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产品概述
| 名称 | PANC-1 (人胰腺癌细胞) (STR鉴定正确) |
| 别称 | Panc-1; PANC.1; Panc 1; PanC1; Panc1; PANC1; Panc-1-P |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | 这株人胰腺癌细胞株PANC-1源自于胰腺癌导管细胞。PANC-1细胞倍增时间为52小时，G6PD活性处于低泳动性的B型。染色体研究表明，PANC-1细胞模式数目为63，包括3个独特标记的染色体和1个小环状染色体。PANC-1细胞的生长可被1U/ml的左旋天冬酰胺酶抑制；PANC-1细胞能在软琼脂上生长，亦能在裸鼠上成瘤。 |
| 年龄（性别） | 男性；56岁 |
| 组织来源 | 胰腺；胰管；上皮细胞癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胰腺癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~38-56 hours |
| 保藏机构 | ATCC; CRL-1469 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 10,12 D2S1338 23,24 D3S1358 17 D5S818 11,13 D7S820 8,10 D8S1179 14,15 D13S317 11 D16S539 11,12 D18S51 12 D19S433 11,16 D21S11 28 FGA 21 PentaD 14 PentaE 7,14 TH01 7,8 TPOX 8,11 vWA 15 D6S1043 11,12 D12S391 22 D2S441 10,14 -
STR鉴定图
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参考文献
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Engineered hypoxia-responsive albumin nanoparticles mediating mitophagy regulation for cancer therapy (2025-01-11)
期刊：Nature Communications
DOI：10.1038/s41467-025-55905-y
影响因子 ：14.7
引用产品： MCF7 [MCF-7] 细胞 , B16 细胞 , CT26.WT 细胞 , 4T1 细胞 , PANC-1 细胞
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Chemically engineered antibodies for autophagy-based receptor degradation (2025-01-09)
期刊：Nature Chemical Biology
DOI：10.1038/s41589-024-01803-1
影响因子 ：12.9
引用产品： Hela 细胞 , MDA-MB-231 细胞 , U-87 MG 细胞 , A549 [A-549] 细胞 , PANC-1 细胞 , NCI-H292 细胞 , NCI-H1299 细胞 , NCI-H1975 细胞 , A-375 细胞 , HuH-7 细胞 , 293T [HEK-293T] 细胞
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FOXM1-Driven CKS1B Upregulation Promotes Pancreatic Cancer Progression and Therapeutic Resistance (2025-01-13)
期刊：International Journal of Biological Sciences
影响因子 ：8.2
引用产品： BxPC-3 细胞 , CFPAC-1 细胞 , MIA PaCa-2 细胞 , PANC-1 细胞 , Panc02 细胞 , PL45 细胞
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Fabrication of Gemcitabine and Mitoxantrone Loaded PLG/Mesoporous Silica Nanofibers: Investigation of In Vitro Drug Release and Anticancer Activity in Pancreatic Cancer Cells (2025-01-03)
期刊：BioNanoScience
DOI：10.1007/s12668-024-01657-w
影响因子 ：3.0
引用产品： PANC-1 细胞
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RNA-binding protein DAZAP1 accelerates the advancement of pancreatic cancer by inhibiting ferroptosis (2025-01-04)
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-024-02261-0
影响因子 ：2.8
引用产品： AsPC-1 细胞 , PANC-1 细胞 , SW 1990 细胞 , MIA PaCa-2 细胞
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Engineered extracellular vesicles for targeted reprogramming of cancer-associated fibroblasts to potentiate therapy of pancreatic cancer (2024-06-24)
期刊：Signal Transduction and Targeted Therapy
DOI：10.1038/s41392-024-01872-7
影响因子 ：40.8
引用产品： DMEM/F12 培养基 , 特级胎牛血清 , PANC-1 细胞
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TRIM29 facilitates gemcitabine resistance via MEK/ERK pathway and is modulated by circRPS29/miR-770-5p axis in PDAC (2024-03-12)
期刊：DRUG RESISTANCE UPDATES
DOI：10.1016/j.drup.2024.101079
影响因子 ：24.3
引用产品： SW 1990 细胞 , PANC-1 细胞
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Orchestrated desaturation reprogramming from stearoyl-CoA desaturase to fatty acid desaturase 2 in cancer epithelial-mesenchymal transition and metastasis (2024-12-25)
期刊：Cancer Communications
影响因子 ：20.1
引用产品： T24 [T-24] 细胞 , SW 780 [SW-780, SW780] 细胞 , MDA-MB-231 细胞 , MCF7 [MCF-7] 细胞 , PANC-1 细胞 , BxPC-3 细胞 , 293T [HEK-293T] 细胞
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HMGA2 alleviates ferroptosis by promoting GPX4 expression in pancreatic cancer cells (2024-03-16)
期刊：Cell Death & Disease
DOI：10.1038/s41419-024-06592-y
影响因子 ：9.0
引用产品： PANC-1 细胞 , MIA PaCa-2 细胞 , BxPC-3 细胞
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Concurrent inhibition of pBADS99 synergistically improves MEK inhibitor efficacy in KRASG12D-mutant pancreatic ductal adenocarcinoma (2024-02-26)
期刊：Cell Death & Disease
DOI：10.1038/s41419-024-06551-7
影响因子 ：9.0
引用产品： SW 1990 细胞 , PANC-1 细胞 , AsPC-1 细胞 , CFPAC-1 细胞
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Targeting Reprogrammed Cancer-Associated Fibroblasts with Engineered Mesenchymal Stem Cell Extracellular Vesicles for Pancreatic Cancer Treatment (2024-08-02)
期刊：Biomaterials Research
影响因子 ：8.1
引用产品： PANC-1 细胞
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Molecular mechanisms of pancreatic cancer liver metastasis: the role of PAK2 (2024-01-26)
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2024.1347683
影响因子 ：7.3
引用产品： PANC-1 细胞 , BxPC-3 细胞 , RPMI-1640 培养基
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Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G-Quadruplexes (2024-01-25)
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c01773
影响因子 ：7.3
引用产品： MIA PaCa-2 细胞 , DMEM高糖 培养基 , 293 [HEK-293] 细胞 , HPAF-II 细胞 , U-87 MG 细胞 , MEM (ATCC改良) 培养基 , PANC-1 细胞 , HCT 116 细胞 , HFL1 细胞
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CHES1 modulated tumorigenesis and senescence of pancreas cancer cells through repressing AKR1B10 (2024-05-06)
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI：10.1016/j.bbadis.2024.167214
影响因子 ：6.2
引用产品： PANC-1 细胞
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BNIP3+ fibroblasts associated with hypoxia and inflammation predict prognosis and immunotherapy response in pancreatic ductal adenocarcinoma (2024-10-14)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05674-x
影响因子 ：6.1
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RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial–mesenchymal transition (2024-10-26)
期刊：Cancer & Metabolism
DOI：10.1186/s40170-024-00362-2
影响因子 ：6.0
引用产品： CFPAC-1 细胞 , DMEM高糖 培养基 , PANC-1 细胞 , IMDM 培养基 , HPAF-II 细胞 , MIA PaCa-2 细胞
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Discovery of novel 2-substituted 2, 3-dihydroquinazolin-4(1H)-one derivatives as tubulin polymerization inhibitors for anticancer therapy: The in vitro and in vivo biological evaluation (2024-08-13)
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2024.116766
影响因子 ：6.0
引用产品： A549 [A-549] 细胞 , Hep G2 细胞 , U251 细胞 , PANC-1 细胞 , A-375 细胞
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Fasting-Mimicking Diet Prevents Pancreatic Carcinogenesis via Gut Microbiota and Metabolites (2024-11-08)
期刊：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 ：5.7
引用产品： PANC-1 细胞 , hTERT-HPNE 细胞 , BxPC-3 细胞 , MIA PaCa-2 细胞 , AsPC-1 细胞
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LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4 (2024-03-19)
期刊：Biology Direct
DOI：10.1186/s13062-024-00463-4
影响因子 ：5.5
引用产品： PANC-1 细胞 , BxPC-3 细胞 , Capan-2 细胞 , AsPC-1 细胞 , SW 1990 细胞 , HPED-6 细胞
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Preclinical evaluation of 89Zr/177Lu-labeled amatuximab for theranostic application in pancreatic ductal adenocarcinoma (2024-11-13)
期刊：INTERNATIONAL JOURNAL OF PHARMACEUTICS
DOI：10.1016/j.ijpharm.2024.124946
影响因子 ：5.3
引用产品： MIA PaCa-2 细胞 , CFPAC-1 细胞 , PANC-1 细胞
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MFG-E8 induces epithelial-mesenchymal transition and anoikis resistance to promote the metastasis of pancreatic cancer cells (2024-02-29)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2024.176462
影响因子 ：5.0
引用产品： MIA PaCa-2 细胞 , PANC-1 细胞 , DMEM高糖 培养基 , 特级胎牛血清
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Cancer-associated fibroblast-derived MMP11 promotes tumor progression in pancreatic cancer (2024-12-05)
期刊：CANCER SCIENCE
影响因子 ：4.5
引用产品： AsPC-1 细胞 , BxPC-3 细胞 , PANC-1 细胞 , RPMI-1640 培养基 , DMEM高糖 培养基 , 青霉素-链霉素溶液（双抗），100×
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In Vitro evaluation of the anti-pancreatic cancer activity of epimedium herb (2024-07-01)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2024.1389221
影响因子 ：4.4
引用产品： PANC-1 细胞
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Glutathione S-transferase-Pi 1 protects cells from irradiation-induced death by inhibiting ferroptosis in pancreatic cancer (2024-09-11)
期刊：FASEB JOURNAL
影响因子 ：4.4
引用产品： PATU8988 细胞 , PANC-1 细胞
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Construction and validation of a pancreatic cancer prognostic model based on genes related to the hypoxic tumor microenvironment (2024-09-28)
期刊：WORLD JOURNAL OF GASTROENTEROLOGY
影响因子 ：4.3
引用产品： PANC-1 细胞 , hTERT-HPNE 细胞
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HnRNPAB promotes pancreatic ductal adenocarcinoma extravasation and liver metastasis by stablizing MYC mRNA (2024-07-05)
期刊：MOLECULAR CANCER RESEARCH
DOI：10.1158/1541-7786.MCR-24-0110
影响因子 ：4.1
引用产品： AsPC-1 细胞 , BxPC-3 细胞 , PANC-1 细胞 , MIA PaCa-2 细胞 , HUV-EC-C [HUVEC] 细胞
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ITGB6 promotes pancreatic fibrosis and aggravates the malignant process of pancreatic cancer via JAK2/STAT3 signaling pathway (2024-02-28)
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-024-03003-z
影响因子 ：3.6
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Identification of PSMD2 as a promising biomarker for pancreatic cancer patients based on comprehensive bioinformatics and in vitro studies (2024-11-05)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e40117
影响因子 ：3.4
引用产品： Leibovitz's L-15 培养基 , 马血清 , PANC-1 细胞 , 青霉素-链霉素溶液（双抗），100× , SW 1990 细胞 , MIA PaCa-2 细胞
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Golgi protein ACBD3 downregulation sensitizes cells to ferroptosis (2024-07-02)
期刊：CELL BIOLOGY INTERNATIONAL
影响因子 ：3.3
引用产品： PANC-1 细胞
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MLPH regulates EMT in pancreatic adenocarcinoma through the PI3K-AKT signaling pathway (2024-09-09)
期刊：Journal of Cancer
影响因子 ：3.3
引用产品： PANC-1 细胞
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Enhancing therapeutic efficacy in homologous recombination-proficient pancreatic cancer via the combination of PARP1-PROTAC and a BRD4 inhibitor (2024-10-26)
期刊：BIOORGANIC & MEDICINAL CHEMISTRY
影响因子 ：3.3
引用产品： BxPC-3 细胞 , PANC-1 细胞 , Capan-1 细胞
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The BCL2-associated athanogene-3–Interferon-induced transmembrane protein 2 axis enhances pancreatic ductal adenocarcinoma growth via the Mitogen-activated protein kinase signaling pathway (2024-08-30)
期刊：CARCINOGENESIS
影响因子 ：3.3
引用产品： MIA PaCa-2 细胞 , PANC-1 细胞 , SU.86.86 细胞 , BxPC-3 细胞 , NK-92 细胞
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FAM53B promotes pancreatic ductal adenocarcinoma metastasis by regulating macrophage M2 polarization (2024-04-15)
期刊：World Journal of Gastrointestinal Oncology
影响因子 ：3.0
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Establishment of a Prognostic Model for Pancreatic Cancer Based on Hypoxia-Related Genes (2024-10-21)
期刊：TECHNOLOGY IN CANCER RESEARCH & TREATMENT
影响因子 ：2.7
引用产品： PANC-1 细胞 , DMEM/F12无糖 培养基
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GPX3 represses pancreatic cancer cell proliferation, migration and invasion, and improves their chemo?sensitivity by regulating the JNK/c?Jun signaling pathway (2024-01-29)
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.7
引用产品： BxPC-3 细胞 , SW 1990 细胞 , PANC-1 细胞
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CD8?+?T-Cell-Related Genes: Deciphering Their Role in the Pancreatic Adenocarcinoma TME and Their Effect on Prognosis (2024-11-27)
期刊：DIGESTIVE DISEASES AND SCIENCES
DOI：10.1007/s10620-024-08715-z
影响因子 ：2.5
引用产品： PANC-1 细胞
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THBS1 knockdown suppresses pancreatic cancer progression through JAK2/STAT3 signaling pathway (2024-12-26)
期刊：MOLECULAR AND CELLULAR PROBES
影响因子 ：2.3
引用产品： PANC-1 细胞
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Prognostic biomarker MICAL2 and associates with proliferation, migration and immune infiltration in pancreatic adenocarcinoma (2024-12-11)
期刊：JOURNAL OF APPLIED GENETICS
DOI：10.1007/s13353-024-00919-3
影响因子 ：2.0
引用产品： BxPC-3 细胞 , SW 1990 细胞 , PANC-1 细胞 , AsPC-1 细胞
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Deciphering the molecular mechanism of long non-coding RNA HIF1A-AS1 regulating pancreatic cancer cells (2024-04-29)
期刊：Annals of Medicine and Surgery
DOI：10.1097/MS9.0000000000002097
影响因子 ：1.7
引用产品： PANC-1 细胞 , PATU8988 细胞 , SW 1990 细胞 , HPDE6-C7 细胞
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Dual-crosslinking immunostimulatory hydrogel synchronously suppresses pancreatic fistula and pancreatic cancer relapse post-resection (2023-12-24)
期刊：BIOMATERIALS
DOI：10.1016/j.biomaterials.2023.122453
影响因子 ：14.0
引用产品： PANC-1 细胞 , HPDE6-C7 细胞
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MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression (2023-10-31)
期刊：EMBO JOURNAL
影响因子 ：11.4
引用产品： 293T [HEK-293T] 细胞 , PANC-1 细胞 , CFPAC-1 细胞 , BxPC-3 细胞 , SW 1990 细胞
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METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation (2023-03-28)
期刊：Cell Death & Disease
DOI：10.1038/s41419-023-05715-1
影响因子 ：9.0
引用产品： SW 1990 细胞 , PANC-1 细胞 , BxPC-3 细胞
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Local Sustained Chemotherapy of Pancreatic Cancer Using Endoscopic Ultrasound-Guided Injection of Biodegradable Thermo-Sensitive Hydrogel (2023-07-19)
期刊：International Journal of Nanomedicine
影响因子 ：8.0
引用产品： PANC-1 细胞
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Diterpenoid honatisine overcomes temozolomide resistance in glioblastoma by inducing mitonuclear protein imbalance through disruption of TFAM-mediated mtDNA transcription (2023-12-29)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2023.155328
影响因子 ：7.9
引用产品： SK-OV-3 细胞 , Caco-2 细胞 , PANC-1 细胞 , PC-3 细胞 , NCI-H1395 细胞 , MCF7 [MCF-7] 细胞
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Dissection of pyroptosis-related prognostic signature and CASP6-mediated regulation in pancreatic adenocarcinoma: new sights to clinical decision-making (2023-03-07)
期刊：APOPTOSIS
DOI：10.1007/s10495-023-01823-7
影响因子 ：7.2
引用产品： PANC-1 细胞
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AKR7A3 modulates the metastasis of pancreatic ductal adenocarcinoma through regulating PHGDH‐suppressed autophagy (2023-05-29)
期刊：CANCER SCIENCE
影响因子 ：5.7
引用产品： PANC-1 细胞 , MIA PaCa-2 细胞
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The ALOX5 inhibitor Zileuton regulates tumor-associated macrophage M2 polarization by JAK/STAT and inhibits pancreatic cancer invasion and metastasis (2023-06-20)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110505
影响因子 ：5.6
引用产品： PANC-1 细胞
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5′-tRF-19-Q1Q89PJZ Suppresses the Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating Hexokinase 1-Mediated Glycolysis (2023-10-12)
期刊：Biomolecules
影响因子 ：5.5
引用产品： MIA PaCa-2 细胞 , PANC-1 细胞 , CFPAC-1 细胞 , Capan-2 细胞 , SW 1990 细胞 , BxPC-3 细胞 , AsPC-1 细胞 , 人胰腺上皮细胞
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Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2 (2023-07-24)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：5.3
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COL12A1 Acts as a Novel Prognosis Biomarker and Activates Cancer-Associated Fibroblasts in Pancreatic Cancer through Bioinformatics and Experimental Validation (2023-02-26)
期刊：Cancers
影响因子 ：5.2
引用产品： PANC-1 细胞 , BxPC-3 细胞 , CFPAC-1 细胞 , PATU8988 细胞 , AsPC-1 细胞 , MIA PaCa-2 细胞
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Identifying endoplasmic reticulum stress-related molecular subtypes and prognostic model for predicting the immune landscape and therapy response in pancreatic cancer (2023-10-09)
期刊：Aging-US
影响因子 ：5.2
引用产品： CFPAC-1 细胞 , PANC-1 细胞
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Identification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments (2023-01-14)
期刊：Chinese Medicine
DOI：10.1186/s13020-023-00710-2
影响因子 ：4.9
引用产品： PANC-1 细胞
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Identification of a chemoresistance-related prognostic gene signature by comprehensive analysis and experimental validation in pancreatic cancer (2023-05-12)
期刊：Frontiers in Oncology
影响因子 ：4.7
引用产品： AsPC-1 细胞 , CFPAC-1 细胞 , PANC-1 细胞 , IMDM 培养基 , DMEM高糖 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100×
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PANoptosis-related molecular subtype and prognostic model associated with the immune microenvironment and individualized therapy in pancreatic cancer (2023-07-14)
期刊：Frontiers in Oncology
影响因子 ：4.7
引用产品： PANC-1 细胞 , CFPAC-1 细胞
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Identification and characterization of interferon-γ signaling-based personalized heterogeneity and therapeutic strategies in patients with pancreatic cancer (2023-10-24)
期刊：Frontiers in Oncology
影响因子 ：4.7
引用产品： BxPC-3 细胞 , PANC-1 细胞 , CFPAC-1 细胞 , MIA PaCa-2 细胞
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Effects of anoxic prognostic model on immune microenvironment in pancreatic cancer (2023-06-05)
期刊：Scientific Reports
DOI：10.1038/s41598-023-36413-9
影响因子 ：4.6
引用产品： PANC-1 细胞
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Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis (2023-10-30)
期刊：BMC CANCER
DOI：10.1186/s12885-023-11557-z
影响因子 ：3.8
引用产品： MIA PaCa-2 细胞 , PANC-1 细胞 , AsPC-1 细胞 , BxPC-3 细胞 , THP-1 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , 特级胎牛血清 , 马血清 , 青霉素-链霉素溶液 (双抗)，100× , β-巯基乙醇 (55mM)，1000×
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Circadian Genes MBOAT2/CDA/LPCAT2/B4GALT5 in the Metabolic Pathway Serve as New Biomarkers of PACA Prognosis and Immune Infiltration (2023-04-30)
期刊：Life-Basel
影响因子 ：3.2
引用产品： PANC-1 细胞 , DMEM高糖 培养基
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A prospective prognostic signature for pancreatic adenocarcinoma based on ubiquitination-related mRNA-lncRNA with experimental validation in vitro and vivo (2023-08-04)
期刊：FUNCTIONAL & INTEGRATIVE GENOMICS
DOI：10.1007/s10142-023-01158-1
影响因子 ：2.9
引用产品： CFPAC-1 细胞 , PANC-1 细胞 , IMEM
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Comprehensive pan-cancer analysis of role of GPRASP1, associated with clinical outcomes, immune microenvironment, and immunotherapeutic efficiency in pancreatic cancer (2023-02-12)
期刊：PATHOLOGY RESEARCH AND PRACTICE
影响因子 ：2.8
引用产品： PANC-1 细胞 , MIA PaCa-2 细胞 , BxPC-3 细胞 , SW 1990 细胞 , AsPC-1 细胞
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ZMAT1 acts as a tumor suppressor in pancreatic ductal adenocarcinoma by inducing SIRT3/p53 signaling pathway (2022-04-07)
期刊：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI：10.1186/s13046-022-02310-8
影响因子 ：11.3
引用产品： PANC-1 细胞 , BxPC-3 细胞 , Capan-2 细胞 , SW 1990 细胞 , AsPC-1 细胞
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Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription (2022-02-18)
期刊：Journal Of Experimental & Clinical Cancer Research
DOI：10.1186/s13046-022-02260-1
影响因子 ：11.3
引用产品： Hs 578T 细胞 , BT-549 细胞 , HCT-15 细胞 , MCF 10A 细胞 , A549 [A-549] 细胞 , SK-OV-3 细胞 , Hela 细胞 , PANC-1 细胞
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System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma (2022-10-05)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-022-03632-z
影响因子 ：8.4
引用产品： CFPAC-1 细胞 , PANC-1 细胞
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6-Shogaol Exhibits a Promoting Effect with Tax via Binding HSP60 in Non-Small-Cell Lung Cancer (2022-11-19)
期刊：Cells
影响因子 ：7.7
引用产品： A-375 细胞 , A549 [A-549] 细胞 , H8 细胞 , U251 细胞 , 3T3-L1 细胞 , PANC-1 细胞 , TSSCA 细胞 , HK-2 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基
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Exosomal LINC00460/miR-503-5p/ANLN positive feedback loop aggravates pancreatic cancer progression through regulating T cell–mediated cytotoxicity and PD-1 checkpoint (2022-12-08)
期刊：Cancer Cell International
DOI：10.1186/s12935-022-02741-5
影响因子 ：6.4
引用产品： AsPC-1 细胞 , BxPC-3 细胞 , SW 1990 细胞 , PANC-1 细胞 , MIA PaCa-2 细胞 , THP-1 细胞
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Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2 (2022-09-20)
期刊：BIOCHEMICAL PHARMACOLOGY
影响因子 ：6.1
引用产品： PANC-1 细胞 , MIA PaCa-2 细胞 , BxPC-3 细胞 , AsPC-1 细胞 , CFPAC-1 细胞 , SW 1990 细胞 , CFPAC-1细胞专用培养基 , SW 1990细胞专用培养基 (L15)
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Deciphering the action mechanism of paeoniflorin in suppressing pancreatic cancer: A network pharmacology study and experimental validation (2022-10-20)
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2022.1032282
影响因子 ：6.0
引用产品： PANC-1 细胞 , Capan-2 细胞
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Anti?silencing function 1B promotes the progression of pancreatic cancer by activating c?Myc (2022-11-17)
期刊：INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子 ：5.9
引用产品： CFPAC-1 细胞 , HPAF-II 细胞 , 马血清 , IMDM 培养基 , PANC-1 细胞 , MEM（含NEAA） 培养基 , MIA PaCa-2 细胞
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PARP1 controls the transcription of CD24 by ADP-ribosylating the RNA helicase DDX5 in pancreatic cancer (2022-12-28)
期刊：INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI：10.1016/j.biocel.2022.106358
影响因子 ：5.7
引用产品： Capan-1 细胞 , PANC-1 细胞
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Pyroptosis regulators exert crucial functions in prognosis, progression and immune microenvironment of pancreatic adenocarcinoma: a bioinformatic and in vitro research (2022-01-08)
期刊：Bioengineered
DOI：10.1080/21655979.2021.2019873
影响因子 ：4.9
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GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma (2022-06-05)
期刊：PANCREATOLOGY
影响因子 ：4.0
引用产品： AsPC-1 细胞 , BxPC-3 细胞 , PANC-1 细胞 , MIA PaCa-2 细胞 , SW 1990 细胞
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Identification by genetic algorithm optimized back propagation artificial neural network and validation of a four-gene signature for diagnosis and prognosis of pancreatic cancer (2022-11-09)
期刊：Heliyon
DOI：10.1016/j.heliyon.2022.e11321
影响因子 ：3.8
引用产品： PANC-1 细胞
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Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis (2022-10-06)
期刊：KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
影响因子 ：3.0
引用产品： PANC-1 细胞 , AsPC-1 细胞 , DMEM高糖 培养基 , RPMI-1640 培养基 , 特级胎牛血清 , 青霉素-链霉素溶液 (双抗)，100×
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Construction and validation of a m6A RNA methylation and ferroptosis-related prognostic model for pancreatic cancer by integrated bioinformatics analysis. (2022-10-01)
期刊：Journal of Gastrointestinal Oncology
影响因子 ：2.6
引用产品： CFPAC-1 细胞 , PANC-1 细胞 , BxPC-3 细胞
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Identification of a Pyroptosis-Related Gene Signature and Effect of Silencing the CHMP4C and CASP4 in Pancreatic Adenocarcinoma (2022-11-14)
期刊：International Journal of General Medicine
影响因子 ：2.1
引用产品： PANC-1 细胞
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SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis (2021-07-24)
期刊：Cancer Letters
DOI：10.1016/j.canlet.2021.07.035
影响因子 ：9.7
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A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation (2021-11-22)
期刊：Chinese Medicine
DOI：10.1186/s13020-021-00534-y
影响因子 ：4.9
引用产品： PANC-1 细胞
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Exosomal lncRNA UCA1 Derived From Pancreatic Stellate Cells Promotes Gemcitabine Resistance in Pancreatic Cancer via the SOCS3/EZH2 Axis (2021-11-19)
期刊：Frontiers in Oncology
影响因子 ：4.7
引用产品： PANC-1 细胞 , 293T [HEK-293T] 细胞
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CMTM3 Overexpression Predicts Poor Survival and Promotes Proliferation and Migration in Pancreatic Cancer (2021-08-03)
期刊：Journal of Cancer
影响因子 ：3.9
引用产品： SW 1990 细胞 , AsPC-1 细胞 , PANC-1 细胞 , BxPC-3 细胞 , Capan-2 细胞
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TFAP2A-induced SLC2A1-AS1 promotes cancer cell proliferation (2021-02-19)
期刊：Biological Chemistry
影响因子 ：3.7
引用产品： SK-MES-1 细胞 , PANC-1 细胞
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Targeting the EZH2-PPAR Axis Is a Potential Therapeutic Pathway for Pancreatic Cancer (2021-07-22)
期刊：PPAR Research
影响因子 ：2.9
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MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation (2020-01-21)
期刊：Frontiers in Oncology
影响因子 ：4.7
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Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway (2020-03-10)
期刊：Journal Of Physiology And Biochemistry
DOI：10.1007/s13105-020-00734-4
影响因子 ：3.4
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Pancreatic cancer cell apoptosis is induced by a proteoglycan extracted from Ganoderma lucidum (2020-11-12)
期刊：Oncology Letters
影响因子 ：2.9
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Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells (2020-05-20)
期刊：Bioscience Biotechnology And Biochemistry
DOI：10.1080/09168451.2020.1762479
影响因子 ：1.6
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A gold–selenium-bonded nanoprobe for real-time in situ imaging of the upstream and downstream relationship between uPA and MMP-9 in cancer cells (2019-03-16)
期刊：Chem Commun
影响因子 ：4.9
引用产品： MCF7 [MCF-7] 细胞 , PANC-1 细胞
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Grape seed proanthocyanidins inhibit proliferation of pancreatic cancer cells by modulating microRNA expression (2019-01-04)
期刊：Oncology Letters
影响因子 ：2.9
引用产品： PANC-1 细胞
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Simultaneous Fluorescence Visualization of Epithelial-Mesenchymal Transition and Apoptosis Processes in Tumor Cells for Evaluating the Impact of Epithelial-Mesenchymal Transition on Drug Efficacy (2018-09-18)
期刊：Analytical Chemistry
DOI：10.1021/acs.analchem.8b02494
影响因子 ：7.4
引用产品： MCF 10A 细胞 , MDA-MB-231 细胞 , PANC-1 细胞
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Transcriptome analysis of pancreatic cancer cell response to treatment with grape seed proanthocyanidins (2018-12-06)
期刊：Oncology Letters
影响因子 ：2.9
引用产品： PANC-1 细胞
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