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产品概述
名称 | NCI-H226 [H226] (人肺鳞癌细胞) (STR鉴定正确) |
别称 | NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | NCI-H226 [H226]细胞是于1980年分离建立的。 |
年龄(性别) | 男性 |
组织来源 | 肺;源自转移部位:胸腔积液 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肺癌细胞 |
生物安全等级 | BSL-1 |
倍增时间 | ~60 hours |
保藏机构 | ATCC; CRL-5826 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,11 D2S1338 25 D3S1358 16 D5S818 11,12 D7S820 8,10 D8S1179 14,15 D13S317 13,14 D16S539 9,12 D18S51 16 D19S433 15 D21S11 29,32.2 FGA 20,23 PentaD 9,10 PentaE 12,15 TH01 8,9.3 TPOX 8,11 vWA 17 D6S1043 13,18 D12S391 22 D2S441 14 -
STR鉴定图
参考文献
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circNOX4 activates an inflammatory fibroblast niche to promote tumor growth and metastasis in NSCLC via FAP/IL-6 axis (2024-03-08)
作者:Yan Zhao:1.Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China. ; 2.Department of Oncology, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050011, China. ; Yunlong Jia:1.Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China. ; Jiali Wang:1.Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China. ; Xiaolin Chen:1.Department of Nuclear Medicine, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050011, China. ; Jingya Han:1.Department of Nuclear Medicine, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050011, China. ; Shuman Zhen:1.Department of Tumor Immu
期刊:circNOX4 activates an inflammatory fibroblast niche to promote tumor growth and metastasis in NSCLC via FAP/IL-6 axis
DOI:10.1186/s12943-024-01957-5
影响因子 :37.3
引用产品: A549 [A-549] 细胞 , PC-9 细胞 , NCI-H226 [H226] 细胞 , H1581 细胞 , BEAS-2B 细胞
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Targeting TYK2 alleviates Rab27A-induced malignant progression of non-small cell lung cancer via disrupting IFNα-TYK2-STAT-HSPA5 axis (2024-03-23)
作者:Yuanyuan Zeng:1.Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, 215006, Suzhou, China. ; 2.Institute of Respiratory Diseases, Soochow University, 215006, Suzhou, China. ; 3.Suzhou Key Laboratory for Respiratory Diseases, 215006, Suzhou, China. ; Jian Zhao:1.Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, 215006, Suzhou, China. ; Zhengyan Wu:1.Department of Health Management Center, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Suzhou, China. ; Yongkang Huang:1.Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, 215006, Suzhou, China. ; Anqi Wang:1.Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, 215006, Suzhou, China. ; Jianjie Zhu:1.Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, 21
期刊:Targeting TYK2 alleviates Rab27A-induced malignant progression of non-small cell lung cancer via disrupting IFNα-TYK2-STAT-HSPA5 axis
DOI:10.1038/s41698-024-00574-1
影响因子 :7.9
引用产品: 293T [HEK-293T] 细胞 , BEAS-2B 细胞 , NCI-H1299 细胞 , A549 [A-549] 细胞 , LTEP-α-2 细胞 , NCI-H226 [H226] 细胞 , Calu-3 细胞 , HCC827 细胞 , NCI-H1975 细胞
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Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer (2023-11-10)
作者:Li Zhang:1.Thoracic Surgery Laboratory, Xuzhou Medical University, Xuzhou, 221006, Jiangsu Province, China. ; 2.Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221006, Jiangsu Province, China. ; Jingtian Liang:1.Thoracic Surgery Laboratory, Xuzhou Medical University, Xuzhou, 221006, Jiangsu Province, China. ; 2.Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221006, Jiangsu Province, China. ; Hao Qin:1.Thoracic Surgery Laboratory, Xuzhou Medical University, Xuzhou, 221006, Jiangsu Province, China. ; 2.Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, Xuzhou, 221006, Jiangsu Province, China. ; Yin Lv:1.Thoracic Surgery Laboratory, Xuzhou Medical University, Xuzhou, 221006, Jiangsu Province, China. ; 2.Department of Thoracic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Road, X
期刊:Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer
DOI:10.1186/s13046-023-02875-y
影响因子 :11.3
引用产品: A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H292 细胞 , NCI-H23 细胞 , NCI-H1703 细胞 , NCI-H226 [H226] 细胞 , BEAS-2B 细胞
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TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation (2023-05-29)
作者:Yuening Sun:1.Guangdong Institute of Cardiovascular Diseases, Guangdong Key Laboratory of Vascular Diseases, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511436, P. R. China. ; 2.Guangdong Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, P. R. China. ; Peng Lin:1.Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, 215123, P. R. China. ; Xiumin Zhou:1.Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, P. R. China. ; Ying Ren:1.Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, 215123, P. R. China. ; Yuanming He:1.Guangdong Institute of Cardiovascular Diseases, Guangdong Key Laboratory of Vascular Diseases, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511436, P. R. China. ; Jingpei Liang:1.Guangdong Insti
期刊:TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation
影响因子 :9.2
引用产品: A549 [A-549] 细胞 , NCI-H226 [H226] 细胞
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TSTA3 overexpression promotes malignant characteristics in LUSC by regulating LAMP2-mediated autophagy and tumor microenvironment (2023-11-20)
作者:Yanlin Guo:1.Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China. ; Yanlong Hao:1.Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China. ; Liuyi Shen:1.Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China. ; Yu Du:1.Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China. ; Xiaohui Wang:1.Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China. ; Lvye Gao:1.Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China. ; Xuefei Feng:1.Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China. ; Yuanfang Zhai:1.Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, Shanxi, 030001,
期刊:TSTA3 overexpression promotes malignant characteristics in LUSC by regulating LAMP2-mediated autophagy and tumor microenvironment
DOI:10.1186/s12935-023-03109-z
影响因子 :5.8
引用产品: NCI-H226 [H226] 细胞 , NCI-H1703 细胞
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Celastrus orbiculatus Thunb. extract targeting DJ-1 inhibits non-small cell lung cancer invasion and metastasis through mitochondrial-induced ROS accumulation (2023-07-20)
作者:Xiaochen Ni:1.Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, PR China. Electronic address: nxc19970103@163.com. ; Shilong Yu:1.Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, 225001, PR China; Yangzhou Hospital of Traditional Chinese Medicine, Yangzhou, 225001, PR China. Electronic address: yushilong1992@163.com. ; Xiaomin Jiang:1.The Key Laboratory of Syndrome Differentiation and Treatment of Gastric Cancer of the State Administration of Traditional Chinese Medicine, Yangzhou, 225001, PR China; Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, 225001, PR China. Electronic address: 15050735732@139.com. ; Feng Wu:1.Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, PR China. Electronic address: yzwufeng888@163.com. ; Jun Zhou:1.D
期刊:Celastrus orbiculatus Thunb. extract targeting DJ-1 inhibits non-small cell lung cancer invasion and metastasis through mitochondrial-induced ROS accumulation
影响因子 :5.4
引用产品: NCI-H226 [H226] 细胞 , NCI-H520 细胞 , HCC827 细胞
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Tandem CAR-T cells targeting MUC1 and PSCA combined with anti-PD-1 antibody exhibit potent preclinical activity against non-small cell lung cancer (2023-08-29)
作者:Aying Wang:1.The First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, China; Department of Respiratory and Critical Care Medicine, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China. ; Tangfeng Lv:1.Department of Respiratory and Critical Care Medicine, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China. Electronic address: bairoushui@163.com. ; Yong Song:1.The First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, China; Department of Respiratory and Critical Care Medicine, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China. Electronic address: yong.song@nju.edu.cn. ;
期刊:Tandem CAR-T cells targeting MUC1 and PSCA combined with anti-PD-1 antibody exhibit potent preclinical activity against non-small cell lung cancer
DOI:10.1016/j.cellimm.2023.104760
影响因子 :4.3
引用产品: A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H226 [H226] 细胞 , NCI-H460 [H460] 细胞
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The antihypertensive felodipine shows synergistic activity with immune checkpoint blockade and inhibits tumor growth via NFAT1 in LUSC (2023-09-22)
作者:Si-Yu Liang:1.Department of Cardiology, The Fourth Affiliated Hospital of Guangzhou Medical University, Zengcheng, Guangzhou, China. ; Hong-Kai Xiao:1.Department of Cardiology, The Fourth Affiliated Hospital of Guangzhou Medical University, Zengcheng, Guangzhou, China. ;
期刊:The antihypertensive felodipine shows synergistic activity with immune checkpoint blockade and inhibits tumor growth via NFAT1 in LUSC
影响因子 :2.1
引用产品: SK-MES-1 细胞 , NCI-H226 [H226] 细胞
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FOXP family DNA methylation correlates with immune infiltration and prognostic value in NSCLC (2022-09-09)
作者:Dong-Mei Hu:1.Shandong Key Laboratory of Infectious Respiratory Diseases, Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China. ; 2.Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, China. ; Wen-Di Zhang:1.Shandong Key Laboratory of Infectious Respiratory Diseases, Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China. ; 2.Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, China. ; Zhuang-E Shi:1.Shandong Key Laboratory of Infectious Respiratory Diseases, Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, China. ; 2.Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, China. ; Meng-Yu Zhang:1.Shandong Key Laboratory of Infectious Respiratory Diseases, Department of Pulmonary and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan,
期刊:FOXP family DNA methylation correlates with immune infiltration and prognostic value in NSCLC
影响因子 :4.8
引用产品: BEAS-2B 细胞 , A549 [A-549] 细胞 , NCI-H1299 细胞 , PC-9 细胞 , NCI-H226 [H226] 细胞
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M7G-Related lncRNAs predict prognosis and regulate the immune microenvironment in lung squamous cell carcinoma (2022-11-04)
作者:Junfan Pan:1.Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, China. ; Zhidong Huang:1.The Second Surgical Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, 300060, China. ; Hancui Lin:1.Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, China. ; Wenfang Cheng:1.Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, China. ; Jinhuo Lai:1.Department of Medical Oncology, Fujian Medical University Union Hospital, Fuzhou, 350001, China. 571747377@qq.com. ; Jiancheng Li:1.Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, China. jianchengli_jack@126.com. ;
期刊:M7G-Related lncRNAs predict prognosis and regulate the immune microenvironment in lung squamous cell carcinoma
DOI:10.1186/s12885-022-10232-z
影响因子 :4.6
引用产品: NCI-H226 [H226] 细胞 , SK-MES-1 细胞 , BEAS-2B 细胞
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The Potential Mechanism of HDAC1-Catalyzed Histone Crotonylation of Caspase-1 in Nonsmall Cell Lung Cancer (2022-08-02)
作者:Chuan Jiang:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Jiangrong Liao:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Fang Yang:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Ting Jiang:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Dan Zhang:1.Department of Respiratory Medicine, Guizhou Aerospace Hospital, Zunyi, China. ; Yuanjun Xin:1.The Third Affiliated Hospital of Zunyi Medical University, Zunyi, China. ;
期刊:The Potential Mechanism of HDAC1-Catalyzed Histone Crotonylation of Caspase-1 in Nonsmall Cell Lung Cancer
影响因子 :2.7
引用产品: A549 [A-549] 细胞 , NCI-H1299 细胞 , NCI-H460 [H460] 细胞 , SK-MES-1 细胞 , NCI-H226 [H226] 细胞 , NCI-H661 细胞 , BEAS-2B 细胞 , 16HBE 细胞
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TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT (2011-01-20)
作者:Danjie Zhang:1.Department of Thoracic Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an 710004, China. ; Liangzhang Sun:1.Department of Thoracic Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an 710004, China. ; Jin Zhang:1.Department of Thoracic Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an 710004, China. Electronic address: zhangjin9605@163.com. ;
期刊:TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT
DOI:10.1016/j.taap.2021.115793
影响因子 :3.8
引用产品: BEAS-2B , A549 [A-549] 细胞 , NCI-H226 [H226] 细胞 , NCI-H520 细胞 , NCI-H1975 细胞
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Tambulin Targets Histone Deacetylase 1 Inhibiting Cell Growth and Inducing Apoptosis in Human Lung Squamous Cell Carcinoma (2008-00-20)
作者:Wuming Wang:1.Department of Thoracic Surgery, Jiangxi Provincial Chest Hospital, Nanchang, China. ; Yuzhen Liu:1.Department of Thoracic Surgery, Jiangxi Provincial Chest Hospital, Nanchang, China. ; Long Zhao:1.Department of Thoracic Surgery, Jiangxi Provincial Chest Hospital, Nanchang, China. ;
期刊:Tambulin Targets Histone Deacetylase 1 Inhibiting Cell Growth and Inducing Apoptosis in Human Lung Squamous Cell Carcinoma
影响因子 :5.6
引用产品: BEAS-2B , NCI-H226 [H226] 细胞 , NCI-H520 细胞
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