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| 名称 | 22RV1 (人前列腺癌细胞) (STR鉴定正确) |
| 别称 | 22RV1; 22Rv-1; 22rV1; CWR22-Rv1; CWR22R-V1; CWR22-R1; CWR22Rv1; CWR22R |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：90%FBS+10%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 22RV1细胞复苏时需要离心去除DMSO。冻存细胞复苏最初阶段，贴壁量少，成簇松散贴壁，但是最终细胞会变平并且扩散成很好的单层，这个过程需要4-5天时间。细胞生长缓慢，细胞只能生长到90%的汇合度。细胞冻存后复苏成活率不高，推荐冻存液配比为90%FBS+10% DMSO，使用优质血清。 |
| 背景描述 | 22RV1是来自异种移植(在阉割引起前列腺癌衰退又在其父亲的雄性激素信赖型CWR22嫁接后复发的小鼠中连续传代)的人前列腺癌上皮细胞系；22RV1细胞系表达前列腺特异抗原。二羟基睾丸脂酮轻微刺激22RV1细胞生长，经Western Blot检测溶解产物与抗雄性激素受体抗体起免疫反应；EGF刺激22RV1细胞生长，但TGFβ-1不能抑制细胞生长；22RV1可在裸鼠中成瘤。 |
| 年龄（性别） | 男性 |
| 组织来源 | 前列腺 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 前列腺癌细胞 |
| 生物安全等级 | BSL-2 |
| 倍增时间 | ~40 hours |
| 致瘤性 | Yes, forms tumors in nude mice. |
| 受体表达情况 | androgen receptor |
| 保藏机构 | ATCC; CRL-2505 BCRC; 60545 DSMZ; ACC-438 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,11 D2S1338 17,18 D3S1358 15 D5S818 11,13 D7S820 9,10,11 D8S1179 13,14 D13S317 9,12 D16S539 12 D18S51 13,14 D19S433 13,14 D21S11 30 FGA 19,23 PentaD 9,12 PentaE 5,13 TH01 6,9.3 TPOX 8 vWA 15,21 D6S1043 16 D12S391 18,25 D2S441 11,12 -
STR鉴定图
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参考文献
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Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer (2024-03-21)
作者：Da Ren:1.Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. ; 2.Uro-Oncology Institute of Central South University, Changsha, Hunan, 410011, China. ; Wei Li:1.Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. ; 2.Uro-Oncology Institute of Central South University, Changsha, Hunan, 410011, China. ; Ruijiang Zeng:1.Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. ; 2.Uro-Oncology Institute of Central South University, Changsha, Hunan, 410011, China. ; Xinlin Liu:1.Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. ; 2.Uro-Oncology Institute of Central South University, Changsha, Hunan, 410011, China. ; Huaiyuan Liang:1.Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. ; 2.Uro-Oncology Insti
期刊：Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer
DOI：10.1038/s41418-024-01282-w
影响因子 ：12.4
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YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation (2024-03-09)
作者：Xuefeng Zhao:1.Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Suli Lv:1.Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Neng Li:1.Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Qingli Zou:1.Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ; Lidong Sun:1.Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Cell Architecture Research Institute, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic addre
期刊：YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation
影响因子 ：4.8
引用产品： PC-3 细胞 , DU 145 细胞 , 22RV1 细胞 , Ham's F-12K 培养基 , MEM (含NEAA) 培养基 , RPMI-1640 培养基
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Epigenetic activation of METTL14 promotes docetaxel resistance in prostate cancer by promoting pri-microRNA-129 maturation (2024-03-28)
作者：Cheng Wu:1.Department of Urology, Dongtai City People's Hospital, Dongtai, Jiangsu, China. ; 2.Department of Urology, Dongtai Hospital, the Affiliated Hospital of Jiangsu Vocational College of Medicine, Dongtai, Jiangsu, China. ; Chunqing Miao:1.Public Health Section, Dongtai City People's Hospital, Dongtai, Jiangsu, China. ; Songlin Zhou:1.Department of Urology, Dongtai City People's Hospital, Dongtai, Jiangsu, China. ; Ping-An Chang:1.Department of Urology, Dongtai City People's Hospital, Dongtai, Jiangsu, China. ; Bin He:1.Department of Urology, Dongtai City People's Hospital, Dongtai, Jiangsu, China. ; Xunrong Zhou:1.Department of Urology, Dongtai City People's Hospital, Dongtai, Jiangsu, China. ; Qingsheng Tang:1.Department of Urology, Dongtai City People's Hospital, Dongtai, Jiangsu, China. ;
期刊：Epigenetic activation of METTL14 promotes docetaxel resistance in prostate cancer by promoting pri-microRNA-129 maturation
影响因子 ：4.5
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A morpholine derivative N-(4-morpholinomethylene)ethanesulfonamide induces ferroptosis in tumor cells by targeting NRF2 (2024-01-30)
作者：Bingchun Sun:1.First Affiliated Hospital of Jinan University. ; Ligang Zhang:1.School of Medicine, Foshan University. ; Binhua Wu:1.Department of Obstetrics and Gynecology of Affiliated Hospital, the Marine Biomedical Research Institute, Guangdong Medical University. ; Xiping Luo:1.First Affiliated Hospital of Jinan University. ; 2.Department of Gynecology, Guangdong Women and Children Hospital. ;
期刊：A morpholine derivative N-(4-morpholinomethylene)ethanesulfonamide induces ferroptosis in tumor cells by targeting NRF2
影响因子 ：2.0
引用产品： 22RV1 细胞 , LNCaP clone FGC 细胞 , C4-2 细胞 , SK-OV-3 细胞
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Synthesis of curcumin derivatives for suppression of castration-resistant prostate cancer (2024-02-06)
作者：Taizhou Vocational and Technical College, Taizhou, P. R. China. School of Pharmacy, Changzhou University, Changzhou, P. R. China Jiangsu Hope-Pharm Co., Ltd, Changzhou, P. R. China
期刊：Synthesis of curcumin derivatives for suppression of castration-resistant prostate cancer
影响因子 ：1.4
引用产品： 22RV1 细胞
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A Liquid–Liquid Phase Separation-Related Index Associate with Biochemical Recurrence and Tumor Immune Environment of Prostate Cancer Patients (2023-03-14)
作者：Qi You:1.Department of Urology, Urology Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China. ; 2.Department of Urology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China. ; Jia-Yin Chen:1.Department of Urology, Urology Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China. ; 2.Department of Urology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China. ; Xiao-Hui Wu:1.Department of Urology, Urology Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China. ; 2.Department of Urology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China. ; Yu-Ting Xue:1.Department of Urology, Urology Research Institute, The First Affiliated
期刊：A Liquid–Liquid Phase Separation-Related Index Associate with Biochemical Recurrence and Tumor Immune Environment of Prostate Cancer Patients
影响因子 ：5.6
引用产品： RWPE-1 细胞 , 22RV1 细胞 , PC-3 细胞 , DU 145 细胞 , DU 145细胞专用培养基 , PC-3细胞专用培养基
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Identification and validation of a novel overall survival prediction model for immune-related genes in bone metastases of prostate cancer (2023-07-25)
作者：Wen Bi:1.Department of Sports Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China. ; Weiming Guo:1.Department of Sports Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China. ; Gang Fan:1.Department of Urology, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China. ; Lei Xie:1.Department of Urology, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China. ; Changqing Jiang:1.Department of Sports Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Ce
期刊：Identification and validation of a novel overall survival prediction model for immune-related genes in bone metastases of prostate cancer
影响因子 ：5.2
引用产品： PC-3 细胞 , DU 145 细胞 , LNCaP clone FGC 细胞 , 22RV1 细胞 , RPMI-1640 培养基
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177Lu-Labeled Bivalent Ligands of Prostate-Specific Membrane Antigen for Endoradiotherapy of Prostate Cancer (2023-12-28)
作者：Ruoxue Dai:1.GDMPA Key Laboratory for Quality Control and Evaluation of Radiopharmaceuticals, Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, P. R. China. ; Zhikai Cai:1.GDMPA Key Laboratory for Quality Control and Evaluation of Radiopharmaceuticals, Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, P. R. China. ; Rui Hu:1.GDMPA Key Laboratory for Quality Control and Evaluation of Radiopharmaceuticals, Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, P. R. China. ; Yueqi Huang:1.GDMPA Key Laboratory for Quality Control and Evaluation of Radiopharmaceuticals, Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, P. R. China. ; Lilan Fu:1.GDMPA Key Laboratory for Quality Control and Evaluation of Radiopharmaceuticals, Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guan
期刊：177Lu-Labeled Bivalent Ligands of Prostate-Specific Membrane Antigen for Endoradiotherapy of Prostate Cancer
DOI：10.1021/acs.molpharmaceut.3c00987
影响因子 ：4.9
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Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer (2023-08-16)
作者：Hongzhuang Wen:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Changbao Qu:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Zhu Wang:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Haitao Gao:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Wuyao Liu:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Hu Wang:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Hao Sun:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Junfei Gu:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Zhan Yang:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; 2.Molecular Biology Labora
期刊：Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer
影响因子 ：4.8
引用产品： LNCaP clone FGC 细胞 , PC-3 细胞 , 22RV1 细胞
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USF1-mediated ALKBH5 stabilizes FLII mRNA in an m6A-YTHDF2-dependent manner to repress glycolytic activity in prostate adenocarcinoma (2023-07-26)
作者：Dewang Fu:1.Department of Urology Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China. ; Qingyue Si:1.Department of Urology Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China. ; Chenxi Yu:1.Department of Urology Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China. ; Zhifu Han:1.Department of Urology Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China. ; Li'e Zang:1.Department of Neurology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, P.R. China. ;
期刊：USF1-mediated ALKBH5 stabilizes FLII mRNA in an m6A-YTHDF2-dependent manner to repress glycolytic activity in prostate adenocarcinoma
DOI：10.1002/mc.23609
影响因子 ：4.6
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Crafting a Personalized Prognostic Model for Malignant Prostate Cancer Patients Using Risk Gene Signatures Discovered through TCGA-PRAD Mining, Machine Learning, and Single-Cell RNA-Sequencing (2023-06-07)
作者：Feng Lyu:1.Department of Radiation Oncology, Peking University First Hospital, Beijing 100034, China. ; Xianshu Gao:1.Department of Radiation Oncology, Peking University First Hospital, Beijing 100034, China. ; Mingwei Ma:1.Department of Radiation Oncology, Peking University First Hospital, Beijing 100034, China. ; Mu Xie:1.Department of Radiation Oncology, Peking University First Hospital, Beijing 100034, China. ; Shiyu Shang:1.Department of Radiation Oncology, Peking University First Hospital, Beijing 100034, China. ; 2.First Clinical Medical School, Hebei North University, Zhangjiakou 075000, China. ; Xueying Ren:1.Department of Radiation Oncology, Peking University First Hospital, Beijing 100034, China. ; Mingzhu Liu:1.Department of Radiation Oncology, Peking University First Hospital, Beijing 100034, China. ; Jiayan Chen:1.Department of Radiation Oncology, Peking University First Hospital, Beijing 100034, China. ;
期刊：Crafting a Personalized Prognostic Model for Malignant Prostate Cancer Patients Using Risk Gene Signatures Discovered through TCGA-PRAD Mining, Machine Learning, and Single-Cell RNA-Sequencing
DOI：10.3390/diagnostics13121997
影响因子 ：3.6
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IU1 and enzalutamide combination yields synergistic effects on castration-resistant prostate cancer (2023-08-07)
作者：Yifan Zhang:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangdong, Guangzhou, China. ; Yuanpeng Liao:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangdong, Guangzhou, China. ; Mayao Luo:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangdong, Guangzhou, China. ; Yuedian Ye:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangdong, Guangzhou, China. ; Zhuofan Xu:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangdong, Guangzhou, China. ; Wenli Hou:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangdong, Guangzhou, China. ; Ruiyu Liu:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangdong, Guangzhou, China. ; Qiliang Zhai:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangdong, Guangzhou, China. ; Shidong Lv:1.Department of Urology, Nanfang Hospital, Southern Medical Univer
期刊：IU1 and enzalutamide combination yields synergistic effects on castration-resistant prostate cancer
影响因子 ：2.8
引用产品： LNCaP clone FGC 细胞 , C4-2 细胞 , 22RV1 细胞 , PC-3 细胞
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Exploring the role of differentially expressed metabolic genes and their mechanisms in bone metastatic prostate cancer (2023-04-12)
作者：Qingfu Zhang:1.Department of Urology, Tai 'an Central Hospital, Tai 'an, Shandong, China. ; Peng Zhang:1.Department of Spine Surgery, Tai 'an Central Hospital, Tai 'an, Shandong, China. ; Zhongting Zhao:1.Department of Spinal Surgery, The Third People's Hospital of Jinan, Jinan, Shandong, China. ; Jun Wang:1.Department of Emergency, Qingdao Eighth People's Hospital, Qingdao, China. ; Hepeng Zhang:1.Department of Urology, Tai 'an Central Hospital, Tai 'an, Shandong, China. ;
期刊：Exploring the role of differentially expressed metabolic genes and their mechanisms in bone metastatic prostate cancer
影响因子 ：2.7
引用产品： PC-3 细胞 , DU 145 细胞 , LNCaP clone FGC 细胞 , 22RV1 细胞
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Circular RNA Dipeptidyl Peptidase 4 (circDPP4) Stimulates the Expression of Glutamate Dehydrogenase 1 to Contribute to the Malignant Phenotypes of Prostate Cancer by Sponging miR-497-5p (2023-04-20)
作者：Long Pei:1.Department of Urology, The Fourth Hospital of Hebei Medical University, No. 12, Jiankang Road, Chang'an District, Shijiazhuang, 050000, China. ; Xiaosen Song:1.Department of Urology, The Fourth Hospital of Hebei Medical University, No. 12, Jiankang Road, Chang'an District, Shijiazhuang, 050000, China. ; Xiangdong Liang:1.Department of Urology, The Fourth Hospital of Hebei Medical University, No. 12, Jiankang Road, Chang'an District, Shijiazhuang, 050000, China. ; Ming Li:1.Department of Urology, The Fourth Hospital of Hebei Medical University, No. 12, Jiankang Road, Chang'an District, Shijiazhuang, 050000, China. ; Aili Zhang:1.Department of Urology, The Fourth Hospital of Hebei Medical University, No. 12, Jiankang Road, Chang'an District, Shijiazhuang, 050000, China. ; Xiaoliang Tan:1.Department of Urology, The Fourth Hospital of Hebei Medical University, No. 12, Jiankang Road, Chang'an District, Shijiazhuang, 050000, China. sephbqp@163.com. ;
期刊：Circular RNA Dipeptidyl Peptidase 4 (circDPP4) Stimulates the Expression of Glutamate Dehydrogenase 1 to Contribute to the Malignant Phenotypes of Prostate Cancer by Sponging miR-497-5p
DOI：10.1007/s12033-023-00750-x
影响因子 ：2.6
引用产品： 22RV1 细胞 , RWPE-1 细胞 , RPMI-1640 培养基
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Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer (2022-09-01)
作者：Shidong Lv:1.Department of Urology, Nanfang Hospital, Southern Medical University-Guangzhou, Guangzhou, China. ; 2.Department of Urology, University of Pittsburgh School of Medicine-Pittsburgh, Pittsburgh, PA, USA. ; Zeyu Wu:1.Department of Urology, University of Pittsburgh School of Medicine-Pittsburgh, Pittsburgh, PA, USA. ; 2.Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University-Changsha, Changsha, China. ; Mayao Luo:1.Department of Urology, Nanfang Hospital, Southern Medical University-Guangzhou, Guangzhou, China. ; Yifan Zhang:1.Department of Urology, Nanfang Hospital, Southern Medical University-Guangzhou, Guangzhou, China. ; Jianqiang Zhang:1.Department of Urology, Nanfang Hospital, Southern Medical University-Guangzhou, Guangzhou, China. ; 2.Department of urology surgery department ward III, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine-Nanning, Guangxi, China. ; Laura E Pascal:1.Department of Urology, University of
期刊：Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer
DOI：10.1038/s41419-022-05182-0
影响因子 ：9.7
引用产品： LNCaP clone FGC 细胞 , VCaP 细胞 , 22RV1 细胞
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Tautomycin and enzalutamide combination yields synergistic effects on castration-resistant prostate cancer (2022-11-29)
作者：Mayao Luo:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China. ; Yifan Zhang:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China. ; Zhuofan Xu:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China. ; Chenwei Wu:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China. ; Yuedian Ye:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China. ; Rui Liu:1.School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, China. liurui2011hgd@163.com. ; Shidong Lv:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China. lsd990@163.com. ; Qiang Wei:1.Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515
期刊：Tautomycin and enzalutamide combination yields synergistic effects on castration-resistant prostate cancer
DOI：10.1038/s41420-022-01257-1
影响因子 ：7.1
引用产品： LNCaP clone FGC 细胞 , C4-2 细胞 , 22RV1 细胞
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Synthesis and bioactivity evaluation of ferrocene-based hydroxamic acids as selective histone deacetylase 6 inhibitors (2022-12-07)
作者：Jiangkun Yan:1.Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 26003, Shandong, PR China; Laboratory for Marine Drugs and Bioproducts, Center for Innovation Marine Drug Screening & Evaluation, Pilot National Laboratory for Marine Science and Technology, Qingdao, 266200, PR China. ; Kairui Yue:1.Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 26003, Shandong, PR China; Laboratory for Marine Drugs and Bioproducts, Center for Innovation Marine Drug Screening & Evaluation, Pilot National Laboratory for Marine Science and Technology, Qingdao, 266200, PR China. ; Xuejing Fan:1.Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 26003, Shandong, PR China; Laboratory for Marine Drugs and Bioproducts, Center for Innovation Marine Drug Screening & Ev
期刊：Synthesis and bioactivity evaluation of ferrocene-based hydroxamic acids as selective histone deacetylase 6 inhibitors
DOI：10.1016/j.ejmech.2022.115004
影响因子 ：7.1
引用产品： 22RV1 细胞 , MM.1S 细胞 , MV-4-11 细胞 , JeKo-1 细胞 , 4T1 细胞 , DMEM高糖 培养基
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Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression (2022-10-17)
作者：An-Ning Zhao:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Zhan Yang:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; 2.Molecular Biology Laboratory, Talent and Academic Exchange Center, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Dan-Dan Wang:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Bei Shi:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Hong Zhang:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Yang Bai:1.Department of Biochemistry and Molecular Biology, Ministry of Education of China, Hebei Medical University, Shijiazhuang, China. ; Bo-Wen Yan:1.Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China. ; Yong Zhang:1.Department of Urology, Cancer Hospital, Chinese A
期刊：Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor-promoted inflammatory responses and prostate cancer progression
影响因子 ：5.8
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HMGB1 promotes the development of castration‑resistant prostate cancer by regulating androgen receptor activation (2022-09-19)
作者：Junyu Chen:1.Department of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China. ; Duo Xu:1.Department of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China. ; Taiwei Wang:1.Department of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China. ; Zhaoyun Yang:1.Department of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China. ; Yanrong Yang:1.School of Medicine, Tongji University, Shanghai 200092, P.R. China. ; Kang He:1.Department of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China. ; Lijing Zhao:1.Department of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China. ;
期刊：HMGB1 promotes the development of castration‑resistant prostate cancer by regulating androgen receptor activation
影响因子 ：4.1
引用产品： LNCaP clone FGC 细胞 , 22RV1 细胞
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GPX2 predicts recurrence-free survival and triggers the Wnt/β-catenin/EMT pathway in prostate cancer (2022-10-25)
作者：Ming Yang:1.The Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ; Xudong Zhu:1.The Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ; Yang Shen:1.The Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ; Qi He:1.The Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ; Yuan Qin:1.The Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ; Yiqun Shao:1.Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China. ; Lin Yuan:1.Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ; Hesong Ye:1.The Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ;
期刊：GPX2 predicts recurrence-free survival and triggers the Wnt/β-catenin/EMT pathway in prostate cancer
影响因子 ：3.1
引用产品： PC-3 细胞 , DU 145 细胞 , LNCaP clone FGC 细胞 , 22RV1 细胞
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LOC100996425 acts as a promoter in prostate cancer by mediating hepatocyte nuclear factor 4A and the AMPK/mTOR pathway (2008-01-20)
作者：Xiuyan Wang:1.Department of Urology, The Second Hospital of Jilin University, Changchun, China. ; Bin Song:1.Department of Neurosurgery, The Second Hospital of Jilin University, Changchun, China. ; Mingcui Zang:1.Department of Hepatobiliary and Pancreatic Surgery I, The First Hospital of Jilin University, Changchun, China. ; He Ji:1.Department of Gynaecology, The Second Hospital of Jilin University, Changchun, China. ; He Yang:1.Department of Urology, The Second Hospital of Jilin University, Changchun, China. ; Shuang Jiang:1.Department of Urology, The Second Hospital of Jilin University, Changchun, China. ; Xiao Yang:1.Department of Urology, The Second Hospital of Jilin University, Changchun, China. ;
期刊：LOC100996425 acts as a promoter in prostate cancer by mediating hepatocyte nuclear factor 4A and the AMPK/mTOR pathway
影响因子 ：5.3
引用产品： C4-2 细胞 , PC-3 细胞 , 22RV1 细胞 , LNCaP clone FGC 细胞 , DU 145 细胞
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MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways (2011-01-20)
作者：Sihai Zhou:1.Department of Urology, The Second Affiliated Hospital of Dalian Medical University, DaLian, China. ; Zhihong Dai:1.Department of Urology, The Second Affiliated Hospital of Dalian Medical University, DaLian, China. ; Liang Wang:1.Department of Urology, The Second Affiliated Hospital of Dalian Medical University, DaLian, China. ; Xiang Gao:1.Department of Urology, The Second Affiliated Hospital of Dalian Medical University, DaLian, China. ; Liqin Yang:1.Department of Urology, The Second Affiliated Hospital of Dalian Medical University, DaLian, China. ; Zhenwei Wang:1.Department of Urology, Guangdong Second Provincial General Hospital, Guangzhou, China. ; Qi Wang:1.Department of Respiratory Medicine, The Second Affiliated Hospital of Dalian Medical University, DaLian, China. ; Zhiyu Liu:1.Department of Urology, The Second Affiliated Hospital of Dalian Medical University, DaLian, China. ;
期刊：MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways
影响因子 ：5.3
引用产品： DU 145 细胞 , PC-3 细胞 , LNCaP clone FGC 细胞 , 22RV1 细胞
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