets SRC to suppress tumor growth in non-small cell lung cancer
影响因子 ：1.6
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , SK-MES-1 细胞 , BEAS-2B 细胞
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M7G-Related lncRNAs predict prognosis and regulate the immune microenvironment in lung squamous cell carcinoma (2022-11-04)
作者：Junfan Pan:1.Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, China. ; Zhidong Huang:1.The Second Surgical Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, 300060, China. ; Hancui Lin:1.Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, China. ; Wenfang Cheng:1.Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, China. ; Jinhuo Lai:1.Department of Medical Oncology, Fujian Medical University Union Hospital, Fuzhou, 350001, China. 571747377@qq.com. ; Jiancheng Li:1.Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, China. jianchengli_jack@126.com. ;
期刊：M7G-Related lncRNAs predict prognosis and regulate the immune microenvironment in lung squamous cell carcinoma
DOI：10.1186/s12885-022-10232-z
影响因子 ：4.6
引用产品： NCI-H226 [H226] 细胞 , SK-MES-1 细胞 , BEAS-2B 细胞
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Proteasome 26S subunit, non-ATPase 1 (PSMD1) facilitated the progression of lung adenocarcinoma by the de-ubiquitination and stability of PTEN-induced kinase 1 (PINK1) (2002-02-20)
作者：Lihua Liu:1.School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China. Electronic address: liulihuajz@163.com. ; Aihua Liu:1.Department of General Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China. Electronic address: lewaiwa919@163.com. ; Jun Dong:1.Medical Education Research Center, Jinzhou Medical University, Jinzhou, Liaoning, China. Electronic address: 105022998@qq.com. ; Zhongfu Zuo:1.School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China. Electronic address: Zuozhongfu11@126.com. ; Xuezheng Liu:1.School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China. Electronic address: lxz_jzykdx@163.com. ;
期刊：Proteasome 26S subunit, non-ATPase 1 (PSMD1) facilitated the progression of lung adenocarcinoma by the de-ubiquitination and stability of PTEN-induced kinase 1 (PINK1)
DOI：10.1016/j.yexcr.2022.113075
影响因子 ：3.7
引用产品： SK-MES-1 细胞 , NCI-H2170 细胞 , HCC827 细胞 , A549 [A-549] 细胞
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circRNA-mediated upregulation of HOXC9 is correlated with poor outcome and immune microenvironment infiltrates in LUAD (2022-10-14)
作者：Yunlong Liu:1.Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Baoshan Branch, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China. ; Liling Jing:1.Changhai Hospital, The Second Military Medical University, Shanghai, China. ; Jie Zhang:1.Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address: zhangjie6218@163.com. ;
期刊：circRNA-mediated upregulation of HOXC9 is correlated with poor outcome and immune microenvironment infiltrates in LUAD
DOI：10.1016/j.bbrc.2022.10.043
影响因子 ：3.3
引用产品： A549 [A-549] 细胞 , SK-MES-1 细胞
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The Potential Mechanism of HDAC1-Catalyzed Histone Crotonylation of Caspase-1 in Nonsmall Cell Lung Cancer (2022-08-02)
作者：Chuan Jiang:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Jiangrong Liao:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Fang Yang:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Ting Jiang:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Dan Zhang:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Yuanjun Xin:1.The Third Affiliated Hospital of Zunyi Medical University, Zunyi, China. ;
期刊：The Potential Mechanism of HDAC1-Catalyzed Histone Crotonylation of Caspase-1 in Nonsmall Cell Lung Cancer
影响因子 ：2.7
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H460 [H460] 细胞 , SK-MES-1 细胞 , NCI-H226 [H226] 细胞 , NCI-H661 细胞 , BEAS-2B 细胞 , 16HBE 细胞
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Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway (2012-01-20)
作者：Zhonghai Xie:1.Department of Thoracic Surgery, Huzhou Central Hospital, Huzhou, Zhejiang Province, China. ; Hongwei Li:1.Department of Thoracic Surgery, Huzhou Central Hospital, Huzhou, Zhejiang Province, China. ; Jin Zang:1.Department of Thoracic Surgery, Huzhou Central Hospital, Huzhou, Zhejiang Province, China. ;
期刊：Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway
DOI：10.1080/21655979.2021.2005931
影响因子 ：4.9
引用产品： BEAS-2B , SK-MES-1 细胞 , NCI-H520 细胞
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TFAP2A-induced SLC2A1-AS1 promotes cancer cell proliferation (2002-01-20)
作者：Yuanbo Cui:1.School of Life Sciences, Zhengzhou University, Zhengzhou450001, China. ; Chunyan Zhang:1.Department of Clinical Laboratory, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou450007, China. ; Shanshan Ma:1.School of Life Sciences, Zhengzhou University, Zhengzhou450001, China. ; Fangxia Guan:1.School of Life Sciences, Zhengzhou University, Zhengzhou450001, China. ;
期刊：TFAP2A-induced SLC2A1-AS1 promotes cancer cell proliferation
影响因子 ：3.7
引用产品： SK-MES-1 细胞 , PANC-1 细胞
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CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway (2011-01-20)
作者：Decai Chi:1.Department of General Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin, 150086, China. ; Dong Wang:1.Department of Respiratory Medicine, Second Affiliated Hospital of Harbin Medical University, Harbin, 150086, China. ; Minghui Zhang:1.Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, 150081, China. ; Hui Ma:1.Harbin Medical University, Harbin, 150086, China. ; Fuhui Chen:1.Department of Respiratory Medicine, Second Affiliated Hospital of Harbin Medical University, Harbin, 150086, China. Electronic address: chenfuhui2019@163.com. ; Yajiao Sun:1.Department of Respiratory Medicine, Second Affiliated Hospital of Harbin Medical University, Harbin, 150086, China. Electronic address: sunyajiao2019@163.com. ;
期刊：CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway
DOI：10.1016/j.yexcr.2021.112914
影响因子 ：3.7
引用产品： A549 [A-549] 细胞 , HCC827 细胞 , SK-MES-1 细胞
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Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275 (2012-00-20)
作者：Junpeng Feng:1.Department of Thoracic Surgery, The Fourth Hospital of Hebei Medical University , Shijiazhuang, P.R. China. ; 2.Department of Thoracic Surgery, Hebei Chest Hospital , Shijiazhuang, P.R. China. ; Jianhang Li:1.Department of Thoracic Surgery, Hebei Chest Hospital , Shijiazhuang, P.R. China. ; Peng Qie:1.Department of Thoracic Surgery, Hebei General Hospital , Shijiazhuang, P.R. China. ; Zhenhua Li:1.Department of Thoracic Surgery, The Fourth Hospital of Hebei Medical University , Shijiazhuang, P.R. China. ; Yanzhao Xu:1.Department of Thoracic Surgery, The Fourth Hospital of Hebei Medical University , Shijiazhuang, P.R. China. ; Ziqiang Tian:1.Department of Thoracic Surgery, The Fourth Hospital of Hebei Medical University , Shijiazhuang, P.R. China. ;
期刊：Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275
DOI：10.1080/21655979.2020.1860492
影响因子 ：4.9
引用产品： Ham's F-12K 培养基 , A549 [A-549] 细胞 , SK-MES-1 细胞 , NCI-H1437 细胞 , NCI-H1975 细胞
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