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产品概述
| 名称 | NCI-H1975 (人肺腺癌细胞) (STR鉴定正确) |
| 别称 | H1975; H-1975 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:6 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 细胞正常生长过程中存在较多漂浮，背景存在黑点，正常培养即可，无需频繁换液处理。 |
| 背景描述 | NCI-H1975细胞是于1988年7月从一名女性(无抽烟史)非小细胞肺腺癌组织中分离得到的。 |
| 年龄（性别） | 女性 |
| 组织来源 | 器官：肺；疾病：腺癌；非小细胞肺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~28-45 hours |
| 保藏机构 | ATCC; CRL-5908 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 17 D3S1358 14,15 D5S818 11,12 D7S820 8,11 D8S1179 13,16 D13S317 10,13 D16S539 9,12 D18S51 13 D19S433 15,15.2 D21S11 28 FGA 21,24 PentaD 12,13 PentaE 12,16 TH01 7 TPOX 8,11 vWA 18 D6S1043 12 D12S391 17 D2S441 10,11 -
STR鉴定图
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参考文献
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Chemically engineered antibodies for autophagy-based receptor degradation (2025-01-09)
期刊：Nature Chemical Biology
DOI：10.1038/s41589-024-01803-1
影响因子 ：12.9
引用产品： Hela 细胞 , MDA-MB-231 细胞 , U-87 MG 细胞 , A549 [A-549] 细胞 , PANC-1 细胞 , NCI-H292 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞 , A-375 细胞 , HuH-7 细胞 , 293T [HEK-293T] 细胞
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HVEM as a Tumor-Intrinsic Regulator in Non-Small Cell Lung Cancer: Suppression of Metastasis via Glycolysis Inhibition and Modulation of Macrophage Polarization (2025-01-18)
期刊：PHARMACOLOGICAL RESEARCH
DOI：10.1016/j.phrs.2025.107604
影响因子 ：9.1
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H1299 细胞 , NCI-H226 [H226] 细胞 , PC-9 细胞 , NCI-H520 细胞 , NCI-H1563 细胞 , BEAS-2B 细胞 , THP-1 细胞
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Discovery of novel dual-target inhibitors of LSD1/EGFR for non-small cell lung cancer therapy (2025-01-03)
期刊：ACTA PHARMACOLOGICA SINICA
DOI：10.1038/s41401-024-01439-w
影响因子 ：6.9
引用产品： NCI-H460 [H460] 细胞 , NCI-H1299 细胞 , PC-9 细胞 , NCI-H1975 细胞
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Super-Resolution Fluorescence Imaging Reveals the Mechanism of NRP1 Clustering on Non-Small-Cell Lung Cancer Membranes (2025-01-22)
期刊：ANALYTICAL CHEMISTRY
DOI：10.1021/acs.analchem.4c05675
影响因子 ：6.7
引用产品： NCI-H1650 细胞 , NCI-H1975 细胞 , HCC827 细胞
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Estrogen sulfotransferase SULT1E1 expression correlates with progression and prognosis of lung adenocarcinoma (2025-01-06)
期刊：Scientific Reports
DOI：10.1038/s41598-024-82129-9
影响因子 ：3.8
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H1734 细胞 , NCI-H838 细胞 , HCC827 细胞 , BEAS-2B 细胞 , NCI-H1975 细胞
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High-throughput and proteome-wide discovery of endogenous biomolecular condensates (2024-03-18)
期刊：Nature Chemistry
DOI：10.1038/s41557-024-01485-1
影响因子 ：21.8
引用产品： NCI-H1975 细胞 , NIH/3T3 细胞
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Noninvasive Immunotyping and Immunotherapy Monitoring of Lung Cancers via Nuclear Imaging of LAG-3 and PD-L1 (2024-11-08)
期刊：Advanced Science
影响因子 ：14.3
引用产品： NCI-H1975 细胞
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S1PR1 suppresses lung adenocarcinoma progression through p-STAT1/miR-30c-5 p/FOXA1 pathway (2024-11-18)
期刊：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI：10.1186/s13046-024-03230-5
影响因子 ：11.4
引用产品： DMEM高糖 培养基 , 293T [HEK-293T] 细胞 , BEAS-2B 细胞 , NCI-H838 细胞 , 特级胎牛血清 , A549 [A-549] 细胞 , RPMI-1640 培养基 , NCI-H1975 细胞
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N6-methyladenosine-modified SRPK1 promotes aerobic glycolysis of lung adenocarcinoma via PKM splicing (2024-08-02)
期刊：CELLULAR & MOLECULAR BIOLOGY LETTERS
DOI：10.1186/s11658-024-00622-5
影响因子 ：9.2
引用产品： BEAS-2B 细胞 , NCI-H226 [H226] 细胞 , HCC827 细胞 , NCI-H1299 细胞 , RPMI-1640 培养基 , A549 [A-549] 细胞 , PC-9 细胞 , DMEM高糖 培养基 , 293T [HEK-293T] 细胞 , NCI-H1650 细胞 , NCI-H1975 细胞
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PIM1 kinase promotes EMT-associated osimertinib resistance via regulating GSK3β signaling pathway in EGFR-mutant non-small cell lung cancer (2024-09-03)
期刊：Cell Death & Disease
DOI：10.1038/s41419-024-07039-0
影响因子 ：8.1
引用产品： NCI-H1975 细胞 , PC-9 细胞
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Targeting TYK2 alleviates Rab27A-induced malignant progression of non-small cell lung cancer via disrupting IFNα-TYK2-STAT-HSPA5 axis (2024-03-23)
期刊：npj Precision Oncology
DOI：10.1038/s41698-024-00574-1
影响因子 ：7.9
引用产品： 293T [HEK-293T] 细胞 , BEAS-2B 细胞 , NCI-H1299 细胞 , A549 [A-549] 细胞 , LTEP-α-2 细胞 , NCI-H226 [H226] 细胞 , Calu-3 细胞 , HCC827 细胞 , NCI-H1975 细胞
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Bioinformatics and experimental approach identify lipocalin 2 as a diagnostic and prognostic indicator for lung adenocarcinoma (2024-06-06)
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2024.132797
影响因子 ：7.7
引用产品： PC-9 细胞 , NCI-H1975 细胞 , BEAS-2B 细胞
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Spinosad blocks CHRNA5 mediated EGFR signaling pathway activation to inhibit lung adenocarcinoma proliferation (2024-07-14)
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.117105
影响因子 ：6.9
引用产品： RPMI-1640 培养基 , A549 [A-549] 细胞 , NCI-H1975 细胞 , PC-9 细胞
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Novel PD-L1/VISTA Dual Inhibitor as Potential Immunotherapy Agents (2024-12-28)
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.4c01640
影响因子 ：6.8
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , SK-OV-3 细胞
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Activation of Hypoxia Inducible Factor-1 Alpha-Mediated DNA Methylation Enzymes (DNMT3a and TET2) Under Hypoxic Conditions Regulates S100A6 Transcription to Promote Lung Cancer Cell Growth and Metastasis (2024-03-18)
期刊：ANTIOXIDANTS & REDOX SIGNALING
影响因子 ：6.6
引用产品： BEAS-2B 细胞 , Calu-3 细胞 , NCI-H1395 细胞 , NCI-H1975 细胞 , A549 [A-549] 细胞
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IGSF9 promotes tumor invasion and metastasis through GSK-3β/β-catenin mediated EMT in lung cancer (2024-10-08)
期刊：NEOPLASIA
影响因子 ：6.3
引用产品： NCI-H1975 细胞
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Design, synthesis and antitumor activity of a novel FGFR2-selective degrader to overcome resistance of the FGFR2V564F gatekeeper mutation based on a pan-FGFR inhibitor (2024-06-18)
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2024.116612
影响因子 ：6.0
引用产品： KATO III [KATO 3] 细胞 , AN3 CA 细胞 , A2780 细胞 , BxPC-3 细胞 , MCF7 [MCF-7] 细胞 , HuH-7 细胞 , MDA-MB-231 细胞 , HCT 116 细胞 , 22RV1 细胞 , HL-7702 [L-02; LO2] 细胞 , 293 [HEK-293] 细胞 , 293T [HEK-293T] 细胞 , NCI-H1975 细胞
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SLCO4A1, as a novel prognostic biomarker of non?small cell lung cancer, promotes cell proliferation and migration (2024-01-23)
期刊：INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子 ：5.2
引用产品： NCI-H157 细胞 , NCI-H1975 细胞 , NCI-H1299 细胞 , A549 [A-549] 细胞 , BEAS-2B 细胞
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MiR-3074-5p suppresses non-small cell lung cancer progression by targeting the YWHAZ/Hsp27 axis (2024-06-28)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112547
影响因子 ：4.8
引用产品： BEAS-2B 细胞 , Ham's F-12K 培养基 , A549/Tax 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , BEAS-2B细胞专用培养基
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CALU promotes lung adenocarcinoma progression by enhancing cell proliferation, migration and invasion (2024-07-05)
期刊：RESPIRATORY RESEARCH
DOI：10.1186/s12931-024-02901-3
影响因子 ：4.7
引用产品： NCI-H1299 细胞 , HCC827 细胞 , PC-9 细胞 , 95-D [PLA-801D] 细胞 , A549 [A-549] 细胞 , Hela 299 细胞 , NCI-H1975 细胞
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Shenqifuzheng injection inhibits lactic acid-induced cisplatin resistance in NSCLC by affecting FBXO22/p53 axis through FOXO3 (2024-11-01)
期刊：RESPIRATORY RESEARCH
DOI：10.1186/s12931-024-03013-8
影响因子 ：4.7
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞
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Cytotoxic diterpenoids from Croton kongensis inhibiting tumor proliferation and migration (2024-08-22)
期刊：BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2024.107739
影响因子 ：4.5
引用产品： MDA-MB-231 细胞 , MCF7 [MCF-7] 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , Hela 细胞
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HNRNPD/MAD2L2 axis facilitates lung adenocarcinoma progression and is a potential prognostic biomarker (2024-10-02)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2024.111443
影响因子 ：4.4
引用产品： Calu-3 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , PC-9 细胞 , 人脐静脉内皮细胞
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Epigenetic Regulation of RNF135 by LSD1 Promotes Stemness Maintenance and Brain Metastasis in Lung?Adenocarcinoma (2024-08-31)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.4
引用产品： Ham's F-12K 培养基 , A549 [A-549] 细胞 , RPMI-1640 培养基 , NCI-H1975 细胞
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Synergistic antitumor activity of baicalein combined with almonertinib in almonertinib-resistant non-small cell lung cancer cells through the reactive oxygen species-mediated PI3K/Akt pathway (2024-07-31)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2024.1405521
影响因子 ：4.4
引用产品： NCI-H1975 细胞 , HCC827 细胞
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LINC00941 is a diagnostic biomarker for lung adenocarcinoma and promotes tumorigenesis through cell autophagy (2024-10-11)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：4.3
引用产品： NCI-H1299 细胞 , NCI-H1975 细胞 , Ham's F-12K 培养基 , HCC827 细胞 , A549 [A-549] 细胞
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Experimental study on the inhibitory effect of Halofuginone on NSCLC (2024-12-20)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2024.177221
影响因子 ：4.2
引用产品： HCC827 细胞 , NCI-H1975 细胞
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Integrated analysis of purine metabolism assists in predicting prognosis and treatment decisions for patients with lung adenocarcinoma (2024-04-04)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e29290
影响因子 ：4.0
引用产品： NCI-H1975 细胞 , A549 [A-549] 细胞
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Construction of shared gene signature between rheumatoid arthritis and lung adenocarcinoma helps to predict the prognosis and tumor microenvironment of the LUAD patients (2024-01-10)
期刊：Frontiers in Molecular Biosciences
DOI：10.3389/fmolb.2023.1314753
影响因子 ：3.9
引用产品： BEAS-2B 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , PC-9 细胞
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Cytochalasin H enhances sensitivity to gefitinib in non-small-cell lung cancer cells through inhibiting EGFR activation and PD-L1 expression (2024-10-25)
期刊：Scientific Reports
DOI：10.1038/s41598-024-76060-2
影响因子 ：3.8
引用产品： NCI-H1975 细胞 , HCC827 细胞
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Silencing of circ_0088036 inhibits growth and invasion of lung adenocarcinoma through miR-203/SP1 axis (2024-03-27)
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 ：3.6
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , PC-9 细胞 , NCI-H1975 细胞 , BEAS-2B 细胞
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Highly consistency of PIK3CA mutation spectrum between circulating tumor DNA and paired tissue in lung cancer patients (2024-07-04)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e34013
影响因子 ：3.4
引用产品： NCI-H358 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H2228 [H2228; H-2228] 细胞 , H3255 细胞 , 特级胎牛血清 , DMEM高糖 培养基
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SIRT5 participates in the suppressive tumor immune microenvironment of EGFR-mutant LUAD by regulating the succinylation of ACAT1 (2024-10-22)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e39743
影响因子 ：3.4
引用产品： PC-9 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , Calu-1 细胞
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Auriculasin induces mitochondrial oxidative stress and drives ferroptosis by inhibiting PI3K/Akt pathway in non-small?cell?lung?cancer (2024-08-02)
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-024-03328-9
影响因子 ：3.1
引用产品： Calu-1 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H226 [H226] 细胞 , BEAS-2B 细胞
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Knockdown of HM13 Inhibits Metastasis, Proliferation, and M2 Macrophage Polarization of Non-small Cell Lung Cancer Cells by Suppressing the JAK2/STAT3 Signaling Pathway (2024-08-29)
期刊：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
DOI：10.1007/s12010-024-05054-7
影响因子 ：3.1
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H1299 细胞 , Calu-3 细胞
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Circular RNA circ_001621 acts as a tumor promoter in lung cancer by regulating the miR-199a-3p/GREM1 axis (2024-06-28)
期刊：Archives of Medical Science
影响因子 ：3.0
引用产品： Calu-3 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , PC-9 细胞 , BEAS-2B 细胞 , RPMI-1640 培养基 , MEM 培养基 , Ham's F-12K 培养基 , DMEM高糖 培养基 , 特级胎牛血清
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KIF2C as a potential therapeutic target: insights from lung adenocarcinoma subtype classification and functional experiments (2024-06-18)
期刊：Molecular Omics
影响因子 ：3.0
引用产品： NCI-H1975 细胞 , 293 [HEK-293] 细胞
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Unlocking the Potential of Disulfidptosis-Related LncRNAs in Lung Adenocarcinoma: A Promising Prognostic LncRNA Model for Survival and Immunotherapy Prediction (2024-10-21)
期刊：Cancer Medicine
影响因子 ：2.9
引用产品： NCI-H1299 细胞 , BEAS-2B 细胞 , NCI-H460 [H460] 细胞 , NCI-H1975 细胞
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Poor therapeutic outcomes in KRAS-mutant non-small cell lung cancer due to chemoresistance conferred by SLC7A11 (2024-07-26)
期刊：Clinical & Translational Oncology
DOI：10.1007/s12094-024-03592-4
影响因子 ：2.8
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H23 细胞 , NCI-H1299 细胞
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Depletion of NUAK2 blocks the stemness and angiogenesis and facilitates senescence of lung adenocarcinoma cells via enhancing ferroptosis (2024-07-28)
期刊：Cell Division
DOI：10.1186/s13008-024-00128-8
影响因子 ：2.8
引用产品： PC-9 细胞 , HCC827 细胞 , NCI-H1975 细胞 , A549 [A-549] 细胞
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PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway (2024-01-19)
期刊：Genes & Genomics
DOI：10.1007/s13258-023-01484-5
影响因子 ：2.1
引用产品： BEAS-2B 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H1299 细胞 , Calu-1 细胞
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STIL enhances the development of lung adenocarcinoma by regulating the glycolysis pathway (2024-12-20)
期刊：ONCOLOGY RESEARCH
影响因子 ：2.0
引用产品： 16HBE 细胞 , NCI-H1975 细胞 , NCI-H1299 细胞 , NCI-H23 细胞 , A549 [A-549] 细胞
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The Deubiquitinase USP22-Stabilized COL17A1 Promotes Lung Adenocarcinoma Progression (2024-08-14)
期刊：Clinical Respiratory Journal
影响因子 ：1.9
引用产品： NCI-H1975 细胞 , A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H23 细胞
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Sinensetin Inhibits Angiogenesis in Lung Adenocarcinoma via the miR-374c-5p/VEGF-A/VEGFR-2/AKT Axis (2024-07-20)
期刊：CELL BIOCHEMISTRY AND BIOPHYSICS
DOI：10.1007/s12013-024-01352-3
影响因子 ：1.8
引用产品： BEAS-2B 细胞 , A549 [A-549] 细胞 , 人脐静脉内皮细胞 , NCI-H1975 细胞
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Extracellular vesicles derived from stored red blood cell suspensions enhance invasion and migration of lung cancer cells by miR1246 and miR150-3p (2024-06-05)
期刊：VOX SANGUINIS
影响因子 ：1.8
引用产品： NCI-H1975 细胞
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MiR-3195?inhibits non-small cell lung cancer malignant behaviors along with cisplatin resistance through targeting?PFKFB4 (2024-07-28)
期刊：CELLULAR AND MOLECULAR BIOLOGY
影响因子 ：1.5
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , HCC827 细胞 , BEAS-2B 细胞 , NCI-H1299 细胞
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Highly Multiplexed, Efficient, and Automated Single-Cell MicroRNA Sequencing with Digital Microfluidics. (2023-11-28)
期刊：Small Methods
影响因子 ：12.4
引用产品： NCI-H1975 细胞 , A549 [A-549] 细胞 , NCI-H2228 [H2228; H-2228] 细胞
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Multivalent DNA Flowers for High-Performance Isolation, Detection, and Release of Tumor-Derived Extracellular Vesicles (2023-11-26)
期刊：ACS Applied Materials & Interfaces
影响因子 ：9.5
引用产品： MCF7 [MCF-7] 细胞 , A-375 细胞 , MCF 10A 细胞 , NCI-H1975 细胞 , A549 [A-549] 细胞
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Dual Stimuli-Responsive Micelles for Imaging-Guided Mitochondrion-Targeted Photothermal/Photodynamic/Chemo Combination Therapy-Induced Immunogenic Cell Death (2023-08-01)
期刊：International Journal of Nanomedicine
影响因子 ：8.0
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , LLC [LL/2; LLC1] 细胞
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Design, Synthesis, and Biological Evaluation of Proteolysis-Targeting Chimeras as Highly Selective and Efficient Degraders of Extracellular Signal-Regulated Kinase 5 (2023-09-26)
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c00864
影响因子 ：7.3
引用产品： A-375 细胞 , HCT 116 细胞 , Hep G2 细胞 , MDA-MB-231 细胞 , NCI-H1975 细胞 , PC-3 细胞 , THP-1 细胞
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Anticancer effect of covalent purine-containing EGFR TKI, ZZC4 and its mechanism of action through network pharmacology (2023-11-27)
期刊：LIFE SCIENCES
影响因子 ：6.1
引用产品： HCC827 细胞 , NCI-H1975 细胞
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LncRNA CYP4A22-AS1 promotes the progression of lung adenocarcinoma through the miR-205-5p/EREG and miR-34c-5p/BCL-2 axes (2023-09-05)
期刊：Cancer Cell International
DOI：10.1186/s12935-023-03036-z
影响因子 ：5.8
引用产品： NCI-H1975 细胞 , 293T [HEK-293T] 细胞
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Structurally Diverse Diterpenes from the South China Sea Soft Coral Sarcophyton trocheliophorum (2023-01-20)
期刊：Marine Drugs
影响因子 ：5.4
引用产品： NCI-H1975 细胞 , MDA-MB-231 细胞 , A549 [A-549] 细胞 , NCI-H1299 细胞
-
Reduction in gefitinib resistance mediated by Yi-Fei San-Jie pill in non-small cell lung cancer through regulation of tyrosine metabolism, cell cycle, and the MET/EGFR signaling pathway (2023-05-09)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.4
引用产品： NCI-H1975 细胞
-
GPR37-centered ceRNA network contributes to metastatic potential in lung adenocarcinoma: Evidence from high-throughput sequencing (2023-11-16)
期刊：Translational Oncology
DOI：10.1016/j.tranon.2023.101819
影响因子 ：5.0
引用产品： A549 [A-549] 细胞 , NCI-H1395 细胞 , NCI-H1975 细胞 , Calu-3 细胞
-
lncRNA CERS6-AS1 upregulates the expression of ANLN by sponging miR-424-5p to promote the progression and drug resistance of lung adenocarcinoma (2023-12-01)
期刊：Non-coding RNA Research
DOI：10.1016/j.ncrna.2023.11.013
影响因子 ：5.0
引用产品： NCI-H1975 细胞 , NCI-H1299 细胞
-
GRIN2D knockdown suppresses the progression of lung adenocarcinoma by regulating the E2F signalling pathway (2023-04-19)
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2023.110685
影响因子 ：4.8
引用产品： NCI-H1299 细胞 , A549 [A-549] 细胞 , NCI-H23 细胞 , NCI-H1975 细胞
-
Comprehensive analysis of cuproptosis and copper homeostasis genotyping and related immune land scape in lung adenocarcinoma (2023-10-02)
期刊：Scientific Reports
DOI：10.1038/s41598-023-43795-3
影响因子 ：4.6
引用产品： PC-9 细胞 , NCI-H1975 细胞 , 16HBE 细胞 , 特级胎牛血清
-
Identification of ALG3 as a potential prognostic biomarker in lung adenocarcinoma (2023-07-08)
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e18065
影响因子 ：4.0
引用产品： NCI-H1975 细胞 , A549 [A-549] 细胞
-
Lactate dehydrogenase D serves as a novel biomarker for prognosis and immune infiltration in lung adenocarcinoma (2023-08-16)
期刊：BMC CANCER
DOI：10.1186/s12885-023-11221-6
影响因子 ：3.8
引用产品： NCI-H1299 细胞 , A549 [A-549] 细胞 , NCI-H838 细胞 , NCI-H1975 细胞
-
Mechanism of hypoxia-induced exosome circ_0051799 regulating the progression of lung adenocarcinoma (2023-05-11)
期刊：BIOLOGICAL CHEMISTRY
影响因子 ：3.7
引用产品： THP-1 细胞 , BEAS-2B 细胞 , A549 [A-549] 细胞 , PC-9 细胞 , NCI-H1975 细胞 , NCI-H1395 细胞
-
Multi-omics analysis of expression profile and prognostic values of connexin family in LUAD (2023-07-17)
期刊：JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI：10.1007/s00432-023-05075-5
影响因子 ：3.6
引用产品： NCI-H1975 细胞 , HCC827 细胞 , A549 [A-549] 细胞 , PC-9 细胞 , BEAS-2B 细胞
-
Circ_0006324 regulates cell proliferation, cell-cycle progression, apoptosis, and glycolysis of non-small cell lung cancer cells through miR-496/TRIM59 axis (2023-08-07)
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 ：3.6
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H522[H522] 细胞 , HCC827 细胞 , BEAS-2B 细胞
-
Intelligent Genetic Decoding System Based on Nucleic Acid Isothermal Amplification for Non-Small Cell Lung Cancer Diagnosis (2023-03-12)
期刊：Micromachines
影响因子 ：3.4
引用产品： NCI-H1975 细胞 , A549 [A-549] 细胞
-
Hydrogen Peroxide-Inducible PROTACs for Targeted Protein Degradation in Cancer Cells (2023-07-18)
期刊：CHEMBIOCHEM
影响因子 ：3.2
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞 , NCI-H520 细胞 , WI-38 细胞 , HULEC-5a 细胞
-
RNF182 induces p65 ubiquitination to affect PDL1 transcription and suppress immune evasion in lung adenocarcinoma (2023-05-22)
期刊：Immunity Inflammation and Disease
DOI：10.1002/iid3.864
影响因子 ：3.2
引用产品： BEAS-2B 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , 293T [HEK-293T] 细胞
-
IGF2BP1 enhances the stability of SIK2 mRNA through m6A modification to promote non-small cell lung cancer progression (2023-10-12)
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2023.10.045
影响因子 ：3.1
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , HCC827 细胞 , NCI-H1975 细胞 , 人支气管上皮细胞
-
Mechanisms analysis for Formononetin counteracted-Osimertinib resistance in non-small cell lung cancer cells: From the insight into the gene transcriptional level (2023-12-28)
期刊：Chemical Biology & Drug Design
影响因子 ：3.0
引用产品： NCI-H1975 细胞
-
Two New Cembranoids from the Chinese Soft Coral Sarcophyton boettgeri** (2023-05-31)
期刊：CHEMISTRY & BIODIVERSITY
影响因子 ：2.9
引用产品： NCI-H1975 细胞 , MDA-MB-231 细胞 , A549 [A-549] 细胞 , NCI-H1299 细胞
-
ERCC6 plays a promoting role in the progression of non-small cell lung cancer (2023-02-21)
期刊：Biochemistry and Cell Biology
影响因子 ：2.9
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞
-
Antitumor Cembrane Diterpenoids from the South China Sea Soft Coral Lobophytum sp. (2023-02-28)
期刊：CHEMISTRY & BIODIVERSITY
影响因子 ：2.9
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , MDA-MB-231 细胞 , NCI-H1299 细胞
-
MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34 (2023-06-13)
期刊：Oncology Letters
影响因子 ：2.9
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞
-
Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma (2023-02-24)
期刊：Thoracic Cancer
影响因子 ：2.9
引用产品： MRC-5 细胞 , MRC-5细胞专用培养基 , NCI-H1299 细胞 , NCI-H1975 细胞 , A549 [A-549] 细胞 , NCI-H1650 细胞 , PC-9 细胞
-
Tumor-related exosomal circ_0001715 promotes lung adenocarcinoma cell proliferation and metastasis via enhancing M2 macrophage polarization by regulating triggering receptor expressed on myeloid cells-2 (2023-12-12)
期刊：Thoracic Cancer
影响因子 ：2.9
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , BEAS-2B 细胞 , THP-1 细胞 , 293T [HEK-293T] 细胞
-
Upregulation of NDUFAF2 in Lung Adenocarcinoma Is a Novel Independent Prognostic Biomarker (2023-01-17)
期刊：Computational and Mathematical Methods in Medicine
影响因子 ：2.8
引用产品： PC-9 细胞 , NCI-H358 细胞 , A549 [A-549] 细胞 , HCC827 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞 , BEAS-2B 细胞
-
Silencing of Perilipin 3 Inhibits Lung Adenocarcinoma Cell Immune Resistance by Regulating the Transcription of PD-L1 Through c-Myc (2023-08-14)
期刊：IMMUNOLOGICAL INVESTIGATIONS
DOI：10.1080/08820139.2023.2244976
影响因子 ：2.8
引用产品： BEAS-2B 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H1299 细胞 , 青霉素-链霉素溶液 (双抗)，100× , Ham's F-12K 培养基
-
LncRNA PCAT6 promotes proliferation, migration, invasion, and epithelial-mesenchymal transition of lung adenocarcinoma cell by targeting miR-545-3p (2023-02-14)
期刊：MOLECULAR BIOLOGY REPORTS
DOI：10.1007/s11033-023-08259-x
影响因子 ：2.8
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , BEAS-2B 细胞
-
Dysregulated expression of microRNA involved in resistance to osimertinib in EGFR mutant non-small cell lung cancer cells (2023-04-24)
期刊：Journal of Thoracic Disease
影响因子 ：2.5
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞
-
CircSFMBT2 Plays an Oncogenic Role in Lung Adenocarcinoma Depending on the miR-1305/SALL4 Axis (2023-12-21)
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-023-10611-6
影响因子 ：2.4
引用产品： BEAS-2B 细胞 , NCI-H1975 细胞 , HCC827 细胞 , A549 [A-549] 细胞 , RPMI-1640 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100×
-
Circular circRANGAP1 Contributes to Non-small Cell Lung Cancer Progression by Increasing COL11A1 Expression Through Sponging miR-653-5p (2023-05-16)
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-023-10393-x
影响因子 ：2.4
引用产品： NCI-H23 细胞 , A549 [A-549] 细胞 , NCI-H1975 细胞 , BEAS-2B 细胞 , NCI-H23细胞专用培养基 , A549 [A-549]细胞专用培养基 , NCI-H1975细胞专用培养基 , BEAS-2B细胞专用培养基
-
Hsa_circ_0080608 Attenuates Lung Cancer Progression by Functioning as a Competitive Endogenous RNA to Regulate the miR-661/ADRA1A Pathway (2023-10-11)
期刊：HORMONE AND METABOLIC RESEARCH
影响因子 ：2.2
引用产品： A549 [A-549] 细胞 , Calu-3 细胞 , NCI-H1975 细胞 , PC-9 细胞 , BEAS-2B 细胞 , RPMI-1640 培养基 , 特级胎牛血清 , DMEM高糖 培养基
-
USP5-Beclin 1 axis overrides p53-dependent senescence and drives Kras-induced tumorigenicity (2022-12-17)
期刊：Nature Communications
DOI：10.1038/s41467-022-35557-y
影响因子 ：17.7
引用产品： NCI-H1299 细胞 , NCI-H1975 细胞
-
LncRNA surfactant associated 1 activates large tumor suppressor kinase 1/Yes-associated protein pathway via modulating hypoxic exosome-delivered miR-4766–5p to inhibit lung adenocarcinoma metastasis (2022-10-22)
期刊：INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI：10.1016/j.biocel.2022.106317
影响因子 ：5.7
引用产品： 特级胎牛血清 , NCI-H1975 细胞 , A549 [A-549] 细胞 , NCI-H1975细胞专用培养基 , A549 [A-549]细胞专用培养基
-
Tumor-suppressive E3 ubiquitin ligase CHIP inhibits the PBK/ERK axis to repress stem cell properties and radioresistance in non-small cell lung cancer (2022-11-27)
期刊：APOPTOSIS
DOI：10.1007/s10495-022-01789-y
影响因子 ：5.6
引用产品： PC-9 细胞 , A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞 , BEAS-2B 细胞 , RPMI-1640 培养基 , BEAS-2B细胞专用培养基 , EGF/Urogastrone/URG, Human, Recombinant , FGF-2/ bFGF/ FGF-b (Q65I, C96S, N111G), Human, Recombinant
-
Prognostic Value of Genomic Instability of m 6 A-Related lncRNAs in Lung Adenocarcinoma (2022-03-03)
期刊：Frontiers in Cell and Developmental Biology
影响因子 ：5.5
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞
-
Comprehensive Analysis of a Novel Immune-Related Gene Signature in Lung Adenocarcinoma (2022-10-19)
期刊：Journal of Clinical Medicine
影响因子 ：5.0
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , Calu-3 细胞 , BEAS-2B 细胞 , MEM (含NEAA) 培养基
-
Guided Isolation of An Uncommon Cembranoid Orthoester, Sarcotortin A, and Three Skeletal Diverse Terpenoids from the Hainan Soft Coral Sarcophyton tortuosum Based on Molecular Networking Strategy (2022-12-23)
期刊：CHEMISTRY-A EUROPEAN JOURNAL
影响因子 ：5.0
引用产品： NCI-H1975 细胞 , A549 [A-549] 细胞 , MDA-MB-231 细胞 , NCI-H1299 细胞
-
Long non-coding RNA FAM83A antisense RNA 1 (lncRNA FAM83A-AS1) targets microRNA-141-3p to regulate lung adenocarcinoma cell proliferation, migration, invasion, and epithelial-mesenchymal transition progression (2022-02-14)
期刊：Bioengineered
DOI：10.1080/21655979.2022.2037871
影响因子 ：4.9
引用产品： NCI-H1975 细胞 , A549 [A-549] 细胞
-
IMP4 Silencing Inhibits the Malignancy of Lung Adenocarcinoma via ERK Pathway (2022-10-22)
期刊：Journal of Oncology
影响因子 ：4.5
引用产品： NCI-H1975 细胞 , NCI-H1299 细胞 , A549 [A-549] 细胞 , NCI-H23 细胞 , 16HBE 细胞
-
Long noncoding RNA OIP5-AS1 promotes the stemness of lung cancer cells through enhancing Oct4 mRNA stability (2022-01-19)
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.5
引用产品： BEAS-2B , NCI-H1299 细胞 , A549 [A-549] 细胞 , NCI-H1299细胞专用培养基 , A549 [A-549]细胞专用培养基 , BEAS-2B细胞专用培养基 , 293T [HEK-293T] 细胞 , NCI-H1975 细胞 , NCI-H596 细胞
-
DNA repair/recombination protein 54L promotes the progression of lung adenocarcinoma by activating mTORC1 pathway (2022-12-01)
期刊：Human Cell
DOI：10.1007/s13577-022-00832-z
影响因子 ：4.4
引用产品： NCI-H1299 细胞 , NCI-H23 细胞 , NCI-H1975 细胞 , 16HBE 细胞 , A549 [A-549] 细胞
-
SLC7A5 is a lung adenocarcinoma-specific prognostic biomarker and participates in forming immunosuppressive tumor microenvironment (2022-10-02)
期刊：Heliyon
DOI：10.1016/j.heliyon.2022.e10866
影响因子 ：3.8
引用产品： A549 [A-549] 细胞 , HCC827 细胞 , NCI-H1975 细胞 , PC-9 细胞
-
METTL3 promotes non-small cell lung cancer (NSCLC) cell proliferation and colony formation in a m6A-YTHDF1 dependent way (2022-08-25)
期刊：BMC Pulmonary Medicine
DOI：10.1186/s12890-022-02119-3
影响因子 ：3.3
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , HCC827 细胞 , NCI-H1975 细胞 , 人支气管上皮细胞 , 青霉素-链霉素溶液 (双抗)，100×
-
Mechanism of Key Ingredient of Astragalus membranaceus on Lung Adenocarcinoma via PI3K/AKT Signaling Clarified by Utilizing Network Pharmacology Approach and Experimental Validation (2022-08-31)
期刊：Chinese Journal of Integrative Medicine
影响因子 ：2.6
引用产品： NCI-H1975 细胞
-
Circular RNA Circ_0005962 Contributes to Lung Adenocarcinoma Cell Proliferation and Stem Cell Formation Through Sponging of miR-3611 and Modulating CYP24A1 Expression (2022-12-21)
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-022-10312-6
影响因子 ：2.2
引用产品： BEAS-2B 细胞 , A549 [A-549] 细胞 , HCC827 细胞 , NCI-H1975 细胞 , BEAS-2B细胞专用培养基 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100× , A549 [A-549]细胞专用培养基 , Ham's F-12K 培养基 , HCC827细胞专用培养基 , RPMI-1640 培养基 , NCI-H1975细胞专用培养基
-
USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway (2022-12-08)
期刊：Discover Oncology
DOI：10.1007/s12672-022-00600-3
影响因子 ：
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , NCI-H1299 细胞 , 16HBE 细胞 , NCI-H23 细胞
-
Thioredoxin reductase 1 inhibitor shikonin promotes cell necroptosis via SecTRAPs generation and oxygen-coupled redox cycling (2021-12-30)
期刊：Free Radical Biology And Medicine
DOI：10.1016/j.freeradbiomed.2021.12.314
影响因子 ：8.1
引用产品： MCF7 [MCF-7] 细胞 , A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞 , NCI-H1944 细胞
-
Plumbagin reduction by thioredoxin reductase 1 possesses synergy effects with GLUT1 inhibitor on KEAP1-mutant NSCLC cells (2021-12-23)
期刊：Biomedicine & Pharmacotherapy
DOI：10.1016/j.biopha.2021.112546
影响因子 ：7.4
引用产品： NCI-H1299 细胞 , NCI-H1944 细胞 , NCI-H1975 细胞 , A549 [A-549] 细胞
-
Erianin inhibits human lung cancer cell growth via PI3K/Akt/mTOR pathway in vitro and in vivo (2021-03-17)
期刊：Phytotherapy Research
DOI：10.1002/ptr.7154
影响因子 ：7.2
引用产品： NCI-H1975 细胞 , LLC [LL/2; LLC1] 细胞 , A549 [A-549] 细胞 , 293A 细胞
-
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling (2021-05-29)
期刊：Molecular Therapy-Oncolytics
DOI：10.1016/j.omto.2021.05.008
影响因子 ：5.7
引用产品： NCI-H1975 细胞 , NCI-H1395 细胞 , NCI-H520 细胞 , A549/DDP 细胞 , NCI-H1299 细胞
-
C1GALT1, Negatively Regulated by miR-181d-5p, Promotes Tumor Progression via Upregulating RAC1 in Lung Adenocarcinoma (2021-07-07)
期刊：Frontiers in Cell and Developmental Biology
影响因子 ：5.5
引用产品： BEAS-2B , A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞 , NCI-H441 细胞
-
Inhibition effect of oxyepiberberine isolated from Coptis chinensis franch. On non-small cell lung cancer based on a network pharmacology approach and experimental validation (2021-06-01)
期刊：Journal Of Ethnopharmacology
影响因子 ：5.4
引用产品： BEAS-2B , A549 [A-549] 细胞 , NCI-H1975 细胞
-
Exosomal Delivery of FTO Confers Gefitinib Resistance to Recipient Cells through ABCC10 Regulation in an m6A-dependent Manner (2021-02-09)
期刊：Molecular Cancer Research
DOI：10.1158/1541-7786.MCR-20-0541
影响因子 ：5.2
引用产品： PC-9 细胞 , NCI-H1975 细胞
-
TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT (2021-11-07)
期刊：Toxicology And Applied Pharmacology
DOI：10.1016/j.taap.2021.115793
影响因子 ：3.8
引用产品： BEAS-2B , A549 [A-549] 细胞 , NCI-H226 [H226] 细胞 , NCI-H520 细胞 , NCI-H1975 细胞
-
RNA editing enzyme adenosine deaminases acting on RNA 1 deficiency increases the sensitivity of non-small cell lung cancer cells to anlotinib by regulating CX3CR1-fractalkine expression (2021-07-28)
期刊：Drug Development Research
影响因子 ：3.8
引用产品： NCI-H1975 细胞 , A549/Tax 细胞 , 青霉素-链霉素-两性霉素B溶液 (100×)
-
Comprehensive analysis of an immune infiltrate-related competitive endogenous RNA network reveals potential prognostic biomarkers for non-small cell lung cancer (2021-12-02)
期刊：PLoS One
DOI：10.1371/journal.pone.0260720
影响因子 ：3.7
引用产品： 青霉素-链霉素溶液 (双抗)，100× , NCI-H1650 细胞 , NCI-H1975 细胞 , DMEM高糖 培养基
-
CircRNA circ_0008037 facilitates tumor growth and the Warburg effect via upregulating NUCKS1 by binding to miR-433-3p in non-small cell lung cancer (2021-12-01)
期刊：Thoracic Cancer
影响因子 ：3.5
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞 , BEAS-2B 细胞
-
Calponin 3 suppresses proliferation, migration and invasion of non?small cell lung cancer cells (2021-07-01)
期刊：Oncology Letters
影响因子 ：2.9
引用产品： PC-9 细胞 , NCI-H1975 细胞 , NCI-H520 细胞
-
Long noncoding RNA LINC00968 inhibits proliferation, migration and invasion of lung adenocarcinoma through targeting miR-22-5p/CDC14A axis (2021-09-14)
期刊：3 BIOTECH
DOI：10.1007/s13205-021-02981-8
影响因子 ：2.9
引用产品： A549 [A-549] 细胞 , NCI-H1975 细胞
-
Anticancer roles of let?7f?1?3p in non?small cell lung cancer via direct targeting of integrin β1 (2021-09-16)
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.7
引用产品： NCI-H1975 细胞
-
Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275 (2020-12-31)
期刊：Bioengineered
DOI：10.1080/21655979.2020.1860492
影响因子 ：4.9
引用产品： Ham's F-12K 培养基 , A549 [A-549] 细胞 , SK-MES-1 细胞 , NCI-H1437 细胞 , NCI-H1975 细胞
-
SLC6A8 is involved in the progression of non-small cell lung cancer through the Notch signaling pathway (2020-10-27)
期刊：Annals of Translational Medicine
影响因子 ：3.6
引用产品： NCI-H1975 细胞 , NCI-H520 细胞 , NCI-H1299 细胞 , A549 [A-549] 细胞
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Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p (2020-01-10)
期刊：Pathology Research and Practice
影响因子 ：2.8
引用产品： A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞 , NCI-H2170 细胞
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Long noncoding RNA FBXL19‐AS1 induces tumor growth and metastasis by sponging miR‐203a‐3p in lung adenocarcinoma (2019-09-20)
期刊：Journal of Cellular Physiology
影响因子 ：5.6
引用产品： NCI-H1975 细胞
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EGFR mutation status in Tunisian non-small-cell lung cancer patients evaluated by mutation-specific immunohistochemistry (2018-08-09)
期刊：BMC Pulmonary Medicine
影响因子 ：3.1
引用产品： A549 [A-549] 细胞 , NCI-H1650 细胞 , NCI-H1975 细胞
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LncRNA CCAT2 promotes tumorigenesis by over-expressed Pokemon in non-small cell lung cancer (2017-01-12)
期刊：Biomedicine & Pharmacotherapy
DOI：10.1016/j.biopha.2016.12.122
影响因子 ：7.5
引用产品： PC-9 细胞 , NCI-H358 细胞 , NCI-H1975 细胞 , HBE135-E6E7 细胞
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Novel 4-anilinoquinazoline derivatives featuring an 1-adamantylmoiety as potent EGFR inhibitors with enhanced activity againstNSCLC cell lines (2016-01-26)
期刊：European Journal of Medicinal Chemistry
DOI：10.1016/j.ejmech.2016.01.045
影响因子 ：6.7
引用产品： A-431 细胞 , HCC827 细胞 , NCI-H1975 细胞 , A549 [A-549] 细胞 , MCF7 [MCF-7] 细胞
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