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产品概述
名称 | HEC-1-B (人子宫内膜腺癌细胞) (STR鉴定正确) |
别称 | Hec-1-B; HEC-1B; HEC1-B; HEC1B; Hec1B |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养方案A(默认) |
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
|
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2-3次/周 |
背景描述 | HEC-1-B细胞是由H·Kuramoto于1968年分离的HEC-1-A细胞亚株。不同于HEC-A-1的是:HEC-1-B细胞在培养第135天到190天之间表现出稳定的生长周期,且重现扁平,与亲本细胞系相比更具铺路石样。此外,HEC-1-B细胞的主要染色体组是亲本细胞的两倍。 |
年龄(性别) | 女性;71岁 |
组织来源 | 子宫内膜腺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 子宫内膜腺癌 |
生物安全等级 | BSL-1 |
致瘤性 | Yes, in nude mice (The cells form moderately well differentiated adenocarcinomas consistent with endometrial carcinoma (grade II)).Yes, in the cheek pouch of cortisone treated hamsters (The cells form typical papillary adenomas). |
抗原表达情况 | Blood Type B; Rh+ |
保藏机构 | ATCC; HTB-113 JCRB; JCRB1193 JCRB; NIHS0480 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 10,12 D2S1338 18,19 D3S1358 15 D5S818 11,13 D7S820 9,11 D8S1179 13,14 D13S317 11,16 D16S539 11,12 D18S51 16,20 D19S433 13 D21S11 30,31 FGA 21 PentaD 9,13 PentaE 11 TH01 6,7 TPOX 8,11 vWA 18 D6S1043 12,18 D12S391 18,19 D2S441 11,13 -
STR鉴定图
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参考文献
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Identification and validation of the important role of KIF11 in the development and progression of endometrial cancer (2025-01-13)
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-025-06081-6
影响因子 :6.1
引用产品: HEC-1-B 细胞 , Ishikawa 细胞
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NCAPG promotes the malignant progression of endometrioid cancer through LEF1/SEMA7A/PI3K-AKT (2025-01-01)
期刊:Journal of Cancer
影响因子 :3.3
引用产品: HEC-1-A 细胞 , HEC-1-B 细胞 , Ishikawa 细胞
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Study on the Active Components and Inhibiting Effect of Melastoma dodecandrum Lour. on Human Cervical Cancer Cells Based on Spectrum–Effect Relationship Analysis (2024-01-23)
期刊:Natural Product Communications
影响因子 :1.5
引用产品: Hela 细胞 , S-180 细胞 , HEC-1-B 细胞 , SK-OV-3 细胞
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O‑GlcNAcylation mediates endometrial cancer progression by regulating the Hippo‑YAP pathway (2023-06-19)
期刊:INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子 :5.2
引用产品: AN3 CA 细胞 , HEC-1-B 细胞
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Inhibition of ATM with KU-55933 Sensitizes Endometrial Cancer Cell Lines to Olaparib (2023-12-31)
期刊:OncoTargets and Therapy
影响因子 :4.0
引用产品: Ishikawa 细胞 , HEC-1-B 细胞 , AN3 CA 细胞 , KLE 细胞 , RL95-2 细胞
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Reduced FANCE Confers Genomic Instability and Malignant Behavior by Regulating Cell Cycle Progression in Endometrial Cancer (2023-08-28)
期刊:Journal of Cancer
影响因子 :3.9
引用产品: HEC-1-A 细胞 , HEC-1-B 细胞
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IGFBP?rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway (2023-03-03)
期刊:Experimental and Therapeutic Medicine
影响因子 :2.7
引用产品: Ishikawa 细胞 , HEC-1-A 细胞 , RL95-2 细胞 , HEC-1-B 细胞 , AN3 CA 细胞 , THP-1 细胞
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LINC01857 Exacerbates the Malignant Behaviors of Endometrial Carcinoma Cells by Sponging miR-19b-3p and Recruiting ELAVL1 to Upregulate MYCN (2023-03-28)
期刊:GYNECOLOGIC AND OBSTETRIC INVESTIGATION
影响因子 :2.1
引用产品: HEC-1-A 细胞 , HEC-1-B 细胞 , Ishikawa 细胞 , RL95-2 细胞
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Circ_0075960 targets the miR-202-5p/CTNND1 axis to promote the growth and migration of endometrial carcinoma cells via regulating Wnt/β-catenin signaling activity (2022-11-14)
期刊:Journal of Gynecologic Oncology
影响因子 :4.8
引用产品: HEC-1-B 细胞 , 特级胎牛血清 , 人子宫内膜基质细胞 , DMEM高糖 培养基 , Ishikawa 细胞 , RL95-2 细胞
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FANCD2 promotes the malignant behavior of endometrial cancer cells and its prognostic value (2022-10-15)
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2022.113388
影响因子 :4.2
引用产品: HEC-1-B 细胞 , Ishikawa 细胞
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Exosomal transfer of tumor-associated macrophage-derived hsa_circ_0001610 reduces radiosensitivity in endometrial cancer (2021-08-30)
期刊:Cell Death & Disease
DOI:10.1038/s41419-021-04087-8
影响因子 :9.0
引用产品: THP-1 细胞 , Ishikawa 细胞 , HEC-1-B 细胞
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N-methyladenosine reader YTHDF2-mediated long noncoding RNA FENDRR degradation promotes cell proliferation in endometrioid endometrial carcinoma (2021-03-10)
期刊:Laboratory Investigation
DOI:10.1038/s41374-021-00543-3
影响因子 :5.5
引用产品: Ishikawa 细胞 , HEC-1-B 细胞
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The Circadian Gene NPAS2 Act as a Putative Tumor Stimulative Factor for Uterine Corpus Endometrial Carcinoma (2021-12-22)
期刊:Cancer Management and Research
影响因子 :3.6
引用产品: HEC-1-B 细胞
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hsa_circ_0001610 knockdown modulates miR-646-STAT3 axis to suppress endometrial carcinoma progression (2021-04-20)
期刊:Journal Of Gene Medicine
DOI:10.1002/jgm.3337
影响因子 :3.5
引用产品: HEC-1-B 细胞 , KLE 细胞 , Ishikawa 细胞
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Pan-cancer multi-omics analyses reveal crosstalk between the Hippo and immune signaling pathways in the tumor microenvironment (2021-12-27)
期刊:Febs Letters
影响因子 :3.5
引用产品: HEC-1-B 细胞 , RL95-2 细胞
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