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产品概述
名称 | HCC827 (人非小细胞肺癌细胞) (STR鉴定正确) |
别称 | HCC-827; HCC0827 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | HCC827细胞是于1994年3月建系,组织提供者在25岁到26岁时每个月抽1包烟,在诊断前12年不再抽烟。HCC827细胞在EGFR酪氨酸激酶区域有一个获得性突变(E746-A750缺失)。 |
年龄(性别) | 女性;39岁 |
组织来源 | 肺腺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肺癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~28-60 hours |
保藏机构 | ATCC; CRL-2868 BCRJ; 0351 DSMZ; ACC-566 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11 D2S1338 17,24 D3S1358 17 D5S818 12 D7S820 11,12 D8S1179 12 D13S317 9 D16S539 12 D18S51 13 D19S433 14 D21S11 31 FGA 22,24 PentaD 14 PentaE 20 TH01 6 TPOX 8 vWA 18 D6S1043 11,12 D12S391 17 D2S441 11,11.3 -
STR鉴定图
参考文献
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UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment(2024/02/08)
作者:Yin Li, Manling Jiang, Ling Aye
期刊:Nature Communications
DOI:10.1038/s41467-024-45340-w
影响因子 :16.600
引用产品:CL-0094
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Targeting TYK2 alleviates Rab27A-induced malignant progression of non-small cell lung cancer via disrupting IFNα-TYK2-STAT-HSPA5 axis(2024/03/23)
作者:Yuanyuan Zeng, Jian Zhao, Zhengyan Wu
期刊:npj Precision Oncology
DOI:10.1038/s41698-024-00574-1
影响因子 :7.900
引用产品:CL-0094
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A two-circular RNA signature as a noninvasive diagnostic biomarker for lung adenocarcinoma(2019/02/18)
作者:Xiaoxia Liu, Yie Yang, Xiao Liu
期刊:Journal of Translational Medicine
影响因子 :7.400
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NEAT1_1 confers gefitinib resistance in lung adenocarcinoma through promoting AKR1C1-mediated ferroptosis defence(2024/03/12)
作者:Shuman Zhen, Yunlong Jia, Yan Zhao
期刊:Cell Death Discovery
DOI:10.1038/s41420-024-01892-w
影响因子 :7.000
引用产品:CL-0094
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Novel 4-anilinoquinazoline derivatives featuring an 1-adamantylmoiety as potent EGFR inhibitors with enhanced activity againstNSCLC cell lines(2016/01/26)
作者:Haiqing Yu, Yanxia Li, Yang Ge
期刊:European Journal of Medicinal Chemistry
DOI:DOI: 10.1016/j.ejmech.2016.01.045
影响因子 :6.700
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Anticancer effect of covalent purine-containing EGFR TKI, ZZC4 and its mechanism of action through network pharmacology(2023/11/27)
作者:Mawusse K.I. Attiogbe, Hongyi Zhao
期刊:LIFE SCIENCES
影响因子 :6.100
引用产品:CL-0094
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Celastrus orbiculatus Thunb. extract targeting DJ-1 inhibits non-small cell lung cancer invasion and metastasis through mitochondrial-induced ROS accumulation(2023/07/20)
作者:Xiaochen Ni, Shilong Yu, Xiaomin Jiang
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.400
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Hsa_circ_0006677 regulates special AT-rich binding protein-2-mediated tumor-suppressive effect via functioning as a miR-1245a sponge in non-small cell lung cancer(2022/01/26)
作者:Xizhong Sui, Zongzhi Liu, Lei Niu
期刊:Bioengineered
DOI:10.1080/21655979.2022.2031400
影响因子 :4.900
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SLC7A5 is a lung adenocarcinoma-specific prognostic biomarker and participates in forming immunosuppressive tumor microenvironment(2022/10/02)
作者:Yong Liu, Guoyuan Ma, Jichang Liu
期刊:Heliyon
DOI:10.1016/j.heliyon.2022.e10866
影响因子 :4.000
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CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway(2021/11/12)
作者:Decai Chi, Dong Wang, Minghui Zhang
期刊:Experimental Cell Research
DOI:10.1016/j.yexcr.2021.112914
影响因子 :3.700
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Proteasome 26S subunit, non-ATPase 1 (PSMD1) facilitated the progression of lung adenocarcinoma by the de-ubiquitination and stability of PTEN-induced kinase 1 (PINK1)(2022/02/19)
作者:Lihua Liu, Aihua Liu, Jun Dong
期刊:Experimental Cell Research
DOI:10.1016/j.yexcr.2022.113075
影响因子 :3.700
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Multi-omics analysis of expression profile and prognostic values of connexin family in LUAD(2023/07/17)
作者:Peng Jiang, Xingfa Huo, Bowen Dong
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-023-05075-5
影响因子 :3.600
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Circ_0006324 regulates cell proliferation, cell-cycle progression, apoptosis, and glycolysis of non-small cell lung cancer cells through miR-496/TRIM59 axis(2023/08/07)
作者:Tao Wang, Xu Zhu, Kai Wang
期刊:JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影响因子 :3.600
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KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification(2024/02/07)
作者:Zhixiang Zhang, Jipeng Guo, Chongwen Gong
期刊:Cancer Biomarkers
影响因子 :3.100
引用产品:CL-0094
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IGF2BP1 enhances the stability of SIK2 mRNA through m6A modification to promote non-small cell lung cancer progression(2023/10/12)
作者:Yan Xu, Li Xu, Yi Kong
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.10.045
影响因子 :3.100
引用产品:CL-0094
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Antioncogenic roles of USP9Y and DDX3Y in lung cancer: USP9Y stabilizes DDX3Y by preventing its degradation through deubiquitination(2024/01/12)
作者:Lei Xiu, Bo Ma, Lili Ding
期刊:ACTA HISTOCHEMICA
DOI:10.1016/j.acthis.2023.152132
影响因子 :2.500
引用产品:CL-0094
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CircSFMBT2 Plays an Oncogenic Role in Lung Adenocarcinoma Depending on the miR-1305/SALL4 Axis(2023/12/21)
作者:Xuan Zhao, Xiaojing Xing, Yongkai Wu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-023-10611-6
影响因子 :2.400
引用产品:CL-0094
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Circ-NUP98 Promotes Lung Adenocarcinoma Development Through Regulating CBX1 by miR-188-3p(2023/12/21)
作者:Jie Mei, Jing Zuo, Jiazhuan Mei
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-023-10609-0
影响因子 :2.400
引用产品:CL-0094
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Circular RNA Circ_0005962 Contributes to Lung Adenocarcinoma Cell Proliferation and Stem Cell Formation Through Sponging of miR-3611 and Modulating CYP24A1 Expression(2022/12/21)
作者:Wenjing Lu, Zhigao Yu, Jun Liu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10312-6
影响因子 :2.400
引用产品:164210-50 CL-0016 CL-0094 CL-0298 CM-0016 CM-0094 CM-0298 PB180120 PM150110 PM150210 PM150910
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Overexpression of Human Aspartyl (Asparaginyl) β-hydroxylase in NSCLC: Its Diagnostic Value by Means of Exosomes of Bronchoalveolar Lavage(2021/11/01)
作者:Haohao Zhu, Huai Liu, Jianfeng Wen
期刊:Applied Immunohistochemistry & Molecular Morphology
DOI:10.1097/PAI.0000000000000963
影响因子 :1.600
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RBM10 Is a Biomarker Associated with Pan-Cancer Prognosis and Immune Infiltration: System Analysis Combined with In Vitro and Vivo Experiments(2022/11/28)
作者:Yingyue Cao, Luyi Pang, Shi Jin
期刊:Oxidative Medicine and Cellular Longevity
影响因子 :0.000
引用产品:CL-0094
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