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产品概述
名称 | MM.1S (人多发性骨髓瘤细胞) (STR鉴定正确) |
别称 | MM.1S; MM1-S; MM-1S; MM1S |
种属 | 人 |
生长特性 | 半贴半悬 |
细胞形态 | 圆形细胞 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | The parent cell line, MM.1, was established from peripheral blood of a multiple myeloma patient who had become resistant to steroid-based therapy. The closely related cell line, MM.1R was also isolated from MM.1, but is resistant to dexamethasone. |
年龄(性别) | 女性;45岁 |
组织来源 | 外周血 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 骨髓瘤细胞 |
生物安全等级 | BSL-1 |
倍增时间 | 80 hours (PubMed=25984343) |
受体表达情况 | glucocorticoid receptor, expressed |
抗原表达情况 | CD25+, CD38+, CD52+, CD59+ |
基因表达情况 | lambda-light chain immunoglobulin |
保藏机构 | ATCC; CRL-2974 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 9,14 D2S1338 21,22 D3S1358 16,17 D5S818 8,12 D7S820 10,11 D8S1179 14 D13S317 13 D16S539 12 D18S51 11,16 D19S433 13 D21S11 29,30 FGA 20,24 PentaD 2.2,9 PentaE 13,15 TH01 7,8 TPOX 8 vWA 15,17 D6S1043 14,19 D12S391 17,24 D2S441 11 -
STR鉴定图
参考文献
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Synthesis and bioactivity evaluation of ferrocene-based hydroxamic acids as selective histone deacetylase 6 inhibitors(2022/12/07)
作者:Jiangkun Yan, Kairui Yue, Xuejing Fan
期刊:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1016/j.ejmech.2022.115004
影响因子 :6.700
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