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  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)

SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)

货号:CL-0208

规格:1×10⁶cells/T25培养瓶

价格: ¥1600

生长培养基:SH-SY5Y [SHSY-5Y] 细胞专用培养基

数量: - +

  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
  • SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)

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产品概述
产品信息
名称 SH-SY5Y [SHSY-5Y] (人神经母细胞瘤细胞) (STR鉴定正确)
别称 SHSY5Y; SHSY-5Y; SH-Sy5y; SK-SH-SY5Y; SY5Y
种属
生长特性 贴壁细胞,极少量悬浮
细胞形态 上皮细胞样
冻存条件 冻存液:90%FBS+10%DMSO 温度:液氮
培养方案A(默认)
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
推荐传代比例 1:3-1:8
推荐换液频率 2-3次/周
注意事项 1.该细胞容易聚团,传代第二天轻微聚团甚至漂浮为正常现象,无需换液继续培养2~3天后细胞可正常贴壁;2.细胞聚团严重影响细胞生长后,可用胰酶消化细胞使之重新分散,传代后少动少换液,聚团会有改善。
参考资料(来源文献)
背景描述 SH-SY5Y细胞是于1970年建自骨瘤转移灶的神经母细胞瘤SK-N-SH细胞系经3次克隆后的亚系(SK-N-SH→SH-SY→SH-SY5→SH-SY5Y)。SH-SY5Y细胞显示中等水平的多巴胺-β-羟基酶活性,SH-SY5Y细胞的饱和密度大于1×10^6/cm^2。
年龄(性别) 女性;4岁
组织来源 脑神经母细胞瘤,转移部位骨髓
细胞类型 肿瘤细胞
肿瘤类型 神经母细胞瘤细胞
生物安全等级 BSL-1
倍增时间 ~48-72 hours
抗原表达情况 Blood Type A; Rh+
保藏机构 ATCC; CRL-2266 DSMZ; ACC-209 ECACC; 94030304
STR鉴定
  • STR位点信息
    Amelogenin X
    CSF1PO 11
    D2S1338 17,19
    D3S1358 15,16
    D5S818 12
    D7S820 7,10
    D8S1179 15
    D13S317 11
    D16S539 8,13
    D18S51 13,16
    D19S433 13,14
    D21S11 31,31.2
    FGA 23.2,24
    PentaD 10,12
    PentaE 7,11
    TH01 7,10
    TPOX 8,11
    vWA 14,18
    D6S1043 12,18
    D12S391 18,22
    D2S441 11,11.3
  • STR鉴定图
参考文献
文献列表
  • Exosome Heterogeneity Affects the Distal “Barrier-Crossing” Trafficking of Exosome Encapsulated Quantum Dots (2024-02-23)

    作者:Di Wu:1.State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. ; 2.Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China. ; 3.School of Pharmacy, Zunyi Medical University, Zunyi 563003, China. ; Hang Sun:1.State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. ; 2.Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China. ; Bingwei Yang:1.State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. ; 2.Key Laboratory of Luminescence Analysi

    期刊:Exosome Heterogeneity Affects the Distal “Barrier-Crossing” Trafficking of Exosome Encapsulated Quantum Dots

    DOI:10.1021/acsnano.3c09378

    影响因子 :17.1

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基

  • An artificial protein modulator reprogramming neuronal protein functions (2024-03-06)

    作者:Peihua Lin:1.Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, School of Biomedical Engineering, National Center for Translational Medicine, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University, Shanghai, 200240, China. ; 2.Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. ; Bo Zhang:1.Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, School of Biomedical Engineering, National Center for Translational Medicine, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University, Shanghai, 200240, China. ; 2.World Laureates Association (WLA) Laboratories, Shanghai, 201210, China. ; Hongli Yang:1.Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. ; Shengfei Yang:1.Institute of Pharmaceutics, College of Pharmaceutical Scienc

    期刊:An artificial protein modulator reprogramming neuronal protein functions

    DOI:10.1038/s41467-024-46308-6

    影响因子 :16.6

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease (2024-01-24)

    作者:Jiefei Wang:1.Henan-Macquarie Uni Joint Centre for Biomedical Innovation, Academy for Advanced Interdisciplinary Studies, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan, 475004, China. ; Ping Shangguan:1.Henan-Macquarie Uni Joint Centre for Biomedical Innovation, Academy for Advanced Interdisciplinary Studies, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan, 475004, China. ; Xiaoyu Chen:1.School of Medical Technology, Beijing Institute of Technology, Beijing, China. ; Yong Zhong:1.Key Laboratory for Special Functional Materials of Ministry of Education, National & Local Joint Engineering Research Center for High-efficiency Display and Lighting Technology, School of Materials Science and Engineering, Collaborative Innovation Center of Nano Functional Materials and Applications, Henan University, Kaifeng, 475004, China. ; Ming Lin:1.Henan-Macquarie Un

    期刊:A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease

    DOI:10.1038/s41467-024-44737-x

    影响因子 :16.6

    引用产品: PC-12 (Undifferentiated) 细胞 ,  BV2 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞 ,  Neuro-2a [N2a; Neuro-2a] 细胞

  • SSK1-Loaded Neurotransmitter-Derived Nanoparticles for Alzheimer's Disease Therapy via Clearance of Senescent Cells (2024-03-01)

    作者:Wenbo Ji:1.Department of Neurology, Second Afffliated Hospital (Shanghai Changzheng Hospital) of Naval Medical University, Fengyang Road, Huangpu District, Shanghai, 200003, China. ; Honglei Zhou:1.Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, Changle Road, Qinhuai District, Nanjing, 210006, China. ; Wendanqi Liang:1.Department of Neurology, Second Afffliated Hospital (Shanghai Changzheng Hospital) of Naval Medical University, Fengyang Road, Huangpu District, Shanghai, 200003, China. ; 2.School of Health Science and Engineering, University of Shanghai for Science and Technology, Jungong Road, Yangpu District, Shanghai, 200093, China. ; Weicong Zhang:1.School of Pharmacy, University College London, Gower Street, London, W12 8LP, UK. ; Baofeng Gong:1.Department of Neurology, Second Afffliated Hospital (Shanghai Changzheng Hospital) of Naval Medical University, Fengyang Road, Huangpu District, Shanghai, 200003, China. ; Tong Yin:1.Depar

    期刊:SSK1-Loaded Neurotransmitter-Derived Nanoparticles for Alzheimer's Disease Therapy via Clearance of Senescent Cells

    DOI:10.1002/smll.202308574

    影响因子 :13.3

    引用产品: Neuro-2a [N2a; Neuro-2a] 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞

  • A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression (2024-02-27)

    作者:Yongrui Hai:1.Institute of Medical Research, Northwestern Polytechnical University, Xi'an 710072, China; Research & Development Institute of Northwestern Polytechnical University in Shenzhen, 518057, China. ; Renming Fan:1.Institute of Medical Research, Northwestern Polytechnical University, Xi'an 710072, China; Research & Development Institute of Northwestern Polytechnical University in Shenzhen, 518057, China. ; Ting Zhao:1.School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China. ; Ruizhuo Lin:1.Institute of Medical Research, Northwestern Polytechnical University, Xi'an 710072, China; Research & Development Institute of Northwestern Polytechnical University in Shenzhen, 518057, China. ; Junyan Zhuang:1.Institute of Medical Research, Northwestern Polytechnical University, Xi'an 710072, China; Research & Development Institute of Northwestern Polytechnical University in Shenzhen, 518057, China. ; Aohua Deng:1.Institute of Medical Research, N

    期刊:A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression

    DOI:10.1016/j.phrs.2024.107115

    影响因子 :9.3

    引用产品: B16-F10 细胞 ,  A-375 细胞 ,  4T1 细胞 ,  Renca [RenCa] 细胞 ,  GL261 细胞 ,  U-87 MG 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞 ,  U251 细胞

  • Modified acid polysaccharide derived from Salvia przewalskii with excellent wound healing and enhanced bioactivity (2024-01-30)

    作者:Kui Zhao:1.College of Material Science and Chemical Engineering, Southwest Forestry University, Kunming, Yunnan 650224, China. ; Cheng Qian:1.College of Material Science and Chemical Engineering, Southwest Forestry University, Kunming, Yunnan 650224, China. ; Luming Qi:1.School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China. ; Qing Li:1.School of Chemistry, Biology and Environment, Yuxi Normal University, Yuxi, Yunnan 651100, China. ; Can Zhao:1.State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy/School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, China. ; Jing Zhang:1.College of Chemcial Engineering and Technology, Taiyuan University of Science and Technology, Taiyuan, Shanxi 030024, China. ; Guiqi Han:1.State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy/School of Moder

    期刊:Modified acid polysaccharide derived from Salvia przewalskii with excellent wound healing and enhanced bioactivity

    DOI:10.1016/j.ijbiomac.2024.129803

    影响因子 :8.2

    引用产品: Hep G2 细胞 ,  MCF7 [MCF-7] 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞 ,  HT22 细胞

  • Cyfluthrin exposure during pregnancy causes neurotoxicity in offspring—Ca2+ overload via IP3R-GRP75-VDAC1 pathway (2024-03-15)

    作者:Haoxuan Gao:1.School of Public Health, Ningxia Medical University, No.1160, Shengli Street, Xingqing District, Yinchuan, Ningxia, China; Key Laboratory of Environmental Factors and Chronic Disease Control, No.1160, Shengli Street, Xingqing District, Yinchuan, Ningxia, China. ; Mi Tian:1.School of Public Health, Ningxia Medical University, No.1160, Shengli Street, Xingqing District, Yinchuan, Ningxia, China; Key Laboratory of Environmental Factors and Chronic Disease Control, No.1160, Shengli Street, Xingqing District, Yinchuan, Ningxia, China. ; Xiaozhe Geng:1.School of Public Health, Ningxia Medical University, No.1160, Shengli Street, Xingqing District, Yinchuan, Ningxia, China; Key Laboratory of Environmental Factors and Chronic Disease Control, No.1160, Shengli Street, Xingqing District, Yinchuan, Ningxia, China. ; Ji Zhao:1.School of Public Health, Ningxia Medical University, No.1160, Shengli Street, Xingqing District, Yinchuan, Ningxia, China; Key Laboratory of Environmental F

    期刊:Cyfluthrin exposure during pregnancy causes neurotoxicity in offspring—Ca2+ overload via IP3R-GRP75-VDAC1 pathway

    DOI:10.1016/j.ecoenv.2024.116218

    影响因子 :6.8

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Chemical Hypoxia Induces Pyroptosis in Neuronal Cells by Caspase-Dependent Gasdermin Activation (2024-02-11)

    作者:Chan Ho Park:1.Department of Anatomy, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju 26426, Republic of Korea. ; Jun Young Park:1.Department of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea. ; Won Gil Cho:1.Department of Anatomy, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju 26426, Republic of Korea. ;

    期刊:Chemical Hypoxia Induces Pyroptosis in Neuronal Cells by Caspase-Dependent Gasdermin Activation

    DOI:10.3390/ijms25042185

    影响因子 :5.6

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development (2024-03-01)

    作者:Shuaiguang Li:1.Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China. ; 2.Key Laboratory of Biopharmaceuticals, Postdoctoral Scientific Research Workstation, Shandong Academy of Pharmaceutical Sciences, Jinan, Shandong, China. ; 3.Shandong Provincial Key Laboratory for Rheumatic Disease and Translational Medicine, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China. ; Huarong Shao:1.Key Laboratory of Biopharmaceuticals, Postdoctoral Scientific Research Workstation, Shandong Academy of Pharmaceutical Sciences, Jinan, Shandong, China. ; Ting Sun:1.Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China. ; 2.Key Laboratory of Biopharmaceuticals, Postdoctoral Scientific Research Workstation, Shand

    期刊:Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development

    DOI:10.3389/fphar.2024.1366683

    影响因子 :5.6

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  BV2 细胞 ,  HT22 细胞

  • Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer’s Disease Models (2024-03-17)

    作者:Ruonan Wang:1.National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China. ; 2.School of Integrated Chinese and Western Medicine, Dalian Medical University, Dalian 116044, China. ; Shijia Kang:1.National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China. ; 2.School of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China. ; Zirui Zhao:1.National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian 116044, China. ; 2.School of Integrated Chinese and Western Medicine, Dalian Medical University, Dalian 116044, China. ; Lingling Jin:1.National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medica

    期刊:Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer’s Disease Models

    DOI:10.3390/ijms25063408

    影响因子 :5.6

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Libertellenone C attenuates oxidative stress and neuroinflammation with the capacity of NLRP3 inhibition (2024-02-26)

    作者:Jie Cao:1.Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ; Lanqin Li:1.Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. ; Runge Zhang:1.Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. ; Zhou Shu:1.Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ; Yaxin Zhang:1.Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. ; Weiguang Sun:1.Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong Un

    期刊:Libertellenone C attenuates oxidative stress and neuroinflammation with the capacity of NLRP3 inhibition

    DOI:10.1007/s13659-024-00438-y

    影响因子 :4.7

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  BV2 细胞

  • Potential Cause-and-Effect Relationship between Gut Microbiota and Childhood Neuroblastoma: A Mendelian Randomization Analysis (2024-03-27)

    作者:Jing Chu:1.Department of Pathology, Anhui Provincial Children's Hospital, 39 Wangjiang East Road, Hefei, Anhui, 230051, China. chujing198603@163.com. ;

    期刊:Potential Cause-and-Effect Relationship between Gut Microbiota and Childhood Neuroblastoma: A Mendelian Randomization Analysis

    DOI:10.1007/s12098-024-05065-6

    影响因子 :4.3

    引用产品: SK-N-BE (2) 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞

  • STAT4 targets KISS1 to inhibit the oxidative damage, inflammation and neuronal apoptosis in experimental PD models by inactivating the MAPK pathway (2024-02-08)

    作者:XiaoLei Zhang:1.Department of Neurology, Shanxi People's Hospital, Taiyuan 030012, China. Electronic address: zhangxl2011@yeah.net. ; Yu Wang:1.Department of Neurology, Fifth Hospital of Shanxi Medical University, Taiyuan 030012, China. ; Jia Lv:1.Department of Neurology, Fifth Hospital of Shanxi Medical University, Taiyuan 030012, China. ;

    期刊:STAT4 targets KISS1 to inhibit the oxidative damage, inflammation and neuronal apoptosis in experimental PD models by inactivating the MAPK pathway

    DOI:10.1016/j.neuint.2024.105683

    影响因子 :4.2

    引用产品: Hank's平衡盐溶液 (HBSS),含钙、镁,不含酚红 ,  SH-SY5Y [SHSY-5Y] 细胞

  • Corydaline alleviates Parkinson’s disease by regulating autophagy and GSK-3β phosphorylation (2024-01-30)

    作者:Kaikai Zhou:1.School of Energy and Intelligence Engineering, Henan University of Animal Husbandry and Economy, No. 6 Longzihu North Road, Zhengzhou City, 454000, People's Republic of China. kkz8868@hnuahe.edu.cn. ; Shasha Xu:1.the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. ;

    期刊:Corydaline alleviates Parkinson’s disease by regulating autophagy and GSK-3β phosphorylation

    DOI:10.1007/s00213-024-06536-6

    影响因子 :3.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Sinigrin improves cerebral ischaemia-reperfusion injury by inhibiting the TLR4 pathway-mediated oxidative stress (2024-02-18)

    作者:Shenglong Guo:1.Department II of Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, P.R. China. ; Qi Lei:1.Department II of Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, P.R. China. ; Qian Yang:1.Department II of Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, P.R. China. ; Ruili Chen:1.Department II of Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, P.R. China. ;

    期刊:Sinigrin improves cerebral ischaemia-reperfusion injury by inhibiting the TLR4 pathway-mediated oxidative stress

    DOI:10.1111/cbdd.14480

    影响因子 :3.0

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基

  • Thioredoxin-1 inhibits the activation of IRE1 by targeting Hsp90/p-Cdc37 chaperone complex in Parkinson disease (2023-07-10)

    作者:Xiansi Zeng:1.Research Center of Neuroscience, Jiaxing University Medical College, Jiaxing 314001, China. ; Wenshuo Geng:1.College of Life Sciences, Xinyang Normal University, Xinyang 464000, China. ; Yu Zhang:1.Research Center of Neuroscience, Jiaxing University Medical College, Jiaxing 314001, China. ; Jiayi Yin:1.Research Center of Neuroscience, Jiaxing University Medical College, Jiaxing 314001, China. ; Guangtao Xu:1.Department of Pathology, Institute of Forensic Science, Jiaxing University, Jiaxing 314001, China. ; Meng Yu:1.Research Center of Neuroscience, Jiaxing University Medical College, Jiaxing 314001, China. ; Li Li:1.Research Center of Neuroscience, Jiaxing University Medical College, Jiaxing 314001, China. ; Jinjing Jia:1.Research Center of Neuroscience, Jiaxing University Medical College, Jiaxing 314001, China. Electronic address: jiajinjing1986@126.com. ;

    期刊:Thioredoxin-1 inhibits the activation of IRE1 by targeting Hsp90/p-Cdc37 chaperone complex in Parkinson disease

    DOI:10.1016/j.arr.2023.102000

    影响因子 :13.1

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Bone marrow mesenchymal stem cells loaded into hydrogel/nanofiber composite scaffolds ameliorate ischemic brain injury (2023-01-28)

    作者:Yanhong Pei: 1.Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China;2.Program for Cancer and Cell Biology, Department of Human Anatomy, Histology and Embryology, PKU International Cancer Institute, MOE Key Laboratory of Carcinogenesis and Translational Research and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, 100191, China; Lifei Huang: 1.State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, China; Tong Wang: 1.State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, China; Qinhan Yao: 1.Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 1001

    期刊:Bone marrow mesenchymal stem cells loaded into hydrogel/nanofiber composite scaffolds ameliorate ischemic brain injury

    DOI:10.1016/j.mtadv.2023.100349

    影响因子 :10.0

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  SH-SY5Y [SHSY-5Y]细胞专用培养基 ,  PUMC-HUVEC-T1细胞专用培养基

  • MAPKAPK2, a potential dynamic network biomarker of α-synuclein prior to its aggregation in PD patients (2023-03-16)

    作者:Zhenggang Zhong:1.Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou, Guangdong, China. ; Jiabao Li:1.Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou, Guangdong, China. ; Jiayuan Zhong:1.School of Mathematics, South China University of Technology, Guangzhou, Guangdong, China. ; Yilin Huang:1.Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou, Guangdong, China. ; Jiaqi Hu:1.Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou, Guangdong, China. ; Piao Zhang:1.Department of Neurology, Guangdong Neuroscience Institute, Guangdong Provincial People's Hospital,

    期刊:MAPKAPK2, a potential dynamic network biomarker of α-synuclein prior to its aggregation in PD patients

    DOI:10.1038/s41531-023-00479-z

    影响因子 :8.7

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Controllable mitochondrial aggregation and fusion by a programmable DNA binder (2023-07-06)

    作者:Longyi Zhu:1.School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology Nanjing 210094 China kwren@njust.edu.cn. ; Yiting Shen:1.School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology Nanjing 210094 China kwren@njust.edu.cn. ; Shengyuan Deng:1.School of Environmental and Biological Engineering, Nanjing University of Science and Technology Nanjing 210094 China. ; Ying Wan:1.Intelligent Microsystem Technology and Engineering Center, School of Mechanical Engineering, Nanjing University of Science and Technology Nanjing 210094 China wanying@njust.edu.cn. ; Jun Luo:1.School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology Nanjing 210094 China kwren@njust.edu.cn. ; Yan Su:1.Intelligent Microsystem Technology and Engineering Center, School of Mechanical Engineering, Nanjing University of Science and Technology Nanjing 210094 China wanying@njust.edu.cn. ; Mingxu You:1.Department of Chem

    期刊:Controllable mitochondrial aggregation and fusion by a programmable DNA binder

    DOI:10.1039/D2SC07095B

    影响因子 :8.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  4T1 细胞

  • NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells (2023-11-18)

    作者:Caixia Zhang:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; Bo Jiao:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; Xueqin Cao:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; Wencui Zhang:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; Shangchen Yu:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; Kaiwen Zhang:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ;

    期刊:NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells

    DOI:10.1016/j.biopha.2023.115889

    影响因子 :7.5

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基 ,  青霉素-链霉素溶液 (双抗),100×

  • Nanosensor-Driven Detection of Neuron-Derived Exosomal Aβ42 with Graphene Electrolyte-Gated Transistor for Alzheimer’s Disease Diagnosis (2023-03-21)

    作者:Jiahao Li:1.School of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan 430065, P. R. China. ; Wei Ni:1.School of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan 430065, P. R. China. ; 2.Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430061, China. ; Dan Jin:1.School of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan 430065, P. R. China. ; Yi Yu:1.School of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan 430065, P. R. China. ; Meng-Meng Xiao:1.Key Laboratory for the Physics and Chemistry of Nanodevices and Center for Carbon-based Electronics, School of Electronics, Peking University, Beijing 100871, P. R. China. ; Zhi-Yong Zhang:1.Key Laboratory for the Physics and Chemistry of Nanodevices and Center for Carbon-based Electronics, School of Electronics, Peking University, Beijing 100871, P

    期刊:Nanosensor-Driven Detection of Neuron-Derived Exosomal Aβ42 with Graphene Electrolyte-Gated Transistor for Alzheimer’s Disease Diagnosis

    DOI:10.1021/acs.analchem.2c05751

    影响因子 :7.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  SH-SY5Y [SHSY-5Y]细胞专用培养基

  • Combined exposure to manganese and iron decreases oxidative stress-induced nerve damage by increasing Nrf2/HO-1/NQO1 expression (2023-12-20)

    作者:Yuan-Yuan Fang:1.Department of Toxicology, School of Public Health, Guangxi Medical University, Nanning 530021, China; Key Laboratory of Prevention and Control of Highly Prevalent Diseases in Guangxi Colleges and Universities, Medical University of Guangxi, Nanning 530021, China. ; Meng-Jun Teng:1.Department of Toxicology, School of Public Health, Guangxi Medical University, Nanning 530021, China; Key Laboratory of Prevention and Control of Highly Prevalent Diseases in Guangxi Colleges and Universities, Medical University of Guangxi, Nanning 530021, China. ; Jian-Chao Peng:1.Department of Toxicology, School of Public Health, Guangxi Medical University, Nanning 530021, China; Key Laboratory of Prevention and Control of Highly Prevalent Diseases in Guangxi Colleges and Universities, Medical University of Guangxi, Nanning 530021, China. ; Xiao-Wei Zheng:1.Department of Toxicology, School of Public Health, Guangxi Medical University, Nanning 530021, China; Key Laboratory of Prevention a

    期刊:Combined exposure to manganese and iron decreases oxidative stress-induced nerve damage by increasing Nrf2/HO-1/NQO1 expression

    DOI:10.1016/j.ecoenv.2023.115853

    影响因子 :6.8

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Tri-element nanozyme PtCuSe as an ingenious cascade catalytic machine for the amelioration of Parkinson’s disease-like symptoms (2023-05-30)

    作者:Hongdang Xu:1.Department of Anesthesiology, Henan Provincial People's Hospital, People's Hospital of Henan University, Central China Fuwai Hospital, Central China Fuwai Hospital of Zhengzhou University, Zhengzhou, Henan, China. ; Xin Ding:1.Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. ; Lingrui Li:1.The Application Center for Precision Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. ; Qing Li:1.The Application Center for Precision Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. ; Zhiye Li:1.The Application Center for Precision Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. ; Hongqi Lin:1.Department of Anesthesiology, Henan Provincial People's Hospital, People's Hospital of Henan University, Central China Fuwai Hospital, Central China Fuwai Hospital of Zheng

    期刊:Tri-element nanozyme PtCuSe as an ingenious cascade catalytic machine for the amelioration of Parkinson’s disease-like symptoms

    DOI:10.3389/fbioe.2023.1208693

    影响因子 :5.7

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • α-Synuclein Induces Neuroinflammation Injury through the IL6ST-AS/STAT3/HIF-1α Axis (2023-01-11)

    作者:Danyu Lin:1.Department of Neurology, The Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510080, China. ; 2.Department of Neurology, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen 518033, China. ; Han Zhang:1.Department of Neurology, The Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510080, China. ; 2.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China. ; Jieli Zhang:1.Department of Neurology, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen 518033, China. ; Kaixun Huang:1.Department of Neurology, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen 518033, China. ; Ying Chen:1.Department of Neurology, The Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510080, China. ; 2.Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen M

    期刊:α-Synuclein Induces Neuroinflammation Injury through the IL6ST-AS/STAT3/HIF-1α Axis

    DOI:10.3390/ijms24021436

    影响因子 :5.6

    引用产品: HMC3 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞

  • The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model (2023-02-13)

    作者:Ruru Jia:1.Laboratory of Hypoxic Biomedicine, Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, 9 Seyuan Road, Nantong 226019, China. ; Yanling Liu:1.Laboratory of Hypoxic Biomedicine, Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, 9 Seyuan Road, Nantong 226019, China. ; Ke Shuai:1.Laboratory of Hypoxic Biomedicine, Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, 9 Seyuan Road, Nantong 226019, China. ; Cheng Zhou:1.Laboratory of Hypoxic Biomedicine, Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, 9 Seyuan Road, Nantong 226019, China. ; Lei Chen:1.Laboratory of Hypoxic Biomedicine, Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, 9 Seyuan Road, Nantong 226019, China. ; Li Zhu:1.Laboratory

    期刊:The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model

    DOI:10.3390/ijms24043709

    影响因子 :5.6

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Fabrication of P and N Co-Doped Carbon Dots for Fe3+ Detection in Serum and Lysosomal Tracking in Living Cells (2023-02-05)

    作者:Yanzhi Xing:1.Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China. ; Mei Yang:1.School of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116029, China. ; Xuwei Chen:1.Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China. ;

    期刊:Fabrication of P and N Co-Doped Carbon Dots for Fe3+ Detection in Serum and Lysosomal Tracking in Living Cells

    DOI:10.3390/bios13020230

    影响因子 :5.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  Hela 细胞

  • Huannao Yicong decoction ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by interfering with neurotoxic interaction of Aβ-tau (2023-08-01)

    作者:Huiqin Zhang:1.Institute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, 1 Xiyuan Caochang Road, Haidian District, Beijing, 100091, China. ; Wenxuan Chen:1.Institute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, 1 Xiyuan Caochang Road, Haidian District, Beijing, 100091, China. ; Zehui Li:1.Institute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, 1 Xiyuan Caochang Road, Haidian District, Beijing, 100091, China. ; Qiaoyi Huang:1.School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, No. 11 North Third Ring Road East, Chaoyang District, Beijing, 100029, China. ; Jiayu Wen:1.School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, No. 11 North Third Ring Road East, Chaoyang District, Beijing, 100029, China. ; Surui Chang:1.Institute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, 1 Xiyuan Caochang Road, Haidian District, Beijing

    期刊:Huannao Yicong decoction ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by interfering with neurotoxic interaction of Aβ-tau

    DOI:10.1016/j.jep.2023.116985

    影响因子 :5.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Novel flavonoid 1,3,4-oxadiazole derivatives ameliorate MPTP-induced Parkinson's disease via Nrf2/NF-κB signaling pathway (2023-06-03)

    作者:Hua-Wen Meng:1.Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, College of Food and Biological Engineering, Hefei University of Technology, Hefei, China. ; Zhen-Bao Shen:1.Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, College of Food and Biological Engineering, Hefei University of Technology, Hefei, China. ; Xian-She Meng:1.Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, College of Food and Biological Engineering, Hefei University of Technology, Hefei, China. ; Leng-Wei:1.Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, College of Food and Biological Engineering, Hefei University of Technology, Hefei, China. ; Ze-Qun Yin:1.Department of Cardiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, H

    期刊:Novel flavonoid 1,3,4-oxadiazole derivatives ameliorate MPTP-induced Parkinson's disease via Nrf2/NF-κB signaling pathway

    DOI:10.1016/j.bioorg.2023.106654

    影响因子 :5.1

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Neuroprotective effect of chlorogenic acid on Parkinson's disease like symptoms through boosting the autophagy in zebrafish (2023-08-05)

    作者:Xin Gao:1.Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), 28789 East Jingshi Road, Ji'nan, 250103, Shandong Province, PR China; Key Laboratory for Drug Screening Technology of Shandong Academy of Sciences, 28789 East Jingshi Road, Ji'nan, 250103, Shandong Province, PR China. ; Baoyue Zhang:1.Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), 28789 East Jingshi Road, Ji'nan, 250103, Shandong Province, PR China; Key Laboratory for Drug Screening Technology of Shandong Academy of Sciences, 28789 East Jingshi Road, Ji'nan, 250103, Shandong Province, PR China. ; Yuanteng Zheng:1.Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), 28789 East Jingshi Road, Ji'nan, 250103, Shandong Province, PR China; Key Laboratory for Drug Screening Technology of Shandong Academy of Sciences, 28789 East Jingshi Road, Ji'nan, 250103, Shandong Province, PR China. ; Xuchang Liu:1.Biology Institute, Qilu University of

    期刊:Neuroprotective effect of chlorogenic acid on Parkinson's disease like symptoms through boosting the autophagy in zebrafish

    DOI:10.1016/j.ejphar.2023.175950

    影响因子 :5.0

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Identifying the potential genes in alpha synuclein driving ferroptosis of Parkinson’s disease (2023-10-06)

    作者:Min Wang:1.Department of Neurology, Shanxi Cardiovascular Hospital/Cardiovascular Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China. wangmin4325@126.com. ; Taole Li:1.Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China. ; Rong Gao:1.Department of Neurology, Shanxi Cardiovascular Hospital/Cardiovascular Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China. ; Yu Zhang:1.Hunan Key Laboratory of Pharmacogenetics, Department of Clinical Pharmacology, Institute of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan, China. ; Yanqing Han:1.Department of Neurology, Shanxi Cardiovascular Hospital/Cardiovascular Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China. ;

    期刊:Identifying the potential genes in alpha synuclein driving ferroptosis of Parkinson’s disease

    DOI:10.1038/s41598-023-44124-4

    影响因子 :4.6

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM 培养基

  • VCAM-1+ hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis (2023-06-19)

    作者:Xiao Zhang:1.Department of Neurology, The Second Hospital of Shandong University, Jinan, 250033, China. ; Xiaoyu Sang:1.Department of Neurology, The Second Hospital of Shandong University, Jinan, 250033, China. ; Yanting Chen:1.Department of Neurology, The Second Hospital of Shandong University, Jinan, 250033, China. ; Hao Yu:1.School of Medicine, Nankai University, Tianjin, 300071, China. ; Yuan Sun:1.The Second Hospital of Shandong University, Jinan, 250033, China. ; Xilong Liang:1.Department of Biostatistics, School of Public Health, Yale University, 38 Crown Street, APT 203, New Haven, CT, 06510, USA. ; Xiaolei Zheng:1.Department of Neurology, The Second Hospital of Shandong University, Jinan, 250033, China. ; Xiao Wang:1.Department of Neurology, The Second Hospital of Shandong University, Jinan, 250033, China. ; Hui Yang:1.Department of Neurology, The Second Hospital of Shandong University, Jinan, 250033, China. ; Jianzhong Bi:1.Department of Neurology, The Second Hospita

    期刊:VCAM-1+ hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis

    DOI:10.1007/s11064-023-03968-y

    影响因子 :4.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基

  • EIF5A2 specifically regulates the transcription of aging-related genes in human neuroblastoma cells (2023-02-07)

    作者:Yuwei Liu:1.Department of Internal Medicine and Geriatrics, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei, China. ; 2.Department of General Practice, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei, China. ; Li Peng:1.Department of Internal Medicine and Geriatrics, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei, China. ; 2.Department of Cardiology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei, China. ; Jing Chen:1.Department of Internal Medicine and Geriatrics, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei, China. ; Ling Chen:1.Department of Internal Medicine and Geriatrics, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei, China. ; Ying Wu:1.Department of Internal Medicine and Geriatrics, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei, China. ; Mengxin Cheng:1.Department of Internal Medicine and Geriatrics, Zhongnan Hosp

    期刊:EIF5A2 specifically regulates the transcription of aging-related genes in human neuroblastoma cells

    DOI:10.1186/s12877-023-03793-6

    影响因子 :4.1

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Exploring the Therapeutic Effects of Multifunctional N-Salicylic Acid Tryptamine Derivative against Parkinson’s Disease (2023-07-28)

    作者:Xuelin Li:1.School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China. ; 2.The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China. ; Shuzhi Wang:1.School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China. ; Shan Duan:1.The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China. ; Lin Long:1.School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China. ; Linsheng Zhuo:1.School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China. ; Yan Peng:1.School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China. ; Yongxia Xiong:1.School of Pharmaceutical Science, Hengyang Medical School, University of

    期刊:Exploring the Therapeutic Effects of Multifunctional N-Salicylic Acid Tryptamine Derivative against Parkinson’s Disease

    DOI:10.1021/acsomega.3c04277

    影响因子 :4.1

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  HMC3 细胞

  • S1PR2 Regulates Autophagy Through the AKT/mTOR Pathway to Promote Pathological Damage in Alzheimer’s Disease (2023-11-22)

    作者:Xiaoping Wang:1.Department of Neurology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Sichuan, China. ; Rui Huang:1.Department of Neurology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Sichuan, China. ; Bin Huang:1.Department of Neurology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Sichuan, China. ; Xiaojia Li:1.Department of Neurology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Sichuan, China. ;

    期刊:S1PR2 Regulates Autophagy Through the AKT/mTOR Pathway to Promote Pathological Damage in Alzheimer’s Disease

    DOI:10.3233/JAD-230533

    影响因子 :4.0

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基

  • Inhibition of Astrocytic Carbohydrate Sulfotransferase 15 Promotes Nerve Repair After Spinal Cord Injury via Mitigation of CSPG Mediated Axonal Inhibition (2023-03-13)

    作者:Liming Li:1.Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266071, China. liming_8911@163.com. ; 2.Rehabilitation Sciences and Engineering, University of Health and Rehabilitation Sciences, Qingdao, 266071, China. liming_8911@163.com. ; Heping Zheng:1.Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266071, China. ; Xuepei Ma:1.Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266071, China. ; Jie Bai:1.Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266071, China. ; Shumin Ma:1.Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266071, China. ; Zhuoyue Li:1.Key Laboratory

    期刊:Inhibition of Astrocytic Carbohydrate Sulfotransferase 15 Promotes Nerve Repair After Spinal Cord Injury via Mitigation of CSPG Mediated Axonal Inhibition

    DOI:10.1007/s10571-023-01333-9

    影响因子 :4.0

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基 ,  DMEM高糖 培养基

  • Morphine induces HADHA succinylation, while HADHA desuccinylation alleviates morphine tolerance by influencing autophagy (2023-09-09)

    作者:Yuanxin Huang:1.Department of Pain, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China. ; Sihui Lu:1.School of Anesthesiology, Guizhou Medical University, Guiyang, Guizhou, China. ; Yu Chen:1.Department of Pain, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China. ; 2.School of Basic Medicine, School of Pharmacy, Guizhou Medical University, Guiyang, Guizhou, China. ; Yuanyu Feng:1.Department of Anesthesiology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China. ; Wei Lu:1.Department of Pain, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China. luwei@gmc.edu.cn. ; 2.School of Anesthesiology, Guizhou Medical University, Guiyang, Guizhou, China. luwei@gmc.edu.cn. ;

    期刊:Morphine induces HADHA succinylation, while HADHA desuccinylation alleviates morphine tolerance by influencing autophagy

    DOI:10.1007/s00210-023-02697-x

    影响因子 :3.6

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Insufficient autophagy enables the nuclear factor erythroid 2-related factor 2 (NRF2) to promote ferroptosis in morphine-treated SH-SY5Y cells (2023-12-05)

    作者:Xin Huang:1.College of Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, People's Republic of China. ; Xinyue Yan:1.College of Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, People's Republic of China. ; Gang Chen:1.Department of Forensic Medicine, School of Basic Medical Science, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, People's Republic of China. ; Yue Feng:1.College of Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, People's Republic of China. ; Yuying Bai:1.College of Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, People's Republic of China. ; Peng Yan:1.College of Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, People's Republic of China. ; Jianghua Lai:1.College of Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, People's Republic of China. ; Shuguang Wei:1.College of Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061,

    期刊:Insufficient autophagy enables the nuclear factor erythroid 2-related factor 2 (NRF2) to promote ferroptosis in morphine-treated SH-SY5Y cells

    DOI:10.1007/s00213-023-06485-6

    影响因子 :3.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • miR-15b-5p transcription mediated by CREB1 protects against inflammation and apoptosis in Parkinson disease models by inhibiting AXIN2 and activating Wnt/β-catenin (2023-11-07)

    作者:Tianyi Liu:1.Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China. ; Guozhong Li:1.Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China. ; 2.Department of Neurology, Heilongjiang Provincial Hospital, Harbin, Heilongjiang 150000, P.R. China. ;

    期刊:miR-15b-5p transcription mediated by CREB1 protects against inflammation and apoptosis in Parkinson disease models by inhibiting AXIN2 and activating Wnt/β-catenin

    DOI:10.1093/jnen/nlad084

    影响因子 :3.2

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  293T [HEK-293T] 细胞

  • METTL3 relieved the injury of SH-SY5Y cells treated with lipopolysaccharide and exposed to sevoflurane through regulating the m6A levels of Sox2 (2023-03-28)

    作者:Yilong Wang:1.Department of Anesthesiology, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; 2.Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China. ; 3.Shanghai Municipal Key Clinical Specialty, Shanghai, China. ; Zeyong Yang:1.Department of Anesthesiology, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ; 2.Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China. ; 3.Shanghai Municipal Key Clinical Specialty, Shanghai, China. ;

    期刊:METTL3 relieved the injury of SH-SY5Y cells treated with lipopolysaccharide and exposed to sevoflurane through regulating the m6A levels of Sox2

    DOI:10.1002/brb3.2936

    影响因子 :3.1

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Protective effect of cornuside on OGD/R injury in SH-SY5Y cells and its underlying mechanism (2023-09-16)

    作者:Xinyu Wang:1.Department of Rehabilitation Medicine, Binzhou Medical University, Yantai 264003, PR China; Department of Rehabilitation Medicine, Shengli Oilfield Central Hospital, Dongying 257097, PR China. Electronic address: 1845233003@qq.com. ; Chao Yan:1.Department of Rehabilitation Medicine, Binzhou Medical University, Yantai 264003, PR China. Electronic address: yanchao99@yeah.net. ; Chaoyun Wang:1.Department of Pharmacology, Binzhou Medical University, Yantai, 264003, PR China. Electronic address: ytwcy@126.com. ; Xiaoyan Xu:1.Department of Immunology, Binzhou Medical University, Yantai, 264003, PR China. Electronic address: xuxiaoyanhappy@163.com. ; Zhihao Liu:1.Department of Rehabilitation Medicine, Binzhou Medical University, Yantai 264003, PR China. Electronic address: hzly594959@163.com. ; Xin Wang:1.Department of Rehabilitation Medicine, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu 225009, PR China. Electronic address: wx000805qm@yeah.net. ; Jianwe

    期刊:Protective effect of cornuside on OGD/R injury in SH-SY5Y cells and its underlying mechanism

    DOI:10.1016/j.brainres.2023.148585

    影响因子 :2.9

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  青霉素-链霉素溶液 (双抗),100× ,  DMEM无糖 培养基

  • Study on Calceolarioside A Anti-Aβ25–35-Induced Damage in SH-SY5Y cells by Atomic Force Microscopy (2023-05-11)

    作者:Yujuan Chen:1.School of Life Sciences, Changchun University of Science and Technology, Changchun, 130022, China. ; 2.International Research Center for Nano Handling and Manufacturing of China, Changchun University of Science and Technology, Changchun, 130022, China. ; 3.Ministry of Education Key Laboratory for Cross-Scale Micro and Nano Manufacturing, Changchun University of Science and Technology, Changchun, 130022, China. ; Kaige Qu:1.International Research Center for Nano Handling and Manufacturing of China, Changchun University of Science and Technology, Changchun, 130022, China. ; 2.Ministry of Education Key Laboratory for Cross-Scale Micro and Nano Manufacturing, Changchun University of Science and Technology, Changchun, 130022, China. ; Ying Wang:1.International Research Center for Nano Handling and Manufacturing of China, Changchun University of Science and Technology, Changchun, 130022, China. ; 2.Ministry of Education Key Laboratory for Cross-Scale Micro and Nano Manufactur

    期刊:Study on Calceolarioside A Anti-Aβ25–35-Induced Damage in SH-SY5Y cells by Atomic Force Microscopy

    DOI:10.1002/cbdv.202300430

    影响因子 :2.9

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Silencing of purinergic receptor P2Y2 inhibited enteric neural crest cell proliferation, invasion and migration via suppressing ERK signaling pathway in Hirschsprung disease (2023-08-23)

    作者:Dengrui Liu:1.Department of Pediatric Surgery, The First Hospital of Lanzhou University, No. 1 Donggang West Road, Lanzhou, 730000 Gansu China. ; Hongxia Kang:1.Department of Pain, Gansu Provincial People's Hospital, Lanzhou, 730000 Gansu China. ; Mingtai Gao:1.Department of Pediatric Surgery, The First Hospital of Lanzhou University, No. 1 Donggang West Road, Lanzhou, 730000 Gansu China. ; Wei Pei:1.Department of Pediatric Surgery, The First Hospital of Lanzhou University, No. 1 Donggang West Road, Lanzhou, 730000 Gansu China. ; Shimo Wang:1.Department of Pediatric Surgery, The First Hospital of Lanzhou University, No. 1 Donggang West Road, Lanzhou, 730000 Gansu China. ; Zhou Chen:1.Department of Pediatric Surgery, The First Hospital of Lanzhou University, No. 1 Donggang West Road, Lanzhou, 730000 Gansu China. ;

    期刊:Silencing of purinergic receptor P2Y2 inhibited enteric neural crest cell proliferation, invasion and migration via suppressing ERK signaling pathway in Hirschsprung disease

    DOI:10.1007/s13205-023-03721-w

    影响因子 :2.8

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Transcriptomics reveals the effects of NTRK1 on endoplasmic reticulum stress response-associated genes in human neuronal cell lines (2023-04-12)

    作者:Bo Jiao:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; Mi Zhang:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; 2.Department of Anesthesiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei Province, China. ; Caixia Zhang:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; Xueqin Cao:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; Baowen Liu:1.Department of Anesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. ; Ningbo Li:1.Department of Anesthesiology, Tongji Hospital of Tongji Medi

    期刊:Transcriptomics reveals the effects of NTRK1 on endoplasmic reticulum stress response-associated genes in human neuronal cell lines

    DOI:10.7717/peerj.15219

    影响因子 :2.7

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基

  • Benzo(a)pyrene-induced mitochondrial respiration and glycolysis disturbance in human neuroblastoma cells (2023-02-01)

    作者:Yi Lyu:1.Department of Toxicology, School of Public Health, Shanxi Medical University, China. ; Jin Yang:1.Department of Toxicology, School of Public Health, Shanxi Medical University, China. ; LiXia Cheng:1.Department of Toxicology, School of Public Health, Shanxi Medical University, China. ; ZhaoFei Li:1.Department of Toxicology, School of Public Health, Shanxi Medical University, China. ; JinPing Zheng:1.Department of Toxicology, School of Public Health, Shanxi Medical University, China. ; 2.Collaborative Innovation Center for Aging Mechanism Research and Transformation, Center for Healthy Aging, Changzhi Medical College, China. ;

    期刊:Benzo(a)pyrene-induced mitochondrial respiration and glycolysis disturbance in human neuroblastoma cells

    DOI:10.2131/jts.48.87

    影响因子 :2.0

    引用产品: MEM/F12 培养基 ,  特级胎牛血清 ,  SH-SY5Y [SHSY-5Y] 细胞

  • The Diagnostic Model of Ligusticum Chuanxiong Hort. Against Cerebral Stroke Using Network Pharmacology and Transcriptomics Analyses (2023-10-23)

    作者:Jinfeng Zhang:1.Department of Rehabilitation Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310000 Hangzhou, Zhejiang, China. ; Chongyin Cai:1.Department of Pharmacy, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310000 Hangzhou, Zhejiang, China. ; Ying Luo:1.Department of Pharmacy, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310000 Hangzhou, Zhejiang, China. ; Yan Wu:1.Department of Rehabilitation Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310000 Hangzhou, Zhejiang, China. ; Fanghui Qiu:1.Department of Rehabilitation Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310000 Hangzhou, Zhejiang, China. ;

    期刊:The Diagnostic Model of Ligusticum Chuanxiong Hort. Against Cerebral Stroke Using Network Pharmacology and Transcriptomics Analyses

    DOI:10.31083/j.jin2206149

    影响因子 :1.8

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Effect of 4-AP on MPP+/ MPTP-induced Parkinson's disease model (2023-08-31)

    作者:Qiongwen Rong:1.Department of Neurology, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, 570102, China. 13907580113@163.com. ; Chang Zhou:1.Department of Neurology, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, 570102, China. 13907580113@163.com. ; Yuanyuan Ma:1.Department of Neurology, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, 570102, China. 13907580113@163.com. ;

    期刊:Effect of 4-AP on MPP+/ MPTP-induced Parkinson's disease model

    DOI:10.14715/cmb/2023.69.8.10

    影响因子 :1.6

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • MicroRNA-375-3p Alleviates Salicylate-Induced Neuronal Injury by Targeting ELAVL4 in Tinnitus (2023-03-20)

    作者:Department of ENT, The First Affiliated Hospital of Yangtze University, Jingzhou, China; Department of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Cardiovascular, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China

    期刊:MicroRNA-375-3p Alleviates Salicylate-Induced Neuronal Injury by Targeting ELAVL4 in Tinnitus

    DOI:10.1055/s-0043-1764379

    影响因子 :0.9

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基

  • Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides (2022-08-06)

    作者:Zhanchi Zhu:1.School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei, China. ; 2.CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano Bionics, Chinese Academy of Sciences, Suzhou, China. ; Yuanxin Zhai:1.School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei, China. ; 2.CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano Bionics, Chinese Academy of Sciences, Suzhou, China. ; Ying Hao:1.School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei, China. ; 2.CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano Bionics, Chinese Academy of Sciences, Suzhou, China. ; 3.Guangdong Institute of Semiconductor Micro-Nano Manufacturing Technology, Guangdong, China. ; Quanwei Wang:1.CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano Bionics, Chinese Academy of Sciences, Suzhou, Ch

    期刊:Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides

    DOI:10.1002/jev2.12255

    影响因子 :17.3

    引用产品: bEnd.3 [BEND3] 细胞 ,  U-87 MG 细胞 ,  293T [HEK-293T] 细胞 ,  A549 [A-549] 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞 ,  Hep G2 细胞

  • NIR-II light-activated two-photon squaric acid dye with Type I photodynamics for antitumor therapy (2022-10-24)

    作者:Kexin Wang: 1.Key Laboratory of Optoelectronic Devices and Systems of Guangdong Province & Ministry of Education, College of Physics and Optoelectronic Engineering Shenzhen University, Shenzhen, Guangdong Province, 518060, P. R. China; Yunjian Xu: 1.Key Laboratory of Optoelectronic Devices and Systems of Guangdong Province & Ministry of Education, College of Physics and Optoelectronic Engineering Shenzhen University, Shenzhen, Guangdong Province, 518060, P. R. China; Zhenjiang Chen: 1.Key Laboratory of Optoelectronic Devices and Systems of Guangdong Province & Ministry of Education, College of Physics and Optoelectronic Engineering Shenzhen University, Shenzhen, Guangdong Province, 518060, P. R. China; Huixian Li: 1.Key Laboratory of Optoelectronic Devices and Systems of Guangdong Province & Ministry of Education, College of Physics and Optoelectronic Engineering Shenzhen University, Shenzhen, Guangdong Province, 518060, P. R. China; Rui Hu: 1.Key Laboratory of Optoelectronic Devices a

    期刊:NIR-II light-activated two-photon squaric acid dye with Type I photodynamics for antitumor therapy

    DOI:10.1515/nanoph-2022-0482

    影响因子 :7.9

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  DMEM高糖 培养基

  • Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells (2022-12-09)

    作者:CanCan Guo:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; Yi Lyu:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China; Department of Biochemistry and Molecular Biology, School of Preclinical Medicine in Shanxi Medical University, Taiyuan 030001, China. ; ShuangShuang Xia:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; XueKe Ren:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; ZhaoFei Li:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; FengJie Tian:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; JinPing Zheng:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiy

    期刊:Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells

    DOI:10.1016/j.ecoenv.2022.114350

    影响因子 :7.1

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基 ,  特级胎牛血清

  • Chebulic Acid Prevents Hypoxia Insult via Nrf2/ARE Pathway in Ischemic Stroke (2022-12-19)

    作者:Rong Zhou:1.Wuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China. ; Kuan Lin:1.Wuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China. ; 2.Institute of Cerebrovascular Disease, Jianghan University, Wuhan 430056, China. ; Changlong Leng:1.Wuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China. ; 2.Institute of Cerebrovascular Disease, Jianghan University, Wuhan 430056, China. ; Mei Zhou:1.Wuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China. ; Jing Zhang:1.Wuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China. ; Youwei Li:1.Wuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China. ; Yujing Liu:1.Wuhan Institutes of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, China. ; X

    期刊:Chebulic Acid Prevents Hypoxia Insult via Nrf2/ARE Pathway in Ischemic Stroke

    DOI:10.3390/nu14245390

    影响因子 :6.7

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • LncRNA TUG1 compromised neuronal mitophagy in cerebral ischemia/reperfusion injury by targeting sirtuin 1 (2003-02-20)

    作者:Long-Xing Xue:1.Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No. 1 JianShe Road, Zhengzhou, 450052, Henan Province, People's Republic of China. ; Song-Feng Chen:1.Department of Orthopaedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ; Shi-Xing Xue:1.Department of Neurology, Affiliated Xinhua Hospital of Dalian University, Dalian, 116021, China. ; Pei-Dong Liu:1.Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA. ; 2.Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, People's Republic of China. ; Hong-Bo Liu:1.Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No. 1 JianShe Road, Zhengzhou, 450052, Henan Province, People's Republic of China. hongbo_liuqq@yeah.net. ;

    期刊:LncRNA TUG1 compromised neuronal mitophagy in cerebral ischemia/reperfusion injury by targeting sirtuin 1

    DOI:10.1007/s10565-022-09700-w

    影响因子 :6.1

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells (2022-08-17)

    作者:Hai-Qun Dong:1.Department of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, P.R. China. ; Shi-Jing Liang:1.Department of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, P.R. China. ; Yu-Ling Xu:1.Department of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, P.R. China. ; Yi Dai:1.Department of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, P.R. China. ; Na Sun:1.Department of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, P.R. China. ; Dong-Hong Deng:1.Department of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, P.R. China. ; Peng Che

    期刊:Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells

    DOI:10.3892/ijo.2022.5409

    影响因子 :5.9

    引用产品: K-562 [K562] 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞

  • Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop (2004-02-20)

    作者:Hengfang Tang:1.Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China. ; 2.Science Island Branch of Graduate, University of Science and Technology of China, Hefei 230026, China. ; Zhiming Zheng:1.Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China. ; Han Wang:1.Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China. ; 2.Anhui Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China. ; Li Wang:1.Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China. ; Genhai Zhao:1.Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China. ; Peng Wang:1.Anhui Key

    期刊:Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop

    DOI:10.3390/nu14071504

    影响因子 :5.9

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Silencing of long chain noncoding RNA paternally expressed gene (PEG10) inhibits the progression of neuroblastoma by regulating microRNA-449a (miR-449a)/ribosomal protein S2 (RPS2) axis (2002-02-20)

    作者:Jian Zhang:1.Department of Geriatrics, Qingdao Chengyang District People's Hospital, Qingdao, Shandong, P.R. China. ; Wei Liu:1.Department of Health Management, Qingdao Eighth People's Hospital, Qingdao, Shandong, P.R. China. ; Ping Ji:1.Department of Ophthalmology, Qingdao Eighth People's Hospital, Qingdao, Shandong, P.R. China. ; Yan Zhang:1.The Third Department of Internal Medicine, Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong, P.R. China. ;

    期刊:Silencing of long chain noncoding RNA paternally expressed gene (PEG10) inhibits the progression of neuroblastoma by regulating microRNA-449a (miR-449a)/ribosomal protein S2 (RPS2) axis

    DOI:10.1080/21655979.2022.2042999

    影响因子 :4.9

    引用产品: 人脐静脉内皮细胞 ,  SH-SY5Y [SHSY-5Y] 细胞 ,  SK-N-SH 细胞 ,  SK-N-AS 细胞 ,  SK-N-BE (2) 细胞

  • CDC27-ODC1 Axis Promotes Metastasis, Accelerates Ferroptosis and Predicts Poor Prognosis in Neuroblastoma (2002-02-20)

    作者:Lin Qiu:1.Department of Hematology/Oncology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. ; Rui Zhou:1.Department of General Surgery, The Third Affiliated Hospital of Southern Medical University, Southern Medical University, Guangzhou, China. ; 2.Department of Hepatobiliary Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. ; Ziyan Luo:1.Department of Hematology/Oncology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. ; Jiangxue Wu:1.State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China. ; Hua Jiang:1.Department of Hematology/Oncology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. ;

    期刊:CDC27-ODC1 Axis Promotes Metastasis, Accelerates Ferroptosis and Predicts Poor Prognosis in Neuroblastoma

    DOI:10.3389/fonc.2022.774458

    影响因子 :4.7

    引用产品: SK-N-SH 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞

  • Energy metabolism disorders and oxidative stress in the SH-SY5Y cells following PM2.5 air pollution exposure (2022-08-23)

    作者:Zhaofei Li:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; Fengjie Tian:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; Hongfang Ban:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; Shuangshuang Xia:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; Lixia Cheng:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; Xueke Ren:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China. ; Yi Lyu:1.Department of Health Toxicology, School of Public Health in Shanxi Medical University, Taiyuan 030001, China; Department of Biochemistry and Molecular Biology, School of Preclinical Medicine in Shanxi Medical University, Taiy

    期刊:Energy metabolism disorders and oxidative stress in the SH-SY5Y cells following PM2.5 air pollution exposure

    DOI:10.1016/j.toxlet.2022.08.008

    影响因子 :4.3

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基 ,  特级胎牛血清

  • Midazolam alleviates cellular senescence in SH-SY5Y neuronal cells in Alzheimer's disease (2022-11-28)

    作者:Ping Wang:1.Department of Anesthesiology, The First People's Hospital of Lianyungang, Xuzhou Medical University Affiliated Hospital of Lianyungang, Lianyungang, Jiangsu, China. ; Peipei Wang:1.Department of Anesthesiology, The First People's Hospital of Lianyungang, Xuzhou Medical University Affiliated Hospital of Lianyungang, Lianyungang, Jiangsu, China. ; Hengfei Luan:1.Department of Anesthesiology, The First People's Hospital of Lianyungang, Xuzhou Medical University Affiliated Hospital of Lianyungang, Lianyungang, Jiangsu, China. ; Yong Wu:1.Department of Anesthesiology, The First People's Hospital of Lianyungang, Xuzhou Medical University Affiliated Hospital of Lianyungang, Lianyungang, Jiangsu, China. ; Ying Chen:1.Department of Anesthesiology, The First People's Hospital of Lianyungang, Xuzhou Medical University Affiliated Hospital of Lianyungang, Lianyungang, Jiangsu, China. ;

    期刊:Midazolam alleviates cellular senescence in SH-SY5Y neuronal cells in Alzheimer's disease

    DOI:10.1002/brb3.2822

    影响因子 :3.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Itaconate Attenuates Neuroinflammation and Exerts Dopamine Neuroprotection in Parkinson’s Disease through Inhibiting NLRP3 Inflammasome (2022-09-16)

    作者:Guoqing Sun:1.Department of Anesthesiology, Shandong Provincial Hospital, Shandong University, Jinan 250021, China. ; Rui Zhang:1.Department of Neurosurgery, Shandong Provincial Hospital, Shandong University, Jinan 250021, China. ; Chengxiao Liu:1.Department of Anesthesiology, Shandong Provincial Hospital, Shandong University, Jinan 250021, China. ; Wenjun Meng:1.Department of Anesthesiology, Shandong Provincial Hospital, Shandong University, Jinan 250021, China. ; Qi Pang:1.Department of Neurosurgery, Shandong Provincial Hospital, Shandong University, Jinan 250021, China. ;

    期刊:Itaconate Attenuates Neuroinflammation and Exerts Dopamine Neuroprotection in Parkinson’s Disease through Inhibiting NLRP3 Inflammasome

    DOI:10.3390/brainsci12091255

    影响因子 :3.3

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance (2022-12-01)

    作者:Yi Lyu:1.Department of Health Toxicology, School of Public Health, Shanxi Medical University, China. ; 2.Department of Biochemistry and Molecular Biology, School of Preclinical Medicine, Shanxi Medical University, China. ; Xue-Ke Ren:1.Department of Health Toxicology, School of Public Health, Shanxi Medical University, China. ; Can-Can Guo:1.Department of Health Toxicology, School of Public Health, Shanxi Medical University, China. ; Zhao-Fei Li:1.Department of Health Toxicology, School of Public Health, Shanxi Medical University, China. ; Jin-Ping Zheng:1.Department of Health Toxicology, School of Public Health, Shanxi Medical University, China. ; 2.Collaborative Innovation Center for Aging Mechanism Research and Transformation, Center for Healthy Aging, Changzhi Medical College, China. ;

    期刊:Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance

    DOI:10.2131/jts.47.519

    影响因子 :1.8

    引用产品: MEM/F12 培养基 ,  特级胎牛血清 ,  SH-SY5Y [SHSY-5Y] 细胞

  • Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimers disease by enhancing autophagy (2001-01-20)

    作者:Meng-Lu Chen:1.Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. ; 2.Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. ; Chun-Gu Hong:1.Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. ; 2.Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong 518035, China. ; Tao Yue:1.Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. ; 2.Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. ; Hong-Ming Li:1.Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. ; 2.Movement System Injury and Repair Research Center, Xiangya Hospital, Central South University, Changsha, Hunan 4

    期刊:Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimers disease by enhancing autophagy

    DOI:10.7150/thno.47408

    影响因子 :12.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • HMGB3 is Associated With an Unfavorable Prognosis of Neuroblastoma and Promotes Tumor Progression by Mediating TPX2 (2012-01-20)

    作者:Xiaodan Zhong:1.Department of Pediatric Oncology, The First Hospital of Jilin University, Changchun, China. ; Songling Zhang:1.Department of Obstetrics and Gynecology, The First Hospital of Jilin University, Changchun, China. ; Yutong Zhang:1.Department of Pediatric Oncology, The First Hospital of Jilin University, Changchun, China. ; Zongmiao Jiang:1.Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, China. ; Yanan Li:1.Department of Pediatrics, The First Hospital of Jilin University, Changchun, China. ; Jian Chang:1.Department of Pediatric Oncology, The First Hospital of Jilin University, Changchun, China. ; Junqi Niu:1.Department of Hepatology, The First Hospital of Jilin University, Changchun, China. ; Ying Shi:1.Department of Hepatology, The First Hospital of Jilin University, Changchun, China. ;

    期刊:HMGB3 is Associated With an Unfavorable Prognosis of Neuroblastoma and Promotes Tumor Progression by Mediating TPX2

    DOI:10.3389/fcell.2021.769547

    影响因子 :5.5

    引用产品: SK-N-SH 细胞 ,  SH-SY5Y [SHSY-5Y] 细胞 ,  SK-N-BE (2) 细胞

  • Effects of miRNAs in exosomes derived from α-synuclein overexpressing SH-SY5Y cells on autophagy and inflammation of microglia (2010-01-20)

    作者:Tianen Zhou:1.Department of Emergency, The First People's Hospital of Foshan, Foshan 528000, China. ; Meng Zhang:1.Department of General Practice, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China. ; Yingyu Xie:1.Department of Neurology, Shantou Central Hospital, Shantou 515000, China. ; Ying Chen:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China. ; Sudan Peng:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China. ; Xiuna Jing:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China. ; Ming Lei:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China. ; Enxiang Tao:1.Department of Neurology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen 518033, China. Electronic address: taoex@mail.sysu.edu.cn. ; Yanran Liang:1.Department of Neu

    期刊:Effects of miRNAs in exosomes derived from α-synuclein overexpressing SH-SY5Y cells on autophagy and inflammation of microglia

    DOI:10.1016/j.cellsig.2021.110179

    影响因子 :4.8

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • The protective effects of Agomelatine against Aβ1-42 oligomers-induced cellular senescence mediated by SIRT6 and Agomelatine’s potential in AD treatment (2009-01-20)

    作者:Jian Wang:1.Department of Neurology, Ya'an Peoples Hospital, Ya'an, 625000, Sichuan, China. ; Bo Zheng:1.Department of Neurology, Ya'an Peoples Hospital, Ya'an, 625000, Sichuan, China. ; Shu Yang:1.Department of Neurology, The Affiliated Hospital of University of Electronic Science and Technology, Sichuan Provincial People's Hospital, No. 32, West Second Section, First Ring Road, Qingyang District, Chengdu, 610000, Sichuan, China. ; Fang Wang:1.West China Hospital, Innovation Center of Nursing Research, Sichuan University, Chengdu, 610041, China. ; 2.Nursing Key Laboratory of Sichuan Province, Sichuan University, Chengdu, 610041, China. ; Zhonglin Wang:1.Department of Neurology, The Fifth Hospital of Deyang, 531 Huashan North Road, Jingyang District, Deyang City, 610000, Sichuan, China. zhaoxiaqinz6h@163.com. ; Jianhong Wang:1.Department of Neurology, The Affiliated Hospital of University of Electronic Science and Technology, Sichuan Provincial People's Hospital, No. 32, West Seco

    期刊:The protective effects of Agomelatine against Aβ1-42 oligomers-induced cellular senescence mediated by SIRT6 and Agomelatine’s potential in AD treatment

    DOI:10.1007/s13577-021-00611-2

    影响因子 :4.4

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • miR-146a aggravates cognitive impairment and Alzheimer disease-like pathology by triggering oxidative stress through MAPK signaling (2003-01-20)

    作者:H Zhan-Qiang:1.Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China. ; Q Hai-Hua:1.Department of Dermatology, Affiliated Hospital of Chengde Medical College, Chengde 067000, China. ; Z Chi:1.Department of Neurology, Affilicated Hospital of Chengde Medical College, Chengde 067000, China. ; W Miao:1.Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China. ; Z Cui:1.Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China. ; L Zi-Yin:1.Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China. ; H Jing:1.Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China. ; W Yi-Wei:1.Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China. Electronic address: wangyiwei9511_cmc@163.com. ;

    期刊:miR-146a aggravates cognitive impairment and Alzheimer disease-like pathology by triggering oxidative stress through MAPK signaling

    DOI:10.1016/j.nrl.2020.12.006

    影响因子 :3.9

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  DMEM/F12 (含HEPES) 培养基

  • The neuroprotective effects of Insulin-Like Growth Factor 1 via the Hippo/YAP signaling pathway are mediated by the PI3K/AKT cascade following cerebral ischemia/reperfusion injury (2010-01-20)

    作者:Pian Gong:1.Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, PR China. ; Yichun Zou:1.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, PR China. ; Wei Zhang:1.Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, PR China. ; Qi Tian:1.Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, PR China. ; Shoumeng Han:1.Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, PR China. ; Zhou Xu:1.Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, PR China. ; Qianxue Chen:1.Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, PR China. ; Xin Wang:1.Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ; Mingchang Li:1.Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 4300

    期刊:The neuroprotective effects of Insulin-Like Growth Factor 1 via the Hippo/YAP signaling pathway are mediated by the PI3K/AKT cascade following cerebral ischemia/reperfusion injury

    DOI:10.1016/j.brainresbull.2021.10.017

    影响因子 :3.7

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment (2012-01-20)

    作者:Changhong Tan:1.Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, 74 Linjiang Road, Yuzhong District, Chongqing, 400010, China. ; Xi Liu:1.Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, 74 Linjiang Road, Yuzhong District, Chongqing, 400010, China. ; Xiaoshuai Zhang:1.Chongqing Medical University, Chongqing, 400010, China. ; Wuxue Peng:1.Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, 74 Linjiang Road, Yuzhong District, Chongqing, 400010, China. ; Hui Wang:1.Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, 74 Linjiang Road, Yuzhong District, Chongqing, 400010, China. ; Wen Zhou:1.Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, 74 Linjiang Road, Yuzhong District, Chongqing, 400010, China. ; Jin Jiang:1.Department of Neurology, The Second Affiliated Hospital of Chongqing Medical Univ

    期刊:Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment

    DOI:10.1186/s12860-021-00398-y

    影响因子 :2.8

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • MiR‐370 accelerated cerebral ischemia reperfusion injury via targeting SIRT6 and regulating Nrf2/ARE signal pathway (2004-00-20)

    作者:Zhong-Fan Ruan:1.Department of Neurology, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China. ; Ming Xie:1.Department of Neurology, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China. ; Shu-Jia Gui:1.Department of Neurology, Affiliated Nanhua Hospital, University of South China, Hengyang City, Hunan Province, China. ; Fang Lan:1.Department of Neurology, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China. ; Juan Wan:1.Department of Neurology, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China. ; Yan Li:1.Department of Anesthesiology, Affiliated Nanhua Hospital, University of South China, Hengyang City, Hunan Province, China. ;

    期刊:MiR‐370 accelerated cerebral ischemia reperfusion injury via targeting SIRT6 and regulating Nrf2/ARE signal pathway

    DOI:10.1002/kjm2.12219

    影响因子 :3.3

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • Novel Deoxyvasicinone–Donepezil Hybrids as Potential Multitarget Drug Candidates for Alzheimer’s Disease (2002-09-20)

    作者:Hongtao Du:1.College of Life Science , Xinyang Normal University , Xinyang 464000 , China. ; 2.College of Plant Protection , Northwest A&F University , Yangling 712100 , Shaanxi Province , China. ; Xinlian Liu:1.College of Life Science , Xinyang Normal University , Xinyang 464000 , China. ; 2.Tea Plant Biology Key Laboratory of Henan Province , Xinyang 464000 , China. ; Jusen Xie:1.College of Life Science , Xinyang Normal University , Xinyang 464000 , China. ; 2.Tea Plant Biology Key Laboratory of Henan Province , Xinyang 464000 , China. ; Fang Ma:1.School of Geographic Sciences , Xinyang Normal University , Xinyang 464000 , China. ;

    期刊:Novel Deoxyvasicinone–Donepezil Hybrids as Potential Multitarget Drug Candidates for Alzheimer’s Disease

    DOI:10.1021/acschemneuro.8b00699

    影响因子 :5.0

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  Hep G2 细胞

  • α-synuclein accumulation in SH-SY5Y cell impairs autophagy in microglia by exosomes overloading miR-19a-3p (2001-09-20)

    作者:Tianen Zhou:1.Department of Emergency, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, PR China. ; Danyu Lin:1.Department of Neurology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong 518033, PR China. ; Ying Chen:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, PR China. ; Sudan Peng:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, PR China. ; Xiuna Jing:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, PR China. ; Ming Lei:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, PR China. ; Enxiang Tao:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, PR China. ; Yanran Liang:1.Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, PR China.

    期刊:α-synuclein accumulation in SH-SY5Y cell impairs autophagy in microglia by exosomes overloading miR-19a-3p

    DOI:10.2217/epi-2019-0222

    影响因子 :3.8

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • MiR‐29c protects against inflammation and apoptosis in Parkinsons disease model in vivo and in vitro by targeting SP1 (2012-09-20)

    作者:Ruili Wang:1.Department of Geriatric Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. ; Ying Yang:1.Department of Geriatric Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. ; Hui Wang:1.Department of Geriatric Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. ; Ya He:1.Department of Geriatric Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. ; Chen Li:1.Department of Geriatric Neurology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. ;

    期刊:MiR‐29c protects against inflammation and apoptosis in Parkinsons disease model in vivo and in vitro by targeting SP1

    DOI:10.1111/1440-1681.13212

    影响因子 :2.9

    引用产品: SH-SY5Y [SHSY-5Y] 细胞

  • miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress (2009-09-20)

    作者:Lumei Chi:1.Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, 130033, People's Republic of China. ; Dan Jiao:1.Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, 130033, People's Republic of China. ; Guangxian Nan:1.Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, 130033, People's Republic of China. ; Honghua Yuan:1.Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, 130033, People's Republic of China. ; Jing Shen:1.Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, 130033, People's Republic of China. ; Yu Gao:1.Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, 130033, People's Republic of China. Electronic address: yugaosmile@163.com. ;

    期刊:miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress

    DOI:10.1016/j.acthis.2019.08.005

    影响因子 :2.5

    引用产品: SH-SY5Y [SHSY-5Y] 细胞 ,  MEM/F12 培养基

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